{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:50:11Z","timestamp":1791399011546,"version":"4.3.3"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Neurol Neurosci Rep"],"published-print":{"date-parts":[[2001,5]]},"DOI":"10.1007\/s11910-001-0022-x","type":"journal-article","created":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T07:02:52Z","timestamp":1180681372000},"page":"225-232","source":"Crossref","is-referenced-by-count":59,"title":["Migration and invasion in brain neoplasms"],"prefix":"10.1007","volume":"1","author":[{"given":"Anna J.","family":"Bolteus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Berens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey J.","family":"Pilkington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"22_CR1","first-page":"1","volume-title":"Brain Tumors: A Comprehensive Text","author":"K Radhakrishnan","year":"1994","unstructured":"Radhakrishnan K, Bohnen NI, Kurland LT: Epidemiology of brain tumors. In Brain Tumors: A Comprehensive Text. Edited by Morantz RA, Walsh JW. New York: Marcel Dekker; 1994:1\u201318."},{"key":"22_CR2","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/jnci\/91.16.1382","volume":"91","author":"JM Legler","year":"1999","unstructured":"Legler JM, Gloeckler Reis LA, Smith MA, et al.: Brain and other central nervous system cancers: Recent trends in incidence and mortality. J Natl Cancer Inst 1999, 91:1382\u20131390.","journal-title":"J Natl Cancer Inst"},{"key":"22_CR3","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1365-2990.1992.tb00809.x","volume":"18","author":"GJ Pilkington","year":"1992","unstructured":"Pilkington GJ: Glioma heterogeneity in vitro: the significance of growth factors and gangliosides. Neuropathol Appl Neurobiol 1992, 18:434\u2013442.","journal-title":"Neuropathol Appl Neurobiol"},{"key":"22_CR4","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1750-3639.1994.tb00826.x","volume":"4","author":"GJ Pilkington","year":"1994","unstructured":"Pilkington GJ: Tumour cell migration in the central nervous system. Brain Pathol 1994, 4:157\u2013166.","journal-title":"Brain Pathol"},{"key":"22_CR5","first-page":"1159","volume":"29","author":"GJ Pilkington","year":"1996","unstructured":"Pilkington GJ: The role of the extracellular matrix in neoplastic glial invasion of the nervous system. Brazilian J Med Biol Rese 1996, 29:1159\u20131172.","journal-title":"Brazilian J Med Biol Rese"},{"key":"22_CR6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0304-3835(97)00171-7","volume":"116","author":"SL Maidment","year":"1997","unstructured":"Maidment SL, Rucklidge GJ, Rooprai HK, et al.: An inverse correlation between expression of NCAM-A and the matrixmetalloproteinases gelatinase-A and gelatinase-B in human glioma cells in vitro. Cancer Lett 1997, 116:71\u201377.","journal-title":"Cancer Lett"},{"key":"22_CR7","first-page":"4111","volume":"17","author":"A Gratsa","year":"1997","unstructured":"Gratsa A, Rooprai HK, Rogers JP, et al.: Correlation of expression of NCAM and GD3 ganglioside to motile behaviour in neoplastic glia. Anticancer Res 1997, 17:4111\u20134117.","journal-title":"Anticancer Res"},{"key":"22_CR8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/bjc.1994.280","volume":"70","author":"A Merzak","year":"1994","unstructured":"Merzak A, McCrea S, Koochekpour S, et al.: Control of human glioma cell growth, migration and invasion in vitro by transforming growth factor B1. Br J Cancer 1994, 70:199\u2013203.","journal-title":"Br J Cancer"},{"key":"22_CR9","first-page":"4947","volume":"19","author":"A Sehgal","year":"1999","unstructured":"Sehgal A, Ricks S, Warrick J, et al.: Antisense human neuroglia related cell adhesion molecule hNr-CAM, reduces the tumorigenic properties of human glioblastoma cells. Anticancer Res 1999, 19:4947\u20134953.","journal-title":"Anticancer Res"},{"key":"22_CR10","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3171\/jns.1994.80.3.0515","volume":"80","author":"W Paulus","year":"1994","unstructured":"Paulus W, Tonn JC: Basement-membrane invasion of glioma cells mediated by integrin receptors. J Neurosurg 1994, 80:515\u2013519.","journal-title":"J Neurosurg"},{"key":"22_CR11","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0736-5748(99)00051-9","volume":"17","author":"HK Rooprai","year":"1999","unstructured":"Rooprai HK, Vanmeter T, Panou C, et al.: The role of integrin receptors in aspects of glioma invasion in vitro. Int J Dev Neurosci 1999, 17:613\u2013623.","journal-title":"Int J Dev Neurosci"},{"key":"22_CR12","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3109\/15419069509081276","volume":"3","author":"A Merzak","year":"1995","unstructured":"Merzak A, Koochekpour S, Pilkington GJ: Adhesion of human glioma cell lines to fibronectin, laminin, vitronectin and collagen I is modulated by gangliosides in vitro. Cell Adhes Commun 1995, 3:27\u201343.","journal-title":"Cell Adhes Commun"},{"key":"22_CR13","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF02962138","volume":"24","author":"A Merzak","year":"1995","unstructured":"Merzak A, Koochekpour S, McCrea S, et al.: Gangliosides modulate proliferation, migration, and invasiveness of human brain tumor cells in vitro. Mol Chem Neuropathol 1995, 24:121\u2013135.","journal-title":"Mol Chem Neuropathol"},{"key":"22_CR14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0304-3940(95)11280-A","volume":"186","author":"S Koochekpour","year":"1995","unstructured":"Koochekpour S, Merzak A, Pilkington GJ: Growth factors and gangliosides stimulate laminin production by human glioma cells in vitro. Neurosci Lett 1995, 186:53\u201356.","journal-title":"Neurosci Lett"},{"key":"22_CR15","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/0959-8049(95)00659-1","volume":"32","author":"SL Maidment","year":"1996","unstructured":"Maidment SL, Merzak A, Koochekpour S, et al.: The effect of exogenous gangliosides on matrix metalloproteinase secretion by human glioma cells in vitro. Eur J Cancer 1996, 32:868\u2013871.","journal-title":"Eur J Cancer"},{"key":"22_CR16","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0304-3835(96)04161-4","volume":"102","author":"S Koochekpour","year":"1996","unstructured":"Koochekpour S, Merzak A, Pilkington GJ: Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro. Cancer Lett 1996, 102:209\u2013215.","journal-title":"Cancer Lett"},{"key":"22_CR17","first-page":"1079","volume":"6","author":"A Merzak","year":"1995","unstructured":"Merzak A, Koochekpour S, Dkhissi F, et al.: Synergism between growth factors in the control of glioma cell proliferation, migration and invasion in vitro. Int J Oncol 1995, 6:1079\u20131085.","journal-title":"Int J Oncol"},{"key":"22_CR18","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0736-5748(99)00049-0","volume":"17","author":"JT Rutka","year":"1999","unstructured":"Rutka JT, Ivanchuk S, Mondal S, et al.: Co-expression of nestin and vimentin intermediate filaments in invasive human astrocytoma cells. Int J Dev Neurosci 1999, 17:503\u2013515. Important study.","journal-title":"Int J Dev Neurosci"},{"key":"22_CR19","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/ng0497-356","volume":"15","author":"PA Steck","year":"1997","unstructured":"Steck PA, Pershouse MA, Jasser SA, et al.: Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nature Genet 1997, 15:356\u2013362.","journal-title":"Nature Genet"},{"key":"22_CR20","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1126\/science.275.5308.1943","volume":"275","author":"J Li","year":"1997","unstructured":"Li J, Yen C, Liaw D, et al.: PTEN, a putative protein tyrosine phospatase gene mutated in human brain, breast, and prostatic cancer. Science 1997, 275:1943\u20131947.","journal-title":"Science"},{"key":"22_CR21","first-page":"5479","volume":"59","author":"D Maier","year":"1999","unstructured":"Maier D, Jones G, Li X, Schonthal AH, et al.: The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells. Cancer Res 1999, 59:5479\u20135482.","journal-title":"Cancer Res"},{"key":"22_CR22","first-page":"3988","volume":"54","author":"A Merzak","year":"1994","unstructured":"Merzak A, Koochekpour S, Pilkington GJ: CD44 mediates human glioma cell adhesion and invasion in vitro. Cancer Res 1994, 54:3988\u20133992.","journal-title":"Cancer Res"},{"key":"22_CR23","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/(SICI)1097-0215(19960410)66:2<255::AID-IJC20>3.0.CO;2-A","volume":"66","author":"H Okada","year":"1996","unstructured":"Okada H, Yoshida J, Sokabe M, et al.: Suppression of CD44 expression decreased migration and invasion of human glioma cells. Int J Cancer 1996, 66:255\u2013260.","journal-title":"Int J Cancer"},{"key":"22_CR24","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3171\/jns.2000.92.1.0140","volume":"92","author":"R Breyer","year":"2000","unstructured":"Breyer R, Hussein S, Radu DL, et al.: Disruption of intracerebral progression of C6 rat glioblastoma by in vivo treatment with anti-CD44 monoclonal antibody. J Neurosurg 2000, 92:140\u2013149. Authors conclude that CD44-targeted treatment with specific mAb may represent an effective means for preventing progression of invasive gliblastoma mulitformes.","journal-title":"J Neurosurg"},{"key":"22_CR25","doi-asserted-by":"crossref","first-page":"25525","DOI":"10.1074\/jbc.274.36.25525","volume":"274","author":"I Okamoto","year":"1999","unstructured":"Okamoto I, Kawano Y, Matsumoto M, et al.: Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins. J Biol Chem 1999, 274:25525\u201325534.","journal-title":"J Biol Chem"},{"key":"22_CR26","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1006\/geno.1996.0385","volume":"35","author":"RP Lane","year":"1996","unstructured":"Lane RP, Chen XN, Yamakawa K, et al.: Characterization of a highly conserved human homolog to the chicken neural cell surface protein bravo\/NrCAM that maps to chromosome band 7q31. Genomics 1996, 35:456\u2013465.","journal-title":"Genomics"},{"key":"22_CR27","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/(SICI)1097-0215(19980518)76:4<451::AID-IJC1>3.0.CO;2-Q","volume":"76","author":"A Sehgal","year":"1998","unstructured":"Sehgal A, Boynton AL, Young RF, et al.: Cell adhesion molecule Nr-CAM is over-expressed in human brain tumors. Int J Cancer 1998, 76:451\u2013458.","journal-title":"Int J Cancer"},{"key":"22_CR28","first-page":"4947","volume":"19","author":"A Sehgal","year":"1999","unstructured":"Sehgal A, Ricks S, Warrick J, et al.: Antisense human neuroglia related cell adhesion molecule hHr-CAM, reduces the tumorigenic properties of human glioblastoma cells. Anticancer Res 1999, 19:4947\u20134953.","journal-title":"Anticancer Res"},{"key":"22_CR29","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1023\/A:1006331416283","volume":"44","author":"H Bouterfa","year":"1999","unstructured":"Bouterfa H, Darlapp AR, Klein E, et al.: Expression of different extracellular matrix components in human brain tumor and melanoma cells in respect to variant culture conditions. J Neurooncol 1999, 44:23\u201333.","journal-title":"J Neurooncol"},{"key":"22_CR30","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/(SICI)1098-1136(19990115)25:2<179::AID-GLIA8>3.0.CO;2-B","volume":"25","author":"S Jung","year":"1999","unstructured":"Jung S, Hinek A, Tsugu A, et al.: Astrocytoma cell interaction with elastin substrates: implications for astrocytoma invasive potential. Glia 1999, 25:179\u2013189.","journal-title":"Glia"},{"key":"22_CR31","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1046\/j.1365-2990.1999.00181.x","volume":"25","author":"C Hagel","year":"1999","unstructured":"Hagel C, Stavrou DK: CD44 expression in primary and recurrent oligodendrogliomas and in adjacent gliotic brain tissue. Neuropathol Appl Neurobiol 1999, 25:313\u2013318.","journal-title":"Neuropathol Appl Neurobiol"},{"key":"22_CR32","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1038\/sj.bjc.6990291","volume":"79","author":"PA Forsyth","year":"1999","unstructured":"Forsyth PA, Wong H, Laing TD, et al.: Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. Br J Cancer 1999, 79:1828\u20131835. Data suggest that gelatinase-A and -B and MT1-MMP are important in the pathophysiology of human gliomas.","journal-title":"Br J Cancer"},{"key":"22_CR33","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0002-9440(10)65288-1","volume":"154","author":"M Nakada","year":"1999","unstructured":"Nakada M, Nakamura H, Ikeda E, et al.: Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors. Am J Pathol 1999, 154:417\u2013428.","journal-title":"Am J Pathol"},{"key":"22_CR34","doi-asserted-by":"crossref","first-page":"29130","DOI":"10.1074\/jbc.274.41.29130","volume":"274","author":"H Qin","year":"1999","unstructured":"Qin H, Sun Y, Benveniste EN: The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells. J Biol Chem 1999, 274:29130\u201329137.","journal-title":"J Biol Chem"},{"key":"22_CR35","first-page":"877","volume":"60","author":"G Velasco","year":"2000","unstructured":"Velasco G, Cal S, Merlos-Suarez A, et al.: Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors. Cancer Res 2000, 60:877\u2013882.","journal-title":"Cancer Res"},{"key":"22_CR36","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1054\/bjoc.1999.0876","volume":"82","author":"HK Rooprai","year":"2000","unstructured":"Rooprai HK, Rucklidge GJ, Panou C, et al.: The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells. Br J Cancer 2000, 82:52\u201355.","journal-title":"Br J Cancer"},{"key":"22_CR37","first-page":"618","volume":"12","author":"G Kitange","year":"1999","unstructured":"Kitange G, Kishikawa M, Nakayama T, et al.: Expression of the Ets-1 proto-oncogene correlates with malignant potential in human astrocytic tumors. Mod Pathol 1999, 12:618\u2013626.","journal-title":"Mod Pathol"},{"key":"22_CR38","first-page":"407","volume":"79","author":"G Kitange","year":"1999","unstructured":"Kitange G, Shibata S, Tokunaga Y, et al.: Ets-1 transcription factor-mediated urokinase-type plasminogen activator expression and invasion in glioma cells stimulated by serum and basic fibroblast growth factors. Lab Invest 1999, 79:407\u2013416.","journal-title":"Lab Invest"},{"key":"22_CR39","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1002\/(SICI)1097-0215(19990301)80:5<764::AID-IJC22>3.0.CO;2-J","volume":"80","author":"JC Tonn","year":"1999","unstructured":"Tonn JC, Kerkau S, Hanke A, et al.: Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro. Int J Cancer 1999, 80:764\u2013772.","journal-title":"Int J Cancer"},{"key":"22_CR40","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1038\/sj.onc.1201382","volume":"15","author":"SK Chintala","year":"1997","unstructured":"Chintala SK, Fueyo J, Gomez-Manzano C, et al.: Adenovirusmediated p16\/CDKN2 gene transfer suppresses glioma invasion in vitro. Oncogene 1997, 15:2049\u20132057.","journal-title":"Oncogene"},{"key":"22_CR41","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0736-5748(99)00011-8","volume":"17","author":"LL Demchik","year":"1999","unstructured":"Demchik LL, Sameni M, Nelson K, et al.: Cathepsin B and glioma invasion. Int J Dev Neurosci 1999, 17:483\u2013494.","journal-title":"Int J Dev Neurosci"},{"key":"22_CR42","doi-asserted-by":"crossref","first-page":"12806","DOI":"10.1074\/jbc.275.17.12806","volume":"275","author":"J Mai","year":"2000","unstructured":"Mai J, Finley RL Jr, Waisman DM, et al.: Human procathepsin B interacts with the annexin II tetramer on the surface of tumor cells. J Biol Chem 2000, 275:12806\u201312812.","journal-title":"J Biol Chem"},{"key":"22_CR43","first-page":"3369","volume":"59","author":"PM Mohan","year":"1999","unstructured":"Mohan PM, Chintala SK, Mohanam S, et al.: Adenovirusmediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth. Cancer Res 1999, 59:3369\u20133373.","journal-title":"Cancer Res"},{"key":"22_CR44","first-page":"6246","volume":"59","author":"U Novak","year":"1999","unstructured":"Novak U, Stylli SS, Kaye AH, et al.: Hyaluronidase-2 overexpression accelerates intracerebral but not subcutaneous tumor formation of murine astrocytoma cells. Cancer Res 1999, 59:6246\u20136250.","journal-title":"Cancer Res"},{"key":"22_CR45","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0736-5748(99)00008-8","volume":"17","author":"K Lamszus","year":"1999","unstructured":"Lamszus K, Laterra J, Westphal M, et al.: Scatter factor\/hepatocyte growth factor (SF\/HGF) content and function in human gliomas. Int J Dev Neurosci 1999, 17:517\u2013530.","journal-title":"Int J Dev Neurosci"},{"key":"22_CR46","first-page":"1635","volume":"19","author":"WC Welch","year":"1999","unstructured":"Welch WC, Kornblith PL, Michalopoulos GK, et al.: Hepatocyte growth factor (HGF) and receptor (c-met) in normal and malignant astrocytic cells. Anticancer Res 1999, 19:1635\u20131640.","journal-title":"Anticancer Res"},{"key":"22_CR47","first-page":"531","volume":"3","author":"T Moriyama","year":"1999","unstructured":"Moriyama T, Kataoka H, Koono M, et al.: Expression of hepatocyte growth factor\/scatter factor and its receptor c-Met in brain tumors: evidence for a role in progression of astrocytic tumors [review]. Int J Mol Med 1999, 3:531\u2013536.","journal-title":"Int J Mol Med"},{"key":"22_CR48","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/S0002-9440(10)65472-7","volume":"155","author":"MM Mueller","year":"1999","unstructured":"Mueller MM, Herold-Mende CC, Riede D, et al.: Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression. Am J Pathol 1999, 155:1557\u20131567.","journal-title":"Am J Pathol"},{"key":"22_CR49","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/jnen\/59.1.18","volume":"59","author":"K Miyake","year":"2000","unstructured":"Miyake K, Kimura S, Nakanishi M, et al.: Transforming growth factor-beta1 stimulates contraction of human glioblastoma cell-mediated collagen lattice through enhanced alpha2 integrin expression. J Neuropathol Exp Neurol 2000, 59:18\u201328.","journal-title":"J Neuropathol Exp Neurol"},{"key":"22_CR50","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1023\/A:1006375316331","volume":"45","author":"S Khoshyomn","year":"1999","unstructured":"Khoshyomn S, Lew S, DeMattia J, et al.: Brain tumor invasion rate measured in vitro does not correlate with Ki-67 expression. J Neurooncol 1999, 45:111\u2013116.","journal-title":"J Neurooncol"},{"key":"22_CR51","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0736-5748(99)00019-2","volume":"17","author":"M Chekenya","year":"1999","unstructured":"Chekenya M, Rooprai HK, Davies D, et al.: The NG2 chondroitin sulfate proteoglycan: role in malignant progression of human brain tumours. Int J Dev Neurosci 1999, 17:421\u2013435.","journal-title":"Int J Dev Neurosci"}],"container-title":["Current Neurology and Neuroscience Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11910-001-0022-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11910-001-0022-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11910-001-0022-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T20:24:23Z","timestamp":1559420663000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11910-001-0022-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["22"],"URL":"https:\/\/doi.org\/10.1007\/s11910-001-0022-x","relation":{},"ISSN":["1528-4042","1534-6293"],"issn-type":[{"value":"1528-4042","type":"print"},{"value":"1534-6293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}