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Shernan Holtan has received Research Funding from Incyte Corporation and VITRAC Therapeutics; has received clinical trial adjudication fees from CSL Behring; and has received compensation for service on scientific advisory boards from Generon and Ossium Health. Najla El Jurdi declares that she has no conflict of interest. Anna Prizment declares that she has no conflict of interest. Anne Blaes declares that she has no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article does not contain any studies with human or animal subjects performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}]}}