{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:57:39Z","timestamp":1791939459360,"version":"4.3.4"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Hypertens Rep"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose of Review<\/jats:title>\n                    <jats:p>Hypertension is the primary risk factor for cardiovascular disease and adequate blood pressure control is often elusive. The objective of this work was to conduct a meta-analysis of trial data of isometric resistance training (IRT) studies in people with hypertension, to establish if IRT produced an anti-hypertensive effect. A database search (PubMed, CINAHL, Cochrane Central Register of Controlled Trials, and MEDLINE) identified randomised controlled and crossover trials of IRT versus a sedentary or sham control group in adults with hypertension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Findings<\/jats:title>\n                    <jats:p>\n                      We included 12 studies (14 intervention groups) in the meta-analyses, with an aggregate of 415 participants. IRT reduced systolic blood pressure (SBP), mean difference (MD)\u2009\u2212\u20097.47\u00a0mmHg (95%CI\u2009\u2212\u200910.10,\u2009\u2212\u20094.84),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01; diastolic blood pressure (DBP) MD\u2009\u2212\u20093.17\u00a0mmHg (95%CI\u2009\u2212\u20095.29,\u2009\u2212\u20091.04),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01; and mean arterial blood pressure (MAP) MD\u2009\u2212\u20097.19\u00a0mmHg (95%CI\u2009\u2212\u20099.06,\u2009\u2212\u20095.32),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.0001. Office pulse pressure and resting heart rate was not significantly reduced, neither were 24-h or day-time ambulatory blood pressures (SBP, DBP). Night-time blood pressures, however, were significantly reduced with SBP MD\u2009\u2212\u20094.28\u00a0mmHg (95%CI\u2009\u2212\u20097.88,\u2009\u2212\u20090.67),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.02, and DBP MD\u2009\u2212\u20092.22\u00a0mmHg (95%CI\u2009\u2212\u20093.55,\u2009\u2212\u20090.88),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>IRT does lower SBP, DBP and MAP office and night-time ambulatory SBP and DBP, but not 24-h mean ambulatory blood pressures in people with hypertension.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11906-023-01232-w","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T06:42:28Z","timestamp":1677739348000},"page":"35-49","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Isometric Resistance Training to Manage Hypertension: Systematic Review and Meta-analysis"],"prefix":"10.1007","volume":"25","author":[{"given":"B.","family":"Baffour-Awuah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2639-2615","authenticated-orcid":false,"given":"M. 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