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Although the potential of gene therapy in hypertension is only beginning to become clear, this paper shows that antisense techniques can facilitate the discovery of neural mechanisms underlying hypertension and potentially offer a useful therapy.","journal-title":"Hypertension"},{"key":"29_CR62","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1161\/01.HYP.29.1.374","volume":"29","author":"MI Phillips","year":"1997","unstructured":"Phillips MI, Mohuczy-Dominiak D, Coffey M, et al.: Prolonged reduction of high blood pressure with an in vivo, nonpathogenic, adeno-associated viral vector delivery of AT1-R mRNA antisense. Hypertension 1997, 29:374\u2013380. This paper demonstrates the long-term effects of antisense therapy in the rat.","journal-title":"Hypertension"},{"key":"29_CR63","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1073\/pnas.95.5.2664","volume":"95","author":"JR Martens","year":"1998","unstructured":"Martens JR, Reaves PY, Lu D, et al.: Prevention of renovascular and cardiac pathophysiological changes in hypertension by angiotensin II type 1 receptor antisense gene therapy. Proc Natl Acad Sci USA 1998, 95:2664\u20132669. This paper shows that systemic retroviral therapy can mimic the effects of antisense delivery into the brain.","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Current Hypertension Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11906-999-0029-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11906-999-0029-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11906-999-0029-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T00:14:45Z","timestamp":1559434485000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11906-999-0029-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,5]]},"references-count":63,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,5]]}},"alternative-id":["29"],"URL":"https:\/\/doi.org\/10.1007\/s11906-999-0029-2","relation":{},"ISSN":["1522-6417","1534-3111"],"issn-type":[{"value":"1522-6417","type":"print"},{"value":"1534-3111","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,5]]}}}