{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T10:58:49Z","timestamp":1793444329266,"version":"4.5.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Cardiol Rep"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1007\/s11886-019-1098-8","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T06:09:18Z","timestamp":1551334158000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Recent Advances in Congenital Heart Surgery: Alternative Perfusion Strategies for Infant Aortic Arch Repair"],"prefix":"10.1007","volume":"21","author":[{"given":"Andrew J.","family":"Lodge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas D.","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph W.","family":"Turek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,2,28]]},"reference":[{"issue":"9","key":"1098_CR1","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1056\/NEJM199503023320901","volume":"332","author":"DC Bellinger","year":"1995","unstructured":"Bellinger DC, Jonas RA, Rappaport LA, Wypij D, Wernovsky G, Kuban KC, et al. Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. N Engl J Med. 1995;332(9):549\u201355. \n                      https:\/\/doi.org\/10.1056\/NEJM199503023320901\n                      \n                    .","journal-title":"N Engl J Med"},{"issue":"3","key":"1098_CR2","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1542\/peds.111.3.592","volume":"111","author":"RR Clancy","year":"2003","unstructured":"Clancy RR, McGaurn SA, Wernovsky G, Gaynor JW, Spray TL, Norwood WI, et al. Risk of seizures in survivors of newborn heart surgery using deep hypothermic circulatory arrest. Pediatrics. 2003;111(3):592\u2013601.","journal-title":"Pediatrics"},{"key":"1098_CR3","doi-asserted-by":"publisher","unstructured":"Gil-Ruiz Gil-Esparza MA, Alcaraz Romero AJ, Romero Otero A, Gil Villanueva N, Sanavia Moran E, Rodriguez Sanchez de la Blanca A et al. Prognostic relevance of early AKI according to pRIFLE criteria in children undergoing cardiac surgery. Pediatr Nephrol 2014;29(7):1265\u20131272. doi:\n                      https:\/\/doi.org\/10.1007\/s00467-014-2757-z\n                      \n                    .","DOI":"10.1007\/s00467-014-2757-z"},{"issue":"4","key":"1098_CR4","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/S0022-5223(94)70378-7","volume":"107","author":"AJ Plessis du","year":"1994","unstructured":"du Plessis AJ, Treves ST, Hickey PR, O'Tuama L, Barlow CF, Costello J, et al. Regional cerebral perfusion abnormalities after cardiac operations. Single photon emission computed tomography (SPECT) findings in children with postoperative movement disorders. J Thorac Cardiovasc Surg. 1994;107(4):1036\u201343.","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"3","key":"1098_CR5","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1001\/archpedi.1990.02150270119040","volume":"144","author":"PC Ferry","year":"1990","unstructured":"Ferry PC. Neurologic sequelae of open-heart surgery in children. An \u2018irritating question\u2019. Am J Dis Child. 1990;144(3):369\u201373.","journal-title":"Am J Dis Child"},{"key":"1098_CR6","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1053\/pcsu.2002.31493","volume":"5","author":"RA Jonas","year":"2002","unstructured":"Jonas RA. Deep hypothermic circulatory arrest: current status and indications. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2002;5:76\u201388. \n                      https:\/\/doi.org\/10.1053\/pcsu.2002.31493\n                      \n                    .","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu."},{"issue":"1","key":"1098_CR7","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/S0003-4975(99)00521-4","volume":"68","author":"SM Langley","year":"1999","unstructured":"Langley SM, Chai PJ, Miller SE, Mault JR, Jaggers JJ, Tsui SS, et al. Intermittent perfusion protects the brain during deep hypothermic circulatory arrest. Ann Thorac Surg. 1999;68(1):4\u201312 discussion \u22123.","journal-title":"Ann Thorac Surg"},{"key":"1098_CR8","first-page":"314","volume":"44","author":"JR Mault","year":"1992","unstructured":"Mault JR, Whitaker EG, Heinle JS, Lodge AJ, Greeley WJ, Ungerleider RM. Intermittent perfusion during hypothermic circulatory arrest: a new and effective technique for cerebral protection. Surg Forum. 1992;44:314.","journal-title":"Surg Forum"},{"issue":"1","key":"1098_CR9","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/0003-4975(94)90372-7","volume":"57","author":"JR Mault","year":"1994","unstructured":"Mault JR, Whitaker EG, Heinle JS, Lodge AJ, Greeley WJ, Ungerleider RM. Cerebral metabolic effects of sequential periods of hypothermic circulatory arrest. Ann Thorac Surg. 1994;57(1):96\u2013100 discussion \u22121.","journal-title":"Ann Thorac Surg"},{"key":"1098_CR10","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1053\/j.pcsu.2008.01.003","volume":"11","author":"DP Nelson","year":"2008","unstructured":"Nelson DP, Andropoulos DB, Fraser CD Jr. Perioperative neuroprotective strategies. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2008;11:49\u201356. \n                      https:\/\/doi.org\/10.1053\/j.pcsu.2008.01.003\n                      \n                    .","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"issue":"1","key":"1098_CR11","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.athoracsur.2014.02.042","volume":"98","author":"C Pizarro","year":"2014","unstructured":"Pizarro C, Sood ED, Kerins P, Duncan D, Davies RR, Woodford E. Neurodevelopmental outcomes after infant cardiac surgery with circulatory arrest and intermittent perfusion. Ann Thorac Surg. 2014;98(1):119\u201324. \n                      https:\/\/doi.org\/10.1016\/j.athoracsur.2014.02.042\n                      \n                    .","journal-title":"Ann Thorac Surg"},{"key":"1098_CR12","first-page":"211","volume":"45","author":"EG Whitaker","year":"1993","unstructured":"Whitaker EG, Mault JR, Heinle JS, Lodge AJ, Greeley WJ, Jobsis-VanderVliet FF, et al. Near-infrared spectroscopy for non-invasive cerebral metabolic monitoring during congenital heart repair. Surg Forum. 1993;45:211\u20132.","journal-title":"Surg Forum"},{"issue":"3","key":"1098_CR13","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1177\/0267659109346661","volume":"24","author":"H Zhang","year":"2009","unstructured":"Zhang H, Cheng P, Hou J, Li L, Liu H, Liu R, et al. Regional cerebral perfusion for surgical correction of neonatal aortic arch obstruction. Perfusion. 2009;24(3):185\u20139. \n                      https:\/\/doi.org\/10.1177\/0267659109346661\n                      \n                    .","journal-title":"Perfusion"},{"issue":"3","key":"1098_CR14","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1016\/j.athoracsur.2012.10.029","volume":"95","author":"G Amir","year":"2013","unstructured":"Amir G, Frenkel G, Shukrun G, Gogia O, Bachar O, Bruckheimer E, et al. Direct innominate artery cannulation for antegrade cerebral perfusion in neonates undergoing arch reconstruction. Ann Thorac Surg. 2013;95(3):956\u201361. \n                      https:\/\/doi.org\/10.1016\/j.athoracsur.2012.10.029\n                      \n                    .","journal-title":"Ann Thorac Surg"},{"key":"1098_CR15","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1053\/j.pcsu.2007.12.004","volume":"11","author":"SP Malhotra","year":"2008","unstructured":"Malhotra SP, Hanley FL. Routine continuous perfusion for aortic arch reconstruction in the neonate. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2008;11:57\u201360. \n                      https:\/\/doi.org\/10.1053\/j.pcsu.2007.12.004\n                      \n                    .","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu."},{"issue":"4","key":"1098_CR16","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1177\/2150135113497767","volume":"4","author":"T Nasirov","year":"2013","unstructured":"Nasirov T, Mainwaring RD, Reddy VM, Sleasman J, Margetson T, Hanley FL. Innominate artery cannulation and antegrade cerebral perfusion for aortic arch reconstruction in infants and children. World J Pediatr Congenit Heart Surg. 2013;4(4):356\u201361. \n                      https:\/\/doi.org\/10.1177\/2150135113497767\n                      \n                    .","journal-title":"World J Pediatr Congenit Heart Surg"},{"issue":"6","key":"1098_CR17","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1016\/j.jtcvs.2012.03.008","volume":"144","author":"SO Algra","year":"2012","unstructured":"Algra SO, Schouten AN, van Oeveren W, van der Tweel I, Schoof PH, Jansen NJ, et al. Low-flow antegrade cerebral perfusion attenuates early renal and intestinal injury during neonatal aortic arch reconstruction. J Thorac Cardiovasc Surg. 2012;144(6):1323\u20138, 8 e1\u20132. \n                      https:\/\/doi.org\/10.1016\/j.jtcvs.2012.03.008\n                      \n                    .","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"2","key":"1098_CR18","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.jtcvs.2011.08.006","volume":"143","author":"SO Algra","year":"2012","unstructured":"Algra SO, Kornmann VN, van der Tweel I, Schouten AN, Jansen NJ, Haas F. Increasing duration of circulatory arrest, but not antegrade cerebral perfusion, prolongs postoperative recovery after neonatal cardiac surgery. J Thorac Cardiovasc Surg. 2012;143(2):375\u201382. \n                      https:\/\/doi.org\/10.1016\/j.jtcvs.2011.08.006\n                      \n                    .","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"2","key":"1098_CR19","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.athoracsur.2012.04.070","volume":"95","author":"DB Andropoulos","year":"2013","unstructured":"Andropoulos DB, Easley RB, Brady K, McKenzie ED, Heinle JS, Dickerson HA, et al. Neurodevelopmental outcomes after regional cerebral perfusion with neuromonitoring for neonatal aortic arch reconstruction. Ann Thorac Surg. 2013;95(2):648\u201354; discussion 54\u20135. \n                      https:\/\/doi.org\/10.1016\/j.athoracsur.2012.04.070\n                      \n                    .","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"1098_CR20","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1016\/j.jtcvs.2006.11.029","volume":"133","author":"CS Goldberg","year":"2007","unstructured":"Goldberg CS, Bove EL, Devaney EJ, Mollen E, Schwartz E, Tindall S, et al. A randomized clinical trial of regional cerebral perfusion versus deep hypothermic circulatory arrest: outcomes for infants with functional single ventricle. J Thorac Cardiovasc Surg. 2007;133(4):880\u20137. \n                      https:\/\/doi.org\/10.1016\/j.jtcvs.2006.11.029\n                      \n                    .","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"3","key":"1098_CR21","doi-asserted-by":"publisher","first-page":"e45","DOI":"10.1093\/ejcts\/ezv235","volume":"48","author":"IA Kornilov","year":"2015","unstructured":"\u2022 Kornilov IA, Sinelnikov YS, Soinov IA, Ponomarev DN, Kshanovskaya MS, Krivoshapkina AA, et al. Outcomes after aortic arch reconstruction for infants: deep hypothermic circulatory arrest versus moderate hypothermia with selective antegrade cerebral perfusion. Eur J Cardiothorac Surg. 2015;48(3):e45\u201350. \n                      https:\/\/doi.org\/10.1093\/ejcts\/ezv235\n                      \n                     This study is important because it provided evidence that RCP provides protection from neurolgic injury compared to DHCA. Interestingly, however, it showed a higher incidence of renal insufficiency in the RCP patients indicating the attention to flow rate, temperature, and adequate distal perfusion is necessary.","journal-title":"Eur J Cardiothorac Surg"},{"issue":"2","key":"1098_CR22","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1161\/CIRCULATIONAHA.113.003312","volume":"129","author":"SO Algra","year":"2014","unstructured":"Algra SO, Jansen NJ, van der Tweel I, Schouten AN, Groenendaal F, Toet M, et al. Neurological injury after neonatal cardiac surgery: a randomized, controlled trial of 2 perfusion techniques. Circulation. 2014;129(2):224\u201333. \n                      https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.113.003312\n                      \n                    .","journal-title":"Circulation"},{"issue":"6","key":"1098_CR23","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1097\/IMI.0000000000000211","volume":"10","author":"AM Carlson","year":"2015","unstructured":"\u2022 Carlson AM, Tcheng JW, Holgren SE, Turek JW. Beating-heart sliding arch aortoplasty for arch hypoplasia beyond infancy. Innovations (Phila). 2015;10(6):441\u20133. \n                      https:\/\/doi.org\/10.1097\/IMI.0000000000000211\n                      \n                     This report is important in that it illustrates the successful use of a beating heart technique with continuous coronary perfusion for complex aortic arch reconstruction in children.","journal-title":"Innovations (Phila)"},{"issue":"5","key":"1098_CR24","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1097\/01.mat.0000235276.77489.bb","volume":"52","author":"Y Kotani","year":"2006","unstructured":"Kotani Y, Ishino K, Kasahara S, Yoshizumi K, Honjo O, Kawada M, et al. Continuous cerebral and myocardial perfusion during aortic arch repair in neonates and infants. ASAIO J. 2006;52(5):536\u20138. \n                      https:\/\/doi.org\/10.1097\/01.mat.0000235276.77489.bb\n                      \n                    .","journal-title":"ASAIO J"},{"issue":"1","key":"1098_CR25","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.athoracsur.2013.03.049","volume":"96","author":"JW Turek","year":"2013","unstructured":"Turek JW, Hanfland RA, Davenport TL, Torres JE, Duffey DA, Patel SS, et al. Norwood reconstruction using continuous coronary perfusion: a safe and translatable technique. Ann Thorac Surg. 2013;96(1):219\u201323: discussion 23-4. \n                      https:\/\/doi.org\/10.1016\/j.athoracsur.2013.03.049\n                      \n                    .","journal-title":"Ann Thorac Surg"},{"issue":"3","key":"1098_CR26","doi-asserted-by":"publisher","first-page":"114","DOI":"10.21037\/tp.2016.06.03","volume":"5","author":"B Gupta","year":"2016","unstructured":"Gupta B, Dodge-Khatami A, Tucker J, Taylor MB, Maposa D, Urencio M, et al. Antegrade cerebral perfusion at 25\u00a0\u00b0C for arch reconstruction in newborns and children preserves perioperative cerebral oxygenation and serum creatinine. Transl Pediatr. 2016;5(3):114\u201324. \n                      https:\/\/doi.org\/10.21037\/tp.2016.06.03\n                      \n                    .","journal-title":"Transl Pediatr"},{"issue":"3","key":"1098_CR27","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1016\/j.athoracsur.2011.03.122","volume":"92","author":"AN Karavas","year":"2011","unstructured":"\u2022 Karavas AN, Deschner BW, Scott JW, Mettler BA, Bichell DP. Three-region perfusion strategy for aortic arch reconstruction in the Norwood. Ann Thorac Surg. 2011;92(3):1138\u201340. \n                      https:\/\/doi.org\/10.1016\/j.athoracsur.2011.03.122\n                      \n                     This is a report of the successful use of three region perfusion (simultaneous perfusion of the heart, brain, and lower body during the Norwood procedure. The Norwood procedure is a complex operation performed in a neonate involving reconstruction of the aortic arch.","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"1098_CR28","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/j.jtcvs.2010.03.034","volume":"140","author":"SK Rajagopal","year":"2010","unstructured":"Rajagopal SK, Emani SM, Roy N, Westgate L, Bacha EA. Acute kidney injury and regional abdominal perfusion during neonatal aortic arch reconstruction. J Thorac Cardiovasc Surg. 2010;140(2):453\u20138. \n                      https:\/\/doi.org\/10.1016\/j.jtcvs.2010.03.034\n                      \n                    .","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"6","key":"1098_CR29","doi-asserted-by":"publisher","first-page":"2054","DOI":"10.1016\/j.athoracsur.2017.04.037","volume":"104","author":"MA Raees","year":"2017","unstructured":"Raees MA, Morgan CD, Pinto VL, Westrick AC, Shannon CN, Christian KG, et al. Neonatal aortic arch reconstruction with direct splanchnic perfusion avoids deep hypothermia. Ann Thorac Surg. 2017;104(6):2054\u201363. \n                      https:\/\/doi.org\/10.1016\/j.athoracsur.2017.04.037\n                      \n                    .","journal-title":"Ann Thorac Surg"},{"issue":"5","key":"1098_CR30","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.1016\/j.athoracsur.2013.06.033","volume":"96","author":"JM Hammel","year":"2013","unstructured":"Hammel JM, Deptula JJ, Karamlou T, Wedemeyer E, Abdullah I, Duncan KF. Newborn aortic arch reconstruction with descending aortic cannulation improves postoperative renal function. Ann Thorac Surg. 2013;96(5):1721\u20136; discussion 6. \n                      https:\/\/doi.org\/10.1016\/j.athoracsur.2013.06.033\n                      \n                    .","journal-title":"Ann Thorac Surg"}],"container-title":["Current Cardiology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-019-1098-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11886-019-1098-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-019-1098-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T00:22:17Z","timestamp":1582849337000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11886-019-1098-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,28]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["1098"],"URL":"https:\/\/doi.org\/10.1007\/s11886-019-1098-8","relation":{},"ISSN":["1523-3782","1534-3170"],"issn-type":[{"value":"1523-3782","type":"print"},{"value":"1534-3170","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,28]]},"assertion":[{"value":"28 February 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"Andrew J. Lodge, Nicholas D. Andersen, and Joseph W. Turek declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"All cited studies performed by the authors have been approved by the appropriate institutional and\/or national research ethics committee and have been performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}],"article-number":"13"}}