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Approaches to measure telomere length (TL) differ on whether they estimate average, distribution, or chromosome-specific TL, and each presents their own advantages and limitations.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Recent Findings<\/jats:title>\n                <jats:p>The development of long-read sequencing and publication of the telomere-to-telomere human genome reference has allowed for scalable and high-resolution TL estimation in pre-existing sequencing datasets but is still impractical as a dedicated TL test. As sequencing costs continue to fall and strategies for selectively enriching telomere regions prior to sequencing improve, these approaches may become a promising alternative to classic methods.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Summary<\/jats:title>\n                <jats:p>Measurement methods rely on probe hybridization, qPCR or more recently, computational methods using sequencing data. Refinements of existing techniques and new approaches have been recently developed but a test that is accurate, simple, and scalable is still lacking.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11899-023-00717-4","type":"journal-article","created":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T12:01:44Z","timestamp":1699617704000},"page":"284-291","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Experimental and Computational Approaches to Measure Telomere Length: Recent Advances and Future Directions"],"prefix":"10.1007","volume":"18","author":[{"given":"Alejandro","family":"Ferrer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary D.","family":"Stephens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre A.","family":"Kocher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,10]]},"reference":[{"issue":"1","key":"717_CR1","doi-asserted-by":"publisher","first-page":"73","DOI":"10.3390\/cells8010073","volume":"8","author":"KJ Turner","year":"2019","unstructured":"Turner KJ, Vasu V, Griffin DK. 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