{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:43:09Z","timestamp":1790671389978,"version":"4.1.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Neurol Neurosci Rep"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s11910-018-0816-8","type":"journal-article","created":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T05:28:46Z","timestamp":1517808526000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Neurological Complications of Acute and Chronic Sinusitis"],"prefix":"10.1007","volume":"18","author":[{"given":"Andrea","family":"Ziegler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Patadia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Stankiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,2,5]]},"reference":[{"issue":"3","key":"816_CR1","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1017\/S002221510800234X","volume":"123","author":"S Tandon","year":"2009","unstructured":"Tandon S, Beasley N, Swift AC. Changing trends in intracranial abscesses secondary to ear and sinus disease. J Laryngol Otol. 2009;123(3):283\u20138. https:\/\/doi.org\/10.1017\/S002221510800234X .","journal-title":"J Laryngol Otol"},{"issue":"1","key":"816_CR2","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.amjoto.2008.09.009","volume":"31","author":"JM DelGaudio","year":"2010","unstructured":"\u2022 DelGaudio JM, Evans SH, Sobol SE, Parikh SL. Intracranial complications of sinusitis: what is the role of endoscopic sinus surgery in the acute setting. Am J Otolaryngol. 2010;31(1):25\u20138. Retrospective review of patients with intracranial complications of sinusitis demonstrating the need for combined neurosurgical and rhinological surgical approach. https:\/\/doi.org\/10.1016\/j.amjoto.2008.09.009 .","journal-title":"Am J Otolaryngol"},{"issue":"3","key":"816_CR3","doi-asserted-by":"publisher","first-page":"6","DOI":"10.5604\/00306657.1156326","volume":"69","author":"W Szyfter","year":"2015","unstructured":"Szyfter W, Kruk-Zahajewska A, Bartochowska A, Borucki L. Intracranial complications from sinusitis. Otolaryngol Pol. 2015;69(3):6\u201314. https:\/\/doi.org\/10.5604\/00306657.1156326 .","journal-title":"Otolaryngol Pol"},{"issue":"7","key":"816_CR4","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1097\/00005537-199707000-00005","volume":"107","author":"CM Giannoni","year":"1997","unstructured":"Giannoni CM, Stewart MG, Alford EL. Intracranial complications of sinusitis. Laryngoscope. 1997;107(7):863\u20137. https:\/\/doi.org\/10.1097\/00005537-199707000-00005 .","journal-title":"Laryngoscope"},{"issue":"3","key":"816_CR5","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1288\/00005537-199103000-00003","volume":"101","author":"GL Clayman","year":"1991","unstructured":"Clayman GL, Adams GL, Paugh DR, Koopmann CF. Intracranial complications of paranasal sinusitis: a combined institutional review. Laryngoscope. 1991;101(3):234\u20139. https:\/\/doi.org\/10.1288\/00005537-199103000-00003 .","journal-title":"Laryngoscope"},{"issue":"10","key":"816_CR6","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1017\/S0022215100131731","volume":"109","author":"B Singh","year":"1995","unstructured":"Singh B, Van Dellen J, Ramjettan S, Maharaj TJ. Sinogenic intracranial complications. J Laryngol Otol. 1995;109(10):945\u201350.","journal-title":"J Laryngol Otol"},{"issue":"3","key":"816_CR7","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0030-6665(20)30796-9","volume":"26","author":"JA Stankiewicz","year":"1993","unstructured":"Stankiewicz JA, Newell DJ, Park AH. Complications of inflammatory diseases of the sinuses. Otolaryngol Clin N Am. 1993;26(3):639\u201355.","journal-title":"Otolaryngol Clin N Am"},{"issue":"1","key":"816_CR8","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0030-6665(05)70307-8","volume":"34","author":"AN Goldberg","year":"2001","unstructured":"Goldberg AN, Oroszlan G, Anderson TD. Complications of frontal sinusitis and their management. Otolaryngol Clin N Am. 2001;34(1):211\u201325. https:\/\/doi.org\/10.1016\/S0030-6665(05)70307-8 .","journal-title":"Otolaryngol Clin N Am"},{"issue":"4","key":"816_CR9","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1177\/1457496915622129","volume":"105","author":"TK Nicoli","year":"2016","unstructured":"Nicoli TK, Oinas M, Neimela M, Makitie AA, Atula T. Intracranial Suppurative complications of sinusitis. Scand J Surg. 2016;105(4):254\u201362. https:\/\/doi.org\/10.1177\/1457496915622129 .","journal-title":"Scand J Surg"},{"issue":"6","key":"816_CR10","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1016\/j.ijporl.2015.03.020","volume":"79","author":"AP Patel","year":"2015","unstructured":"Patel AP, Masterson L, Deutsch CJ, Scoffings DJ, Fish BM. Management and outcomes in children with sinogenic intracranial abscesses. Int J Pediatr Otorhinolaryngol. 2015;79(6):868\u201373. Retrospective review of current outcomes in children with sinogenic intracranial abscesses. https:\/\/doi.org\/10.1016\/j.ijporl.2015.03.020 .","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"2","key":"816_CR11","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1097\/INF.0b013e3182748d6e","volume":"32","author":"S Felsenstein","year":"2013","unstructured":"Felsenstein S, Williams B, Shingadia D, Coxon L, Riordan A, Demetriades AK, et al. Clinical and microbiologic features guiding treatment recommendations for brain abscesses in children. Pediatr Infect Dis J. 2013;32(2):129\u201335. https:\/\/doi.org\/10.1097\/INF.0b013e3182748d6e .","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"816_CR12","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1542\/peds.66.4.568","volume":"66","author":"I Brook","year":"1980","unstructured":"Brook I, Friedman EM, Rodriquez WJ, Controni G. Complications of sinusitis in children. Pediatrics. 1980;66(4):568\u201372.","journal-title":"Pediatrics"},{"issue":"5","key":"816_CR13","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1056\/NEJMra1301635","volume":"371","author":"MC Brouwer","year":"2014","unstructured":"Brouwer MC, Tunkel AR, McKhann GM, van de Beek D. Brain abscess. N Engl J Med. 2014;371(5):447\u201356. https:\/\/doi.org\/10.1056\/NEJMra1301635 .","journal-title":"N Engl J Med"},{"issue":"5","key":"816_CR14","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1007\/s13244-015-0424-y","volume":"6","author":"JW Dankbaar","year":"2015","unstructured":"Dankbaar JW, van Bemmel AJ, Pameijer FA. Imaging findings of the orbital and intracranial complications of acute bacterial rhinosinusitis. Insights Imaging. 2015;6(5):509\u201318. https:\/\/doi.org\/10.1007\/s13244-015-0424-y .","journal-title":"Insights Imaging"},{"issue":"9","key":"816_CR15","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1001\/archotol.132.9.969","volume":"132","author":"JA Germiller","year":"2006","unstructured":"Germiller JA, Monin DL, Sparano AM, Tom LW. Intracranial complications of sinusitis in children and adolescents and their outcomes. Arch Otolaryngol Head Neck Surg. 2006;132(9):969\u201376. https:\/\/doi.org\/10.1001\/archotol.132.9.969 .","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"2","key":"816_CR16","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.coms.2012.01.007","volume":"24","author":"J Pierse","year":"2012","unstructured":"Pierse J, Stem A. Benign cysts and tumors of the paranasal sinuses. Oral Maxillofac Surg Clin North Am. 2012;24(2):249\u201364. https:\/\/doi.org\/10.1016\/j.coms.2012.01.007 .","journal-title":"Oral Maxillofac Surg Clin North Am"},{"issue":"9","key":"816_CR17","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1212\/WNL.0000000000000172","volume":"82","author":"MC Brouwer","year":"2014","unstructured":"Brouwer MC, Coutinho JM, van de Beek D. Clinical characteristics and outcome of brain abscess: systemic review and meta-analysis. Neurology. 2014;82(9):806\u201313. https:\/\/doi.org\/10.1212\/WNL.0000000000000172 .","journal-title":"Neurology"},{"issue":"11","key":"816_CR18","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1017\/S0022215100132025","volume":"109","author":"NS Jones","year":"1995","unstructured":"Jones NS, Violaris NS, Chavda SV, Pahor AL. Intracranial complications of sinusitis: the need for aggressive management. J Laryngol Otal. 1995;109(11):1061\u20132.","journal-title":"J Laryngol Otal"},{"issue":"4","key":"816_CR19","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1212\/WNL.38.4.517","volume":"38","author":"SR Levine","year":"1988","unstructured":"Levine SR, Twyman RE, Gilman S. The role of anticoagulation in cavernous sinus thrombosis. Neurology. 1988;38(4):517\u201322. https:\/\/doi.org\/10.1212\/WNL.38.4.517 .","journal-title":"Neurology"},{"issue":"2","key":"816_CR20","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1097\/00005792-198603000-00002","volume":"65","author":"FS Southwick","year":"1986","unstructured":"Southwick FS, Richardson EP, Swartz MN. Septic thrombosis of the dural venous sinuses. Medicine (Baltimore). 1986;65(2):82\u2013106. https:\/\/doi.org\/10.1097\/00005792-198603000-00002 .","journal-title":"Medicine (Baltimore)"},{"issue":"3","key":"816_CR21","first-page":"484","volume":"30","author":"SF Brujin de","year":"1999","unstructured":"de Brujin SF, Stam J. Randomized, placebo-controlled trial of anticoagulant treatment with low-molecular-weight heparin for cerebral sinus thrombosis. Stoke. 1999;30(3):484\u20138.","journal-title":"Stoke."},{"issue":"9","key":"816_CR22","doi-asserted-by":"publisher","first-page":"2085","DOI":"10.1016\/j.joms.2011.09.048","volume":"70","author":"V Desa","year":"2012","unstructured":"\u2022 Desa V, Green R. Cavernous sinus thrombosis: current therapy. J Oral Maxillofac Surg. 2012;70(9):2085\u201391. Comprehensive literature review on the current treatment recommendations for cavernous sinus thrombosis. https:\/\/doi.org\/10.1016\/j.joms.2011.09.048 .","journal-title":"J Oral Maxillofac Surg"},{"issue":"4","key":"816_CR23","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.jaapos.2015.06.001","volume":"19","author":"GS Frank","year":"2015","unstructured":"Frank GS, Smith JM, Davies BW, Mirsky DM, Hink EM, Durairaj VD. Ophthalmic manifestations and outcomes after cavernous sinus thrombosis in children. J AAPOS. 2015;19(4):358\u201362. https:\/\/doi.org\/10.1016\/j.jaapos.2015.06.001 .","journal-title":"J AAPOS."},{"issue":"9","key":"816_CR24","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1258\/002221502760237920","volume":"116","author":"K Bhatia","year":"2002","unstructured":"Bhatia K, Jones NS. Septic cavernous sinus thrombosis secondary to sinusitis: are anticoagulants indicated?: a review of the literature. J Laryngol Otol. 2002;116(9):667\u201376. https:\/\/doi.org\/10.1258\/002221502760237920 .","journal-title":"J Laryngol Otol"},{"issue":"6","key":"816_CR25","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1016\/0002-9394(62)94356-8","volume":"54","author":"OD Solomon","year":"1962","unstructured":"Solomon OD, Moses L, Volk M. Steroid therapy in cavernous sinus thrombosis. Am J Ophthalmol. 1962;54(6):1122\u20134. https:\/\/doi.org\/10.1016\/0002-9394(62)94356-8 .","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"816_CR26","first-page":"105","volume":"39","author":"P Canhao","year":"2008","unstructured":"Canhao P, Cortesao A, Cabral M, Ferro JM, Stam J, Bousser MG, et al. Are steroids useful to treat cerebral venous thrombosis? Stoke. 2008;39(1):105\u201310.","journal-title":"Stoke"},{"issue":"9","key":"816_CR27","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1288\/00005537-197009000-00007","volume":"80","author":"JR Chandler","year":"1970","unstructured":"Chandler JR, Langenbrunner DJ, Stevens ER. The pathogenesis of orbital complications in acute sinusitis. Laryngoscope. 1970;80(9):1414\u201328. https:\/\/doi.org\/10.1288\/00005537-197009000-00007 .","journal-title":"Laryngoscope"},{"issue":"6","key":"816_CR28","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/S1091-8531(98)90033-7","volume":"2","author":"MF Greenberg","year":"1998","unstructured":"Greenberg MF, Pollard ZF. Medical treatment of pediatric subperiosteal orbital abscess secondary to sinusitis. J AAPOS. 1998;2(6):351\u20135. https:\/\/doi.org\/10.1016\/S1091-8531(98)90033-7 .","journal-title":"J AAPOS"},{"key":"816_CR29","first-page":"441","volume":"91","author":"GJ Harris","year":"1993","unstructured":"Harris GJ. Age as a factor in the bacteriology and response to treatment of subperiosteal abscess of the orbit. Trans Am Ophthalmic Soc. 1993;91:441\u2013516.","journal-title":"Trans Am Ophthalmic Soc"},{"issue":"1","key":"816_CR30","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1097\/MOO.0000000000000120","volume":"23","author":"MO Patadia","year":"2015","unstructured":"Patadia MO, Welch KC. Role of immunotherapy in allergic fungal rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg. 2015;23(1):21\u20138. https:\/\/doi.org\/10.1097\/MOO.0000000000000120 .","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"4","key":"816_CR31","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.otohns.2005.11.025","volume":"134","author":"MD Ghegan","year":"2006","unstructured":"Ghegan MD, Lee FS, Schlosser RG. Incidence of skull base and orbital erosion in allergic fungal rhinosinusitis (AFRS) and non-AFRS. Otolaryngol Head Neck Surg. 2006;134(4):592\u20135. https:\/\/doi.org\/10.1016\/j.otohns.2005.11.025 .","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"5","key":"816_CR32","doi-asserted-by":"publisher","first-page":"883","DOI":"10.3171\/jns.2004.100.5.0883","volume":"100","author":"JK Liu","year":"2004","unstructured":"Liu JK, Schaefer SD, Muscatello AL, Couldwell WT. Neurosurgical implications of allergic fungal sinusitis. J Neurosurg. 2004;100(5):883\u201390. https:\/\/doi.org\/10.3171\/jns.2004.100.5.0883 .","journal-title":"J Neurosurg"},{"issue":"2","key":"816_CR33","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1017\/S0022215109991253","volume":"124","author":"MS Marfani","year":"2010","unstructured":"Marfani MS, Jawaid MA, Shaikh SM, Thaheem K. Allergic fungal rhinosinusitis with skull base and orbital erosion. J Laryngal Otol. 2010;124(2):161\u20135. https:\/\/doi.org\/10.1017\/S0022215109991253 .","journal-title":"J Laryngal Otol"},{"issue":"2","key":"816_CR34","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1212\/WNL.26.2.117","volume":"26","author":"TR Hedges","year":"1976","unstructured":"Hedges TR, Leung LS. Parasellar and orbital apex syndrome caused by aspergillosis. Neurology. 1976;26(2):117\u201320. https:\/\/doi.org\/10.1212\/WNL.26.2.117 .","journal-title":"Neurology"},{"issue":"3","key":"816_CR35","doi-asserted-by":"publisher","first-page":"274","DOI":"10.4103\/0028-3886.35689","volume":"55","author":"MS Shamim","year":"2007","unstructured":"Shamim MS, Siddiqui AA, Enam SA, Shah AA, Jooma R, Anwar S. Craniocerebral aspergillosis in immunocompetent hosts: surgical perspective. Neurol India. 2007;55(3):274\u201381.","journal-title":"Neurol India"},{"issue":"5","key":"816_CR36","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.ijporl.2003.12.010","volume":"68","author":"BW Hermann","year":"2004","unstructured":"Hermann BW, Forsen JW. Simultaneous intracranial and orbital complications of acute rhinosinusitis in children. Int J Pediatr Otorhinolaryngol. 2004;68(5):619\u201325. https:\/\/doi.org\/10.1016\/j.ijporl.2003.12.010 .","journal-title":"Int J Pediatr Otorhinolaryngol"}],"container-title":["Current Neurology and Neuroscience Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11910-018-0816-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11910-018-0816-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11910-018-0816-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T22:20:51Z","timestamp":1660429251000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11910-018-0816-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["816"],"URL":"https:\/\/doi.org\/10.1007\/s11910-018-0816-8","relation":{},"ISSN":["1528-4042","1534-6293"],"issn-type":[{"value":"1528-4042","type":"print"},{"value":"1534-6293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"5 February 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"Andrea Ziegler, Monica Patadia, and James Stankiewicz declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article does not contain any studies with human or animal subjects performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}],"article-number":"5"}}