{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:32:47Z","timestamp":1757705567179},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Oncol Rep"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1007\/s11912-004-0078-2","type":"journal-article","created":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T16:52:08Z","timestamp":1180716728000},"page":"471-475","source":"Crossref","is-referenced-by-count":6,"title":["Endometrial cancer: The management of high-risk disease"],"prefix":"10.1007","volume":"6","author":[{"given":"Gunnar","family":"Kristensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claes","family":"Trop\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"78_CR1","first-page":"45","volume":"6","author":"WT Creasman","year":"2001","unstructured":"Creasman WT, Odicino F, Maisonneuve P, et al.: Carcinoma of the corpus uteri. J Epidemiol Biostat 2001, 6:45\u201386.","journal-title":"J Epidemiol Biostat"},{"key":"78_CR2","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1002\/1097-0142(19901015)60:8+<2035::AID-CNCR2820601515>3.0.CO;2-8","volume":"60","author":"WT Creasman","year":"1987","unstructured":"Creasman WT, Morrow CP, Bundy BN, et al.: Surgical pathologic spread patterns of endometrial cancer: a Gynecologic Oncology Group Study. Cancer 1987, 60:2035\u20132041.","journal-title":"Cancer"},{"key":"78_CR3","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1006\/gyno.1994.1208","volume":"54","author":"BA Goff","year":"1994","unstructured":"Goff BA, Kato D, Schmidt RA, et al.: Uterine papillary serous carcinoma: patterns of metastatic spread. Gynecol Oncol 1994, 54:264\u2013268.","journal-title":"Gynecol Oncol"},{"key":"78_CR4","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1006\/gyno.1999.5505","volume":"74","author":"FD Cirisano","year":"1999","unstructured":"Cirisano FD, Robboy SJ, Dodge RK, et al.: Epidemiologic and surgicopathologic findings of papillary serous and clear cell endometrial cancers when compared to endometrioid carcinoma. Gynecol Oncol 1999, 74:385\u2013394.","journal-title":"Gynecol Oncol"},{"key":"78_CR5","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1002\/(SICI)1097-0142(19961015)78:8<1740::AID-CNCR14>3.0.CO;2-Y","volume":"78","author":"VM Abeler","year":"1996","unstructured":"Abeler VM, Vergote IB, Kj\u00f3rstad KE, et al.: Clear cell carcinoma of the endometrium: prognosis and metastatic pattern. Cancer 1996, 78:1740\u20131747.","journal-title":"Cancer"},{"key":"78_CR6","first-page":"6195","volume":"63","author":"W Wu","year":"2003","unstructured":"Wu W, Slomovitz BM, Celestino J, et al.: Coordinate expression of Cdc25B and ER-alpha is frequent in low-grade endometrioid endometrial carcinoma but uncommon in high-grade endometrioid and nonendometrioid carcinomas. Cancer Res 2003, 63:6195\u20136199.","journal-title":"Cancer Res"},{"key":"78_CR7","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1002\/(SICI)1097-0142(19961101)78:9<1942::AID-CNCR15>3.0.CO;2-Y","volume":"78","author":"B Nordstrom","year":"1996","unstructured":"Nordstrom B, Strang P, Bergstrom R, et al.: A comparison of proliferation markers and heir prognostic value for women with endometrial carcinoma. Ki-67, proliferating cell nuclear antigen, and flow cytometric S-phase fraction. Cancer 1996, 78:1942\u20131951.","journal-title":"Cancer"},{"key":"78_CR8","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1006\/gyno.1998.5192","volume":"71","author":"JP Geisler","year":"1998","unstructured":"Geisler JP, Geisler HE, Wiemann MC, et al.: Lack of bcl-2 persistence: an independent prognostic indicator of poor prognosis in endometrial carcinoma. Gynecol Oncol 1998, 71:305\u2013307.","journal-title":"Gynecol Oncol"},{"key":"78_CR9","first-page":"S31","volume":"8","author":"DA Levine","year":"2002","unstructured":"Levine DA, Hoskins WJ: Update in the management of endometrial cancer. Cancer 2002, 8:S31-S40.","journal-title":"Cancer"},{"key":"78_CR10","first-page":"919","volume-title":"Comprehensive Gynecology","author":"AL Herbst","year":"2001","unstructured":"Herbst AL: Endometrial hyperplasia, endometrial carcinoma, sarcoma: diagnosis and management. In Comprehensive Gynecology, edn 4. Edited by Stenchever MA, Droegemueller W, Herbst AL, et al. St. Louis, MO: Mosby; 2001:919\u2013954. Epidemiologic and surgical pathologic findings of UPSC and CCC when compared with endometroid carcinoma.","edition":"edn 4"},{"key":"78_CR11","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1006\/gyno.2001.6346","volume":"83","author":"A Mariani","year":"2001","unstructured":"Mariani A, Webb MJ, Keeney GL, et al.: Role of wide\/radical hysterectomy and pelvic lymph node dissection in endometrial cancer with cervical involvement. Gynecol Oncol 2001, 83:72\u201380.","journal-title":"Gynecol Oncol"},{"key":"78_CR12","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1046\/j.1525-1438.2001.01061.x","volume":"11","author":"E Sartori","year":"2001","unstructured":"Sartori E, Gadducci A, Landoni F, et al.: Clinical behavior of 203 stage II endometrial cancer cases: the impact of primary surgical approach and of adjuvant radiation therapy. Int J Gynecol Cancer 2001, 11:430\u2013437.","journal-title":"Int J Gynecol Cancer"},{"key":"78_CR13","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1006\/gyno.1999.5501","volume":"74","author":"TL Cornelison","year":"1999","unstructured":"Cornelison TL, Trimble EL, Kosary CL: SEER data, corpus uteri cancer: treatment trends versus survival for FIGO stage II, 1988\u20131994. Gynecol Oncol 1999, 74:350\u2013355.","journal-title":"Gynecol Oncol"},{"key":"78_CR14","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1038\/bjc.1997.313","volume":"75","author":"T Onda","year":"1997","unstructured":"Onda T, Yoshikawa H, Mizutani K, et al.: Treatment of nodepositive endometrial cancer with complete node dissection, chemotherapy and radiation therapy. Br J Cancer 1997, 75:1836\u20131841.","journal-title":"Br J Cancer"},{"key":"78_CR15","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0360-3016(92)90675-8","volume":"24","author":"BW Corn","year":"1992","unstructured":"Corn BW, Lanciano RM, Greven KM, et al.: Endometrial cancer with para-aortic adenopathy: patterns of failure and opportunities for cure. Int J Radiat Oncol Biol Phys 1992, 24:223\u2013227.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"78_CR16","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/gyno.1995.1005","volume":"56","author":"LC Kilgore","year":"1995","unstructured":"Kilgore LC, Partridge EE, Alvarez RD, et al.: Adenocarcinoma of the endometrium: survival comparisons of patients with and without pelvic node sampling. Gynecol Oncol 1995, 56:29\u201333.","journal-title":"Gynecol Oncol"},{"key":"78_CR17","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1006\/gyno.2000.5843","volume":"78","author":"RE Bristow","year":"2000","unstructured":"Bristow RE, Zerbe MJ, Rosenshein NB, et al.: Stage IVB endometrial carcinoma: the role of cytoreductive surgery and determinants of survival. Gynecol Oncol 2000, 78:85\u201391.","journal-title":"Gynecol Oncol"},{"key":"78_CR18","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1006\/gyno.1994.1038","volume":"52","author":"BA Goff","year":"1994","unstructured":"Goff BA, Goodman A, Muntz HG, et al.: Surgical stage IV endometrial carcinoma: a study of 47 cases. Gynecol Oncol 1994, 52:237\u2013240.","journal-title":"Gynecol Oncol"},{"key":"78_CR19","first-page":"419","volume":"56","author":"J Aalders","year":"1980","unstructured":"Aalders J, Abeler V, Kolstad P, et al.: Postoperative external irradiation and prognostic parameters in stage I endometrial carcinoma: clinical and histopathologic study of 540 patients. Obstet Gynecol 1980, 56:419\u2013427.","journal-title":"Obstet Gynecol"},{"key":"78_CR20","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/S0140-6736(00)02139-5","volume":"355","author":"CL Creutzberg","year":"2000","unstructured":"Creutzberg CL, van Putten WL, Koper PC, et al.: Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma. Lancet 2000, 355:1404\u20131411.","journal-title":"Lancet"},{"key":"78_CR21","doi-asserted-by":"crossref","first-page":"3697","DOI":"10.1002\/1097-0142(19930601)71:11<3697::AID-CNCR2820711137>3.0.CO;2-U","volume":"71","author":"KM Greven","year":"1993","unstructured":"Greven KM, Lanciano RM, Corn B, et al.: Pathologic stage III endometrial carcinoma: prognostic factors and patterns of recurrence. Cancer 1993, 71:3697\u20133702.","journal-title":"Cancer"},{"key":"78_CR22","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1006\/gyno.2002.6789","volume":"87","author":"A Mariani","year":"2002","unstructured":"Mariani A, Webb MJ, Keeney GL, et al.: Stage IIIC endometrioid corpus cancer includes distinct subgroups. Gynecol Oncol 2002, 87:112\u2013117.","journal-title":"Gynecol Oncol"},{"key":"78_CR23","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/gyno.1999.5569","volume":"75","author":"G Nelson","year":"1999","unstructured":"Nelson G, Randall M, Sutton G, et al.: FIGO stage IIIC endometrial carcinoma with metastases confined to pelvic lymph nodes: analysis of treatment outcomes, prognostic variables, and failure patterns following adjuvant radiation therapy. Gynecol Oncol 1999, 75:211\u2013214.","journal-title":"Gynecol Oncol"},{"key":"78_CR24","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0360-3016(93)90276-2","volume":"26","author":"ML Hicks","year":"1993","unstructured":"Hicks ML, Piver MS, Puretz JL, et al.: Survival in patients with paraaortic lymph node metastases from endometrial adenocarcinoma clinically limited to the uterus. Int J Radiat Oncol Biol Phys 1993, 26:607\u2013611.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"78_CR25","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0360-3016(92)90676-9","volume":"24","author":"PG Rose","year":"1992","unstructured":"Rose PG, Cha SD, Tak WK, et al.: Radiation therapy for surgically proven para-aortic node metastasis in endometrial carcinoma. Int J Radiat Oncol Biol Phys 1992, 24:229\u2013233.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"78_CR26","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1006\/gyno.1999.5415","volume":"74","author":"PP Connell","year":"1999","unstructured":"Connell PP, Rotmensch J, Waggoner S, et al.: The significance of adnexal involvement in endometrial carcinoma. Gynecol Oncol 1999, 74:74\u201379.","journal-title":"Gynecol Oncol"},{"key":"78_CR27","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1006\/gyno.2001.6189","volume":"82","author":"JB Ashman","year":"2001","unstructured":"Ashman JB, Connell PP, Yamada D, et al.: Outcome of endometrial carcinoma patients with involvement of the uterine serosa. Gynecol Oncol 2001, 82:338\u2013343.","journal-title":"Gynecol Oncol"},{"key":"78_CR28","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1006\/gyno.2000.5849","volume":"78","author":"JL Nicklin","year":"2000","unstructured":"Nicklin JL, Petersen RW: Stage 3B adenocarcinoma of the endometrium: a clinicopathologic study. Gynecol Oncol 2000, 78:203\u2013207.","journal-title":"Gynecol Oncol"},{"key":"78_CR29","first-page":"2","volume":"22","author":"ME Randall","year":"2003","unstructured":"Randall ME, Brunetto VL, Muss H, et al.: Whole abdominal radiotherapy versus combination doxorubicin-cisplatin chemotherapy in advanced endometrial carcinoma: a randomized phase III trial of the Gynecologic Oncology Group [abstract]. Proc ASCO 2003, 22:2. Chemotherapy gives better survival than whole-abdominal radiation in UPSC and CCC tumors.","journal-title":"Proc ASCO"},{"key":"78_CR30","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1200\/JCO.2004.07.184","volume":"22","author":"GF Fleming","year":"2004","unstructured":"Fleming GF, Brunetto VL, Cella D, et al.: Phase III trial of doxorubicin plus cisplatin with or without paclitaxel plus filgrastim in advanced endometrial carcinoma: a Gynecologic Oncology Group Study. J Clin Oncol 2004, 22:2159\u20132166. The role of paclitaxel in patients with advanced or recurrent endometroid, UPSC, and CCC tumors was investigated in this prospective randomized study.","journal-title":"J Clin Oncol"},{"key":"78_CR31","first-page":"535","volume":"85","author":"G Sutton","year":"2002","unstructured":"Sutton G, Bundy B, Axelrod J, et al.: Whole-abdominal radiotherapy in stage I- and II papillary serous (PS) or clear cell cancers of the uterus (a GOG study) [abstract 192]. Gynecol Oncol 2002, 85:535.","journal-title":"Gynecol Oncol"},{"key":"78_CR32","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1006\/gyno.1993.1006","volume":"48","author":"P Rosenberg","year":"1993","unstructured":"Rosenberg P, Boeryd B, Simonsen E: A new aggressive treatment approach to high-grade endometrial cancer of possible benefit to patients with stage I uterine papillary cancer. Gynecol Oncol 1993, 48:32\u201337.","journal-title":"Gynecol Oncol"},{"key":"78_CR33","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1006\/gyno.1993.1308","volume":"51","author":"FV Price","year":"1993","unstructured":"Price FV, Chambers SK, Carcangiu ML, et al.: Intravenous cisplatin, doxorubicin, and cyclophosphamide in the treatment of uterine papillary serous carcinoma (UPSC). Gynecol Oncol 1993, 51:383\u2013389.","journal-title":"Gynecol Oncol"},{"key":"78_CR34","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0090-8258(92)90224-7","volume":"46","author":"C Levenback","year":"1992","unstructured":"Levenback C, Burke TW, Silva E, et al.: Uterine papillary serous carcinoma (UPSC) treated with cisplatin, doxorubicin, and cyclophosphamide (PAC). Gynecol Oncol 1992, 46:317\u2013321.","journal-title":"Gynecol Oncol"}],"container-title":["Current Oncology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11912-004-0078-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11912-004-0078-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11912-004-0078-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T00:31:26Z","timestamp":1559435486000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11912-004-0078-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["78"],"URL":"https:\/\/doi.org\/10.1007\/s11912-004-0078-2","relation":{},"ISSN":["1523-3790","1534-6269"],"issn-type":[{"value":"1523-3790","type":"print"},{"value":"1534-6269","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12]]}}}