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Furthermore, it is more accurate compared to other equations at the low LDL-C cutpoints used for high-risk and very high-risk ASCVD patients and is valuable for deciding the need for additional lipid-lowering therapy. New equations for calculating sdLDL-C and LDL-TG use the same lipid parameters as for calculating LDL-C but offer additional insights into atherogenic lipoprotein burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>High plasma TG and very low LDL-C concentrations necessitate more accurate LDL-C calculations, which can be readily adopted without additional cost to improve ASCVD risk management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11883-026-01398-z","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T08:58:30Z","timestamp":1772009910000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["New Methods for Calculating LDL-Cholesterol and Related Biomarkers of Atherosclerotic Cardiovascular Disease Risk"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9479-0741","authenticated-orcid":false,"given":"Anna","family":"Wolska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeganeh","family":"Mansourian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Zubir\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Sampson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan T.","family":"Remaley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"issue":"32","key":"1398_CR1","doi-asserted-by":"publisher","first-page":"2459","DOI":"10.1093\/eurheartj\/ehx144","volume":"38","author":"BA Ference","year":"2017","unstructured":"Ference BA, Ginsberg HN, Graham I, et al. 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