{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:40:38Z","timestamp":1792442438276,"version":"4.5.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Heart Fail Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose of Review<\/jats:title>\n                    <jats:p>Implanted pulmonary artery pressure (PAP) monitoring provides an early window on imminent worsening heart failure (HF). Randomized trials demonstrated that PAP-guided management significantly reduces HF hospitalizations, but substantial residual risk persists despite recent major advances in HF pharmacotherapy. We review lessons from PAP-guided remote patient management and examine how artificial intelligence (AI) could support more individualized eligibility assessment and multimodal longitudinal surveillance within a patient-centered adaptive care cycle to further improve clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Findings<\/jats:title>\n                    <jats:p>HF is increasingly recognized as a systemic disease characterized, across HF phenotypes, by multiple cardiac and non-cardiac comorbidities. CHAMPION, GUIDE-HF, and MONITOR-HF did not systematically incorporate comorbidity-related risk into patient selection, while PAP-guided treatment focused predominantly on diuretic adjustment, and monitoring strategies were not adapted to individual disease trajectories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>AI could help integrate multidimensional phenotyping to estimate individual risk and expected benefit pre-implant, use comprehensive longitudinal monitoring data to support personalized, actionable clinical decision-making, and enable dynamic adaptation of monitoring intensity tailored to the disease trajectory. This may improve clinical outcomes, reduce healthcare professional workload, enhance patient experience and treatment adherence, and increase cost-effectiveness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11897-026-00783-8","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:10:39Z","timestamp":1792393839000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Personalized Remote Patient Management in Heart Failure"],"prefix":"10.1007","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7491-7637","authenticated-orcid":false,"given":"Christiane E.","family":"Angermann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1692-8669","authenticated-orcid":false,"given":"Folkert W.","family":"Asselbergs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4578-5713","authenticated-orcid":false,"given":"Georg","family":"Ertl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1771-7249","authenticated-orcid":false,"given":"Stefan","family":"St\u00f6rk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"key":"783_CR1","doi-asserted-by":"publisher","first-page":"1644","DOI":"10.1002\/ejhf.3619","volume":"27","author":"A Bayes-Genis","year":"2025","unstructured":"Bayes-Genis A, Pagnesi M, Codina P, Abraham WT, Amir O, de Boer RA, et al. Remote pulmonary artery pressure-guided management of patients with heart failure: a clinical consensus statement of the Heart Failure Association of the ESC. Eur J Heart Fail. 2025;27:1644\u201357.","journal-title":"Eur J Heart Fail"},{"key":"783_CR2","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/S0140-6736(11)60101-3","volume":"377","author":"WT Abraham","year":"2011","unstructured":"Abraham WT, Adamson PB, Bourge RC, Aaron MF, Costanzo MR, Stevenson LW, et al. Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial. Lancet. 2011;377:658\u201366.","journal-title":"Lancet"},{"key":"783_CR3","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/S0140-6736(15)00723-0","volume":"387","author":"WT Abraham","year":"2016","unstructured":"Abraham WT, Stevenson LW, Bourge RC, Lindenfeld JA, Bauman JG, Adamson PB. Sustained efficacy of pulmonary artery pressure to guide adjustment of chronic heart failure therapy: complete follow-up results from the CHAMPION randomised trial. Lancet. 2016;387:453\u201361.","journal-title":"Lancet"},{"key":"783_CR4","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/S0140-6736(21)01754-2","volume":"398","author":"J Lindenfeld","year":"2021","unstructured":"Lindenfeld J, Zile MR, Desai AS, Bhatt K, Ducharme A, Horstmanshof D, et al. Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial. Lancet. 2021;398:991\u20131001.","journal-title":"Lancet"},{"key":"783_CR5","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1016\/S0140-6736(23)00923-6","volume":"401","author":"JJ Brugts","year":"2023","unstructured":"Brugts JJ, Radhoe SP, Clephas PRD, Aydin D, van Gent MWF, Szymanski MK, et al. Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet. 2023;401:2113\u201323.","journal-title":"Lancet"},{"key":"783_CR6","unstructured":"Zorginstituut Nederland. Arteria Pulmonalis (PA) telemonitoring bij pati\u00ebnten met chronisch hartfalen kan worden vergoed uit basispakket. 14 May 2024."},{"key":"783_CR7","unstructured":"Gemeinsamer Bundesausschuss. Drucksensorimplantation und Monitoring des pulmonalarteriellen Druckes bei Herzinsuffizienz im Stadium NYHA III: Einleitung des Stellungnahmeverfahrens. Beschluss vom 23. Juli 2026."},{"key":"783_CR8","doi-asserted-by":"publisher","first-page":"3658","DOI":"10.1093\/eurheartj\/ehad346","volume":"44","author":"PRD Clephas","year":"2023","unstructured":"Clephas PRD, Radhoe SP, Boersma E, Gregson J, Jhund PS, Abraham WT, et al. Efficacy of pulmonary artery pressure monitoring in patients with chronic heart failure: a meta-analysis of three randomized controlled trials. Eur Heart J. 2023;44:3658\u201368.","journal-title":"Eur Heart J"},{"key":"783_CR9","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.jacc.2023.11.030","volume":"83","author":"J Lindenfeld","year":"2024","unstructured":"Lindenfeld J, Costanzo MR, Zile MR, Ducharme A, Troughton R, Maisel A, et al. Implantable hemodynamic monitors improve survival in patients with heart failure and reduced ejection fraction. J Am Coll Cardiol. 2024;83:682\u201394.","journal-title":"J Am Coll Cardiol"},{"key":"783_CR10","doi-asserted-by":"publisher","unstructured":"K\u00f8ber L, Adamo M, et al. 2026 ESC Guidelines for the management of heart failure: Developed by the task force for the management of heart failure of the European Society of Cardiology (ESC). Eur Heart J. 2026. https:\/\/doi.org\/10.1093\/eurheartj\/ehag100.","DOI":"10.1093\/eurheartj\/ehag100"},{"key":"783_CR11","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.jchf.2015.11.011","volume":"4","author":"MR Costanzo","year":"2016","unstructured":"Costanzo MR, Stevenson LW, Adamson PB, Desai AS, Heywood JT, Bourge RC, et al. Interventions linked to decreased heart failure hospitalizations during ambulatory pulmonary artery pressure monitoring. JACC Heart Fail. 2016;4:333\u201344. https:\/\/doi.org\/10.1016\/j.jchf.2015.11.011.","journal-title":"JACC Heart Fail"},{"key":"783_CR12","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.1016\/j.jacc.2017.08.010","volume":"70","author":"MM Givertz","year":"2017","unstructured":"Givertz MM, Stevenson LW, Costanzo MR, Bourge RC, Bauman JG, Ginn G, et al. Pulmonary artery pressure-guided management of patients with heart failure and reduced ejection fraction. J Am Coll Cardiol. 2017;70:1875\u201386. https:\/\/doi.org\/10.1016\/j.jacc.2017.08.010.","journal-title":"J Am Coll Cardiol"},{"key":"783_CR13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.124.012754","volume":"18","author":"MR Zile","year":"2025","unstructured":"Zile MR, Abraham WT, Stevenson LW, Costanzo MR, Angermann CE, Mehra MR, et al. Relationship between remote, ambulatory pulmonary artery pressures, and all-cause mortality in patients with chronic heart failure. Circ Heart Fail. 2025;18. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.124.012754.","journal-title":"Circ Heart Fail"},{"key":"783_CR14","doi-asserted-by":"publisher","unstructured":"Zile MR, Abraham WT, Stevenson LW, Costanzo MR, Angermann CE, Mehra MR, et al. Relationship between ambulatory pulmonary artery pressures and heart failure hospitalizations in patients with chronic heart failure. JACC Heart Fail. 2026;103239. https:\/\/doi.org\/10.1016\/j.jchf.2026.103239","DOI":"10.1016\/j.jchf.2026.10323"},{"key":"783_CR15","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/S0140-6736(14)61176-4","volume":"384","author":"G Hindricks","year":"2014","unstructured":"Hindricks G, Taborsky M, Glikson M, Heinrich U, Schumacher B, Katz A, et al. Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled trial. Lancet. 2014;384:583\u201390. https:\/\/doi.org\/10.1016\/S0140-6736(14)61176-4.","journal-title":"Lancet"},{"key":"783_CR16","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1093\/ehjqcco\/qcy031","volume":"5","author":"D Husser","year":"2019","unstructured":"Husser D, Geller JC, Taborsky M, Schomburg R, Bode F, Nielsen JC, et al. Remote monitoring and clinical outcomes: details on information flow and workflow in the IN-TIME study. Eur Heart J. 2019;5:136\u201344. https:\/\/doi.org\/10.1093\/ehjqcco\/qcy031.","journal-title":"Eur Heart J"},{"key":"783_CR17","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/s11897-022-00548-z","volume":"19","author":"KCC McBeath","year":"2022","unstructured":"McBeath KCC, Angermann CE, Cowie MR. Digital technologies to support better outcome and experience of care in patients with heart failure. Curr Heart Fail Rep. 2022;19:75\u2013108. https:\/\/doi.org\/10.1007\/s11897-022-00548-z.","journal-title":"Curr Heart Fail Rep"},{"key":"783_CR18","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s11897-022-00547-0","volume":"19","author":"MR Cowie","year":"2022","unstructured":"Cowie MR, McBeath KCC, Angermann CE. The digital future of heart failure care. Curr Heart Fail Rep. 2022;19:109\u201313. https:\/\/doi.org\/10.1007\/s11897-022-00547-0.","journal-title":"Curr Heart Fail Rep"},{"key":"783_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-026-02514-8","volume":"9","author":"HL Goh","year":"2026","unstructured":"Goh HL, Sancenon V, Chu BMX, Koh GCH, Koh L, Teo D, et al. Personalised health plan development using agentic AI in Singapore\u2019s national preventive care programme: a pilot study. npj Digit Med. 2026;9. https:\/\/doi.org\/10.1038\/s41746-026-02514-8.","journal-title":"npj Digit Med"},{"key":"783_CR20","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41569-025-01184-5","volume":"23","author":"SM Narayan","year":"2026","unstructured":"Narayan SM, Chung MK, Adedinsewo D, Brant LCC, Davis LL, Duncker D, et al. Access to digital health technologies: personalized framework and global perspectives. Nat Rev Cardiol. 2026;23:9\u201322. https:\/\/doi.org\/10.1038\/s41569-025-01184-5.","journal-title":"Nat Rev Cardiol"},{"key":"783_CR21","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1007\/s00392-022-01987-3","volume":"111","author":"S St\u00f6rk","year":"2022","unstructured":"St\u00f6rk S, Bernhardt A, B\u00f6hm M, Brachmann J, Dagres N, Frantz S, et al. Pulmonary artery sensor system pressure monitoring to improve heart failure outcomes (PASSPORT-HF): rationale and design of the PASSPORT-HF multicenter randomized clinical trial. Clin Res Cardiol. 2022;111:1245\u201355. https:\/\/doi.org\/10.1007\/s00392-022-01987-3.","journal-title":"Clin Res Cardiol"}],"container-title":["Current Heart Failure Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11897-026-00783-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11897-026-00783-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11897-026-00783-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:04:24Z","timestamp":1792440264000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11897-026-00783-8"}},"subtitle":["From Implanted Hemodynamic Monitoring Toward an Artificial Intelligence-Supported Adaptive Care Cycle"],"short-title":[],"issued":{"date-parts":[[2026,10,19]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["783"],"URL":"https:\/\/doi.org\/10.1007\/s11897-026-00783-8","relation":{},"ISSN":["1546-9549"],"issn-type":[{"value":"1546-9549","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,19]]},"assertion":[{"value":"18 September 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article does not contain any studies with human or animal subjects performed by any of the authors.","order":1,"name":"Ethics","label":"Human and Animal Rights and Informed Consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"C.E.A. reports grant support, personal honoraria and\/or non-financial support from Abbott, AstraZeneca, Boehringer Ingelheim and Eli Lilly, Medtronic, Novo Nordisk, Novartis, ResMed, Thermo Fisher Scientific, and Vifor, all outside the submitted work. F.W.A. reports no conflicts of interest. G.E. reports personal fees and\/or grant support from Abbott, Bayer, Boehringer Ingelheim and Eli Lilly, Novartis, ResMed, and Vifor, all outside the submitted work. S.S. reports grant support from the Federal Joint Committee (G-BA; Gemeinsamer Bundesausschuss) related to the PASSPORT-HF trial and from the German Federal Ministry of Education and Research, outside the submitted work, and has received personal honoraria from AstraZeneca, Bayer, Boehringer Ingelheim, Novo Nordisk, all outside the submitted work.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"49"}}