{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:48:42Z","timestamp":1790419722331,"version":"4.1.0"},"reference-count":109,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T00:00:00Z","timestamp":1475539200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Osteoporos Rep"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s11914-016-0327-y","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T05:53:34Z","timestamp":1475560414000},"page":"269-279","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders"],"prefix":"10.1007","volume":"14","author":[{"given":"Ashkan","family":"Aryaei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Vapniarsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry C.","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyriacos A.","family":"Athanasiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,10,4]]},"reference":[{"key":"327_CR1","doi-asserted-by":"crossref","first-page":"339","DOI":"10.14219\/jada.archive.2006.0183","volume":"137","author":"RJ Gatchel","year":"2006","unstructured":"Gatchel RJ, Stowell AW, Wildenstein L, Riggs R, Ellis E. Efficacy of an early intervention for patients with acute temporomandibular disorder-related pain: a one-year outcome study. J Am Dent Assoc. 2006;137:339\u201347.","journal-title":"J Am Dent Assoc"},{"key":"327_CR2","doi-asserted-by":"crossref","first-page":"25","DOI":"10.14219\/jada.archive.1979.0008","volume":"98","author":"WK Solberg","year":"1979","unstructured":"Solberg WK, Woo MW, Houston JB. Prevalence of mandibular dysfunction in young adults. J Am Dent Assoc. 1979;98:25\u201334.","journal-title":"J Am Dent Assoc"},{"key":"327_CR3","unstructured":"Zarb GA, Carlsson GE. Temporomandibular disorders: osteoarthritis. J Orofac Pain, 1999;13:295\u2013306."},{"key":"327_CR4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1054\/ijom.2001.0175","volume":"31","author":"J-P Loon Van","year":"2002","unstructured":"Van Loon J-P, De Bont L, Stegenga B, Spijkervet F, Verkerke G. Groningen temporomandibular joint prosthesis. Development and first clinical application. Int J Oral Maxillofac Surg. 2002;31:44\u201352.","journal-title":"Int J Oral Maxillofac Surg"},{"key":"327_CR5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.15386\/cjmed-485","volume":"88","author":"AM Chisnoiu","year":"2015","unstructured":"Chisnoiu AM, Picos AM, Popa S, Chisnoiu PD, Lascu L, Picos A, et al. Factors involved in the etiology of temporomandibular disorders\u2014a literature review. Clujul Medical. 2015;88:473.","journal-title":"Clujul Medical"},{"key":"327_CR6","doi-asserted-by":"crossref","first-page":"e393","DOI":"10.11607\/jomi.te20","volume":"28","author":"MK Murphy","year":"2013","unstructured":"Murphy MK, MacBarb RF, Wong ME, Athanasiou KA. Temporomandibular joint disorders: a review of etiology, clinical management, and tissue engineering strategies. Int J Oral Maxillofac Implants. 2013;28:e393.","journal-title":"Int J Oral Maxillofac Implants"},{"key":"327_CR7","first-page":"1","volume":"1","author":"KA Athanasiou","year":"2009","unstructured":"Athanasiou KA, Almarza AJ, Detamore MS, Kalpakci KN. Tissue engineering of temporomandibular joint cartilage. Synth Lect Tissue Eng. 2009;1:1\u2013122.","journal-title":"Synth Lect Tissue Eng"},{"key":"327_CR8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1177\/0022034510381501","volume":"90","author":"K Kalpakci","year":"2011","unstructured":"Kalpakci K, Willard V, Wong M, Athanasiou K. An interspecies comparison of the temporomandibular joint disc. J Dent Res. 2011;90:193\u20138.","journal-title":"J Dent Res"},{"key":"327_CR9","volume-title":"Orthodontic treatment of class III malocclusion","author":"PW Ngan","year":"2014","unstructured":"Ngan PW, Deguchi T, Roberts EW. Orthodontic treatment of class III malocclusion. 2014."},{"key":"327_CR10","first-page":"326","volume":"86","author":"NB Symons","year":"1952","unstructured":"Symons NB. The development of the human mandibular joint. J Anat. 1952;86:326\u201333.","journal-title":"J Anat"},{"key":"327_CR11","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1177\/00220345620410060901","volume":"41","author":"LJ Baume","year":"1962","unstructured":"Baume LJ. Ontogenesis of the human temporomandibular joint. 1. Development of the condyles. J Dent Res. 1962;41:1327\u201339.","journal-title":"J Dent Res"},{"key":"327_CR12","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3109\/00016357709055993","volume":"35","author":"T Hansson","year":"1977","unstructured":"Hansson T, \u00d6berg T, Carlsson GE, Kopp S. Thickness of the soft tissue layers and the articular disk in the temporomandibular joint. Acta Odontol Scand. 1977;35:77\u201383.","journal-title":"Acta Odontol Scand"},{"key":"327_CR13","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0003-9969(93)90142-9","volume":"38","author":"C Bibb","year":"1993","unstructured":"Bibb C, Pullinger A, Baldioceda F. Serial variation in histological character of articular soft tissue in young human adult temporomandibular joint condyles. Arch Oral Biol. 1993;38:343\u201352.","journal-title":"Arch Oral Biol"},{"key":"327_CR14","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0003-9969(97)83718-1","volume":"42","author":"S Roth","year":"1997","unstructured":"Roth S, M\u00fcller K, Fischer D-C, Dannhauer K-H. Specific properties of the extracellular chondroitin sulphate proteoglycans in the mandibular condylar growth centre in pigs. Arch Oral Biol. 1997;42:63\u201376.","journal-title":"Arch Oral Biol"},{"key":"327_CR15","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jbiomech.2008.12.012","volume":"42","author":"M Singh","year":"2009","unstructured":"Singh M, Detamore M. Biomechanical properties of the mandibular condylar cartilage and their relevance to the TMJ disc. J Biomech. 2009;42:405\u201317.","journal-title":"J Biomech"},{"key":"327_CR16","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.joca.2008.07.004","volume":"17","author":"L Wang","year":"2009","unstructured":"Wang L, Lazebnik M, Detamore M. Hyaline cartilage cells outperform mandibular condylar cartilage cells in a TMJ fibrocartilage tissue engineering application. Osteoarthr Cartil. 2009;17:346\u201353.","journal-title":"Osteoarthr Cartil"},{"key":"327_CR17","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1115\/1.1589778","volume":"125","author":"MS Detamore","year":"2003","unstructured":"Detamore MS, Athanasiou KA. Tensile properties of the porcine temporomandibular joint disc. J Biomech Eng. 2003;125:558\u201365.","journal-title":"J Biomech Eng"},{"key":"327_CR18","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.joca.2009.04.025","volume":"17","author":"S Kuroda","year":"2009","unstructured":"Kuroda S, Tanimoto K, Izawa T, Fujihara S, Koolstra J, Tanaka E. Biomechanical and biochemical characteristics of the mandibular condylar cartilage. Osteoarthritis Cartilage. 2009;17:1408\u201315.","journal-title":"Osteoarthritis Cartilage"},{"key":"327_CR19","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.0909-8836.2004.00108.x","volume":"112","author":"M Delatte","year":"2004","unstructured":"Delatte M, Von den Hoff JW, Van Rheden RE, Kuijpers\u2010Jagtman AM. Primary and secondary cartilages of the neonatal rat: the femoral head and the mandibular condyle. Eur J Oral Sci. 2004;112:156\u201362.","journal-title":"Eur J Oral Sci"},{"key":"327_CR20","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1053\/joms.2003.50096","volume":"61","author":"MS Detamore","year":"2003","unstructured":"Detamore MS, Athanasiou KA. Structure and function of the temporomandibular joint disc: implications for tissue engineering. J Oral Maxillofac Surg. 2003;61:494\u2013506.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR21","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1177\/0022034513494817","volume":"92","author":"M Murphy","year":"2013","unstructured":"Murphy M, Arzi B, Hu J, Athanasiou K. Tensile characterization of porcine temporomandibular joint disc attachments. J Dent Res. 2013;92:753\u20138.","journal-title":"J Dent Res"},{"key":"327_CR22","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1834-7819.2005.tb00354.x","volume":"50","author":"J Christo","year":"2005","unstructured":"Christo J, Bennett S, Wilkinson T, Townsend G. Discal attachments of the human temporomandibular joint. Aust Dent J. 2005;50:152\u201360.","journal-title":"Aust Dent J"},{"key":"327_CR23","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.joms.2005.10.009","volume":"64","author":"MS Detamore","year":"2006","unstructured":"Detamore MS, Hegde JN, Wagle RR, Almarza AJ, Montufar-Solis D, Duke PJ, et al. Cell type and distribution in the porcine temporomandibular joint disc. J Oral Maxillofac Surg. 2006;64:243\u20138.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR24","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0278-2391(85)90121-1","volume":"43","author":"GB Wong","year":"1985","unstructured":"Wong GB, Weinberg S, Symington JM. Morphology of the developing articular disc of the human temporomandibular joint. J Oral Maxillofac Surg. 1985;43:565\u20139.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR25","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.matbio.2004.11.006","volume":"24","author":"MS Detamore","year":"2005","unstructured":"Detamore MS, Orfanos JG, Almarza AJ, French MM, Wong ME, Athanasiou KA. Quantitative analysis and comparative regional investigation of the extracellular matrix of the porcine temporomandibular joint disc. Matrix Biol. 2005;24:45\u201357.","journal-title":"Matrix Biol"},{"key":"327_CR26","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1159\/000093969","volume":"182","author":"RP Scapino","year":"2006","unstructured":"Scapino RP, Obrez A, Greising D. Organization and function of the collagen fiber system in the human temporomandibular joint disk and its attachments. Cells Tissues Organs. 2006;182:201\u201325.","journal-title":"Cells Tissues Organs"},{"key":"327_CR27","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0003-9969(00)00045-5","volume":"45","author":"B Berkovitz","year":"2000","unstructured":"Berkovitz B. Collagen crimping in the intra-articular disc and articular surfaces of the human temporomandibular joint. Arch Oral Biol. 2000;45:749\u201356.","journal-title":"Arch Oral Biol"},{"key":"327_CR28","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bjoms.2005.05.002","volume":"44","author":"A Almarza","year":"2006","unstructured":"Almarza A, Bean A, Baggett L, Athanasiou K. Biochemical analysis of the porcine temporomandibular joint disc. Br J Oral Maxillofac Surg. 2006;44:124\u20138.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"327_CR29","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.joca.2005.07.002","volume":"13","author":"M Plumb","year":"2005","unstructured":"Plumb M, Aspden R. The response of elderly human articular cartilage to mechanical stimuli in vitro. Osteoarthritis Cartilage. 2005;13:1084\u201391.","journal-title":"Osteoarthritis Cartilage"},{"key":"327_CR30","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.joms.2013.11.031","volume":"72","author":"M Aoun","year":"2014","unstructured":"Aoun M, Mesnard M, Mon\u00e8de-Hocquard L, Ramos A. Stress analysis of temporomandibular joint disc during maintained clenching using a viscohyperelastic finite element model. J Oral Maxillofac Surg. 2014;72:1070\u20137.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR31","first-page":"9046","volume":"8","author":"M Sun","year":"2015","unstructured":"Sun M, Yang J, Zhou R, Li N, Xia J, Gu F. Mechanical analysis on individualized finite element of temporal-mandibular joint under overlarge jaw opening status. Int J Clin Exp Med. 2015;8:9046.","journal-title":"Int J Clin Exp Med"},{"key":"327_CR32","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1177\/154411130301400207","volume":"14","author":"E Tanaka","year":"2003","unstructured":"Tanaka E, van Eijden T. Biomechanical behavior of the temporomandibular joint disc. Crit Rev Oral Biol. 2003;14:138\u201350.","journal-title":"Crit Rev Oral Biol"},{"key":"327_CR33","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1067\/mpr.2001.118563","volume":"86","author":"AG Pullinger","year":"2001","unstructured":"Pullinger AG, Seligman DA. Multifactorial analysis of differences in temporomandibular joint hard tissue anatomic relationships between disk displacement with and without reduction in women. J Prosthet Dent. 2001;86:407\u201319.","journal-title":"J Prosthet Dent"},{"key":"327_CR34","first-page":"260","volume":"14","author":"M Berger","year":"2015","unstructured":"Berger M, Szalewski L, Bakalczuk M, Bakalczuk G, Bakalczuk S, Szkutnik J. Association between estrogen levels and temporomandibular disorders: a systematic literature review. Przegl menopauzalny\u2009=\u2009Menopause Rev. 2015;14:260\u201370.","journal-title":"Przegl menopauzalny\u2009=\u2009Menopause Rev"},{"key":"327_CR35","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.mehy.2014.12.010","volume":"84","author":"R-Y Bi","year":"2015","unstructured":"Bi R-Y, Ding Y, Gan Y-H. A new hypothesis of sex-differences in temporomandibular disorders: estrogen enhances hyperalgesia of inflamed TMJ through modulating voltage-gated sodium channel 1.7 in trigeminal ganglion? Med Hypotheses. 2015;84:100\u20133.","journal-title":"Med Hypotheses"},{"key":"327_CR36","first-page":"191","volume":"20","author":"DJ Fischer","year":"2006","unstructured":"Fischer DJ, Mueller BA, Critchlow CW, LeResche L. The association of temporomandibular disorder pain with history of head and neck injury in adolescents. J Orofac Pain. 2006;20:191\u20138.","journal-title":"J Orofac Pain"},{"key":"327_CR37","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1179\/crn.2012.018","volume":"30","author":"JM Barrera-Mora","year":"2012","unstructured":"Barrera-Mora JM, Escalona EE, Labruzzi CA, Carrera JML, Ballesteros EJ-C, Reina ES, et al. The relationship between malocclusion, benign joint hypermobility syndrome, condylar position and TMD symptoms. CRANIO\u00ae. 2012;30:121\u201330.","journal-title":"CRANIO\u00ae"},{"key":"327_CR38","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1179\/2151090314Y.0000000013","volume":"33","author":"M Stemig","year":"2015","unstructured":"Stemig M, Myers SL, Kaimal S, Islam MS. Estrogen receptor-alpha polymorphism in patients with and without degenerative disease of the temporomandibular joint. CRANIO\u00ae. 2015;33:129\u201333.","journal-title":"CRANIO\u00ae"},{"key":"327_CR39","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1097\/SCS.0000000000002084","volume":"26","author":"GM Dias","year":"2015","unstructured":"Dias GM, Bonato LL, Guimar\u00e3es JP, Silva JNN, Ferreira LA, Grossmann E, et al. A study of the association between sleep bruxism, low quality of sleep, and degenerative changes of the temporomandibular joint. J Craniofac Surg. 2015;26:2347\u201350.","journal-title":"J Craniofac Surg"},{"key":"327_CR40","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.archoralbio.2011.03.012","volume":"56","author":"CB Meloto","year":"2011","unstructured":"Meloto CB, Serrano PO, Ribeiro-DaSilva MC, Rizzatti-Barbosa CM. Genomics and the new perspectives for temporomandibular disorders. Arch Oral Biol. 2011;56:1181\u201391.","journal-title":"Arch Oral Biol"},{"issue":"4","key":"327_CR41","first-page":"317","volume":"9","author":"TI Suvinen","year":"1995","unstructured":"Suvinen TI, Reade PC. Temporomandibular disorders: a critical review of the nature of pain and its assessment. J Orofac Pain. 1995;9(4):317\u201339.","journal-title":"J Orofac Pain"},{"key":"327_CR42","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1755-7682-1-23","volume":"1","author":"W Jerjes","year":"2008","unstructured":"Jerjes W, Upile T, Abbas S, Kafas P, Vourvachis M, Rob J, et al. Muscle disorders and dentition-related aspects in temporomandibular disorders: controversies in the most commonly used treatment modalities. Int Arch Med. 2008;1:23.","journal-title":"Int Arch Med"},{"key":"327_CR43","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1177\/0022034515574770","volume":"94","author":"X Wang","year":"2015","unstructured":"Wang X, Zhang J, Gan Y, Zhou Y. Current understanding of pathogenesis and treatment of TMJ osteoarthritis. J Dent Res. 2015;94:666\u201373. This short review paper gives a clear and comprehensive understanding on the pathogenesis and current treatment options of TMJ disorders.","journal-title":"J Dent Res"},{"key":"327_CR44","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.tripleo.2008.10.007","volume":"107","author":"GD Klasser","year":"2009","unstructured":"Klasser GD, Greene CS. Oral appliances in the management of temporomandibular disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107:212\u201323.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"327_CR45","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1007\/s10439-009-9659-4","volume":"37","author":"S Ingawal\u00e9","year":"2009","unstructured":"Ingawal\u00e9 S, Goswami T. Temporomandibular joint: disorders, treatments, and biomechanics. Ann Biomed Eng. 2009;37:976\u201396.","journal-title":"Ann Biomed Eng"},{"key":"327_CR46","doi-asserted-by":"publisher","unstructured":"Al-Ani MZ, Davies SJ, Gray RJM, Sloan P, Glenny AM. Stabilisation splint therapy for temporomandibular pain dysfunction syndrome. Cochrane Database Syst Rev. 2004; CD002778. doi: 10.1002\/14651858.CD002778.pub2 .","DOI":"10.1002\/14651858.CD002778.pub2"},{"key":"327_CR47","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.coms.2007.12.005","volume":"20","author":"EV Hersh","year":"2008","unstructured":"Hersh EV, Balasubramaniam R, Pinto A. Pharmacologic management of temporomandibular disorders. Oral Maxillofac Surg Clin North Am. 2008;20:197\u2013210.","journal-title":"Oral Maxillofac Surg Clin North Am"},{"key":"327_CR48","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.cden.2013.04.006","volume":"57","author":"F Liu","year":"2013","unstructured":"Liu F, Steinkeler A. Epidemiology, diagnosis, and treatment of temporomandibular disorders. Dent Clin North Am. 2013;57:465\u201379.","journal-title":"Dent Clin North Am"},{"key":"327_CR49","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.cden.2015.11.012","volume":"60","author":"H Dym","year":"2016","unstructured":"Dym H, Bowler D, Zeidan J. Pharmacologic treatment for temporomandibular disorders. Dent Clin North Am. 2016;60:367\u201379.","journal-title":"Dent Clin North Am"},{"key":"327_CR50","first-page":"CD004715","volume":"10","author":"HR Mujakperuo","year":"2010","unstructured":"Mujakperuo HR, Watson M, Morrison R, Macfarlane TV. Pharmacological interventions for pain in patients with temporomandibular disorders. Cochrane Database Syst Rev. 2010;10:CD004715.","journal-title":"Cochrane Database Syst Rev"},{"key":"327_CR51","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1590\/S2176-94512013000500021","volume":"18","author":"E Machado","year":"2013","unstructured":"Machado E, Bonotto D, Cunali PA. Intra-articular injections with corticosteroids and sodium hyaluronate for treating temporomandibular joint disorders: a systematic review. Dental Press J Orthod. 2013;18:128\u201333.","journal-title":"Dental Press J Orthod"},{"key":"327_CR52","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.joms.2006.02.010","volume":"64","author":"PA Brennan","year":"2006","unstructured":"Brennan PA, Ilankovan V. Arthrocentesis for temporomandibular joint pain dysfunction syndrome. J Oral Maxillofac Surg. 2006;64:949\u201351.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR53","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1053\/joms.2000.8201","volume":"58","author":"WA Carvajal","year":"2000","unstructured":"Carvajal WA, Laskin DM. Long-term evaluation of arthrocentesis for the treatment of internal derangements of the temporomandibular joint. J Oral Maxillofac Surg. 2000;58:852\u20135.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR54","doi-asserted-by":"crossref","first-page":"575","DOI":"10.4317\/medoral.17670","volume":"17","author":"F Monje-Gil","year":"2012","unstructured":"Monje-Gil F, Nitzan D, Gonz\u00e1lez-Garcia R. Temporomandibular joint arthrocentesis. Review of the literature. Med Oral Patol Oral Cir Bucal. 2012;17:575\u201381.","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"327_CR55","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.cden.2011.08.002","volume":"56","author":"H Dym","year":"2012","unstructured":"Dym H, Israel H. Diagnosis and treatment of temporomandibular disorders. Dent Clin North Am. 2012;56:149\u201361.","journal-title":"Dent Clin North Am"},{"key":"327_CR56","doi-asserted-by":"publisher","unstructured":"Rigon M, Pereira LM, Bortoluzzi MC, Loguercio AD, Ramos AL, Cardoso JR. Arthroscopy for temporomandibular disorders. Cochrane Database Syst Rev. 2011; CD006385. doi: 10.1002\/14651858.CD006385.pub2 .","DOI":"10.1002\/14651858CD006385.pub2"},{"key":"327_CR57","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.ijom.2010.01.005","volume":"39","author":"R Elgazzar","year":"2010","unstructured":"Elgazzar R, Abdelhady A, Saad K, Elshaal M, Hussain M, Abdelal S, et al. Treatment modalities of TMJ ankylosis: experience in Delta Nile, Egypt. Int J Oral Maxillofac Surg. 2010;39:333\u201342.","journal-title":"Int J Oral Maxillofac Surg"},{"key":"327_CR58","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1834-7819.2011.01351.x","volume":"56","author":"G Dimitroulis","year":"2011","unstructured":"Dimitroulis G. Temporomandibular joint surgery: what does it mean to the dental practitioner? Aust Dent J. 2011;56:257\u201364.","journal-title":"Aust Dent J"},{"key":"327_CR59","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/joms.2003.50000","volume":"61","author":"JT Reston","year":"2003","unstructured":"Reston JT, Turkelson CM. Meta-analysis of surgical treatments for temporomandibular articular disorders. J Oral Maxillofac Surg. 2003;61:3\u201310.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR60","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1053\/joms.2001.26681","volume":"59","author":"MF Dolwick","year":"2001","unstructured":"Dolwick MF. Disc preservation surgery for the treatment of internal derangements of the temporomandibular joint. J Oral Maxillofac Surg. 2001;59:1047\u201350.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR61","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.joms.2010.07.021","volume":"69","author":"G Dimitroulis","year":"2011","unstructured":"Dimitroulis G. Condylar morphology after temporomandibular joint discectomy with interpositional abdominal dermis-fat graft. J Oral Maxillofac Surg. 2011;69:439\u201346.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR62","doi-asserted-by":"crossref","first-page":"337","DOI":"10.2214\/ajr.151.2.337","volume":"151","author":"P Kaplan","year":"1988","unstructured":"Kaplan P, Ruskin J, Tu H, Knibbe M. Erosive arthritis of the temporomandibular joint caused by Teflon-Proplast implants: plain film features. AJR Am J Roentgenol. 1988;151:337\u20139.","journal-title":"AJR Am J Roentgenol"},{"key":"327_CR63","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0030-4220(87)90302-1","volume":"63","author":"P-L Westesson","year":"1987","unstructured":"Westesson P-L, Eriksson L, Lindstr\u00f6m C. Destructive lesions of the mandibular condyle following discectomy with temporary silicone implant. Oral Surg Oral Med Oral Pathol. 1987;63:143\u201350.","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"327_CR64","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.joms.2006.03.011","volume":"64","author":"G Dimitroulis","year":"2006","unstructured":"Dimitroulis G, Slavin J. Histological evaluation of full thickness skin as an interpositional graft in the rabbit craniomandibular joint. J Oral Maxillofac Surg. 2006;64:1075\u201380.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR65","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0301-0503(81)80034-3","volume":"9","author":"P Bradley","year":"1981","unstructured":"Bradley P, Brockbank J. The temporalis muscle flap in oral reconstruction: a cadaveric, animal and clinical study. J Maxillofac Surg. 1981;9:139\u201345.","journal-title":"J Maxillofac Surg"},{"key":"327_CR66","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.coms.2013.02.008","volume":"25","author":"LG Vega","year":"2013","unstructured":"Vega LG, Gonz\u00e1lez-Garc\u00eda R, Louis PJ. Reconstruction of acquired temporomandibular joint defects. Oral Maxillofac Surg Clin North Am. 2013;25:251\u201369.","journal-title":"Oral Maxillofac Surg Clin North Am"},{"key":"327_CR67","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jobcr.2013.07.003","volume":"3","author":"AJ Sidebottom","year":"2013","unstructured":"Sidebottom AJ. Alloplastic or autogenous reconstruction of the TMJ. J Oral Biol Craniofac Res. 2013;3:135\u20139.","journal-title":"J Oral Biol Craniofac Res"},{"key":"327_CR68","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.ijom.2012.05.032","volume":"41","author":"L Mercuri","year":"2012","unstructured":"Mercuri L. Alloplastic temporomandibular joint replacement: rationale for the use of custom devices. Int J Oral Maxillofac Surg. 2012;41:1033\u201340.","journal-title":"Int J Oral Maxillofac Surg"},{"key":"327_CR69","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1089\/ten.2006.12.969","volume":"12","author":"JC Hu","year":"2006","unstructured":"Hu JC, Athanasiou KA. A self-assembling process in articular cartilage tissue engineering. Tissue Eng. 2006;12:969\u201379.","journal-title":"Tissue Eng"},{"key":"327_CR70","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0022-3468(88)80529-3","volume":"23","author":"JP Vacanti","year":"1988","unstructured":"Vacanti JP, Morse MA, Saltzman WM, Domb AJ, Perez-Atayde A, Langer R. Selective cell transplantation using bioabsorbable artificial polymers as matrices. J Pediatr Surg. 1988;23:3\u20139.","journal-title":"J Pediatr Surg"},{"key":"327_CR71","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1089\/ten.2004.10.1787","volume":"10","author":"AJ Almarza","year":"2004","unstructured":"Almarza AJ, Athanasiou KA. Seeding techniques and scaffolding choice for tissue engineering of the temporomandibular joint disk. Tissue Eng. 2004;10:1787\u201395.","journal-title":"Tissue Eng"},{"key":"327_CR72","doi-asserted-by":"crossref","first-page":"20130287","DOI":"10.1098\/rsif.2013.0287","volume":"10","author":"K Ahtiainen","year":"2013","unstructured":"Ahtiainen K, Mauno J, Ella V, Hagstrom J, Lindqvist C, Miettinen S, et al. Autologous adipose stem cells and polylactide discs in the replacement of the rabbit temporomandibular joint disc. J R Soc Interface. 2013;10:20130287.","journal-title":"J R Soc Interface"},{"key":"327_CR73","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s10439-005-1741-y","volume":"33","author":"MS Detamore","year":"2005","unstructured":"Detamore MS, Athanasiou KA. Evaluation of three growth factors for TMJ disc tissue engineering. Ann Biomed Eng. 2005;33:383\u201390.","journal-title":"Ann Biomed Eng"},{"key":"327_CR74","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.archoralbio.2005.07.002","volume":"51","author":"A Almarza","year":"2006","unstructured":"Almarza A, Athanasiou K. Evaluation of three growth factors in combinations of two for temporomandibular joint disc tissue engineering. Arch Oral Biol. 2006;51:215\u201321.","journal-title":"Arch Oral Biol"},{"key":"327_CR75","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1177\/154405910808700205","volume":"87","author":"K Allen","year":"2008","unstructured":"Allen K, Athanasiou K. Scaffold and growth factor selection in temporomandibular joint disc engineering. J Dent Res. 2008;87:180\u20135.","journal-title":"J Dent Res"},{"key":"327_CR76","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.trsl.2013.11.003","volume":"163","author":"BN Brown","year":"2014","unstructured":"Brown BN, Badylak SF. Extracellular matrix as an inductive scaffold for functional tissue reconstruction. Transl Res. 2014;163:268\u201385.","journal-title":"Transl Res"},{"key":"327_CR77","first-page":"2569","volume":"22","author":"IN Springer","year":"2001","unstructured":"Springer IN, Fleiner B, Jepsen S, A\u00e7il Y. Culture of cells gained from temporomandibular joint cartilage on non-absorbable scaffolds. Biogeosciences. 2001;22:2569\u201377.","journal-title":"Biogeosciences"},{"key":"327_CR78","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1089\/ten.tea.2012.0304","volume":"19","author":"CK Hagandora","year":"2012","unstructured":"Hagandora CK, Gao J, Wang Y, Almarza AJ. Poly (glycerol sebacate): a novel scaffold material for temporomandibular joint disc engineering. Tissue Eng Part A. 2012;19:729\u201337.","journal-title":"Tissue Eng Part A"},{"issue":"7","key":"327_CR79","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1177\/0022034516642404","volume":"95","author":"K Legemate","year":"2016","unstructured":"Legemate K, Tarafder S, Jun Y, Lee C. Engineering human TMJ discs with protein-releasing 3D-printed scaffolds. J Dent Res. 2016;95(7):800\u20137. Paper mimics the structure of the native TMJ disc using 3D printing method. Appropriate growth factors were delivered to MSC cells by encapsulating them in microparticles. The results showed anisotropic scaffold microstructures can be used to fabricate heterogeneous fibrocartilaginous matrix and region-dependent viscoelastic properties similar to the native tissue.","journal-title":"J Dent Res"},{"key":"327_CR80","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/nmat1822","volume":"6","author":"FT Moutos","year":"2007","unstructured":"Moutos FT, Freed LE, Guilak F. A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage. Nat Mater. 2007;6:162\u20137.","journal-title":"Nat Mater"},{"key":"327_CR81","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1089\/ten.2006.12.1183","volume":"12","author":"KD Allen","year":"2006","unstructured":"Allen KD, Athanasiou KA. Tissue engineering of the TMJ disc: a review. Tissue Eng. 2006;12:1183\u201396.","journal-title":"Tissue Eng"},{"key":"327_CR82","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s10439-005-3311-8","volume":"33","author":"AJ Almarza","year":"2005","unstructured":"Almarza AJ, Athanasiou KA. Effects of initial cell seeding density for the tissue engineering of the temporomandibular joint disc. Ann Biomed Eng. 2005;33:943\u201350.","journal-title":"Ann Biomed Eng"},{"key":"327_CR83","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/nrrheum.2014.157","volume":"11","author":"EA Makris","year":"2015","unstructured":"Makris EA, Gomoll AH, Malizos KN, Hu JC, Athanasiou KA. Repair and tissue engineering techniques for articular cartilage. Nat Rev Rheumatol. 2015;11:21\u201334.","journal-title":"Nat Rev Rheumatol"},{"key":"327_CR84","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1089\/ten.2005.11.1188","volume":"11","author":"MS Detamore","year":"2005","unstructured":"Detamore MS, Athanasiou KA. Use of a rotating bioreactor toward tissue engineering the temporomandibular joint disc. Tissue Eng. 2005;11:1188\u201397.","journal-title":"Tissue Eng"},{"key":"327_CR85","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1089\/ten.2006.12.1285","volume":"12","author":"AJ Almarza","year":"2006","unstructured":"Almarza AJ, Athanasiou KA. Effects of hydrostatic pressure on TMJ disc cells. Tissue Eng. 2006;12:1285\u201394.","journal-title":"Tissue Eng"},{"key":"327_CR86","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.archoralbio.2004.01.015","volume":"49","author":"MS Detamore","year":"2004","unstructured":"Detamore MS, Athanasiou KA. Effects of growth factors on temporomandibular joint disc cells. Arch Oral Biol. 2004;49:577\u201383.","journal-title":"Arch Oral Biol"},{"key":"327_CR87","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1023\/B:ABME.0000032454.53116.ee","volume":"32","author":"A Alhadlaq","year":"2004","unstructured":"Alhadlaq A, Elisseeff JH, Hong L, Williams CG, Caplan AI, Sharma B, et al. Adult stem cell driven genesis of human-shaped articular condyle. Ann Biomed Eng. 2004;32:911\u201323.","journal-title":"Ann Biomed Eng"},{"key":"327_CR88","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1089\/ten.2006.0152","volume":"13","author":"L Wang","year":"2007","unstructured":"Wang L, Detamore MS. Tissue engineering the mandibular condyle. Tissue Eng. 2007;13:1955\u201371.","journal-title":"Tissue Eng"},{"key":"327_CR89","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1089\/ten.2006.0150","volume":"13","author":"MM Bailey","year":"2007","unstructured":"Bailey MM, Wang L, Bode CJ, Mitchell KE, Detamore MS. A comparison of human umbilical cord matrix stem cells and temporomandibular joint condylar chondrocytes for tissue engineering temporomandibular joint condylar cartilage. Tissue Eng. 2007;13:2003\u201310.","journal-title":"Tissue Eng"},{"key":"327_CR90","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/jbm.a.31251","volume":"83","author":"GD Nicodemus","year":"2007","unstructured":"Nicodemus GD, Villanueva I, Bryant SJ. Mechanical stimulation of TMJ condylar chondrocytes encapsulated in PEG hydrogels. J Biomed Mater Res A. 2007;83:323\u201331.","journal-title":"J Biomed Mater Res A"},{"key":"327_CR91","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.archoralbio.2006.08.016","volume":"52","author":"Y Chen","year":"2007","unstructured":"Chen Y, Zhang M, Wang J. Study on the effects of mechanical pressure to the ultrastructure and secretion ability of mandibular condylar chondrocytes. Arch Oral Biol. 2007;52:173\u201381.","journal-title":"Arch Oral Biol"},{"key":"327_CR92","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1517\/14712598.2015.1070825","volume":"15","author":"I Gadjanski","year":"2015","unstructured":"Gadjanski I, Vunjak-Novakovic G. Challenges in engineering osteochondral tissue grafts with hierarchical structures. Expert Opin Biol Ther. 2015;15:1583\u201399.","journal-title":"Expert Opin Biol Ther"},{"key":"327_CR93","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/joms.2003.50015","volume":"61","author":"H Abukawa","year":"2003","unstructured":"Abukawa H, Terai H, Hannouche D, Vacanti JP, Kaban LB, Troulis MJ. Formation of a mandibular condyle in vitro by tissue engineering. J Oral Maxillofac Surg. 2003;61:94\u2013100.","journal-title":"J Oral Maxillofac Surg"},{"key":"327_CR94","doi-asserted-by":"crossref","first-page":"3299","DOI":"10.1073\/pnas.0905439106","volume":"107","author":"WL Grayson","year":"2010","unstructured":"Grayson WL, Fr\u00f6hlich M, Yeager K, Bhumiratana S, Chan ME, Cannizzaro C, et al. Engineering anatomically shaped human bone grafts. Proc Natl Acad Sci. 2010;107:3299\u2013304.","journal-title":"Proc Natl Acad Sci"},{"key":"327_CR95","first-page":"346","volume":"35","author":"Y Jiao","year":"2000","unstructured":"Jiao Y, Wang D, Han WL. Effects of various growth factors on human mandibular condylar cartilage cell proliferation. Zhonghua Kou Qiang Yi Xue Za Zhi. 2000;35:346\u20139.","journal-title":"Zhonghua Kou Qiang Yi Xue Za Zhi"},{"key":"327_CR96","doi-asserted-by":"crossref","unstructured":"Hadidi P, Eswaramoorthy R, Hu JC, Athanasiou KA. Tissue and organ regeneration: advances in micro- and nanotechnology. In: Zhang LG, Khademhosseini A, Webster T, editors. The self-assembling process of articular cartilage and self-organization in tissue engineering. Chapter 11. Boca Raton: CRC Press, Taylor and Francis Group; 2014. p. 369\u201393.","DOI":"10.1201\/b15595-14"},{"key":"327_CR97","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1146\/annurev-bioeng-071812-152423","volume":"15","author":"KA Athanasiou","year":"2013","unstructured":"Athanasiou KA, Eswaramoorthy R, Hadidi P, Hu JC. Self-organization and the self-assembling process in tissue engineering. Annu Rev Biomed Eng. 2013;15:115. This review paper explains principles of different scaffold-free approaches that are used in tissue engineering. Self-assembling process as one of the approaches in scaffold-free method has been discussed in detail.","journal-title":"Annu Rev Biomed Eng"},{"key":"327_CR98","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1007\/s10439-008-9572-2","volume":"36","author":"DE Anderson","year":"2008","unstructured":"Anderson DE, Athanasiou KA. Passaged goat costal chondrocytes provide a feasible cell source for temporomandibular joint tissue engineering. Ann Biomed Eng. 2008;36:1992\u20132001.","journal-title":"Ann Biomed Eng"},{"key":"327_CR99","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1177\/154405910808700609","volume":"87","author":"D Johns","year":"2008","unstructured":"Johns D, Wong M, Athanasiou K. Clinically relevant cell sources for TMJ disc engineering. J Dent Res. 2008;87:548\u201352.","journal-title":"J Dent Res"},{"key":"327_CR100","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.archoralbio.2008.09.018","volume":"54","author":"D Anderson","year":"2009","unstructured":"Anderson D, Athanasiou K. A comparison of primary and passaged chondrocytes for use in engineering the temporomandibular joint. Arch Oral Biol. 2009;54:138\u201345.","journal-title":"Arch Oral Biol"},{"key":"327_CR101","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.1089\/ten.tea.2013.0694","volume":"20","author":"RF MacBarb","year":"2014","unstructured":"MacBarb RF, Paschos NK, Abeug R, Makris EA, Hu JC, Athanasiou KA. Passive strain-induced matrix synthesis and organization in shape-specific, cartilaginous neotissues. Tissue Eng Part A. 2014;20:3290\u2013302.","journal-title":"Tissue Eng Part A"},{"key":"327_CR102","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1016\/j.actbio.2010.12.015","volume":"7","author":"KN Kalpakci","year":"2011","unstructured":"Kalpakci KN, Kim EJ, Athanasiou KA. Assessment of growth factor treatment on fibrochondrocyte and chondrocyte co-cultures for TMJ fibrocartilage engineering. Acta Biomater. 2011;7:1710\u20138.","journal-title":"Acta Biomater"},{"key":"327_CR103","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s00441-008-0652-2","volume":"333","author":"D Johns","year":"2008","unstructured":"Johns D, Athanasiou K. Growth factor effects on costal chondrocytes for tissue engineering fibrocartilage. Cell Tissue Res. 2008;333:439\u201347.","journal-title":"Cell Tissue Res"},{"key":"327_CR104","doi-asserted-by":"crossref","first-page":"E4832","DOI":"10.1073\/pnas.1414271111","volume":"111","author":"EA Makris","year":"2014","unstructured":"Makris EA, Responte DJ, Paschos NK, Hu JC, Athanasiou KA. Developing functional musculoskeletal tissues through hypoxia and lysyl oxidase-induced collagen cross-linking. Proc Natl Acad Sci. 2014;111:E4832\u201341.","journal-title":"Proc Natl Acad Sci"},{"key":"327_CR105","doi-asserted-by":"crossref","first-page":"4626","DOI":"10.1016\/j.actbio.2012.09.037","volume":"9","author":"RF MacBarb","year":"2013","unstructured":"MacBarb RF, Makris EA, Hu JC, Athanasiou KA. A chondroitinase-ABC and TGF-\u03b21 treatment regimen for enhancing the mechanical properties of tissue-engineered fibrocartilage. Acta Biomater. 2013;9:4626\u201334. Paper presents the effects of bioactive stimulation and cell ratio on mechanical properties improvement of tissue engineered fibrocartilage. It has been shown the application of both chondroitinase-ABC and TGF-\u03b21 increased the collagen content of treated constructs compared to controls.","journal-title":"Acta Biomater"},{"key":"327_CR106","first-page":"9980","volume":"34","author":"RF MacBarb","year":"2013","unstructured":"MacBarb RF, Chen AL, Hu JC, Athanasiou KA. Engineering functional anisotropy in fibrocartilage neotissues. Biogeosciences. 2013;34:9980\u20139.","journal-title":"Biogeosciences"},{"key":"327_CR107","doi-asserted-by":"crossref","first-page":"20141075","DOI":"10.1098\/rsif.2014.1075","volume":"12","author":"MK Murphy","year":"2015","unstructured":"Murphy MK, Arzi B, Prouty SM, Hu JC, Athanasiou KA. Neocartilage integration in temporomandibular joint discs: physical and enzymatic methods. J R Soc Interface. 2015;12:20141075.","journal-title":"J R Soc Interface"},{"key":"327_CR108","first-page":"6787","volume":"35","author":"EA Makris","year":"2014","unstructured":"Makris EA, MacBarb RF, Paschos NK, Hu JC, Hu JC, Athanasiou KA. Combined use of chondroitinase-ABC, TGF-\u03b21, and collagen crosslinking agent lysyl oxidase to engineer functional neotissues for fibrocartilage repair. Biogeosciences. 2014;35:6787\u201396. Paper demonstrates the combined usage of Chondroitinase-ABC, TGF-\u03b21, and collagen crosslinking agent lysyl oxidase improves mechanical and biochemical properties at higher time points. Followed by in vivo study, authors showed robust integration between the engineered and native tissues using mechanical testing and histology.","journal-title":"Biogeosciences"},{"key":"327_CR109","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1089\/biores.2015.0014","volume":"4","author":"EJ Sheehy","year":"2015","unstructured":"Sheehy EJ, Mesallati T, Kelly L, Vinardell T, Buckley CT, Kelly DJ. Tissue engineering whole bones through endochondral ossification: regenerating the distal phalanx. Biores Open Access. 2015;4:229\u201341.","journal-title":"Biores Open Access"}],"container-title":["Current Osteoporosis Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11914-016-0327-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11914-016-0327-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11914-016-0327-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T03:04:20Z","timestamp":1568430260000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11914-016-0327-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,4]]},"references-count":109,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["327"],"URL":"https:\/\/doi.org\/10.1007\/s11914-016-0327-y","relation":{},"ISSN":["1544-1873","1544-2241"],"issn-type":[{"value":"1544-1873","type":"print"},{"value":"1544-2241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,4]]}}}