{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T15:59:26Z","timestamp":1770134366543,"version":"3.49.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,1,16]],"date-time":"2010-01-16T00:00:00Z","timestamp":1263600000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Science Inc"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1007\/s11906-009-0078-6","type":"journal-article","created":{"date-parts":[[2010,1,15]],"date-time":"2010-01-15T14:01:20Z","timestamp":1263564080000},"page":"39-46","source":"Crossref","is-referenced-by-count":36,"title":["Renal Sympathetic Nerve Ablation: The New Frontier in the Treatment of Hypertension"],"prefix":"10.1007","volume":"12","author":[{"given":"Markus P.","family":"Schlaich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry","family":"Krum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.","family":"Sobotka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,1,16]]},"reference":[{"issue":"6","key":"78_CR1","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1161\/HYPERTENSIONAHA.107.095497","volume":"50","author":"V Perkovic","year":"2007","unstructured":"Perkovic V, Huxley R, Wu Y, et al.: The burden of blood pressure-related disease: a neglected priority for global health. Hypertension 2007, 50(6):991\u2013997.","journal-title":"Hypertension"},{"issue":"9455","key":"78_CR2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0140-6736(05)17741-1","volume":"365","author":"PM Kearney","year":"2005","unstructured":"Kearney PM, Whelton M, Reynolds K, et al.: Global burden of hypertension: analysis of worldwide data. Lancet 2005, 365(9455):217\u2013223.","journal-title":"Lancet"},{"issue":"2","key":"78_CR3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1161\/01.HYP.0000113047.47711.fa","volume":"43","author":"GF DiBona","year":"2004","unstructured":"DiBona GF: The sympathetic nervous system and hypertension: recent developments. Hypertension 2004, 43(2):147\u2013150.","journal-title":"Hypertension"},{"issue":"1","key":"78_CR4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1152\/physrev.1997.77.1.75","volume":"77","author":"GF DiBona","year":"1997","unstructured":"DiBona GF, Kopp UC: Neural control of renal function. Physiol Rev 1997, 77(1):75\u2013197.","journal-title":"Physiol Rev"},{"issue":"4","key":"78_CR5","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1161\/01.HYP.0000153319.20340.2a","volume":"45","author":"BT Alexander","year":"2005","unstructured":"Alexander BT, Hendon AE, Ferril G, Dwyer TM: Renal denervation abolishes hypertension in low-birth-weight offspring from pregnant rats with reduced uterine perfusion. Hypertension 2005, 45(4):754\u2013758.","journal-title":"Hypertension"},{"issue":"4 Pt 2","key":"78_CR6","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1161\/01.HYP.25.4.893","volume":"25","author":"S Kassab","year":"1995","unstructured":"Kassab S, Kato T, Wilkins FC, et al.: Renal denervation attenuates the sodium retention and hypertension associated with obesity. Hypertension 1995, 25(4 Pt 2):893\u2013897.","journal-title":"Hypertension"},{"issue":"16","key":"78_CR7","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1001\/jama.1953.03690160001001","volume":"152","author":"RH Smithwick","year":"1953","unstructured":"Smithwick RH, Thompson JE: Splanchnicectomy for essential hypertension; results in 1,266 cases. J Am Med Assoc 1953, 152(16):1501\u20131504.","journal-title":"J Am Med Assoc"},{"issue":"6757","key":"78_CR8","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0140-6736(53)91589-X","volume":"1","author":"DM Morrissey","year":"1953","unstructured":"Morrissey DM, Brookes VS, Cooke WT: Sympathectomy in the treatment of hypertension, review of 122 cases. Lancet 1953, 1(6757):403\u2013408.","journal-title":"Lancet"},{"issue":"Suppl 5","key":"78_CR9","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1097\/00005344-198608005-00008","volume":"8","author":"M Esler","year":"1986","unstructured":"Esler M, Jennings G, Biviano B, et al.: Mechanism of elevated plasma noradrenaline in the course of essential hypertension. J Cardiovasc Pharmacol 1986, 8(Suppl 5):S39\u2013S43.","journal-title":"J Cardiovasc Pharmacol"},{"issue":"2","key":"78_CR10","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1161\/01.HYP.0000103160.35395.9E","volume":"43","author":"MP Schlaich","year":"2004","unstructured":"Schlaich MP, Lambert E, Kaye DM, et al.: Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation. Hypertension 2004, 43(2):169\u2013175.","journal-title":"Hypertension"},{"issue":"3 Pt 2","key":"78_CR11","doi-asserted-by":"crossref","first-page":"140S","DOI":"10.1093\/ajh\/2.3.140S","volume":"2","author":"M Esler","year":"1989","unstructured":"Esler M, Jennings G, Lambert G: Noradrenaline release and the pathophysiology of primary human hypertension. Am J Hypertens 1989, 2(3 Pt 2):140\u00a0S\u2013146\u00a0S.","journal-title":"Am J Hypertens"},{"issue":"4","key":"78_CR12","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1161\/01.CIR.73.4.615","volume":"73","author":"GJ Hasking","year":"1986","unstructured":"Hasking GJ, Esler MD, Jennings GL, et al.: Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity. Circulation 1986, 73(4):615\u2013621.","journal-title":"Circulation"},{"issue":"3","key":"78_CR13","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1161\/01.HYP.0000055779.93635.A2","volume":"41","author":"A Aggarwal","year":"2003","unstructured":"Aggarwal A, Esler MD, Morris MJ, et al.: Regional sympathetic effects of low-dose clonidine in heart failure. Hypertension 2003, 41(3):553\u2013557.","journal-title":"Hypertension"},{"issue":"9","key":"78_CR14","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/eurheartj\/ehi184","volume":"26","author":"M Petersson","year":"2005","unstructured":"Petersson M, Friberg P, Eisenhofer G, et al.: Long-term outcome in relation to renal sympathetic activity in patients with chronic heart failure. Eur Heart J 2005, 26(9):906\u2013913.","journal-title":"Eur Heart J"},{"issue":"5","key":"78_CR15","first-page":"1192","volume":"37","author":"L Barajas","year":"1978","unstructured":"Barajas L: Innervation of the renal cortex. Fed Proc 1978, 37(5):1192\u20131201.","journal-title":"Fed Proc"},{"issue":"4","key":"78_CR16","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1172\/JCI108355","volume":"57","author":"E Bell-Reuss","year":"1976","unstructured":"Bell-Reuss E, Trevino DL, Gottschalk CW: Effect of renal sympathetic nerve stimulation on proximal water and sodium reabsorption. J Clin Invest 1976, 57(4):1104\u20131107.","journal-title":"J Clin Invest"},{"issue":"17","key":"78_CR17","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1007\/BF01717340","volume":"67","author":"H Kirchheim","year":"1989","unstructured":"Kirchheim H, Ehmke H, Persson P: Sympathetic modulation of renal hemodynamics, renin release and sodium excretion. Klin Wochenschr 1989, 67(17):858\u2013864.","journal-title":"Klin Wochenschr"},{"issue":"1\u20132","key":"78_CR18","first-page":"33","volume":"15","author":"V Kon","year":"1989","unstructured":"Kon V: Neural control of renal circulation. Miner Electrolyte Metab 1989, 15(1\u20132):33\u201343.","journal-title":"Miner Electrolyte Metab"},{"issue":"5","key":"78_CR19","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1161\/01.CIR.56.5.691","volume":"56","author":"AS Zanchetti","year":"1977","unstructured":"Zanchetti AS: Neural regulation of renin release: experimental evidence and clinical implications in arterial hypertension. Circulation 1977, 56(5):691\u2013698.","journal-title":"Circulation"},{"issue":"4","key":"78_CR20","first-page":"184","volume":"10","author":"VM Campese","year":"1997","unstructured":"Campese VM: Neurogenic factors and hypertension in chronic renal failure. J Nephrol 1997, 10(4):184\u2013187.","journal-title":"J Nephrol"},{"issue":"6 Pt 1","key":"78_CR21","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0895-7061(98)00030-2","volume":"11","author":"S Ye","year":"1998","unstructured":"Ye S, Gamburd M, Mozayeni P, et al.: A limited renal injury may cause a permanent form of neurogenic hypertension. Am J Hypertens 1998, 11(6 Pt 1):723\u2013728.","journal-title":"Am J Hypertens"},{"issue":"8","key":"78_CR22","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0895-7061(02)02959-X","volume":"15","author":"S Ye","year":"2002","unstructured":"Ye S, Zhong H, Yanamadala V, Campese VM: Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity. Am J Hypertens 2002, 15(8):717\u2013724.","journal-title":"Am J Hypertens"},{"issue":"Suppl 75","key":"78_CR23","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1046\/j.1523-1755.2000.07511.x","volume":"57","author":"VM Campese","year":"2000","unstructured":"Campese VM: Neurogenic factors and hypertension in renal disease. Kidney Int 2000, 57(Suppl 75):S2\u2013S6.","journal-title":"Kidney Int"},{"issue":"4 Pt 2","key":"78_CR24","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1161\/01.HYP.25.4.878","volume":"25","author":"VM Campese","year":"1995","unstructured":"Campese VM, Kogosov E: Renal afferent denervation prevents hypertension in rats with chronic renal failure. Hypertension 1995, 25(4 Pt 2):878\u2013882.","journal-title":"Hypertension"},{"issue":"5","key":"78_CR25","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/0272-6386(95)90456-5","volume":"26","author":"VM Campese","year":"1995","unstructured":"Campese VM, Kogosov E, Koss M: Renal afferent denervation prevents the progression of renal disease in the renal ablation model of chronic renal failure in the rat. Am J Kidney Dis 1995, 26(5):861\u2013865.","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"78_CR26","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/00041552-200203000-00011","volume":"11","author":"GF DiBona","year":"2002","unstructured":"DiBona GF: Sympathetic nervous system and the kidney in hypertension. Curr Opin Nephrol Hypertens 2002, 11(2):197\u2013200.","journal-title":"Curr Opin Nephrol Hypertens"},{"issue":"3 Pt 2","key":"78_CR27","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1161\/01.HYP.0000047205.52509.8A","volume":"41","author":"GF DiBona","year":"2003","unstructured":"DiBona GF: Neural control of the kidney: past, present, and future. Hypertension 2003, 41(3 Pt 2):621\u2013624.","journal-title":"Hypertension"},{"issue":"4","key":"78_CR28","first-page":"252","volume":"4","author":"J Fajardo","year":"1986","unstructured":"Fajardo J, Lopez-Novoa JM: Effect of chemical sympathectomy on renal hydroelectrolytic handling in dogs with chronic caval constriction. Clin Physiol Biochem 1986, 4(4):252\u2013256.","journal-title":"Clin Physiol Biochem"},{"issue":"5","key":"78_CR29","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/01.HYP.6.5.622","volume":"6","author":"RA Norman Jr","year":"1984","unstructured":"Norman RA Jr, Murphy WR, Dzielak DJ, et al.: Role of the renal nerves in one-kidney, one clip hypertension in rats. Hypertension 1984, 6(5):622\u2013626.","journal-title":"Hypertension"},{"issue":"4","key":"78_CR30","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1161\/01.HYP.0000121881.77212.b1","volume":"43","author":"JA Joles","year":"2004","unstructured":"Joles JA, Koomans HA: Causes and consequences of increased sympathetic activity in renal disease. Hypertension 2004, 43(4):699\u2013706.","journal-title":"Hypertension"},{"issue":"5","key":"78_CR31","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0272-6386(98)70146-5","volume":"32","author":"LU Mailloux","year":"1998","unstructured":"Mailloux LU, Haley WE: Hypertension in the ESRD patient: pathophysiology, therapy, outcomes, and future directions. Am J Kidney Dis 1998, 32(5):705\u2013719.","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"78_CR32","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0272-6386(99)70035-1","volume":"34","author":"E Ritz","year":"1999","unstructured":"Ritz E, Rychlik I, Locatelli F, Halimi S: End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions. Am J Kidney Dis 1999, 34(5):795\u2013808.","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"78_CR33","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1056\/NEJM199601043340103","volume":"334","author":"MJ Klag","year":"1996","unstructured":"Klag MJ, Whelton PK, Randall BL, et al.: Blood pressure and end-stage renal disease in men. N Engl J Med 1996, 334(1):13\u201318.","journal-title":"N Engl J Med"},{"issue":"6","key":"78_CR34","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1681\/ASN.V261053","volume":"2","author":"SG Rostand","year":"1991","unstructured":"Rostand SG, Brunzell JD, Cannon RO 3rd, Victor RG: Cardiovascular complications in renal failure. J Am Soc Nephrol 1991, 2(6):1053\u20131062.","journal-title":"J Am Soc Nephrol"},{"issue":"12","key":"78_CR35","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1056\/NEJM199809173391203","volume":"339","author":"CA Herzog","year":"1998","unstructured":"Herzog CA, Ma JZ, Collins AJ: Poor long-term survival after acute myocardial infarction among patients on long-term dialysis. N Engl J Med 1998, 339(12):799\u2013805.","journal-title":"N Engl J Med"},{"issue":"9","key":"78_CR36","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1001\/archinte.161.9.1207","volume":"161","author":"J Coresh","year":"2001","unstructured":"Coresh J, Wei GL, McQuillan G, et al.: Prevalence of high blood pressure and elevated serum creatinine level in the United States: findings from the third National Health and Nutrition Examination Survey (1988\u20131994). Arch Intern Med 2001, 161(9):1207\u20131216.","journal-title":"Arch Intern Med"},{"issue":"3","key":"78_CR37","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1053\/ajkd.2001.22070","volume":"37","author":"M Tonelli","year":"2001","unstructured":"Tonelli M, Bohm C, Pandeya S, et al.: Cardiac risk factors and the use of cardioprotective medications in patients with chronic renal insufficiency. Am J Kidney Dis 2001, 37(3):484\u2013489.","journal-title":"Am J Kidney Dis"},{"issue":"6","key":"78_CR38","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1001\/archinte.1974.00320180177015","volume":"133","author":"JM Lazarus","year":"1974","unstructured":"Lazarus JM, Hampers C, Merrill JP: Hypertension in chronic renal failure. Treatment with hemodialysis and nephrectomy. Arch Intern Med 1974, 133(6):1059\u20131066.","journal-title":"Arch Intern Med"},{"issue":"17","key":"78_CR39","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1056\/NEJM199904293401704","volume":"340","author":"G Ligtenberg","year":"1999","unstructured":"Ligtenberg G, Blankestijn PJ, Oey PL, et al.: Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure. N Engl J Med 1999, 340(17):1321\u20131328.","journal-title":"N Engl J Med"},{"issue":"20","key":"78_CR40","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1161\/01.CIR.97.20.2037","volume":"97","author":"G Grassi","year":"1998","unstructured":"Grassi G, Seravalle G, Colombo M, et al.: Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans. Circulation 1998, 97(20):2037\u20132042.","journal-title":"Circulation"},{"issue":"6","key":"78_CR41","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1161\/01.HYP.32.6.1039","volume":"32","author":"K Narkiewicz","year":"1998","unstructured":"Narkiewicz K, Pesek CA, Kato M, et al.: Baroreflex control of sympathetic nerve activity and heart rate in obstructive sleep apnea. Hypertension 1998, 32(6):1039\u20131043.","journal-title":"Hypertension"},{"issue":"20","key":"78_CR42","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1056\/NEJM199611143352002","volume":"335","author":"HP Schobel","year":"1996","unstructured":"Schobel HP, Fischer T, Heuszer K, et al.: Preeclampsia\u2014a state of sympathetic overactivity. N Engl J Med 1996, 335(20):1480\u20131485.","journal-title":"N Engl J Med"},{"issue":"11","key":"78_CR43","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1161\/hc1102.105261","volume":"105","author":"C Zoccali","year":"2002","unstructured":"Zoccali C, Mallamaci F, Parlongo S, et al.: Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease. Circulation 2002, 105(11):1354\u20131359.","journal-title":"Circulation"},{"issue":"9","key":"78_CR44","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1097\/00004872-200309000-00021","volume":"21","author":"O Vonend","year":"2003","unstructured":"Vonend O, Marsalek P, Russ H, et al.: Moxonidine treatment of hypertensive patients with advanced renal failure. J Hypertens 2003, 21(9):1709\u20131717.","journal-title":"J Hypertens"},{"issue":"3","key":"78_CR45","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1681\/ASN.V123602","volume":"12","author":"K Strojek","year":"2001","unstructured":"Strojek K, Grzeszczak W, Gorska J, et al.: Lowering of microalbuminuria in diabetic patients by a sympathicoplegic agent: novel approach to prevent progression of diabetic nephropathy? J Am Soc Nephrol 2001, 12(3):602\u2013605.","journal-title":"J Am Soc Nephrol"},{"issue":"6 Suppl 1","key":"78_CR46","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1161\/01.RES.36.6.145","volume":"36","author":"G Onesti","year":"1975","unstructured":"Onesti G, Kim KE, Greco JA, et al.: Blood pressure regulation in end-stage renal disease and anephric man. Circ Res 1975, 36(6 Suppl 1):145\u2013152.","journal-title":"Circ Res"},{"issue":"4","key":"78_CR47","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/ndt\/gfi321","volume":"21","author":"RT Getts","year":"2006","unstructured":"Getts RT, Hazlett SM, Sharma SB, et al.: Regression of left ventricular hypertrophy after bilateral nephrectomy. Nephrol Dial Transplant 2006, 21(4):1089\u20131091.","journal-title":"Nephrol Dial Transplant"},{"issue":"5","key":"78_CR48","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1161\/01.CIR.0000081775.72651.B6","volume":"108","author":"MP Schlaich","year":"2003","unstructured":"Schlaich MP, Kaye DM, Lambert E, et al.: Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy. Circulation 2003, 108(5):560\u2013565.","journal-title":"Circulation"},{"issue":"9671","key":"78_CR49","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S0140-6736(09)60566-3","volume":"373","author":"H Krum","year":"2009","unstructured":"\u2022\u2022 Krum H, Schlaich M, Whitbourn R, et al.: Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet 2009, 373(9671):1275\u20131281. This study presents the first data on the safety and efficacy of a novel catheter-based approach to functionally denervate the human kidney, demonstrating a favorable safety profile and substantial and sustained reductions in blood pressure.","journal-title":"Lancet"},{"issue":"9","key":"78_CR50","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1056\/NEJMc0904179","volume":"361","author":"MP Schlaich","year":"2009","unstructured":"\u2022\u2022 Schlaich MP, Sobotka PA, Krum H, et al.: Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med 2009, 361(9):932\u2013934. This study reports on a patient treated with catheter-based renal nerve ablation, demonstrating a reduction in central sympathetic outflow indicative of a potential involvement of afferent nerve fibers in the sustained blood pressure reduction associated with the procedure.","journal-title":"N Engl J Med"}],"container-title":["Current Hypertension Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11906-009-0078-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11906-009-0078-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11906-009-0078-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T10:37:33Z","timestamp":1634726253000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11906-009-0078-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,16]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["78"],"URL":"https:\/\/doi.org\/10.1007\/s11906-009-0078-6","relation":{},"ISSN":["1522-6417","1534-3111"],"issn-type":[{"value":"1522-6417","type":"print"},{"value":"1534-3111","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,16]]}}}