{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:35:36Z","timestamp":1760783736373},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2013,10,20]],"date-time":"2013-10-20T00:00:00Z","timestamp":1382227200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Neurol Neurosci Rep"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1007\/s11910-013-0405-9","type":"journal-article","created":{"date-parts":[[2013,10,18]],"date-time":"2013-10-18T22:23:34Z","timestamp":1382135014000},"source":"Crossref","is-referenced-by-count":6,"title":["Imaging of Neuroinflammation in Parkinsonian Syndromes with Positron Emission Tomography"],"prefix":"10.1007","volume":"13","author":[{"given":"Alexander","family":"Gerhard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,10,20]]},"reference":[{"key":"405_CR1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1742-2094-1-14","volume":"1","author":"WJ Streit","year":"2004","unstructured":"Streit WJ, Mrak RE, Griffin WS. Microglia and neuroinflammation: a pathological perspective. J Neuroinflammation. 2004;1:14.","journal-title":"J Neuroinflammation"},{"key":"405_CR2","unstructured":"del Rio-Hortega P. In: Penfield W, editors. Cytology and cellular pathology of the nervous system. New York: Hafner; 1932. p. 482\u2013584."},{"key":"405_CR3","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0165-0173(94)00015-H","volume":"20","author":"J Gehrmann","year":"1995","unstructured":"Gehrmann J, Matsumoto Y, Kreutzberg GW. Microglia: intrinsic immuneffector cell of the brain. Brain Res Brain Res Rev. 1995;20:269\u201387.","journal-title":"Brain Res Brain Res Rev"},{"key":"405_CR4","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1126\/science.1110647","volume":"308","author":"A Nimmerjahn","year":"2005","unstructured":"Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science. 2005;308:1314\u20138 [Epub Apr 14 2005].","journal-title":"Science"},{"key":"405_CR5","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/0166-2236(96)10049-7","volume":"19","author":"GW Kreutzberg","year":"1996","unstructured":"Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996;19:312\u20138.","journal-title":"Trends Neurosci"},{"key":"405_CR6","doi-asserted-by":"crossref","unstructured":"\u2022 Kettenmann H, Hanisch UK, Noda M, Verkhratsky A. Physiology of microglia. Physiological Rev. 2011;91:461\u2013553. PubMed PMID: 21527731. [Epub Apr 30 2011]. Excellent in depth review of microglial physiology.","DOI":"10.1152\/physrev.00011.2010"},{"key":"405_CR7","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1076\/jhin.11.4.325.8531","volume":"11","author":"P Rezaie","year":"2002","unstructured":"Rezaie P, Male D. Mesoglia and microglia\u2014a historical review of the concept of mononuclear phagocytes within the central nervous system. J Hist Neurosci. 2002;11:325\u201374.","journal-title":"J Hist Neurosci"},{"key":"405_CR8","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.parkreldis.2004.03.006","volume":"10","author":"DB Calne","year":"2004","unstructured":"Calne DB, Mizuno Y. The neuromythology of Parkinson\u2019s Disease. Parkinsonism Relat Disord. 2004;10:319\u201322.","journal-title":"Parkinsonism Relat Disord"},{"key":"405_CR9","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0197-4580(02)00065-9","volume":"24","author":"H Braak","year":"2003","unstructured":"Braak H, Del Tredici K, Rub U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson\u2019s disease. Neurobiol Aging. 2003;24:197\u2013211.","journal-title":"Neurobiol Aging"},{"key":"405_CR10","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1212\/WNL.38.8.1285","volume":"38","author":"PL McGeer","year":"1988","unstructured":"McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson\u2019s and Alzheimer\u2019s disease brains. Neurology. 1988;38:1285\u201391.","journal-title":"Neurology"},{"key":"405_CR11","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/s00401-003-0766-2","volume":"106","author":"K Imamura","year":"2003","unstructured":"Imamura K, Hishikawa N, Sawada M, Nagatsu T, Yoshida M, Hashizume Y. Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson\u2019s disease brains. Acta Neuropathol. 2003;106:518\u201326 [Epub Sep 25 2003].","journal-title":"Acta Neuropathol"},{"key":"405_CR12","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1002\/1531-8249(199910)46:4<598::AID-ANA7>3.0.CO;2-F","volume":"46","author":"JW Langston","year":"1999","unstructured":"Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure [see comments]. Ann Neurol. 1999;46:598\u2013605.","journal-title":"Ann Neurol"},{"key":"405_CR13","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1002\/ana.10728","volume":"54","author":"PL McGeer","year":"2003","unstructured":"McGeer PL, Schwab C, Parent A, Doudet D. Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. Ann Neurol. 2003;54:599\u2013604.","journal-title":"Ann Neurol"},{"key":"405_CR14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/jnen\/63.1.43","volume":"63","author":"K Ishizawa","year":"2004","unstructured":"Ishizawa K, Komori T, Sasaki S, Arai N, Mizutani T, Hirose T. Microglial activation parallels system degeneration in multiple system atrophy. J Neuropathol Exp Neurol. 2004;63:43\u201352.","journal-title":"J Neuropathol Exp Neurol"},{"key":"405_CR15","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1097\/00005072-199809000-00002","volume":"57","author":"S Probst Cousin","year":"1998","unstructured":"Probst Cousin S, Rickert CH, Schmid KW, Gullotta F. Cell death mechanisms in multiple system atrophy. J Neuropathol Exp Neurol. 1998;57:814\u201321.","journal-title":"J Neuropathol Exp Neurol"},{"key":"405_CR16","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1097\/00001756-199809140-00020","volume":"9","author":"SC Schwarz","year":"1998","unstructured":"Schwarz SC, Seufferlein T, Liptay S, Schmid RM, Kasischke K, Foster OJ, et al. Microglial activation in multiple system atrophy: a potential role for NF-kappaB\/rel proteins. Neuroreport. 1998;9:3029\u201332.","journal-title":"Neuroreport"},{"key":"405_CR17","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1212\/WNL.44.11.2015","volume":"44","author":"JJ Hauw","year":"1994","unstructured":"Hauw JJ, Daniel SE, Dickson D, Horoupian DS, Jellinger K, Lantos PL, et al. Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy). Neurology. 1994;44:2015\u20139.","journal-title":"Neurology"},{"key":"405_CR18","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1093\/jnen\/60.6.647","volume":"60","author":"K Ishizawa","year":"2001","unstructured":"Ishizawa K, Dickson DW. Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration. J Neuropathol Exp Neurol. 2001;60:647\u201357.","journal-title":"J Neuropathol Exp Neurol"},{"key":"405_CR19","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1093\/jnen\/61.11.935","volume":"61","author":"DW Dickson","year":"2002","unstructured":"Dickson DW, Bergeron C, Chin SS, Duyckaerts C, Horoupian D, Ikeda K, et al. Office of Rare Diseases neuropathologic criteria for corticobasal degeneration. J Neuropathol Exp Neurol. 2002;61:935\u201346.","journal-title":"J Neuropathol Exp Neurol"},{"key":"405_CR20","doi-asserted-by":"crossref","unstructured":"\u2022\u2022 Perry VH. Innate inflammation in Parkinson\u2019s disease. Cold Spring Harb Perspect Med. 2012;2:a009373. PubMed PMID: 22951445. [Epub Sep 7 2012]. Critical review of the current problems in undestanding the role of microglia in Parkinson\u2019s disease.","DOI":"10.1101\/cshperspect.a009373"},{"key":"405_CR21","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.tips.2006.06.005","volume":"27","author":"V Papadopoulos","year":"2006","unstructured":"Papadopoulos V, Baraldi M, Guilarte TR, Knudsen TB, Lacapere JJ, Lindemann P, et al. Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends Pharmacol Sci. 2006;27:402\u20139 [Epub Jul 5 2006].","journal-title":"Trends Pharmacol Sci"},{"issue":"6","key":"405_CR22","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.pneurobio.2006.10.002","volume":"80","author":"S Venneti","year":"2006","unstructured":"Venneti S, Lopresti BJ, Wiley CA. The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging. Prog Neurobiol. 2006;80(6):308\u201322 [Epub Dec 6 2006].","journal-title":"Prog Neurobiol"},{"key":"405_CR23","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1111\/j.1471-4159.1983.tb00888.x","volume":"41","author":"J Benavides","year":"1983","unstructured":"Benavides J, Quarteronet D, Imbault F, Malgouris C, Uzan A, Renault C, et al. Labelling of \u201cperipheral-type\u201d benzodiazepine binding sites in the rat brain by using [3H]PK 11195, an isoquinoline carboxamide derivative: kinetic studies and autoradiographic localization. J Neurochem. 1983;41:1744\u201350.","journal-title":"J Neurochem"},{"key":"405_CR24","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1023\/A:1018567510105","volume":"26","author":"RB Banati","year":"1997","unstructured":"Banati RB, Myers R, Kreutzberg GW. PK (\u2018peripheral benzodiazepine\u2019)\u2014binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia. J Neurocytol. 1997;26:77\u201382.","journal-title":"J Neurocytol"},{"key":"405_CR25","first-page":"1","volume":"1","author":"F Chauveau","year":"2008","unstructured":"Chauveau F, Boutin H, Van Camp N, Dolle F, Tavitian B. Nuclear imaging of neuroinflammation: a comprehensive review of [(11)C]PK11195 challengers. Eur J Nucl Med Mol Imaging. 2008;1:1.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"405_CR26","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.nbd.2005.08.002","volume":"21","author":"A Gerhard","year":"2006","unstructured":"Gerhard A, Pavese N, Hotton G, Turkheimer F, Es M, Hammers A, et al. In vivo imaging of microglial activation with [(11)C](R)-PK11195 PET in idiopathic Parkinson\u2019s disease. Neurobiol Dis. 2006;21:404\u201312 [Epub Sep 21 2005].","journal-title":"Neurobiol Dis"},{"key":"405_CR27","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/ana.20338","volume":"57","author":"Y Ouchi","year":"2005","unstructured":"Ouchi Y, Yoshikawa E, Sekine Y, Futatsubashi M, Kanno T, Ogusu T, et al. Microglial activation and dopamine terminal loss in early Parkinson\u2019s disease. Ann Neurol. 2005;57:168\u201375.","journal-title":"Ann Neurol"},{"key":"405_CR28","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.parkreldis.2012.07.002","volume":"19","author":"S Iannaccone","year":"2013","unstructured":"Iannaccone S, Cerami C, Alessio M, Garibotto V, Panzacchi A, Olivieri S, et al. In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson\u2019s disease. Parkinsonism Relat Disord. 2013;19:47\u201352. PubMed PMID: 22841687. [Epub Jul 31 2012].","journal-title":"Parkinsonism Relat Disord"},{"key":"405_CR29","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1038\/npp.2012.255","volume":"38","author":"P Edison","year":"2013","unstructured":"Edison P, Ahmed I, Fan Z, Hinz R, Gelosa G, Ray Chaudhuri K, et al. Microglia, amyloid, and glucose metabolism in Parkinson\u2019s disease with and without dementia. Neuropsychopharmacology. 2013;38:938\u201349. PubMed PMID: 23303049. Pubmed Central PMCID: PMC3629382. [Epub Jan 11 2013].","journal-title":"Neuropsychopharmacology"},{"key":"405_CR30","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1212\/01.WNL.0000078192.95645.E6","volume":"61","author":"A Gerhard","year":"2003","unstructured":"Gerhard A, Banati RB, Goerres GB, Cagnin A, Myers R, Gunn RN, et al. [11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy. Neurology. 2003;61:686\u20139.","journal-title":"Neurology"},{"key":"405_CR31","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/mds.22732","volume":"25","author":"R Dodel","year":"2010","unstructured":"\u2022 Dodel R, Spottke A, Gerhard A, Reuss A, Reinecker S, Schimke N, et al. Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial). Mov Disord. 2010;25:11. First study to demonstrate that PET can be used in vivo in man to monitor the effect of drugs suppressing microglial activation..","journal-title":"Mov Disord"},{"key":"405_CR32","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/mds.20668","volume":"21","author":"A Gerhard","year":"2006","unstructured":"Gerhard A, Trender-Gerhard I, Turkheimer F, Quinn NP, Bhatia KP, Brooks DJ. In vivo imaging of microglial activation with [(11)C](R)-PK11195 PET in progressive supranuclear palsy. Mov Disord. 2006;21:89\u201393.","journal-title":"Mov Disord"},{"key":"405_CR33","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1002\/mds.20162","volume":"19","author":"A Gerhard","year":"2004","unstructured":"Gerhard A, Watts J, Trender-Gerhard I, Turkheimer F, Banati RB, Bhatia K, et al. In vivo imaging of microglial activation with [(11)C](R)-PK11195 PET in corticobasal degeneration. Mov Disord. 2004;19:1221\u20136.","journal-title":"Mov Disord"},{"key":"405_CR34","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.parkreldis.2013.01.017","volume":"19","author":"C Kobylecki","year":"2013","unstructured":"Kobylecki C, Counsell SJ, Cabanel N, Wachter T, Turkheimer FE, Eggert K, et al. Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes. Parkinsonism Relat Disord. 2013;19:527\u201332. PubMed PMID: 23425503. [Epub Feb 22 2013].","journal-title":"Parkinsonism Relat Disord"},{"key":"405_CR35","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/sj.bjp.0707584","volume":"153","author":"GA Cabral","year":"2008","unstructured":"Cabral GA, Raborn ES, Griffin L, Dennis J, Marciano-Cabral F. CB2 receptors in the brain: role in central immune function. Br J Pharmacol. 2008;153:240\u201351. PubMed PMID: 18037916. Pubmed Central PMCID: PMC2219530. [Epub Nov 27 2007].","journal-title":"Br J Pharmacol"},{"issue":"8","key":"405_CR36","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1523\/JNEUROSCI.4540-04.2005","volume":"25","author":"BG Ramirez","year":"2005","unstructured":"Ramirez BG, Blazquez C, Gomez del Pulgar T, Guzman M, de Ceballos ML. Prevention of Alzheimer\u2019s disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation. J Neurosci. 2005;25(8):1904\u201313. PubMed PMID: 15728830. [Epub Feb 25 2005].","journal-title":"J Neurosci"},{"issue":"Pt 11","key":"405_CR37","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1093\/brain\/awp239","volume":"132","author":"J Palazuelos","year":"2009","unstructured":"Palazuelos J, Aguado T, Pazos MR, Julien B, Carrasco C, Resel E, et al. Microglial CB2 cannabinoid receptors are neuroprotective in Huntington\u2019s disease excitotoxicity. Brain. 2009;132(Pt 11):3152\u201364. PubMed PMID: 19805493. [Epub Oct 7 2009].","journal-title":"Brain"},{"key":"405_CR38","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.nucmedbio.2011.09.005","volume":"39","author":"N Evens","year":"2012","unstructured":"Evens N, Vandeputte C, Coolen C, Janssen P, Sciot R, Baekelandt V, et al. Preclinical evaluation of [11C]NE40, a type 2 cannabinoid receptor PET tracer. Nucl Med Biol. 2012;39:389\u201399. PubMed PMID: 22154685. [Epub Dec 14 2011].","journal-title":"Nucl Med Biol"},{"key":"405_CR39","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1007\/s11307-013-0626-y","volume":"15","author":"R Ahmad","year":"2013","unstructured":"Ahmad R, Koole M, Evens N, Serdons K, Verbruggen A, Bormans G, et al. Whole-body biodistribution and radiation dosimetry of the cannabinoid Type 2 Receptor Ligand [(11)C]-NE40 in Healthy Subjects. Mol Imaging Biol. 2013;15:384\u201390. PubMed PMID: 23508466. [Epub Mar 20 2013].","journal-title":"Mol Imaging Biol"},{"key":"405_CR40","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/BF00307697","volume":"80","author":"S Nakamura","year":"1990","unstructured":"Nakamura S, Kawamata T, Akiguchi I, Kameyama M, Nakamura N, Kimura H. Expression of monoamine oxidase B activity in astrocytes of senile plaques. Acta Neuropathol. 1990;80:419\u201325. PubMed PMID: 2239154 [Epub Jan 1 1990].","journal-title":"Acta Neuropathol"},{"key":"405_CR41","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.neuint.2010.10.013","volume":"58","author":"B Gulyas","year":"2011","unstructured":"Gulyas B, Pavlova E, Kasa P, Gulya K, Bakota L, Varszegi S, et al. Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography. Neurochem Int. 2011;58:60\u20138. PubMed PMID: 21075154. [Epub Nov 16 2010].","journal-title":"Neurochem Int"},{"key":"405_CR42","first-page":"1255","volume":"36","author":"JS Fowler","year":"1995","unstructured":"Fowler JS, Wang GJ, Logan J, Xie S, Volkow ND, MacGregor RR, et al. Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11- deprenyl-D2 for MAO B mapping. J Nucl Med. 1995;36:1255.","journal-title":"J Nucl Med"},{"key":"405_CR43","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2967\/jnumed.110.087031","volume":"53","author":"SF Carter","year":"2012","unstructured":"Carter SF, Scholl M, Almkvist O, Wall A, Engler H, Langstrom B, et al. Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG. J Nucl Med. 2012;53:37\u201346. PubMed PMID: 22213821. [Epub Jan 4 2012].","journal-title":"J Nucl Med"},{"issue":"Pt 1","key":"405_CR44","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/brain\/awq349","volume":"134","author":"A Kadir","year":"2011","unstructured":"Kadir A, Marutle A, Gonzalez D, Scholl M, Almkvist O, Mousavi M, et al. Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer\u2019s disease. Brain. 2011;134(Pt 1):301\u201317. PubMed PMID: 21149866. Pubmed Central PMCID: PMC3009843. [Epub Dec 15 2010].","journal-title":"Brain"},{"key":"405_CR45","doi-asserted-by":"crossref","unstructured":"Hazell AS, Desjardins P, Butterworth RF. Chronic exposure of rat primary astrocyte cultures to manganese results in increased binding sites for the \u2018peripheral-type\u2019 benzodiazepine receptor ligand 3H-PK 11195. Neurosci Lett. 1999;271:5\u20138. PubMed PMID: 10471200. [Epub Sep 2 1999].","DOI":"10.1016\/S0304-3940(99)00489-9"},{"key":"405_CR46","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1097\/NEN.0b013e318188b204","volume":"67","author":"S Venneti","year":"2008","unstructured":"Venneti S, Wang GJ, Nguyen J, Wiley CA. The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders. J Neuropathol Exp Neurol. 2008;67:1001\u201310. PubMed PMID: ISI:000259793100009.","journal-title":"J Neuropathol Exp Neurol"},{"key":"405_CR47","first-page":"158","volume":"48","author":"FE Turkheimer","year":"2007","unstructured":"Turkheimer FE, Edison P, Pavese N, Roncaroli F, Anderson AN, Hammers A, et al. Reference and target region modeling of [11C]-(R)-PK11195 Brain Studies. J Nucl Med. 2007;48:158\u201367.","journal-title":"J Nucl Med"}],"container-title":["Current Neurology and Neuroscience Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11910-013-0405-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11910-013-0405-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11910-013-0405-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,30]],"date-time":"2019-07-30T20:44:17Z","timestamp":1564519457000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11910-013-0405-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,20]]},"references-count":47,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["405"],"URL":"https:\/\/doi.org\/10.1007\/s11910-013-0405-9","relation":{},"ISSN":["1528-4042","1534-6293"],"issn-type":[{"value":"1528-4042","type":"print"},{"value":"1534-6293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,20]]},"article-number":"405"}}