{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:09:10Z","timestamp":1788775750382,"version":"build-2803163510"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Cardiol Rep"],"DOI":"10.1007\/s11886-026-02413-0","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T09:25:13Z","timestamp":1788773113000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The 2025 AHA\/ACC Hypertension Guidelines: Key Updates, Historical Context, and Clinical Implications"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0334-9876","authenticated-orcid":false,"given":"John M.","family":"Giacona","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanpen","family":"Vongpatanasin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"2413_CR1","unstructured":"Jones DW, Ferdinand KC, Taler SJ, Johnson HM, Shimbo D, Abdalla M, et al. AHA\/ACC\/AANP\/AAPA\/ABC\/ACCP\/ACPM\/AGS\/AMA\/ASPC\/NMA\/PCNA\/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines. Hypertension. 2025."},{"key":"2413_CR2","unstructured":"Fryar CD, Kit B, Carroll MD, Afful J, Hypertension Prevalence. Awareness, Treatment, and Control Among Adults Age 18 and Older: United States, August 2021-August 2023. NCHS Data Brief. 2024(511)."},{"issue":"2","key":"2413_CR3","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1093\/ajh\/hpae141","volume":"38","author":"ST Hardy","year":"2025","unstructured":"Hardy ST, Jaeger BC, Foti K, Ghazi L, Wozniak G, Muntner P. Trends in Blood Pressure Control among US Adults With Hypertension, 2013\u20132014 to 2021\u20132023. Am J Hypertens. 2025;38(2):120\u20138.","journal-title":"Am J Hypertens"},{"issue":"3","key":"2413_CR4","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1001\/jama.1977.03270300059008","volume":"237","author":"Report of the Joint National Committee on","year":"1977","unstructured":"Report of the Joint National Committee on. Detection, Evaluation, and Treatment of High Blood Pressure. A cooperative study. JAMA. 1977;237(3):255\u201361.","journal-title":"JAMA"},{"issue":"10","key":"2413_CR5","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1001\/archinte.1980.00330210028018","volume":"140","author":"The 1980 report of the Joint National Committee on","year":"1980","unstructured":"The 1980 report of the Joint National Committee on. Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1980;140(10):1280\u20135.","journal-title":"Arch Intern Med"},{"issue":"5","key":"2413_CR6","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1001\/archinte.1984.00350170211032","volume":"144","author":"The 1984 Report of the Joint National Committee on","year":"1984","unstructured":"The 1984 Report of the Joint National Committee on. Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1984;144(5):1045\u201357.","journal-title":"Arch Intern Med"},{"issue":"5","key":"2413_CR7","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1001\/archinte.1988.00380050029006","volume":"148","author":"The 1988 report of the Joint National Committee on","year":"1988","unstructured":"The 1988 report of the Joint National Committee on. Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1988;148(5):1023\u201338.","journal-title":"Arch Intern Med"},{"issue":"2","key":"2413_CR8","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1001\/archinte.1993.00410020010002","volume":"153","author":"The fifth report of the Joint National Committee on","year":"1993","unstructured":"The fifth report of the Joint National Committee on. Detection, Evaluation, and Treatment of High Blood Pressure (JNC V). Arch Intern Med. 1993;153(2):154\u201383.","journal-title":"Arch Intern Med"},{"issue":"21","key":"2413_CR9","doi-asserted-by":"publisher","first-page":"2413","DOI":"10.1001\/archinte.1997.00440420033005","volume":"157","author":"The sixth report of the Joint National Committee on","year":"1997","unstructured":"The sixth report of the Joint National Committee on. prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med. 1997;157(21):2413\u201346.","journal-title":"Arch Intern Med"},{"issue":"6","key":"2413_CR10","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","volume":"42","author":"AV Chobanian","year":"2003","unstructured":"Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr., et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42(6):1206\u201352.","journal-title":"Hypertension"},{"issue":"5","key":"2413_CR11","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1001\/jama.2013.284427","volume":"311","author":"PA James","year":"2014","unstructured":"James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311(5):507\u201320.","journal-title":"JAMA"},{"issue":"7","key":"2413_CR12","doi-asserted-by":"publisher","first-page":"499","DOI":"10.7326\/M13-2981","volume":"160","author":"JT Wright Jr","year":"2014","unstructured":"Wright JT Jr., Fine LJ, Lackland DT, Ogedegbe G, Dennison Himmelfarb CR. Evidence supporting a systolic blood pressure goal of less than 150\u00a0mm Hg in patients aged 60 years or older: the minority view. Ann Intern Med. 2014;160(7):499\u2013503.","journal-title":"Ann Intern Med"},{"key":"2413_CR13","doi-asserted-by":"crossref","unstructured":"Whelton PK, Carey RM, Aronow WS, Casey DE Jr., Collins KJ, Dennison Himmelfarb C, et al. ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APhA\/ASH\/ASPC\/NMA\/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension. 2018;71(6):1269\u2009\u2013\u2009324.","DOI":"10.1161\/HYP.0000000000000066"},{"issue":"6","key":"2413_CR14","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1161\/CIRCULATIONAHA.123.067626","volume":"149","author":"SS Khan","year":"2024","unstructured":"Khan SS, Matsushita K, Sang Y, Ballew SH, Grams ME, Surapaneni A, et al. Development and Validation of the American Heart Association\u2019s PREVENT Equations. Circulation. 2024;149(6):430\u201349.","journal-title":"Circulation"},{"issue":"3","key":"2413_CR15","doi-asserted-by":"publisher","first-page":"e00258","DOI":"10.1161\/HYP.0000000000000258","volume":"83","author":"JB King","year":"2026","unstructured":"King JB, An J, Bellows BK, Cohen JB, Commodore-Mensah Y, Ghazi L, et al. Single-Pill Combination Therapy for the Management of Hypertension: A Scientific Statement From the American Heart Association. Hypertension. 2026;83(3):e00258.","journal-title":"Hypertension"},{"issue":"3","key":"2413_CR16","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1161\/CIRCULATIONAHA.125.077650","volume":"153","author":"JB Cohen","year":"2026","unstructured":"Cohen JB, Jones DW, Flack JM. From Race-Based to Equity-Informed Antihypertensive Medication Selection: Rationale for the 2025 AHA\/ACC Guideline Change. Circulation. 2026;153(3):137\u20139.","journal-title":"Circulation"},{"issue":"12","key":"2413_CR17","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1056\/NEJMoa2105675","volume":"385","author":"B Neal","year":"2021","unstructured":"Neal B, Wu Y, Feng X, Zhang R, Zhang Y, Shi J, et al. Effect of Salt Substitution on Cardiovascular Events and Death. N Engl J Med. 2021;385(12):1067\u201377.","journal-title":"N Engl J Med"},{"issue":"12","key":"2413_CR18","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1093\/ajh\/hpac079","volume":"35","author":"A Vaidya","year":"2022","unstructured":"Vaidya A, Hundemer GL, Nanba K, Parksook WW, Brown JM. Primary Aldosteronism: State-of-the-Art Review. Am J Hypertens. 2022;35(12):967\u201388.","journal-title":"Am J Hypertens"},{"issue":"15","key":"2413_CR19","doi-asserted-by":"publisher","first-page":"e036373","DOI":"10.1161\/JAHA.124.036373","volume":"13","author":"W Kositanurit","year":"2024","unstructured":"Kositanurit W, Giacona JM, Xie D, Wang J, Feuer D, O\u2019Malley KJ, et al. Trends in Primary Aldosteronism Screening Among High-Risk Hypertensive Adults. J Am Heart Assoc. 2024;13(15):e036373.","journal-title":"J Am Heart Assoc"},{"issue":"1","key":"2413_CR20","doi-asserted-by":"publisher","first-page":"10","DOI":"10.7326\/M20-0065","volume":"173","author":"JM Brown","year":"2020","unstructured":"Brown JM, Siddiqui M, Calhoun DA, Carey RM, Hopkins PN, Williams GH, et al. The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study. Ann Intern Med. 2020;173(1):10\u201320.","journal-title":"Ann Intern Med"},{"issue":"14","key":"2413_CR21","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1016\/j.jacc.2017.01.052","volume":"69","author":"S Monticone","year":"2017","unstructured":"Monticone S, Burrello J, Tizzani D, Bertello C, Viola A, Buffolo F, et al. Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice. J Am Coll Cardiol. 2017;69(14):1811\u201320.","journal-title":"J Am Coll Cardiol"},{"issue":"10008","key":"2413_CR22","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1016\/S0140-6736(15)00257-3","volume":"386","author":"B Williams","year":"2015","unstructured":"Williams B, MacDonald TM, Morant S, Webb DJ, Sever P, McInnes G, et al. Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial. Lancet. 2015;386(10008):2059\u201368.","journal-title":"Lancet"},{"issue":"10","key":"2413_CR23","doi-asserted-by":"publisher","first-page":"e135","DOI":"10.1161\/HYP.0000000000000240","volume":"81","author":"JL Cluett","year":"2024","unstructured":"Cluett JL, Blazek O, Brown AL, East C, Ferdinand KC, Fisher NDL, et al. Renal Denervation for the Treatment of Hypertension: A Scientific Statement From the American Heart Association. Hypertension. 2024;81(10):e135\u201348.","journal-title":"Hypertension"},{"issue":"8","key":"2413_CR24","doi-asserted-by":"publisher","first-page":"e94","DOI":"10.1161\/HYP.0000000000000238","volume":"81","author":"AP Bress","year":"2024","unstructured":"Bress AP, Anderson TS, Flack JM, Ghazi L, Hall ME, Laffer CL, et al. The Management of Elevated Blood Pressure in the Acute Care Setting: A Scientific Statement From the American Heart Association. Hypertension. 2024;81(8):e94\u2013106.","journal-title":"Hypertension"},{"issue":"24","key":"2413_CR25","doi-asserted-by":"publisher","first-page":"3255","DOI":"10.1001\/jama.1991.03460240051027","volume":"265","author":"Prevention of stroke","year":"1991","unstructured":"Prevention of stroke. by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group. JAMA. 1991;265(24):3255\u201364.","journal-title":"JAMA"},{"issue":"22","key":"2413_CR26","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.1056\/NEJMoa1511939","volume":"373","author":"SR Group","year":"2015","unstructured":"Group SR, Wright JT Jr., Williamson JD, Whelton PK, Snyder JK, Sink KM, et al. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2015;373(22):2103\u201316.","journal-title":"N Engl J Med"},{"issue":"20","key":"2413_CR27","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1056\/NEJMoa1901281","volume":"384","author":"SR Group","year":"2021","unstructured":"Group SR, Lewis CE, Fine LJ, Beddhu S, Cheung AK, Cushman WC, et al. Final Report of a Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2021;384(20):1921\u201330.","journal-title":"N Engl J Med"},{"issue":"17","key":"2413_CR28","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1056\/NEJMoa1001286","volume":"362","author":"AS Group","year":"2010","unstructured":"Group AS, Cushman WC, Evans GW, Byington RP, Goff DC Jr., Grimm RH Jr., et al. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010;362(17):1575\u201385.","journal-title":"N Engl J Med"},{"issue":"12","key":"2413_CR29","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1056\/NEJMoa2412006","volume":"392","author":"Y Bi","year":"2025","unstructured":"Bi Y, Li M, Liu Y, Li T, Lu J, Duan P, et al. Intensive Blood-Pressure Control in Patients with Type 2 Diabetes. N Engl J Med. 2025;392(12):1155\u201367.","journal-title":"N Engl J Med"},{"issue":"14","key":"2413_CR30","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1056\/NEJMoa2111437","volume":"385","author":"W Zhang","year":"2021","unstructured":"Zhang W, Zhang S, Deng Y, Wu S, Ren J, Sun G, et al. Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension. N Engl J Med. 2021;385(14):1268\u201379.","journal-title":"N Engl J Med"},{"issue":"17","key":"2413_CR31","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1016\/j.jacc.2025.06.045","volume":"86","author":"Q Song","year":"2025","unstructured":"Song Q, Peng X, Bai J, Yang R, Ling Q, Chen S, et al. Intensive Blood Pressure Control in Older Patients With Hypertension: 6-Year Results of the STEP Trial. J Am Coll Cardiol. 2025;86(17):1421\u201333.","journal-title":"J Am Coll Cardiol"},{"issue":"10449","key":"2413_CR32","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/S0140-6736(24)01028-6","volume":"404","author":"J Liu","year":"2024","unstructured":"Liu J, Li Y, Ge J, Yan X, Zhang H, Zheng X, et al. Lowering systolic blood pressure to less than 120\u00a0mm Hg versus less than 140\u00a0mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial. Lancet. 2024;404(10449):245\u201355.","journal-title":"Lancet"},{"issue":"10285","key":"2413_CR33","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1016\/S0140-6736(21)00590-0","volume":"397","author":"Blood Pressure Lowering Treatment Trialists C","year":"2021","unstructured":"Blood Pressure Lowering Treatment Trialists C. Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis. Lancet. 2021;397(10285):1625\u201336.","journal-title":"Lancet"},{"issue":"5","key":"2413_CR34","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1161\/HYPERTENSIONAHA.117.10479","volume":"71","author":"KC Johnson","year":"2018","unstructured":"Johnson KC, Whelton PK, Cushman WC, Cutler JA, Evans GW, Snyder JK, et al. Blood Pressure Measurement in SPRINT (Systolic Blood Pressure Intervention Trial). Hypertension. 2018;71(5):848\u201357.","journal-title":"Hypertension"},{"issue":"6","key":"2413_CR35","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1001\/jama.2018.21442","volume":"321","author":"SMISR Group","year":"2019","unstructured":"Group SMISR, Williamson JD, Pajewski NM, Auchus AP, Bryan RN, Chelune G, et al. Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial. JAMA. 2019;321(6):553\u201361.","journal-title":"JAMA"},{"issue":"3","key":"2413_CR36","doi-asserted-by":"publisher","first-page":"e213334","DOI":"10.1212\/WNL.0000000000213334","volume":"104","author":"DM Reboussin","year":"2025","unstructured":"Reboussin DM, Gaussoin SA, Pajewski NM, Jaeger BC, Sachs B, Rapp SR, et al. Long-Term Effect of Intensive vs Standard Blood Pressure Control on Mild Cognitive Impairment and Probable Dementia in SPRINT. Neurology. 2025;104(3):e213334.","journal-title":"Neurology"},{"issue":"6","key":"2413_CR37","doi-asserted-by":"publisher","first-page":"2054","DOI":"10.1038\/s41591-025-03616-8","volume":"31","author":"J He","year":"2025","unstructured":"He J, Zhao C, Zhong S, Ouyang N, Sun G, Qiao L, et al. Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial. Nat Med. 2025;31(6):2054\u201361.","journal-title":"Nat Med"},{"issue":"48","key":"2413_CR38","doi-asserted-by":"publisher","first-page":"4980","DOI":"10.1093\/eurheartj\/ehac584","volume":"43","author":"R Peters","year":"2022","unstructured":"Peters R, Xu Y, Fitzgerald O, Aung HL, Beckett N, Bulpitt C, et al. Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis. Eur Heart J. 2022;43(48):4980\u201390.","journal-title":"Eur Heart J"},{"issue":"19","key":"2413_CR39","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1056\/NEJMoa2201295","volume":"386","author":"AT Tita","year":"2022","unstructured":"Tita AT, Szychowski JM, Boggess K, Dugoff L, Sibai B, Lawrence K, et al. Treatment for Mild Chronic Hypertension during Pregnancy. N Engl J Med. 2022;386(19):1781\u201392.","journal-title":"N Engl J Med"},{"issue":"6","key":"2413_CR40","doi-asserted-by":"publisher","first-page":"e237","DOI":"10.1097\/AOG.0000000000003891","volume":"135","author":"Gestational Hypertension and Preeclampsia","year":"2020","unstructured":"Gestational Hypertension and Preeclampsia. ACOG Practice Bulletin, Number 222. Obstet Gynecol. 2020;135(6):e237\u201360.","journal-title":"Obstet Gynecol"},{"issue":"2","key":"2413_CR41","doi-asserted-by":"crossref","first-page":"B24","DOI":"10.1016\/j.ajog.2022.04.011","volume":"227","author":"Society for Maternal-Fetal Medicine Statement","year":"2022","unstructured":"Society for Maternal-Fetal Medicine Statement. Antihypertensive therapy for mild chronic hypertension in pregnancy\u2013The Chronic Hypertension and Pregnancy trial. Am J Obstet Gynecol. 2022;227(2):B24\u20137.","journal-title":"Am J Obstet Gynecol"},{"issue":"3S","key":"2413_CR42","first-page":"S1","volume":"99","author":"Kidney Disease","year":"2021","unstructured":"Kidney Disease. Improving Global Outcomes Blood Pressure Work G. KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease. Kidney Int. 2021;99(3S):S1\u201387.","journal-title":"Kidney Int"}],"container-title":["Current Cardiology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-026-02413-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11886-026-02413-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11886-026-02413-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T09:25:17Z","timestamp":1788773117000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11886-026-02413-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,7]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2413"],"URL":"https:\/\/doi.org\/10.1007\/s11886-026-02413-0","relation":{},"ISSN":["1534-3170"],"issn-type":[{"value":"1534-3170","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,7]]},"assertion":[{"value":"11 August 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"No artificial intelligence tools were used in the preparation, writing, analysis, or editing of this manuscript.","order":1,"name":"Ethics","label":"Use of Artificial Intelligence","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This article does not contain any studies with human or animal subjects performed by any of the authors.","order":2,"name":"Ethics","label":"Human and Animal Rights and Informed Consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest","order":3,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"90"}}