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In CD, the\n                      <jats:italic>NOD2<\/jats:italic>\n                      gene on chromosome 16 and several additional risk variants identified through genome-wide association studies (GWAS)\u2014with key insights from the International Inflammatory Bowel Disease Genetics Consortium\u2014have enhanced our understanding of the pathobiology of the disease. In NSAID enteropathy, polymorphisms in CYP enzymes have been associated with altered drug metabolism and gastrointestinal complications. However, the genetic mechanisms underlying deep ulcers in NSAID enteropathy, as well as CMUSE\/CNSU, remain poorly understood.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Genetic insights are crucial for understanding SB ulcerative diseases. Future research should focus on identifying specific genetic determinants to improve diagnostic accuracy and therapeutic strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11894-025-00978-4","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T18:05:03Z","timestamp":1747850703000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Genetic Mutations and Small Bowel Ulcerating Disease: Role in Diagnosis?"],"prefix":"10.1007","volume":"27","author":[{"given":"Rangesh","family":"Modi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanner","family":"Storozuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Namrata","family":"Setia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"978_CR1","doi-asserted-by":"publisher","first-page":"5374780","DOI":"10.1155\/2022\/5374780","volume":"2022","author":"M Niu","year":"2022","unstructured":"Niu M, Chen ZH, Li M, Zhang X, Chen CX. 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