{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:06:21Z","timestamp":1790762781206,"version":"4.1.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T00:00:00Z","timestamp":1099267200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Cardiol Rep"],"published-print":{"date-parts":[[2004,11]]},"DOI":"10.1007\/s11886-004-0054-3","type":"journal-article","created":{"date-parts":[[2007,5,26]],"date-time":"2007-05-26T08:21:20Z","timestamp":1180167680000},"page":"451-456","source":"Crossref","is-referenced-by-count":98,"title":["Hypothyroidism and dyslipidemia: Modern concepts and approaches"],"prefix":"10.1007","volume":"6","author":[{"given":"Elizabeth N.","family":"Pearce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"54_CR1","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJM193012252032601","volume":"203","author":"RL Mason","year":"1930","unstructured":"Mason RL, Hunt HM, Hurxthal L: Blood cholesterol values in hyperthyroidism and hypothyroidism. N Engl J Med 1930, 203:1273\u20131278.","journal-title":"N Engl J Med"},{"key":"54_CR2","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1210\/jcem.87.2.8182","volume":"87","author":"JG Hollowell","year":"2002","unstructured":"Hollowell JG, Staehling NW, Flanders WD, et al.: Serum TSH, T4, and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 2002, 87:489\u2013499.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR3","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1001\/archinte.1985.00360080056006","volume":"145","author":"CT Sawin","year":"1985","unstructured":"Sawin CT, Castelli WP, Hershman JM, et al.: The aging thyroid: Thyroid deficiency and the Framingham Study. Arch Intern Med 1985, 145:1386\u20131388.","journal-title":"Arch Intern Med"},{"key":"54_CR4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-2265.1995.tb01894.x","volume":"43","author":"MJP Vanderpump","year":"1995","unstructured":"Vanderpump MJP, Tunbridge WMG, French JM, et al.: The incidence of thyroid disorders in the community: A twenty-year follow-up of the Whickham Survey. Clin Endocrinol 1995, 43:55\u201368.","journal-title":"Clin Endocrinol"},{"key":"54_CR5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/07435800009040142","volume":"26","author":"JW Choi","year":"2000","unstructured":"Choi JW, Choi HS: The regulatory effects of thyroid hormone on the activity of 3-hydroxy-3-methylglutaryl coemzyme A reductase. Endocr Res 2000, 26:1\u201321.","journal-title":"Endocr Res"},{"key":"54_CR6","doi-asserted-by":"crossref","first-page":"34114","DOI":"10.1074\/jbc.M305417200","volume":"278","author":"DJ Shin","year":"2003","unstructured":"Shin DJ, Osborne TF: Thyroid hormone regulation and cholesterol metabolism are connected through sterol regulatory element-binding protein-2 (SREBP-2). J Biol Chem 2003, 278:34114\u201334118.","journal-title":"J Biol Chem"},{"key":"54_CR7","first-page":"140","volume":"83","author":"KCB Tan","year":"1998","unstructured":"Tan KCB, Shiu SWM, Kung AWC: Plasma cholsteryl ester transfer protein activity in hyper- and hypothyroidism. J Clin Endocrinol Metab 1998, 83:140\u2013143.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR8","first-page":"513","volume":"59","author":"KS Lam","year":"1986","unstructured":"Lam KS, Chan MK, Yeung RT: High-density lipoprotein cholesterol, hepatic lipase and lipoprotein lipase activities in thyroid dysfunction \u2014 effects of treatment. Q J Med 1986, 59:513\u2013521.","journal-title":"Q J Med"},{"key":"54_CR9","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1002\/hep.1840090610","volume":"9","author":"J Pauletzki","year":"1989","unstructured":"Pauletzki J, Stellaard F, Paumgartner G: Bile acid metabolism in human hyperthyroidism. Hepatology 1989, 9:852\u2013855.","journal-title":"Hepatology"},{"key":"54_CR10","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.0954-6820.1984.tb17678.x","volume":"215","author":"J Boberg","year":"1984","unstructured":"Boberg J, Dahlberg PA, Vessby B, Lithell H: Serum lipoprotein and apolipoprotein concentrations in patients with hyperthyroidism and the effect of treatment with carbimazole. Acta Med Scand 1984, 215:453\u2013459.","journal-title":"Acta Med Scand"},{"key":"54_CR11","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/S0025-6196(12)60694-6","volume":"68","author":"T O'Brien","year":"1993","unstructured":"O'Brien T, Dineen SF, O'Brien PC, Palumbo PJ: Hyperlipidemia in patients with primary and secondary hypothyroidism. May Clin Proc 1993, 68:860\u2013866.","journal-title":"May Clin Proc"},{"key":"54_CR12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1210\/jcem-66-1-51","volume":"66","author":"T Kuusi","year":"1988","unstructured":"Kuusi T, Taskinen MR, Nikkila EA: Lipoproteins, lipolytic enzymes and hormonal status in hypothyroid women at different levels of substitution. J Clin Endocrinol Metab 1988, 66:51\u201356.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR13","doi-asserted-by":"crossref","first-page":"837","DOI":"10.4065\/73.9.837","volume":"73","author":"ML Martinez-Triguero","year":"1998","unstructured":"Martinez-Triguero ML, Hernandez-Mijares A, Nguyen TT, et al.:Effect of thyroid hormone replacement on lipoprotein(a), lipids, and apolipoproteins in subjects with hypothyroidism. Mayo Clin Proc 1998, 73:837\u2013841. This study demonstrated the lipid effects of overt hypothyroidism and the effects of L-thyroxine therapy.","journal-title":"Mayo Clin Proc"},{"key":"54_CR14","first-page":"1206","volume":"86","author":"SJL Bakker","year":"2001","unstructured":"Bakker SJL, ter Maaten JC, Popp-Snijders C, et al.: The relationship between thyrotropin and low density lipoprotein cholesterol is modified by insulin sensitivity in healthy euthyroid subjects. J Clin Endocrinol Metab 2001, 86:1206\u20131211.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR15","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1056\/NEJM199510123331503","volume":"333","author":"B M\u00fcller","year":"1995","unstructured":"M\u00fcller B, Zulewski H, Huber P, et al.: Impaired action of thyroid hormone associated with smoking in women with hypothyroidism. N Engl J Med 1995, 333:964\u2013969.","journal-title":"N Engl J Med"},{"key":"54_CR16","first-page":"1209","volume":"76","author":"CJ Packard","year":"1993","unstructured":"Packard CJ, Shepherd J, Lindsay GM, et al.: Thyroid replacement therapy and its influence on postheparin plasma lipases and apolipoprotein-B metabolism in hypothyroidism. J Clin Endocrinol Metab 1993, 76:1209\u20131216.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR17","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1210\/jcem-49-5-726","volume":"49","author":"D Agdeppa","year":"1979","unstructured":"Agdeppa D, Macaron C, Mallik T, Schnuda ND: Plasma high density lipoprotein cholesterol in thyroid disease. J Clin Endocrinol Metab 1979, 49:726\u2013729.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR18","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0009-9120(82)90529-X","volume":"15","author":"M Aviram","year":"1982","unstructured":"Aviram M, Luboshitzky R, Brook JG: Lipid and lipoprotein pattern in thyroid dysfunction and the effect of therapy. Clin Biochem 1982, 15:62\u201366.","journal-title":"Clin Biochem"},{"key":"54_CR19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1365-2362.1981.tb01758.x","volume":"11","author":"H Lithell","year":"1981","unstructured":"Lithell H, Boberg J, Hellsing K, et al.: Serum lipoprotein and apolipoprotein concentrations and tissue lipoprotein-lipase activity in overt and subclinical hypothyroidism: the effect of substitution therapy. Eur J Clin Invest 1981, 11:3\u201310.","journal-title":"Eur J Clin Invest"},{"key":"54_CR20","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1046\/j.1365-2265.1996.739560.x","volume":"44","author":"BC Tanis","year":"1996","unstructured":"Tanis BC, Westendorp GJ, Smelt HM: Effect of thyroid substitution on hypercholesterolemia in patients with subclinical hypothyroidism: a reanalysis of intervention studies. Clin Endocrinol 1996, 44:643\u2013649.","journal-title":"Clin Endocrinol"},{"key":"54_CR21","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1089\/thy.2000.10.981","volume":"10","author":"H Vierhapper","year":"2000","unstructured":"Vierhapper H, Nardi A, Grosser P, et al.: Low-density lipoprotein cholesterol in subclinical hypothyroidism. Thyroid 2000, 10:981\u2013984.","journal-title":"Thyroid"},{"key":"54_CR22","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1001\/archinte.162.7.773","volume":"162","author":"AM Kanaya","year":"2002","unstructured":"Kanaya AM, Harris F, Volpato S, et al.: Association between thyroid dysfunction and total cholesterol level in an older biracial population: the Health, Aging, and Body Composition Study. Arch Intern Med 2002, 162:773\u2013779.","journal-title":"Arch Intern Med"},{"key":"54_CR23","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1001\/archinte.160.4.526","volume":"160","author":"GJ Canaris","year":"2000","unstructured":"Canaris GJ, Manowitz NR, Mayor G, Ridgway EC: The Colorado Thyroid Disease Prevalence Study. Arch Intern Med 2000, 160:526\u2013534. This cross-sectional study examined the prevalence of thyroid dysfunction and the relationships of thyroid dysfunction and serum lipid abnormalities in 25,862 subjects who attended a state health fair.","journal-title":"Arch Intern Med"},{"key":"54_CR24","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1089\/thy.2000.10.803","volume":"10","author":"T Tzotzas","year":"2000","unstructured":"Tzotzas T, Krassas GE, Konstantinidis T, Bougoulis M: Changes in lipoprotein(a) levels in overt and subclinical hypothyroidism before and during treatment. Thyroid 2000, 10:803\u2013808.","journal-title":"Thyroid"},{"key":"54_CR25","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0002-9343(02)01022-7","volume":"112","author":"WM Kong","year":"2002","unstructured":"Kong WM, Sheikh MH, Lumb PJ, et al.: A 6-month randomized trial of thyroxine treatment in women with mild subclinical hypothyroidism. Am J Med 2002, 112:348\u2013354.","journal-title":"Am J Med"},{"key":"54_CR26","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1210\/jcem.87.4.8378","volume":"87","author":"N Carracio","year":"2002","unstructured":"Carracio N, Ferrannini E, Monzani F: Lipoprotein profile in subclinical hypothyroidism: response to levothyroxine replacement, a randomized placebo-controlled study. J Clin Endocrinol Metab 2002, 87:1533\u20131538. This study examined lipoprotein profiles in subjects with subclinical hypothyroidism and reported elevations in LDL cholesterol that were reversible with L-thyroxine treatment.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR27","doi-asserted-by":"crossref","first-page":"4860","DOI":"10.1210\/jcem.86.10.7973","volume":"86","author":"C Meier","year":"2001","unstructured":"Meier C, Staub JJ, Roth CB, et al.: TSH-controlled L-thyroxine therapy reduced cholesterol levels and clinical symptoms in subclinical hypothyroidism: a double blind, placebocontrolled trial. J Clin Endocrinol Metab 2001, 86:4860\u20134866. This clinical trial of L-thyroxine therapy for subclinical hypothyroidism demonstrated decreases in serum LDL cholesterol concentrations following treatment, but failed to demonstrate significant differences in LDL, HDL, or triglycerides between the treatment and control groups.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR28","first-page":"2993","volume":"85","author":"MD Danese","year":"2000","unstructured":"Danese MD, Ladenson PW, Meinert CL, et al.: Effect of thyroxine therapy on serum lipoproteins in patients with mild thyroid failure: a quantitative review of the literature. J Clin Endocrinol Metab 2000, 85:2993\u20133001. This meta-analysis summarizes the effects of L-thyroxine treatment for subclinical hypothyroidism on serum lipid values across 13 studies including a total of 247 subjects. The authors conclude that L-T4 therapy significantly reduces serum total cholesterol and LDL cholesterol concentrations, but does not affect HDL or triglyceride concentrations.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR29","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1210\/jc.2003-031669","volume":"89","author":"F Monzani","year":"2004","unstructured":"Monzani F, Caraccio N, Kozakowa M, et al.: Effect of levothyroxine replacement on lipid profile and intima-media thickness in subclinical hypothyroidism: a double-blind, placebo-controlled study. J Clin Endocrinol Metab 2004, 89:2099\u20132106.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR30","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1046\/j.1365-2265.2003.01893.x","volume":"59","author":"T Nagasaki","year":"2003","unstructured":"Nagasaki T, Inaba M, Henmi Y, et al.: Decrease in carotid intima-media thickness in hypothyroid patients after normalization of thyroid function. Clin Endocrinol 2003, 59:607\u2013612.","journal-title":"Clin Endocrinol"},{"key":"54_CR31","doi-asserted-by":"crossref","first-page":"270","DOI":"10.7326\/0003-4819-132-4-200002150-00004","volume":"132","author":"AE Hak","year":"2000","unstructured":"Hak AE, Pols HAP, Visser TJ, et al.: Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam study. Ann Intern Med 2000, 132:270\u2013278. This study found an increased age-adjusted prevalence of aortic atherosclerosis (as measured by calcification visible on lateral lumbar spine radiographs) and MI in postmenopausal women with subclinical hypothyroidism compared with euthyroid women. However, when followed prospectively over an average of 4.6 years, there was no significant increase in relative risk for MI in the women with subclinical hypothyroidism.","journal-title":"Ann Intern Med"},{"key":"54_CR32","first-page":"562","volume":"80","author":"F Pazos","year":"1995","unstructured":"Pazos F, Alvarez JJ, Rubies-Prat J, et al.: Long-term thyroid replacement therapy and levels of lipoprotein(a) and other lipoproteins. J Clin Endocrinol Metab 1995, 80:562\u2013566.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR33","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1089\/105072503321669857","volume":"13","author":"HJ Milionis","year":"2003","unstructured":"Milionis HJ, Efstathiadou Z, Tselepis AD, et al.: Lipoprotein(a) levels and apolipoprotein (a) isoform size in patients with subclinical hypothyroidism: effect of treatment with levothyroxine. Thyroid 2003, 13:365\u2013369.","journal-title":"Thyroid"},{"key":"54_CR34","first-page":"2921","volume":"83","author":"KCB Tan","year":"1998","unstructured":"Tan KCB, Shiu SWM, Kung AWC: Effect of thyroid dysfunction on high-density lipoprotein subfraction metabolism: roles of hepatic lipase and cholesteryl ester transfer protein. J Clin Endocrinol Metab 1998, 83:2921\u20132924.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR35","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.1365-2265.1997.d01-1753.x","volume":"46","author":"T O'Brien","year":"1997","unstructured":"O'Brien T, Katz K, Hodge D, et al.: The effect of the treatment of hypothyroidism and hyperthyroidism on plasma lipids and apolipoproteins AI, AII, and E. Clin Endocrinol 1997, 46:17\u201320.","journal-title":"Clin Endocrinol"},{"key":"54_CR36","doi-asserted-by":"crossref","first-page":"2532","DOI":"10.1210\/jcem.84.7.5812","volume":"84","author":"M Weintraub","year":"1999","unstructured":"Weintraub M, Grosskopf I, Trostanesky Y, et al.: Thyroxine replacement therapy enhances clearance of chylomicron remnants in patients with hypothyroidism. J Clin Endocrinol Metab 1999, 84:2532\u20132536.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR37","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1046\/j.1365-2265.2003.01762.x","volume":"58","author":"M Ito","year":"2003","unstructured":"Ito M, Takamatsu J, Matsuo T, et al.: Serum concentrations of remnant-like particles in hypothyroid patients before and after thyroxine replacement. Clin Endocrinol 2003, 58:621\u2013626.","journal-title":"Clin Endocrinol"},{"key":"54_CR38","first-page":"3241","volume":"82","author":"V Sundaram","year":"1997","unstructured":"Sundaram V, Hanna HF, Koneru L, et al.: Both hypothyroidism and hyperthyroidism enhance low density lipoprotein oxidation. J Clin Endocrinol Metab 1997, 82:3241\u20133244.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR39","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1210\/jcem.83.5.4759","volume":"83","author":"T Diekman","year":"1998","unstructured":"Diekman T, Demacker PN, Kastelein JJP, et al.: Increased oxidizability of low-density lipoproteins in hypothyroidism. J Clin Endocrinol Metab 1998, 83:1752\u20131755.","journal-title":"J Clin Endocrinol Metab"},{"key":"54_CR40","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1089\/105072502320908349","volume":"12","author":"LH Duntas","year":"2002","unstructured":"Duntas LH, Mantzou E, Koutras DA: Circulating levels of oxidized low-density lipoprotein in overt and mild hypothyroidism. Thyroid 2002, 12:1003\u20131007.","journal-title":"Thyroid"},{"key":"54_CR41","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1345\/aph.1C376","volume":"37","author":"BA Ineck","year":"2003","unstructured":"Ineck BA, Ng TMH: Effects of subclinical hypothyroidism and its treatment on serum lipids. Ann Pharmacother 2003, 37:725\u2013730.","journal-title":"Ann Pharmacother"},{"key":"54_CR42","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1001\/archinte.160.11.1573","volume":"160","author":"PW Ladenson","year":"2000","unstructured":"Ladenson PW, Singer PA, Ain KB, et al.: American Thyroid Association guidelines for detection of thyroid dysfunction. Arch Int Med 2000, 160:1573\u20131575.","journal-title":"Arch Int Med"},{"key":"54_CR43","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1001\/jama.1996.03540040029029","volume":"276","author":"MD Danese","year":"1996","unstructured":"Danese MD, Powe NR, Sawin Ct, Ladenson PW: Screening for mild thyroid failure at the periodic health examination: a decision and cost-effectiveness analysis. JAMA 1996, 276:285\u2013292.","journal-title":"JAMA"},{"key":"54_CR44","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1001\/jama.289.13.1681","volume":"289","author":"PD Thompson","year":"2003","unstructured":"Thompson PD, Clarkson P, Karras RH: Statin-associated myopathy. JAMA 2003, 289:1681\u20131690.","journal-title":"JAMA"},{"key":"54_CR45","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1001\/jama.291.2.228","volume":"291","author":"MI Surks","year":"2004","unstructured":"Surks MI, Ortiz E, Daniels GH, et al.: Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA 2004, 291:228\u2013238. This consensus report reviews the data regarding the risks and benefits of L-thyroxine treatment for subclinical hypothyroidism, and provides treatment guidelines.","journal-title":"JAMA"},{"key":"54_CR46","first-page":"39","volume":"23","author":"A Azezli","year":"2000","unstructured":"Azezli A, Ozbey N, Taskale, et al.: The comparison of L-thyroxine versus L-thyroxine and statin combinations in lipid status in patients with subclinical hypothyroidism. J Endocrinol Invest 2000, 23:39.","journal-title":"J Endocrinol Invest"},{"key":"54_CR47","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.tem.2004.03.008","volume":"15","author":"JD Baxter","year":"2004","unstructured":"Baxter JD, Webb P, Grover G, Scanlan TS: Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weight. Trends Endocrinol Metab 2004, 15:154\u2013157. This review summarizes the beneficial and deleterious effects of thyroid hormone, and describes progress in the development of a selective thyroid hormone receptor modulator designed to elicit only the beneficial thyroid hormone effects.","journal-title":"Trends Endocrinol Metab"},{"key":"54_CR48","doi-asserted-by":"crossref","first-page":"10067","DOI":"10.1073\/pnas.1633737100","volume":"100","author":"GJ Grover","year":"2003","unstructured":"Grover GJ, Mellstr\u00f6m K, Ye L, et al.: Selective thyroid hormone receptor-b activation: a strategy for reduction of weight, cholesterol, and lipoprotein(a) with reduced cardiovascular liability. Proc Natl Acad Sci U S A 2003, 100:10067\u201310072.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"54_CR49","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1124\/mol.52.3.542","volume":"52","author":"AH Taylor","year":"1997","unstructured":"Taylor AH, Stephan ZF, Steele RE, Wong NCW: Beneficial effects of a novel thyromimetic in lipoprotein metabolism. Mol Pharmacol 1997, 52:542\u2013547.","journal-title":"Mol Pharmacol"}],"container-title":["Current Cardiology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-004-0054-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11886-004-0054-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-004-0054-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T23:55:59Z","timestamp":1559433359000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11886-004-0054-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["54"],"URL":"https:\/\/doi.org\/10.1007\/s11886-004-0054-3","relation":{},"ISSN":["1523-3782","1534-3170"],"issn-type":[{"value":"1523-3782","type":"print"},{"value":"1534-3170","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,11]]}}}