{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T15:22:08Z","timestamp":1772551328326,"version":"3.50.1"},"reference-count":88,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T00:00:00Z","timestamp":1741305600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T00:00:00Z","timestamp":1741305600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Gastroenterol Rep"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s11894-025-00969-5","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T07:50:41Z","timestamp":1741333841000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Challenges to Optimizing Nutrition in Children With Cystic Fibrosis"],"prefix":"10.1007","volume":"27","author":[{"given":"Charles B.","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill A.","family":"Granneman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanu R.","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,7]]},"reference":[{"issue":"3","key":"969_CR1","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s00408-019-00218-3","volume":"197","author":"M Ashkenazi","year":"2019","unstructured":"Ashkenazi M, Nathan N, Sarouk I, Aluma BEB, Dagan A, Bezalel Y, et al. Nutritional status in childhood as a prognostic factor in patients with cystic fibrosis. Lung. 2019;197(3):371\u20136.","journal-title":"Lung"},{"issue":"6","key":"969_CR2","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1177\/0884533613507086","volume":"28","author":"S Culhane","year":"2013","unstructured":"Culhane S, George C, Pearo B, Spoede E. Malnutrition in cystic fibrosis: a review. Nutr Clin Pract. 2013;28(6):676\u201383.","journal-title":"Nutr Clin Pract"},{"issue":"3","key":"969_CR3","doi-asserted-by":"publisher","first-page":"479","DOI":"10.3390\/nu15030479","volume":"15","author":"E Mariotti Zani","year":"2023","unstructured":"Mariotti Zani E, Grandinetti R, Cunico D, Torelli L, Fainardi V, Pisi G, et al. Nutritional care in children with cystic fibrosis. Nutrients. 2023;15(3):479.","journal-title":"Nutrients"},{"issue":"5","key":"969_CR4","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/j.jcf.2021.12.014","volume":"21","author":"A Madde","year":"2022","unstructured":"Madde A, Okoniewski W, Sanders DB, Ren CL, Weiner DJ, Forno E. Nutritional status and lung function in children with pancreatic-sufficient cystic fibrosis. J Cyst Fibros. 2022;21(5):769\u201376.","journal-title":"J Cyst Fibros"},{"issue":"3","key":"969_CR5","doi-asserted-by":"publisher","first-page":"e220740","DOI":"10.1001\/jamanetworkopen.2022.0740","volume":"5","author":"R Nagy","year":"2022","unstructured":"Nagy R, Gede N, Ocskay K, Dobai BM, Abada A, Vereczkei Z, et al. Association of body mass index with clinical outcomes in patients with cystic fibrosis: A systematic review and Meta-analysis. JAMA Netw Open. 2022;5(3):e220740.","journal-title":"JAMA Netw Open"},{"issue":"9","key":"969_CR6","doi-asserted-by":"publisher","first-page":"2907","DOI":"10.3390\/nu13092907","volume":"13","author":"R Bass","year":"2021","unstructured":"Bass R, Brownell JN, Stallings VA. The impact of highly effective CFTR modulators on growth and nutrition status. Nutrients. 2021;13(9):2907.","journal-title":"Nutrients"},{"issue":"2","key":"969_CR7","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1164\/rccm.201404-0703OC","volume":"190","author":"SM Rowe","year":"2014","unstructured":"Rowe SM, Heltshe SL, Gonska T, Donaldson SH, Borowitz D, Gelfond D, et al. Clinical mechanism of the cystic fibrosis transmembrane conductance regulator potentiator Ivacaftor in G551D-mediated cystic fibrosis. Am J Respir Crit Care Med. 2014;190(2):175\u201384.","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"969_CR8","doi-asserted-by":"publisher","first-page":"e81","DOI":"10.1038\/ctg.2017.10","volume":"8","author":"D Gelfond","year":"2017","unstructured":"Gelfond D, Heltshe S, Ma C, Rowe SM, Frederick C, Uluer A, et al. Impact of CFTR modulation on intestinal pH, motility, and clinical outcomes in patients with cystic fibrosis and the G551D mutation. Clin Transl Gastroenterol. 2017;8(3):e81.","journal-title":"Clin Transl Gastroenterol"},{"issue":"1","key":"969_CR9","doi-asserted-by":"publisher","first-page":"17834","DOI":"10.1038\/s41598-018-36364-6","volume":"8","author":"CY Ooi","year":"2018","unstructured":"Ooi CY, Syed SA, Rossi L, Garg M, Needham B, Avolio J, et al. Impact of CFTR modulation with Ivacaftor on gut microbiota and intestinal inflammation. Sci Rep. 2018;8(1):17834.","journal-title":"Sci Rep"},{"issue":"5","key":"969_CR10","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.3390\/nu14051028","volume":"14","author":"D Patel","year":"2022","unstructured":"Patel D, Shan A, Mathews S, Sathe M. Understanding cystic fibrosis comorbidities and their impact on nutritional management. Nutrients. 2022;14(5):1028.","journal-title":"Nutrients"},{"issue":"6","key":"969_CR11","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1513\/AnnalsATS.201401-044FR","volume":"11","author":"NB Robinson","year":"2014","unstructured":"Robinson NB, DiMango E. Prevalence of gastroesophageal reflux in cystic fibrosis and implications for lung disease. Ann Am Thorac Soc. 2014;11(6):964\u20138.","journal-title":"Ann Am Thorac Soc"},{"issue":"3","key":"969_CR12","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.dld.2022.09.005","volume":"55","author":"L Zazzeron","year":"2023","unstructured":"Zazzeron L, Alicandro G, Dacc\u00f2 V, Lanfranchi C, Bulfamante A, Sciarrabba CS, et al. Effects of prolonged proton pump inhibitor treatment on nutritional status and respiratory infection risk in cystic fibrosis: A matched cohort study. Dig Liver Dis. 2023;55(3):360\u20135.","journal-title":"Dig Liver Dis"},{"issue":"5","key":"969_CR13","doi-asserted-by":"publisher","first-page":"288","DOI":"10.14740\/gr917w","volume":"10","author":"F Ayoub","year":"2017","unstructured":"Ayoub F, Lascano J, Morelli G. Proton pump inhibitor use is associated with an increased frequency of hospitalization in patients with cystic fibrosis. Gastroenterol Res. 2017;10(5):288\u201393.","journal-title":"Gastroenterol Res"},{"issue":"6","key":"969_CR14","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1002\/jpn3.12389","volume":"79","author":"C Liu","year":"2024","unstructured":"Liu C, Bach TR, Farrell PM, Pavelec D, Antos NJ, Rock MJ, et al. Impact of acid blocker therapy on growth, gut microbiome, and lung disease in young children with cystic fibrosis. J Pediatr Gastroenterol Nutr. 2024;79(6):1124\u201333.","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"8","key":"969_CR15","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1016\/j.jpedsurg.2007.03.030","volume":"42","author":"RP Boesch","year":"2007","unstructured":"Boesch RP, Acton JD. Outcomes of fundoplication in children with cystic fibrosis. J Pediatr Surg. 2007;42(8):1341\u20134.","journal-title":"J Pediatr Surg"},{"issue":"4","key":"969_CR16","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.jcf.2021.05.016","volume":"20","author":"S Henen","year":"2021","unstructured":"Henen S, Denton C, Teckman J, Borowitz D, Patel D. Review of Gastrointestinal motility in cystic fibrosis. J Cyst Fibros. 2021;20(4):578\u201385.","journal-title":"J Cyst Fibros"},{"issue":"8","key":"969_CR17","doi-asserted-by":"publisher","first-page":"2275","DOI":"10.1007\/s10620-012-2209-1","volume":"58","author":"D Gelfond","year":"2013","unstructured":"Gelfond D, Ma C, Semler J, Borowitz D. Intestinal pH and Gastrointestinal transit profiles in cystic fibrosis patients measured by wireless motility capsule. Dig Dis Sci. 2013;58(8):2275\u201381.","journal-title":"Dig Dis Sci"},{"issue":"8\u20139","key":"969_CR18","doi-asserted-by":"publisher","first-page":"920","DOI":"10.3109\/00365521.2012.699548","volume":"47","author":"C Hedsund","year":"2012","unstructured":"Hedsund C, Gregersen T, Joensson IM, Olesen HV, Krogh K. Gastrointestinal transit times and motility in patients with cystic fibrosis. Scand J Gastroenterol. 2012;47(8\u20139):920\u20136.","journal-title":"Scand J Gastroenterol"},{"issue":"3","key":"969_CR19","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1177\/0884533614527773","volume":"29","author":"AJ Berry","year":"2014","unstructured":"Berry AJ. Pancreatic enzyme replacement therapy during pancreatic insufficiency. Nutr Clin Pract. 2014;29(3):312\u201321.","journal-title":"Nutr Clin Pract"},{"issue":"Suppl 1","key":"969_CR20","first-page":"S57","volume":"39","author":"CM McDonald","year":"2024","unstructured":"McDonald CM, Reid EK, Pohl JF, Yuzyuk TK, Padula LM, Vavrina K, et al. Cystic fibrosis and fat malabsorption: pathophysiology of the cystic fibrosis Gastrointestinal tract and the impact of highly effective CFTR modulator therapy. Nutr Clin Pract. 2024;39(Suppl 1):S57\u201377.","journal-title":"Nutr Clin Pract"},{"issue":"7","key":"969_CR21","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/S2213-2600(18)30202-9","volume":"6","author":"M Rosenfeld","year":"2018","unstructured":"Rosenfeld M, Wainwright CE, Higgins M, Wang LT, McKee C, Campbell D, et al. Ivacaftor treatment of cystic fibrosis in children aged 12 to <\u200924 months and with a CFTR gating mutation (ARRIVAL): a phase 3 single-arm study. Lancet Respir Med. 2018;6(7):545\u201353.","journal-title":"Lancet Respir Med"},{"key":"969_CR22","doi-asserted-by":"crossref","unstructured":"Stallings VA, Sainath N, Oberle M, Bertolaso C, Schall JI. Energy balance and mechanisms of weight gain with Ivacaftor treatment of cystic fibrosis gating mutations. J Pediatr. 2018;201:229\u2013\u200937.e4.","DOI":"10.1016\/j.jpeds.2018.05.018"},{"issue":"11","key":"969_CR23","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1007\/s00431-003-1309-5","volume":"162","author":"M Proesmans","year":"2003","unstructured":"Proesmans M, De Boeck K. Omeprazole, a proton pump inhibitor, improves residual steatorrhoea in cystic fibrosis patients treated with high dose pancreatic enzymes. Eur J Pediatr. 2003;162(11):760\u20133.","journal-title":"Eur J Pediatr"},{"key":"969_CR24","doi-asserted-by":"crossref","unstructured":"Phillips AE, Brownell JN, Tindall A, Kiernan BD, Patel D, Gelfond D, et al. Proton-pump inhibitors and fat absorption in cystic fibrosis and pancreatic insufficiency: a randomized crossover pilot trial. Dig Dis Sci. 2024.","DOI":"10.1007\/s10620-024-08728-8"},{"issue":"5","key":"969_CR25","doi-asserted-by":"publisher","first-page":"e817","DOI":"10.1542\/peds.2005-1655","volume":"117","author":"RB Canani","year":"2006","unstructured":"Canani RB, Cirillo P, Roggero P, Romano C, Malamisura B, Terrin G, et al. Therapy with gastric acidity inhibitors increases the risk of acute gastroenteritis and community-acquired pneumonia in children. Pediatrics. 2006;117(5):e817\u201320.","journal-title":"Pediatrics"},{"issue":"7","key":"969_CR26","doi-asserted-by":"publisher","first-page":"2048","DOI":"10.1002\/ppul.25431","volume":"56","author":"AH Gifford","year":"2021","unstructured":"Gifford AH, Sanville JL, Sathe M, Heltshe SL, Goss CH. Use of proton pump inhibitors is associated with lower hemoglobin levels in people with cystic fibrosis. Pediatr Pulmonol. 2021;56(7):2048\u201356.","journal-title":"Pediatr Pulmonol"},{"issue":"22","key":"969_CR27","doi-asserted-by":"publisher","first-page":"3400","DOI":"10.3748\/wjg.v29.i22.3400","volume":"29","author":"I Efremova","year":"2023","unstructured":"Efremova I, Maslennikov R, Poluektova E, Vasilieva E, Zharikov Y, Suslov A, et al. Epidemiology of small intestinal bacterial overgrowth. World J Gastroenterol. 2023;29(22):3400\u201321.","journal-title":"World J Gastroenterol"},{"issue":"3","key":"969_CR28","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s00535-018-1509-4","volume":"54","author":"M Furnari","year":"2019","unstructured":"Furnari M, De Alessandri A, Cresta F, Haupt M, Bassi M, Calvi A, et al. The role of small intestinal bacterial overgrowth in cystic fibrosis: a randomized case-controlled clinical trial with rifaximin. J Gastroenterol. 2019;54(3):261\u201370.","journal-title":"J Gastroenterol"},{"issue":"1","key":"969_CR29","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1097\/MPG.0000000000003459","volume":"75","author":"ME Gabel","year":"2022","unstructured":"Gabel ME, Wang H, Gelfond D, Roach C, Rowe SM, Clancy JP, et al. Changes in glucose breath test in cystic fibrosis patients treated with 1 month of Lumacaftor\/Ivacaftor. J Pediatr Gastroenterol Nutr. 2022;75(1):42\u20137.","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"2","key":"969_CR30","doi-asserted-by":"publisher","first-page":"e141","DOI":"10.1016\/j.jcf.2021.09.014","volume":"21","author":"DM Beswick","year":"2022","unstructured":"Beswick DM, Humphries SM, Balkissoon CD, Strand M, Vladar EK, Ramakrishnan VR, et al. Olfactory dysfunction in cystic fibrosis: impact of CFTR modulator therapy. J Cyst Fibros. 2022;21(2):e141\u20137.","journal-title":"J Cyst Fibros"},{"issue":"4","key":"969_CR31","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1016\/j.physbeh.2006.01.029","volume":"87","author":"MR Yeomans","year":"2006","unstructured":"Yeomans MR. Olfactory influences on appetite and satiety in humans. Physiol Behav. 2006;87(4):800\u20134.","journal-title":"Physiol Behav"},{"issue":"1","key":"969_CR32","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1177\/1945892419870450","volume":"34","author":"AM Di Lullo","year":"2020","unstructured":"Di Lullo AM, Iacotucci P, Comegna M, Amato F, Dolce P, Castaldo G, et al. Cystic fibrosis: the sense of smell. Am J Rhinol Allergy. 2020;34(1):35\u201342.","journal-title":"Am J Rhinol Allergy"},{"issue":"9","key":"969_CR33","first-page":"CD008190","volume":"9","author":"D McTavish","year":"2022","unstructured":"McTavish D, Thornton J. Appetite stimulants for people with cystic fibrosis. Cochrane Database Syst Rev. 2022;9(9):CD008190.","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"969_CR34","doi-asserted-by":"publisher","first-page":"155","DOI":"10.2223\/JPED.2174","volume":"88","author":"M Epifanio","year":"2012","unstructured":"Epifanio M, Marostica PC, Mattiello R, Feix L, Nejedlo R, Fischer GB. A randomized, double-blind, placebo-controlled trial of Cyproheptadine for appetite stimulation in cystic fibrosis. J Pediatr (Rio J). 2012;88(2):155\u201360.","journal-title":"J Pediatr (Rio J)"},{"key":"969_CR35","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.clnesp.2021.01.015","volume":"42","author":"J Grunert","year":"2021","unstructured":"Grunert J, van der Haak N, La Vanda C, Farrow N, Tai A. Cyproheptadine as an appetite stimulant in children with cystic fibrosis. Clin Nutr ESPEN. 2021;42:407\u20139.","journal-title":"Clin Nutr ESPEN"},{"key":"969_CR36","doi-asserted-by":"publisher","first-page":"1130790","DOI":"10.3389\/fped.2023.1130790","volume":"11","author":"M Gaschignard","year":"2023","unstructured":"Gaschignard M, Beaufils F, Lussac-Sorton F, Gallet P, Clouzeau H, Menard J, et al. Nutritional impact of CFTR modulators in children with cystic fibrosis. Front Pediatr. 2023;11:1130790.","journal-title":"Front Pediatr"},{"issue":"5","key":"969_CR37","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1002\/ncp.10899","volume":"37","author":"S Sankararaman","year":"2022","unstructured":"Sankararaman S, Hendrix SJ, Schindler T. Update on the management of vitamins and minerals in cystic fibrosis. Nutr Clin Pract. 2022;37(5):1074\u201387.","journal-title":"Nutr Clin Pract"},{"issue":"6","key":"969_CR38","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1016\/j.jcf.2018.03.011","volume":"17","author":"R Sutherland","year":"2018","unstructured":"Sutherland R, Katz T, Liu V, Quintano J, Brunner R, Tong CW, et al. Dietary intake of energy-dense, nutrient-poor and nutrient-dense food sources in children with cystic fibrosis. J Cyst Fibros. 2018;17(6):804\u201310.","journal-title":"J Cyst Fibros"},{"issue":"3","key":"969_CR39","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.jcf.2019.01.002","volume":"18","author":"MP Bellissimo","year":"2019","unstructured":"Bellissimo MP, Zhang I, Ivie EA, Tran PH, Tangpricha V, Hunt WR, et al. Visceral adipose tissue is associated with poor diet quality and higher fasting glucose in adults with cystic fibrosis. J Cyst Fibros. 2019;18(3):430\u20135.","journal-title":"J Cyst Fibros"},{"issue":"6","key":"969_CR40","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1016\/j.jcf.2023.08.004","volume":"22","author":"C Greaney","year":"2023","unstructured":"Greaney C, Doyle A, Drummond N, King S, Hollander-Kraaijeveld F, Robinson K, et al. What do people with cystic fibrosis eat? Diet quality, macronutrient and micronutrient intakes (compared to recommended guidelines) in adults with cystic fibrosis-A systematic review. J Cyst Fibros. 2023;22(6):1036\u201347.","journal-title":"J Cyst Fibros"},{"issue":"7","key":"969_CR41","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1136\/jclinpath-2013-201787","volume":"67","author":"M Rana","year":"2014","unstructured":"Rana M, Wong-See D, Katz T, Gaskin K, Whitehead B, Jaffe A, et al. Fat-soluble vitamin deficiency in children and adolescents with cystic fibrosis. J Clin Pathol. 2014;67(7):605\u20138.","journal-title":"J Clin Pathol"},{"issue":"2","key":"969_CR42","first-page":"252","volume":"10","author":"M Francalanci","year":"2023","unstructured":"Francalanci M, Terlizzi V, Fevola C, Di Rosa G, Pierattini V, Roselli E, et al. Nutritional status and Circulating levels of Fat-Soluble vitamins in cystic fibrosis patients: A cohort study and evaluation of the effect of CFTR modulators. Child (Basel). 2023;10(2):252.","journal-title":"Child (Basel)"},{"issue":"5","key":"969_CR43","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.jcf.2023.04.019","volume":"22","author":"L Schembri","year":"2023","unstructured":"Schembri L, Warraich S, Bentley S, Carr SB, Balfour-Lynn IM. Impact of Elexacaftor\/tezacaftor\/ivacaftor on fat-soluble vitamin levels in children with cystic fibrosis. J Cyst Fibros. 2023;22(5):843\u20136.","journal-title":"J Cyst Fibros"},{"issue":"6","key":"969_CR44","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1016\/j.jcf.2023.08.002","volume":"22","author":"GE Hergenroeder","year":"2023","unstructured":"Hergenroeder GE, Faino A, Bridges G, Bartlett LE, Cogen JD, Green N, et al. The impact of Elexacaftor\/tezacaftor\/ivacaftor on fat-soluble vitamin levels in people with cystic fibrosis. J Cyst Fibros. 2023;22(6):1048\u201353.","journal-title":"J Cyst Fibros"},{"issue":"1","key":"969_CR45","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s40348-024-00178-6","volume":"11","author":"D Fabricius","year":"2024","unstructured":"Fabricius D, Knieling T, Zurmuehl N, Makedon L, Freihorst J, Schmidt H, et al. Changes in vitamins and trace elements after initiation of highly effective CFTR modulator therapy in children and adults with cystic fibrosis - a real-life insight. Mol Cell Pediatr. 2024;11(1):4.","journal-title":"Mol Cell Pediatr"},{"issue":"Suppl 1","key":"969_CR46","first-page":"S27","volume":"34","author":"S Sankararaman","year":"2019","unstructured":"Sankararaman S, Schindler T, Sferra TJ. Management of exocrine pancreatic insufficiency in children. Nutr Clin Pract. 2019;34(Suppl 1):S27\u201342.","journal-title":"Nutr Clin Pract"},{"issue":"5","key":"969_CR47","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1097\/01.mpg.0000234082.47884.d9","volume":"43","author":"JI Schall","year":"2006","unstructured":"Schall JI, Bentley T, Stallings VA. Meal patterns, dietary fat intake and pancreatic enzyme use in preadolescent children with cystic fibrosis. J Pediatr Gastroenterol Nutr. 2006;43(5):651\u20139.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"969_CR48","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.clnesp.2019.06.004","volume":"33","author":"AP Borschuk","year":"2019","unstructured":"Borschuk AP, Filigno SS, Opipari-Arrigan L, Peugh J, Stark LJ. Psychological predictors of nutritional adherence in adolescents with cystic fibrosis. Clin Nutr ESPEN. 2019;33:143\u20137.","journal-title":"Clin Nutr ESPEN"},{"key":"969_CR49","first-page":"117","volume":"7","author":"LC Bishay","year":"2016","unstructured":"Bishay LC, Sawicki GS. Strategies to optimize treatment adherence in adolescent patients with cystic fibrosis. Adolesc Health Med Ther. 2016;7:117\u201324.","journal-title":"Adolesc Health Med Ther"},{"issue":"1","key":"969_CR50","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.jadohealth.2004.09.013","volume":"38","author":"GN Zindani","year":"2006","unstructured":"Zindani GN, Streetman DD, Streetman DS, Nasr SZ. Adherence to treatment in children and adolescent patients with cystic fibrosis. J Adolesc Health. 2006;38(1):13\u20137.","journal-title":"J Adolesc Health"},{"issue":"2","key":"969_CR51","doi-asserted-by":"publisher","first-page":"e20152296","DOI":"10.1542\/peds.2015-2296","volume":"137","author":"DH Barker","year":"2016","unstructured":"Barker DH, Quittner AL. Parental depression and pancreatic enzymes adherence in children with cystic fibrosis. Pediatrics. 2016;137(2):e20152296.","journal-title":"Pediatrics"},{"issue":"2","key":"969_CR52","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1002\/ppul.21164","volume":"45","author":"KK Marciel","year":"2010","unstructured":"Marciel KK, Saiman L, Quittell LM, Dawkins K, Quittner AL. Cell phone intervention to improve adherence: cystic fibrosis care team, patient, and parent perspectives. Pediatr Pulmonol. 2010;45(2):157\u201364.","journal-title":"Pediatr Pulmonol"},{"issue":"4","key":"969_CR53","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.jcf.2020.04.001","volume":"19","author":"M Boon","year":"2020","unstructured":"Boon M, Calvo-Lerma J, Claes I, Havermans T, Asseiceira I, Bulfamante A, et al. Use of a mobile application for self-management of pancreatic enzyme replacement therapy is associated with improved gastro-intestinal related quality of life in children with cystic fibrosis. J Cyst Fibros. 2020;19(4):562\u20138.","journal-title":"J Cyst Fibros"},{"issue":"2","key":"969_CR54","doi-asserted-by":"publisher","first-page":"e11080","DOI":"10.2196\/11080","volume":"1","author":"M Longacre","year":"2018","unstructured":"Longacre M, Grande S, Hager A, Montan M, Bergquist RP, Martensson M, et al. Clinical adoption of mHealth technology to support pediatric cystic fibrosis care in Sweden: qualitative case study. JMIR Pediatr Parent. 2018;1(2):e11080.","journal-title":"JMIR Pediatr Parent"},{"issue":"12","key":"969_CR55","doi-asserted-by":"publisher","first-page":"e076539","DOI":"10.1136\/bmjopen-2023-076539","volume":"13","author":"E Zientek","year":"2023","unstructured":"Zientek E, Rane S, Godfrey C, Sisson A, Dickinson KM. Factors guiding gastrostomy tube decision-making for caregivers of children with cystic fibrosis: a scoping review protocol. BMJ Open. 2023;13(12):e076539.","journal-title":"BMJ Open"},{"issue":"3","key":"969_CR56","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.jpeds.2012.08.040","volume":"162","author":"EH Yen","year":"2013","unstructured":"Yen EH, Quinton H, Borowitz D. Better nutritional status in early childhood is associated with improved clinical outcomes and survival in patients with cystic fibrosis. J Pediatr. 2013;162(3):530\u2013e51.","journal-title":"J Pediatr"},{"issue":"6","key":"969_CR57","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.jcf.2016.08.004","volume":"15","author":"SJ Schwarzenberg","year":"2016","unstructured":"Schwarzenberg SJ, Hempstead SE, McDonald CM, Powers SW, Wooldridge J, Blair S, et al. Enteral tube feeding for individuals with cystic fibrosis: cystic fibrosis foundation evidence-informed guidelines. J Cyst Fibros. 2016;15(6):724\u201335.","journal-title":"J Cyst Fibros"},{"issue":"Suppl 2","key":"969_CR58","doi-asserted-by":"publisher","first-page":"S87","DOI":"10.1016\/j.jcf.2017.07.010","volume":"16","author":"JS Sullivan","year":"2017","unstructured":"Sullivan JS, Mascarenhas MR, Nutrition. Prevention and management of nutritional failure in cystic fibrosis. J Cyst Fibros. 2017;16(Suppl 2):S87\u201393.","journal-title":"J Cyst Fibros"},{"issue":"12 Suppl","key":"969_CR59","first-page":"S220","volume":"23","author":"S Freedman","year":"2017","unstructured":"Freedman S. Options for addressing exocrine pancreatic insufficiency in patients receiving enteral nutrition supplementation. Am J Manag Care. 2017;23(12 Suppl):S220\u20138.","journal-title":"Am J Manag Care"},{"issue":"4","key":"969_CR60","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1097\/MPG.0000000000002110","volume":"67","author":"J Stevens","year":"2018","unstructured":"Stevens J, Wyatt C, Brown P, Patel D, Grujic D, Freedman SD. Absorption and safety with sustained use of relizorb evaluation (ASSURE) study in patients with cystic fibrosis receiving enteral feeding. J Pediatr Gastroenterol Nutr. 2018;67(4):527\u201332.","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"4","key":"969_CR61","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1002\/ncp.11142","volume":"39","author":"S Shrivastava","year":"2024","unstructured":"Shrivastava S, Shaw K, Lee M, Reitich P, Hunter S, Klosterman M, et al. Association of in-line digestive enzyme cartridge with enteral feeds on improvement in anthropometrics among pediatric patients with cystic fibrosis. Nutr Clin Pract. 2024;39(4):903\u201310.","journal-title":"Nutr Clin Pract"},{"issue":"2","key":"969_CR62","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1002\/ncp.10831","volume":"37","author":"SJ Hendrix","year":"2022","unstructured":"Hendrix SJ, Flume PA, First ER, Stone AA, Van Buskirk M. Improvements in anthropometric measures and Gastrointestinal tolerance in patients with cystic fibrosis by using a digestive enzyme cartridge with overnight enteral nutrition. Nutr Clin Pract. 2022;37(2):344\u201350.","journal-title":"Nutr Clin Pract"},{"key":"969_CR63","first-page":"325","volume":"1","author":"C McDonald","year":"2009","unstructured":"McDonald C, Christensen N, Lingard C, Peet K, Walker S. Nutrition knowledge and confidence levels of parents of children with cystic fibrosis. ICAN. 2009;1:325\u201331.","journal-title":"ICAN"},{"issue":"13","key":"969_CR64","doi-asserted-by":"publisher","first-page":"2573","DOI":"10.3390\/nu14132573","volume":"14","author":"MA Corbera-Hincapie","year":"2022","unstructured":"Corbera-Hincapie MA, Atteih SE, Stransky OM, Weiner DJ, Yann IM, Kazmerski TM. Experiences and perspectives of individuals with cystic fibrosis and their families related to food insecurity. Nutrients. 2022;14(13):2573.","journal-title":"Nutrients"},{"issue":"2","key":"969_CR65","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1007\/BF00286641","volume":"65","author":"KW Klinger","year":"1983","unstructured":"Klinger KW. Cystic fibrosis in the Ohio Amish: gene frequency and founder effect. Hum Genet. 1983;65(2):94\u20138.","journal-title":"Hum Genet"},{"key":"969_CR66","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1471-2431-9-4","volume":"9","author":"JF Henderson","year":"2009","unstructured":"Henderson JF, Anbar RD. Care for Amish and mennonite children with cystic fibrosis: a case series. BMC Pediatr. 2009;9:4.","journal-title":"BMC Pediatr"},{"key":"969_CR67","first-page":"100280","volume":"26","author":"A Darukhanavala","year":"2021","unstructured":"Darukhanavala A, Merjaneh L, Mason K, Le T. Eating disorders and body image in cystic fibrosis. J Clin Transl Endocrinol. 2021;26:100280.","journal-title":"J Clin Transl Endocrinol"},{"issue":"3","key":"969_CR68","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1006\/jado.2000.0321","volume":"23","author":"NC Raymond","year":"2000","unstructured":"Raymond NC, Chang PN, Crow SJ, Mitchell JE, Dieperink BS, Beck MM, et al. Eating disorders in patients with cystic fibrosis. J Adolesc. 2000;23(3):359\u201363.","journal-title":"J Adolesc"},{"issue":"6","key":"969_CR69","first-page":"915","volume":"9","author":"A Petropoulou","year":"2022","unstructured":"Petropoulou A, Bakounaki G, Grammatikopoulou MG, Bogdanos DP, Goulis DG, Vassilakou T. Eating disorders and disordered eating behaviors in cystic fibrosis: A neglected issue. Child (Basel). 2022;9(6):915.","journal-title":"Child (Basel)"},{"issue":"Suppl 44","key":"969_CR70","first-page":"36","volume":"97","author":"JE Shearer","year":"2004","unstructured":"Shearer JE, Bryon M. The nature and prevalence of eating disorders and eating disturbance in adolescents with cystic fibrosis. J R Soc Med. 2004;97(Suppl 44):36\u201342.","journal-title":"J R Soc Med"},{"issue":"5","key":"969_CR71","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/j.jcf.2023.06.003","volume":"22","author":"JK Tran","year":"2023","unstructured":"Tran JK, Ooi CY, Blazek K, Katz T. Body composition and body mass index measures from 8 to 18 years old in children with cystic fibrosis. J Cyst Fibros. 2023;22(5):851\u20136.","journal-title":"J Cyst Fibros"},{"issue":"5","key":"969_CR72","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/j.jcf.2022.03.010","volume":"21","author":"S Szentpetery","year":"2022","unstructured":"Szentpetery S, Fernandez GS, Schechter MS, Jain R, Flume PA, Fink AK. Obesity in cystic fibrosis: prevalence, trends and associated factors data from the US cystic fibrosis foundation patient registry. J Cyst Fibros. 2022;21(5):777\u201383.","journal-title":"J Cyst Fibros"},{"key":"969_CR73","first-page":"100276","volume":"26","author":"KA Kutney","year":"2021","unstructured":"Kutney KA, Sandouk Z, Desimone M, Moheet A. Obesity in cystic fibrosis. J Clin Transl Endocrinol. 2021;26:100276.","journal-title":"J Clin Transl Endocrinol"},{"issue":"3","key":"969_CR74","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.jcf.2022.11.006","volume":"22","author":"AP Kass","year":"2023","unstructured":"Kass AP, Kazmerski TM, Bern E, Sabharwal S, Leonard J, Harrison M, et al. Clinician perspectives on assessing for disordered eating and body image disturbance in adolescents and young adults with cystic fibrosis. J Cyst Fibros. 2023;22(3):431\u20135.","journal-title":"J Cyst Fibros"},{"issue":"5","key":"969_CR75","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1111\/j.1440-1754.1991.tb02540.x","volume":"27","author":"MR Sanders","year":"1991","unstructured":"Sanders MR, Gravestock FM, Wanstall K, Dunne M. The relationship between children\u2019s treatment-related behaviour problems, age and clinical status in cystic fibrosis. J Paediatr Child Health. 1991;27(5):290\u20134.","journal-title":"J Paediatr Child Health"},{"key":"969_CR76","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.appet.2015.11.020","volume":"97","author":"JM Ellis","year":"2016","unstructured":"Ellis JM, Galloway AT, Webb RM, Martz DM, Farrow CV. Recollections of pressure to eat during childhood, but not picky eating, predict young adult eating behavior. Appetite. 2016;97:58\u201363.","journal-title":"Appetite"},{"issue":"1","key":"969_CR77","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1093\/jpepsy\/jsad076","volume":"49","author":"G Maliszewski","year":"2024","unstructured":"Maliszewski G, High R, Lee J, Deschamp A. Parental feeding style, parenting stress, and child mealtime behaviors in cystic fibrosis. J Pediatr Psychol. 2024;49(1):56\u201365.","journal-title":"J Pediatr Psychol"},{"issue":"3","key":"969_CR78","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.jcf.2005.05.015","volume":"4","author":"SW Powers","year":"2005","unstructured":"Powers SW, Mitchell MJ, Patton SR, Byars KC, Jelalian E, Mulvihill MM, et al. Mealtime behaviors in families of infants and toddlers with cystic fibrosis. J Cyst Fibros. 2005;4(3):175\u201382.","journal-title":"J Cyst Fibros"},{"issue":"6","key":"969_CR79","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1023\/A:1005532602084","volume":"23","author":"J Abbott","year":"2000","unstructured":"Abbott J, Conway S, Etherington C, Fitzjohn J, Gee L, Morton A, et al. Perceived body image and eating behavior in young adults with cystic fibrosis and their healthy peers. J Behav Med. 2000;23(6):501\u201317.","journal-title":"J Behav Med"},{"issue":"6","key":"969_CR80","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1007\/s12529-022-10057-x","volume":"29","author":"H Egan","year":"2022","unstructured":"Egan H, Keyte R, Mantzios M. The challenges of eating well for people living with cystic fibrosis: an interview study exploring the use of mindful eating approaches and behaviours to support optimal nutritional status. Int J Behav Med. 2022;29(6):762\u201374.","journal-title":"Int J Behav Med"},{"key":"969_CR81","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1146\/annurev-clinpsy-021815-093317","volume":"12","author":"E Stice","year":"2016","unstructured":"Stice E. Interactive and mediational etiologic models of eating disorder onset: evidence from prospective studies. Annu Rev Clin Psychol. 2016;12:359\u201381.","journal-title":"Annu Rev Clin Psychol"},{"issue":"3","key":"969_CR82","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.3390\/ijerph18031140","volume":"18","author":"G Tort-Nasarre","year":"2021","unstructured":"Tort-Nasarre G, Pollina Pocallet M, Artigues-Barber\u00e0 E. The meaning and factors that influence the concept of body image: systematic review and Meta-Ethnography from the perspectives of adolescents. Int J Environ Res Public Health. 2021;18(3):1140.","journal-title":"Int J Environ Res Public Health"},{"issue":"2","key":"969_CR83","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.bodyim.2012.10.008","volume":"10","author":"M Pinquart","year":"2013","unstructured":"Pinquart M. Body image of children and adolescents with chronic illness: a meta-analytic comparison with healthy peers. Body Image. 2013;10(2):141\u20138.","journal-title":"Body Image"},{"issue":"1","key":"969_CR84","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.bodyim.2011.09.001","volume":"9","author":"S Tierney","year":"2012","unstructured":"Tierney S. Body image and cystic fibrosis: a critical review. Body Image. 2012;9(1):12\u20139.","journal-title":"Body Image"},{"key":"969_CR85","doi-asserted-by":"publisher","first-page":"101678","DOI":"10.1016\/j.bodyim.2023.101678","volume":"48","author":"JA Levinson","year":"2024","unstructured":"Levinson JA, Kinkel-Ram S, Myers B, Hunger JM. A systematic review of weight stigma and disordered eating cognitions and behaviors. Body Image. 2024;48:101678.","journal-title":"Body Image"},{"issue":"Suppl 1","key":"969_CR86","first-page":"S36","volume":"59","author":"ER Lyons","year":"2024","unstructured":"Lyons ER, Muther E, Sabharwal S. Nutrition and behavioral health in cystic fibrosis: eating and body image. Pediatr Pulmonol. 2024;59(Suppl 1):S36\u201343.","journal-title":"Pediatr Pulmonol"},{"issue":"9","key":"969_CR87","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1093\/jpepsy\/jsx055","volume":"42","author":"SW Helms","year":"2017","unstructured":"Helms SW, Christon LM, Dellon EP, Prinstein MJ. Patient and provider perspectives on communication about body image with adolescents and young adults with cystic fibrosis. J Pediatr Psychol. 2017;42(9):1040\u201350.","journal-title":"J Pediatr Psychol"},{"issue":"5","key":"969_CR88","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1016\/j.jcf.2023.03.011","volume":"22","author":"JE Snowball","year":"2023","unstructured":"Snowball JE, Flight WG, Heath L, Koutoukidis DA. A paradigm shift in cystic fibrosis nutritional care: clinicians\u2019 views on the management of patients with overweight and obesity. J Cyst Fibros. 2023;22(5):836\u201342.","journal-title":"J Cyst Fibros"}],"container-title":["Current Gastroenterology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11894-025-00969-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11894-025-00969-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11894-025-00969-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T12:02:15Z","timestamp":1772539335000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11894-025-00969-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,7]]},"references-count":88,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["969"],"URL":"https:\/\/doi.org\/10.1007\/s11894-025-00969-5","relation":{},"ISSN":["1522-8037","1534-312X"],"issn-type":[{"value":"1522-8037","type":"print"},{"value":"1534-312X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,7]]},"assertion":[{"value":"25 February 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"20"}}