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Perfusion abnormalities in children with cerebral malaria and malarial retinopathy. J Infect Dis. 2009;199(2):263\u201371.","journal-title":"J Infect Dis"},{"key":"1214_CR66","first-page":"672","volume":"23","author":"N Senanayake","year":"1992","unstructured":"Senanayake N, Roman GC. Neurological complications of malaria. S Asian J Trop Med Public Health. 1992;23:672\u201380 Early recognition of post-malarial neurological syndromes including delayed cerebeller ataxia. Further discussion on the subject is provided in References 68\u201371 and References 77 and 79, highlighting nosological issues.","journal-title":"S Asian J Trop Med Public Health"},{"key":"1214_CR67","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1136\/bmj.294.6582.1253","volume":"294","author":"N Senanayake","year":"1987","unstructured":"Senanayake N. Delayed cerebellar ataxia: a new complication of falciparum malaria? BMJ. 1987;294:1253\u20134.\u00a0The first report on the occurrence of delayed cerebeller ataxia following P falciparum malaria.","journal-title":"BMJ"},{"key":"1214_CR68","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1007\/BF00900965","volume":"241","author":"N Senanayake","year":"1994","unstructured":"Senanayake N, de Silva HJ. Delayed cerebellar ataxia complicating falciparum malaria: a clinical study of 74 patients. J Neurol. 1994;241:456\u20139.\u00a0A detailed report on the development of delayed cerebeller ataxia complicating falciparum malaria. The condition has a good prognosis, with spontaneous and complete recovery within 3 months.","journal-title":"J Neurol"},{"key":"1214_CR69","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0140-6736(96)01409-2","volume":"348","author":"NT Hong Mai","year":"1996","unstructured":"Hong Mai NT, Day NP, Chuong LV, Waller D, Phu NH, Bethell DB, et al. Postmalarial neurological syndrome. 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Trop Med Health. 2009;37(3):125\u20138.","journal-title":"Trop Med Health"},{"issue":"5","key":"1214_CR75","first-page":"180","volume":"63","author":"G van derWal","year":"2005","unstructured":"van derWal G, Verhagen WIM, Dofferhoff ASM. Neurological complications following Plasmodium falciparum infection. Neth J Med. 2005;63(5):180\u20133.","journal-title":"Neth J Med"},{"issue":"1","key":"1214_CR76","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1186\/s12936-018-2542-8","volume":"17","author":"Y Tamzali","year":"2018","unstructured":"Tamzali Y, Demeret S, Haddad E, Guillot H, Caumes E, Jaur\u00e9guiberry S. Post-malaria neurological syndrome: four cases, review of the literature and clarification of the nosological framework. Malar J. 2018;17(1):387.\u00a0In this article the authors commented that PMNS is a rare entity encompassing various neurological signs after severe or non-severe malaria appearing after a symptom-free period. PMNS occurred following treatment of malaria with a wide range of anti-malarials.. MRI patterns underline a possible link with acute disseminated encephalomyelitis (ADEM) or auto-immune encephalitis.","journal-title":"Malar J"},{"key":"1214_CR77","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s10156-003-0244-8","volume":"9","author":"T Koibuchi","year":"2003","unstructured":"Koibuchi T, Nakamura T, Miura T, Endo T, Nakamura H, Takahashi T, et al. Acute disseminated encephalomyelitis following Plasmodium vivax malaria. J Infect Chemother. 2003;9:254\u20136.","journal-title":"J Infect Chemother"},{"key":"1214_CR78","first-page":"388","volume":"68","author":"AH Mohsen","year":"2000","unstructured":"Mohsen AH, McKendrick MW, Schmid ML, Green ST. Post-malarial neurological syndrome: a case of acute disseminated encephalomyelitis? J NeurolNeurosurg. Psychiatry. 2000;68:388\u201390.\u00a0In this communication the authors reported the first case of PMNS showing spontaneous and complete resolution of not only the clinical but also the MRI\u00a0abnormalities. There seemed to be no identifiable clinical or radiological features that can distinguish PMNS from ADEM. It was felt that Plasmodium falciparum malaria should therefore be added to the list of infections able to precipitate ADEM.","journal-title":"Psychiatry"},{"key":"1214_CR79","first-page":"473","volume":"21","author":"I Steiner","year":"2015","unstructured":"Steiner I, Kennedy PGE. Acute disseminated encephalomyelitis: current knowledge and open questions. J Neuro-Oncol. 2015;21:473\u20139.","journal-title":"J Neuro-Oncol"},{"key":"1214_CR80","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.tmaid.2018.03.005","volume":"28","author":"J Carreira","year":"2019","unstructured":"Carreira J, Casella MI, Ascen\u00e7\u00e3o BB, Luis NP, Gon\u00e7alves AC, Brito AP, S\u00e1 JE, Parreira M, Lopes D, Po\u00e7as J. Acute disseminated encephalomyelitis, a rare post-malaria neurological complication: case report and review of the literature. Travel Med Infect Dis. 2019;28:81\u20135.\u00a0There are four neurological complications that can occur after malaria treatment at a time when the patient is aparasitaemic: delayed cerebellar ataxia,\u00a0acute inflammatory demyelinating polyneuropathy, post-malaria neurological syndrome and acute disseminated encephalomyelitis (ADEM). In the present series diagnosis of post-malaria ADEM was made based on the acute onset of the neurological symptoms, characteristic findings in magnetic resonance imaging of the brain and prompt response to steroid therapy.","journal-title":"Travel Med Infect Dis"},{"key":"1214_CR81","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/S1607-551X(09)70364-X","volume":"22","author":"CF Hsieh","year":"2006","unstructured":"Hsieh CF, Shih PY, Lin RT. Postmalaria neurological syndrome: a case report. Kaohsiung J Med Sci. 2006;22:630\u20135.","journal-title":"Kaohsiung J Med Sci"},{"key":"1214_CR82","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1212\/WNL.0000000000003414","volume":"87","author":"J Dalmau","year":"2016","unstructured":"Dalmau J. NMDA receptor encephalitis and other antibody-mediated disorders of the synapse: The 2016 Cotzias Lecture. Neurology. 2016;87:2471\u201382.","journal-title":"Neurology."},{"key":"1214_CR83","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.cmi.2017.05.002","volume":"23","author":"A Mailles","year":"2017","unstructured":"Mailles A, Stahl J-P, Bloch KC. Update and new insights in encephalitis. Clin Microbiol Infect. 2017;23:607\u201313.","journal-title":"Clin Microbiol Infect"},{"key":"1214_CR84","doi-asserted-by":"crossref","first-page":"70","DOI":"10.7326\/L16-0651","volume":"167","author":"J Sahuguet","year":"2017","unstructured":"Sahuguet J, Poulet A, Bou Ali H, Parola P, Kaphan E. Post-malaria neurologicsyndrome\u2014autoimmune encephalitis with anti-voltage-gatedpotassium-channel antibodies. Ann Intern Med. 2017;167:70.\u00a0Herein the authors described a patient with PMNS and many features of autoimmune encephalitis who tested positive for VGKC antibodies.","journal-title":"Ann Intern Med"},{"key":"1214_CR85","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1001\/archneur.62.11.1673","volume":"62","author":"T Menge","year":"2005","unstructured":"Menge T, Hemmer B, Nessler S, Wiendl H, Neuhaus O, Hartung H-P, et al. Acute disseminated encephalomyelitis: an update. Arch Neurol. 2005;62:1673\u201380.","journal-title":"Arch Neurol"},{"key":"1214_CR86","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0035-9203(92)90536-L","volume":"86","author":"HJ de Silva","year":"1992","unstructured":"de Silva HJ, Hoang P, Dalton H, de Silva NR, Jewell DP, Peiris JB. Immune activation during cerebellar dysfunction following Plasmodium falciparum malaria. 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Adv Parasitol. 2012;80:151\u2013201 A detailed review of P. vivax infection-related problems and their mechanisms.","journal-title":"Adv Parasitol"},{"key":"1214_CR89","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1086\/654815","volume":"202","author":"BO Carvalho","year":"2010","unstructured":"Carvalho BO, Lopes SCP, Nogueira PA, Orlandi PP, Bargieri DY, Blanco YC, et al. On the cyto-adhesion of Plasmodium vivax\u2014infected erythrocytes. J Infect Dis. 2010;202:638\u201347.","journal-title":"J Infect Dis"},{"key":"1214_CR90","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1111\/j.1708-8305.2009.00349.x","volume":"16","author":"JD Markley","year":"2009","unstructured":"Markley JD, Edmond MB. Post-malaria neurological syndrome: a case report and review of the literature. J Travel Med. 2009;16:424\u201330.","journal-title":"J Travel Med"},{"key":"1214_CR91","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1136\/bmj.292.6533.1430","volume":"292","author":"TVS Arya","year":"1986","unstructured":"Arya TVS, Prasad RN. Falciparum malaria presenting as Guillain-Barre syndrome. BMJ. 1986;292:1430.","journal-title":"BMJ"},{"key":"1214_CR92","first-page":"1338","volume-title":"Peripheral neuropathy","author":"DH Connor","year":"1993","unstructured":"Connor DH, Manz HJ. Parasitic infections of the peripheral nervous system. In: Dyck PJ, Thomas PK, editors. Peripheral neuropathy, vol. 2. Philadelphia: WB Saunders; 1993. p. 1338\u201390."},{"key":"1214_CR93","first-page":"161","volume":"45","author":"SD Drago","year":"1997","unstructured":"Drago SD, Sa ND, Golapalli U, et al. Guillian Barre syndrome in a case of falciparum malaria. 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In this report the authors described detailed histopathological findings found at autopsy in the brain in such cases. Sequestration of parasites in the brain demonstrated two patterns: (a) the \"classic\" appearance (i.e., ring hemorrhages, dense sequestration, and extra-erythrocytic pigment) which was associated with evidence of systemic activation of coagulation and (b) the \"sequestration only\" appearance associated with shorter duration of illness and higher total burden of parasites in all organs including the spleen and gastrointestinal tract.","journal-title":"Front Cell Infect Microbiol"},{"key":"1214_CR98","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0887-8994(96)00115-4","volume":"15","author":"CR Newton","year":"1996","unstructured":"Newton CR, Marsh K, Peshu N, Kirkham FJ. Perturbations of cerebral hemodynamics in Kenyans with cerebral malaria. 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Trans R Soc Trop Med Hyg. 2001;95:618\u201321.","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"1214_CR101","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1136\/pgmj.65.762.236","volume":"65","author":"K Murugavel","year":"1989","unstructured":"Murugavel K, Saravanapavananthan S, Anpalahan A, James RF. Subarachnoid haemorrhage in Plasmodium falciparum malaria. Postgrad Med J. 1989;65:236\u20137.","journal-title":"Postgrad Med J"},{"key":"1214_CR102","first-page":"348","volume":"40","author":"SL Mathur","year":"1992","unstructured":"Mathur SL, Hakim A, Lodha R, Chowdhry P, Jain R. Subarachnoid haemorrhage in falciparum malaria: an unreported presentation. J Assoc Physicians India. 1992;40:348.","journal-title":"J Assoc Physicians India"},{"key":"1214_CR103","first-page":"756","volume":"42","author":"DK Saraswat","year":"1994","unstructured":"Saraswat DK. Case of cerebral malaria presenting as subarachnoid haemorrhage. J Assoc Physicians India. 1994;42:756.","journal-title":"J Assoc Physicians India"},{"key":"1214_CR104","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1056\/NEJM199908193410814","volume":"341","author":"C Gall","year":"1999","unstructured":"Gall C, Spuler A, Fraunberger P. Subarachnoid hemorrhage in a patient with cerebral malaria. N Engl J Med. 1999;341:611\u20133.\u00a0Subarachnoid hemorrhage due to plasmodium infection is very rare, but its incidence may be underestimated.","journal-title":"N Engl J Med"},{"issue":"3","key":"1214_CR105","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1055\/s-0039-1700353","volume":"5","author":"JE Pittella","year":"2014","unstructured":"Pittella JE. Commentary. J Neurosci Rural Pract. 2014;5(3):321\u20132.","journal-title":"J Neurosci Rural Pract"},{"key":"1214_CR106","first-page":"908","volume":"21","author":"AJ Chitkara","year":"1984","unstructured":"Chitkara AJ, Anand NK, Saini L, et al. Indian Pediatr. 1984;21:908\u201319.","journal-title":"Indian Pediatr"},{"key":"1214_CR107","first-page":"227","volume":"44","author":"J Kalita","year":"1996","unstructured":"Kalita J, Dhanuka AK, Misra UK. Cerebeller ataxia in patients with cerebral malaria. Neurol India. 1996;44:227\u20138.\u00a0Cerebeller ataxia associated with acute malaria occurs InIndian and that the features are similar to those described from other parts of the world. This\u00a0neurological complication of falciparum malaria has a good prognosis, resolving completely in virtually all cases.","journal-title":"Neurol India"},{"key":"1214_CR108","first-page":"686","volume":"44","author":"DK Kochar","year":"1996","unstructured":"Kochar DK, Kumawat BL, Kochar SK, et al. Delayed carebellar ataxia \u2013 a complication of Plasmodium falciparum malaria. J Assoc Physicians India. 1996;44:686\u20138.\u00a0Cerebellar ataxia is an unusual post malarial complication. The authors encountered 10 such patients during the malaria epidemic in Rajasthan, India between 1992-1994. All the patients improved within one month without any residual deficit.","journal-title":"J Assoc Physicians India"},{"key":"1214_CR109","first-page":"118","volume":"45","author":"DK Kochar","year":"1997","unstructured":"Kochar DK, Kumawat BL. Cerebeller ataxia in patients of falciparum malaria. Neurol India. 1997;45:118\u20139.","journal-title":"Neurol India"},{"issue":"4","key":"1214_CR110","doi-asserted-by":"publisher","first-page":"taaa051","DOI":"10.1093\/jtm\/taaa051","volume":"27","author":"D Lev","year":"2020","unstructured":"Lev D, Yahalom G, Rabinowicz S, Leshem E, Schwartz E. Opsoclonus-myoclonus as a presentation of post-malaria neurological syndrome. J Travel Med. 2020;27(4):taaa051. https:\/\/doi.org\/10.1093\/jtm\/taaa051.\u00a0Opsoclonus-myoclonus ataxia (OMA) syndrome is rare in children, mostly caused by neuroblastoma. OMA may occur as a very rare complication of falciparum malaria.","journal-title":"J Travel Med"},{"issue":"11","key":"1214_CR111","doi-asserted-by":"crossref","first-page":"852","DOI":"10.4103\/0301-4738.195611","volume":"64","author":"K Bose","year":"2016","unstructured":"Bose K, Saha S, Islam R, et al. Opsoclonus myoclonus ataxia syndrome due to falciparum malaria in two Indian children. Indian J Ophthalmol. 2016;64(11):852\u20134.\u00a0The Opsoclonus-myoclonus syndrome rarely developing in children with falciparum malaria responds well to high dose corticosteroids and intravenous immunoglobulins.","journal-title":"Indian J Ophthalmol"},{"key":"1214_CR112","first-page":"241","volume":"33","author":"AS Puri","year":"1996","unstructured":"Puri AS, Rawal KK, Gupta R, et al. Precipitation of acute intermittent porphyria by chloroquine. 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A trial of aretemether or quinine in children with cerebral malaria. N Engl J Med. 1996;335:69\u201375.\u00a0This trial carried out in Gambia showed that Artemether is as effective as quinine in the treatment of cerebral malaria in children.","journal-title":"N Engl J Med"},{"key":"1214_CR116","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1056\/NEJM199705013361818","volume":"336","author":"LG Muller","year":"1997","unstructured":"Muller LG, Panosian CB. Ataxia and slurred speech after artisunate treatment for falciparum malaria. N Engl J Med. 1997;336:1328.","journal-title":"N Engl J Med"},{"key":"1214_CR117","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S1473-3099(15)00061-4","volume":"15","author":"MM Plucinski","year":"2015","unstructured":"Plucinski MM, Guilavogui T, Sidikiba S, Diakit\u00e9 N, Diakit\u00e9 S, et al. Effect of the ebola-virus-disease epidemic on malaria case management in Guinea, 2014: a crosssectional survey of health facilities. 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Int J Cancer. 2014;134:645\u201353.","journal-title":"Int J Cancer"},{"key":"1214_CR122","first-page":"123","volume":"9","author":"TE Kwenti","year":"2018","unstructured":"Kwenti TE. Malaria and HIV coinfection in sub-Saharan Africa: prevalence, impact, and treatment strategies. Res Rep Trop Med. 2018;9:123\u201336.","journal-title":"Res Rep Trop Med"},{"issue":"2","key":"1214_CR123","first-page":"572","volume":"103","author":"JR Gutman","year":"2020","unstructured":"Gutman JR, Lucchi NW, Cantey PT, Steinhardt LC, et al. Malaria and parasitic neglected tropical diseases: potential syndemics with COVID-19? Am J Trop Med Hyg. 2020;103(2):572\u20137.\u00a0Both malaria and parasitic Neglected Tropical Diseases (NTD) can alter immunologic responses to other infectious agents. Malaria can induce a cytokine\u00a0storm and pro-coagulant state similar to that seen in severe COVID-19. Consequently, co-infections with malaria parasites and SARS-CoV-2 could result\u00a0in substantially worse outcomes than mono-infections with either pathogen, and could shift the age pattern of severe COVID-19 to younger age-groups. Enhancing surveillance platforms could provide signals that indicate whether malaria, NTDs, and COVID-19 have caused syndemics (synergistic epidemics).","journal-title":"Am J Trop Med Hyg"},{"key":"1214_CR124","first-page":"113","volume":"11","author":"BD Akanmori","year":"2000","unstructured":"Akanmori BD, Kurtzhals JA, Goka BQ, Adabayeri V, Ofori MF, Nkrumah FK, Behr C, Hviid L. Distinct patterns of cytokine regulation in discrete clinical forms of Plasmodium falciparum malaria. Eur Cytokine Netw. 2000;11:113\u20138.","journal-title":"Eur Cytokine Netw"},{"key":"1214_CR125","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1042\/BJ20040634","volume":"383","author":"GI Rice","year":"2004","unstructured":"Rice GI, Thomas DA, Grant PJ, Turner AJ, Hooper NM. Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochem J. 2004;383:45\u201351.","journal-title":"Biochem J"},{"key":"1214_CR126","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1186\/s13054-017-1882-z","volume":"21","author":"H Zhang","year":"2017","unstructured":"Zhang H, Baker A. Recombinant human ACE2: acing out angiotensin II in ARDS therapy. Crit Care. 2017;21:305.","journal-title":"Crit Care"},{"key":"1214_CR127","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3389\/fcimb.2015.00103","volume":"5","author":"LS Silva","year":"2016","unstructured":"Silva LS, Silva-Filho JL, Caruso-Neves C, Pinheiro AAS. New concepts in malaria pathogenesis: the role of the renin-angiotensin system. Front Cell Infect Microbiol. 2016;5:103 This article draws attention to a mechanism that might be of much interest during possible co-infection with P. falciparum and the COVID-19 virus.","journal-title":"Front Cell Infect Microbiol"},{"key":"1214_CR128","first-page":"e1005118","volume":"11","author":"T King","year":"2015","unstructured":"King T, Lamb T. Interferon-\u03b3: the Jekyll and Hyde of malaria. PLoSPathog. 2015;11:e1005118.","journal-title":"PLoSPathog."},{"key":"1214_CR129","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2174\/1871526514666140713152858","volume":"14","author":"D Strayer","year":"2014","unstructured":"Strayer D, Dickey R, Carter W. Sensitivity of SARS\/MERS CoV to interferons and other drugs based on achievable serum concentrations in humans. Infect Disord Drug Targets. 2014;14:37\u201343.","journal-title":"Infect Disord Drug Targets"},{"key":"1214_CR130","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1056\/NEJMe2002387","volume":"382","author":"AS Fauci","year":"2020","unstructured":"Fauci AS, Lane HC, Redfeld RR. Covid-19\u2014navigating the uncharted. N Engl J Med. 2020;382:1268\u20139.","journal-title":"N Engl J Med"},{"key":"1214_CR131","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1177\/0961203314546021","volume":"23","author":"LR Gomes","year":"2014","unstructured":"Gomes LR, Martins YC, Ferreira-Da-Cruz MF, Daniel-Ribeiro CT. Autoimmunity, phospholipid-reacting antibodies and malaria immunity. Lupus. 2014;23:1295\u20138.","journal-title":"Lupus."},{"key":"1214_CR132","first-page":"e00301","volume":"86","author":"KL Lokken","year":"1918","unstructured":"Lokken KL, Stull-Lane AR, Poels K, Tsolis RM. Malaria parasite-mediated alteration of macrophage function and increased iron availability predispose to disseminated non-typhoidal Salmonella infection. Infect Immun. 1918;86:e00301\u201318.","journal-title":"Infect Immun"},{"key":"1214_CR133","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1038\/mi.2014.18","volume":"7","author":"JP Mooney","year":"2014","unstructured":"Mooney JP, Butler BP, Lokken KL, Xavier MN, Chau JY, Schaltenberg N, et al. The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection. Mucosal Immunol. 2014;7:1302\u201311.","journal-title":"Mucosal Immunol"},{"key":"1214_CR134","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1093\/infdis\/jis591","volume":"206","author":"MG Thompson","year":"2012","unstructured":"Thompson MG, Breiman RF, Hamel MJ, Desai M, et al. Influenza and malaria coinfection among young children in western Kenya, 2009\u20132011. J Infect Dis. 2012;206:1674\u201384.","journal-title":"J Infect Dis"},{"key":"1214_CR135","doi-asserted-by":"publisher","unstructured":"Klok FA, Kruip MJHA, van der Meer NJM, Arbous MS, Gommers, Damp J, Kant KM, Kaptein FHJ, van Paassen J, Stals MAM, Huisman MV, Endeman H. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020. https:\/\/doi.org\/10.1016\/j.thromres.2020.04.013.\u00a0The incidence of thrombotic complications in ICU patients with COVID-19 infections is remarkably high. The authors reinforce the recommendation to strictly apply pharmacological thrombosis prophylaxis in all COVID-19 patients admitted to the ICU, and are strongly in favor of increasing the prophylaxis towards high-prophylactic doses, even in the absence of randomized evidence.","DOI":"10.1016\/j.thromres.2020.04.013"},{"key":"1214_CR136","doi-asserted-by":"crossref","first-page":"e60","DOI":"10.1056\/NEJMc2009787","volume":"382","author":"TJ Oxley","year":"2020","unstructured":"Oxley TJ, Mocco J, Majidi S, Kellner CP, Shoirah H, Singh IP, De Leacy RA, Shigematsu T, Ladner TR, Yaeger KA, Skliut M, Weinberger J, et al. Large-vessel stroke as a presenting feature of COVID-19 in the young. N Engl J Med. 2020;382:e60.","journal-title":"N Engl J Med"},{"key":"1214_CR137","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.thromres.2013.09.030","volume":"133","author":"P Angchaisuksiri","year":"2014","unstructured":"Angchaisuksiri P. Coagulopathy in malaria. Thromb Res. 2014;133:5\u20139.\u00a0Blood coagulation activation is frequently found in patients with malaria. Clinically apparent bleeding or disseminated intravascular coagulation (DIC) isassociated with very severe disease and a high mortality. Alterations in levels of several coagulation factors have been noted in plasmodium falciparum infections as compared to infections with Plasmodium vivax. It has been demonstrated that severe P. falciparum infection is associated with acute endothelial cell (EC) activation, abnormal circulating ultralarge vWF multimers, and a significant reduction in plasma ADAMTS13 function. These changes may result in intravascular platelet aggregation, thrombocytopenia, and microvascular disease.","journal-title":"Thromb Res"},{"key":"1214_CR138","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0163-4453(03)00130-0","volume":"48","author":"A Krishnan","year":"2004","unstructured":"Krishnan A, Karnad DR, Limaye U, Siddharth W. Cerebral venous and dural sinus thrombosis in severe falciparum malaria. J Infect. 2004;48:86\u201390.\u00a0The diagnosis of cerebral venous sinus thrombosis should be suspected in patients with severe malaria who develop focal neurological deficits along with\u00a0alteration in levels of consciousness. The diagnoses should be confirmed by appropriate imaging; judicious use of local thrombolytic therapy may help\u00a0improve outcome.","journal-title":"J Infect"},{"key":"1214_CR139","first-page":"4","volume":"13","author":"C Musoke","year":"2014","unstructured":"Musoke C, Ssendikadiwa C, Babua C, Schwartz JI. Severe falciparum malaria associated with massive pulmonary embolism. Ann Afr Med. 2014;13:4.\u00a0Microthrombotic complications are the best described in association with Plasmodium falciparum infections. Howevera number of cases of thrombosis involving larger vessels have also been reported..Herein, the authors described the case of a woman with malaria associated with massive pulmonary embolism.","journal-title":"Ann Afr Med"},{"key":"1214_CR140","doi-asserted-by":"crossref","first-page":"100867","DOI":"10.1016\/j.cegh.2021.100867","volume":"12","author":"A Mohan","year":"2021","unstructured":"Mohan A, Wara UU, Amjadh SW, et al. Malaria amidst COVID-19 in India: challenges, efforts, and recommendations. Clin Epidemiol Global Health. 2021;12:100867 An article of much public health importance in the Indian subcontinent and other developing countries with high case loads of both malaria and COVID19.","journal-title":"Clin Epidemiol Global Health"},{"key":"1214_CR141","doi-asserted-by":"publisher","unstructured":"Ritchie H, Ortiz-Ospina E, Beltekian D, et al. Coronavirus pandemic (COVID-19). 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