{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T05:06:29Z","timestamp":1761195989696},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2016,11,11]],"date-time":"2016-11-11T00:00:00Z","timestamp":1478822400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Cardiol Rep"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s11886-016-0785-y","type":"journal-article","created":{"date-parts":[[2016,11,11]],"date-time":"2016-11-11T08:04:25Z","timestamp":1478851465000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Roads, Maps, and Destinations: the Journey of Left Ventricular Assist Device Implantation in Ambulatory Patients with Advanced Heart Failure"],"prefix":"10.1007","volume":"18","author":[{"given":"Barry H.","family":"Trachtenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry D.","family":"Estep","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,11,11]]},"reference":[{"key":"785_CR1","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1056\/NEJMoa012175","volume":"345","author":"EA Rose","year":"2001","unstructured":"Rose EA, Gelijns AC, Moskowitz AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435\u201343.","journal-title":"N Engl J Med"},{"key":"785_CR2","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1056\/NEJMoa0909938","volume":"361","author":"MS Slaughter","year":"2009","unstructured":"Slaughter MS, Rogers JG, Milano CA, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009;361:2241\u201351.","journal-title":"N Engl J Med"},{"key":"785_CR3","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.healun.2015.10.003","volume":"34","author":"JK Kirklin","year":"2015","unstructured":"Kirklin JK, Naftel DC, Pagani FD, et al. Seventh INTERMACS annual report: 15,000 patients and counting. J Heart Lung Transplant. 2015;34:1495\u2013504.","journal-title":"J Heart Lung Transplant"},{"key":"785_CR4","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.healun.2009.02.015","volume":"28","author":"LW Stevenson","year":"2009","unstructured":"Stevenson LW, Pagani FD, Young JB, et al. INTERMACS profiles of advanced heart failure: the current picture. J Heart Lung Transplant. 2009;28:535\u201341.","journal-title":"J Heart Lung Transplant"},{"key":"785_CR5","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/j.jacc.2015.07.075","volume":"66","author":"JD Estep","year":"2015","unstructured":"Estep JD, Starling RC, Horstmanshof DA, et al. Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients: results from the ROADMAP study. J Am Coll Cardiol. 2015;66:1747\u201361. This study is the only prospective trial to date to directly compare the use of LVAD vs. medical management in ambulatory non-inotrope dependent patients (i.e. INTERMACS profiles 4-7).","journal-title":"J Am Coll Cardiol"},{"key":"785_CR6","doi-asserted-by":"crossref","unstructured":"Rogers JG, Boyle AJ, O'Connell JB et al. Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients: design and rationale of the ROADMAP clinical trial. Am Heart J 2015; 169:205-210 e220.","DOI":"10.1016\/j.ahj.2014.11.004"},{"key":"785_CR7","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.healun.2010.10.016","volume":"30","author":"AJ Boyle","year":"2011","unstructured":"Boyle AJ, Ascheim DD, Russo MJ, et al. Clinical outcomes for continuous-flow left ventricular assist device patients stratified by pre-operative INTERMACS classification. J Heart Lung Transplant. 2011;30:402\u20137.","journal-title":"J Heart Lung Transplant"},{"key":"785_CR8","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.healun.2013.10.017","volume":"33","author":"KL Grady","year":"2014","unstructured":"Grady KL, Naftel D, Stevenson L, et al. Overall quality of life improves to similar levels after mechanical circulatory support regardless of severity of heart failure before implantation. J Heart Lung Transplant. 2014;33:412\u201321.","journal-title":"J Heart Lung Transplant"},{"key":"785_CR9","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1016\/j.jacc.2014.01.053","volume":"63","author":"UP Jorde","year":"2014","unstructured":"Jorde UP, Kushwaha SS, Tatooles AJ, et al. Results of the destination therapy post-food and drug administration approval study with a continuous flow left ventricular assist device: a prospective study using the INTERMACS registry (Interagency Registry for Mechanically Assisted Circulatory Support). J Am Coll Cardiol. 2014;63:1751\u20137.","journal-title":"J Am Coll Cardiol"},{"key":"785_CR10","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.healun.2014.04.010","volume":"33","author":"JK Kirklin","year":"2014","unstructured":"Kirklin JK, Naftel DC, Pagani FD, et al. Sixth INTERMACS annual report: a 10,000-patient database. J Heart Lung Transplant. 2014;33:555\u201364.","journal-title":"J Heart Lung Transplant"},{"key":"785_CR11","doi-asserted-by":"crossref","unstructured":"Stewart GC, Teuteberg J.J., Kittelson M et al. INTERMACS profiling identifies risk of death or VAD among medically-managed advanced heart failure patients. J Heart Lung Transplant 2013:S133.","DOI":"10.1016\/j.healun.2013.01.296"},{"key":"785_CR12","doi-asserted-by":"crossref","unstructured":"Ambardekar AV, Forde-McLean RC, Kittleson MM et al. High early event rates in patients with questionable eligibility for advanced heart failure therapies: Results from the Medical Arm of Mechanically Assisted Circulatory Support (Medamacs) Registry. J Heart Lung Transplant 2016. This study shows a high mortality at less than one year in INTERMACS 4-7 heart failure patients who are deemed to have poor eligbility for transplant or LVAD.","DOI":"10.1016\/j.healun.2016.01.014"},{"key":"785_CR13","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1016\/j.healun.2015.01.141","volume":"34","author":"GC Stewart","year":"2015","unstructured":"Stewart GC, Mountis MM, Kittelson MM. Early reassessment of ambulatory advanced heart failure detects high-risk trajectories along a dynamic baseline. J Heart Lung Transplant. 2015;34:S56.","journal-title":"J Heart Lung Transplant"},{"key":"785_CR14","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.cardfail.2010.06.414","volume":"16","author":"JT Baldwin","year":"2010","unstructured":"Baldwin JT, Mann DL. NHLBI\u2019s program for VAD therapy for moderately advanced heart failure: the REVIVE-IT pilot trial. J Card Fail. 2010;16:855\u20138.","journal-title":"J Card Fail"},{"key":"785_CR15","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1056\/NEJMoa1313385","volume":"370","author":"RC Starling","year":"2014","unstructured":"Starling RC, Moazami N, Silvestry SC, et al. Unexpected abrupt increase in left ventricular assist device thrombosis. N Engl J Med. 2014;370:33\u201340.","journal-title":"N Engl J Med"},{"key":"785_CR16","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/j.healun.2015.10.024","volume":"34","author":"JK Kirklin","year":"2015","unstructured":"Kirklin JK, Naftel DC, Pagani FD, et al. Pump thrombosis in the Thoratec HeartMate II device: an update analysis of the INTERMACS Registry. J Heart Lung Transplant. 2015;34:1515\u201326.","journal-title":"J Heart Lung Transplant"},{"key":"785_CR17","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1016\/j.jacc.2015.08.852","volume":"66","author":"CR Bruce","year":"2015","unstructured":"Bruce CR, Blumenthal-Barby JS, Meyers D. Benefits and challenges of early introduction of left ventricular assist device placement: a patient-centered perspective. J Am Coll Cardiol. 2015;66:1762\u20135.","journal-title":"J Am Coll Cardiol"},{"key":"785_CR18","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1016\/j.healun.2015.07.009","volume":"34","author":"GC Stewart","year":"2015","unstructured":"Stewart GC, Kittleson MM, Cowger JA, et al. Who wants a left ventricular assist device for ambulatory heart failure? Early insights from the MEDAMACS screening pilot. J Heart Lung Transplant. 2015;34:1630\u20133.","journal-title":"J Heart Lung Transplant"}],"container-title":["Current Cardiology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-016-0785-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11886-016-0785-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-016-0785-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,15]],"date-time":"2019-09-15T13:35:50Z","timestamp":1568554550000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11886-016-0785-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,11]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["785"],"URL":"https:\/\/doi.org\/10.1007\/s11886-016-0785-y","relation":{},"ISSN":["1523-3782","1534-3170"],"issn-type":[{"value":"1523-3782","type":"print"},{"value":"1534-3170","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,11]]},"article-number":"132"}}