{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:40:17Z","timestamp":1791999617745,"version":"4.4.0"},"reference-count":90,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T00:00:00Z","timestamp":1033430400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Science Inc"],"published-print":{"date-parts":[[2002,10]]},"DOI":"10.1007\/s11916-002-0082-x","type":"journal-article","created":{"date-parts":[[2007,6,3]],"date-time":"2007-06-03T03:03:14Z","timestamp":1180839794000},"page":"392-400","source":"Crossref","is-referenced-by-count":47,"title":["Central mechanisms in tension-type headaches"],"prefix":"10.1007","volume":"6","author":[{"given":"M.","family":"Vandenheede","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Schoenen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"82_CR1","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/0895-4356(91)90147-2","volume":"44","author":"BK Rasmussen","year":"1991","unstructured":"Rasmussen BK, Jensen R, Schroll M, et al.: Epidemiology of headache in a general population: a prevalence study. J Clin Epidemiol 1991, 44:1147\u20131157.","journal-title":"J Clin Epidemiol"},{"key":"82_CR2","first-page":"13","volume":"6","author":"Ad Hoc Committee on Classification of Headache","year":"1962","unstructured":"Ad Hoc Committee on Classification of Headache: Classification of Headache. Arch Neurol 1962, 6:13\u201316.","journal-title":"Arch Neurol"},{"key":"82_CR3","first-page":"29","volume":"8","author":"Headache Classification Committee of the International Headache Society","year":"1998","unstructured":"Headache Classification Committee of the International Headache Society: Classification and diagnostic criteria for headache disorders, cranial, and facial pain. Cephalalgia 1998, 8:29\u201334.","journal-title":"Cephalalgia"},{"key":"82_CR4","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0304-3959(93)90131-8","volume":"52","author":"R Jensen","year":"1993","unstructured":"Jensen R, Rasmussen BK, Pedersen B, et al.: Muscle tenderness and pressure pain thresholds in headache. Pain 1993, 52:193\u2013199.","journal-title":"Pain"},{"key":"82_CR5","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1046\/j.1468-2982.1996.1602097.x","volume":"16","author":"R Jensen","year":"1996","unstructured":"Jensen R, Rasmussen BK: Muscular disorders in tension-type headache. Cephalalgia 1996, 16:97\u2013103.","journal-title":"Cephalalgia"},{"key":"82_CR6","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0304-3959(89)90239-X","volume":"38","author":"M Langemark","year":"1989","unstructured":"Langemark M, Jensen K, Jensen TS, et al.: Pressure pain thresholds and thermal nociceptive thresholds in chronic tensiontype headache. Pain 1989, 38:203\u2013210.","journal-title":"Pain"},{"key":"82_CR7","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1001\/archneur.1996.00550040113021","volume":"53","author":"L Bendtsen","year":"1996","unstructured":"Bendtsen L, Jensen R, Olesen J: Decreased pain detection and tolerance thresholds in chronic tension-type headache. Arch Neurol 1996, 53:373\u2013376.","journal-title":"Arch Neurol"},{"key":"82_CR8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0304-3959(92)90258-D","volume":"51","author":"G Bovim","year":"1992","unstructured":"Bovim G: Cervicogenic headache, migraine, and tension-type headache: pressure-pain threshold measurements. Pain 1992, 51:169\u2013173.","journal-title":"Pain"},{"key":"82_CR9","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1046\/j.1526-4610.1998.3801010.x","volume":"38","author":"R Jensen","year":"1998","unstructured":"Jensen R, Bendtsen L, Olesen J: Muscular factors are of importance in tension-type headache. Headache 1998, 38:10\u201317.","journal-title":"Headache"},{"key":"82_CR10","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1046\/j.1468-2982.1987.0704249.x","volume":"7","author":"M Langemark","year":"1987","unstructured":"Langemark M, Olesen J: Pericranial tenderness in tension headache. Cephalalgia 1987, 7:249\u2013255.","journal-title":"Cephalalgia"},{"key":"82_CR11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1046\/j.1468-2982.1995.015003205.x","volume":"15","author":"L Bendsten","year":"1995","unstructured":"Bendsten L, Jensen R, Jensen NK, Olesen J: Pressure-controlled palpation: a new technique which increases the reliability of manual palpation. Cephalalgia 1995, 15:205\u2013210.","journal-title":"Cephalalgia"},{"key":"82_CR12","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0304-3959(95)00114-X","volume":"64","author":"R Jensen","year":"1995","unstructured":"Jensen R: Mechanisms of spontaneous tension-type headaches: an analysis of tenderness, pain thresholds, and EMG. Pain 1995, 64:251\u2013256.","journal-title":"Pain"},{"key":"82_CR13","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0304-3959(95)00239-1","volume":"65","author":"L Bendtsen","year":"1996","unstructured":"Bendtsen L, Jensen R, Olesen J: Qualitatively altered nociception in chronic myofascial pain. Pain 1996, 65:259\u2013264.","journal-title":"Pain"},{"key":"82_CR14","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1002\/art.1780400114","volume":"40","author":"L Bendtsen","year":"1997","unstructured":"Bendtsen L, N\u00f8rregaard J, Jensen R, et al.: Evidence of a qualitatively altered nociception in patients with fibromyalgia. Arthritis Rheum 1997, 40:98\u2013102.","journal-title":"Arthritis Rheum"},{"key":"82_CR15","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0304-3959(94)90076-0","volume":"59","author":"L Bendtsen","year":"1994","unstructured":"Bendtsen L, Jensen R, Jensen NK, et al.: Muscle palpation with controlled finger pressure: new equipment for the study of tender myofascial tissues. Pain 1994, 59:235\u2013239.","journal-title":"Pain"},{"key":"82_CR16","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/0306-4522(90)90265-6","volume":"39","author":"XM Yu","year":"1990","unstructured":"Yu XM, Mense S: Response properties and descending control of rat dorsal horn neurons with deep receptive fields. Neuroscience 1990, 39:823\u2013831.","journal-title":"Neuroscience"},{"key":"82_CR17","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1098\/rstb.1977.0048","volume":"278","author":"PD Wall","year":"1977","unstructured":"Wall PD: The presence of ineffective synapses and the circumstances which unmask them. Phil Trans R Soc Lond Biol 1977, 278:361\u2013372.","journal-title":"Phil Trans R Soc Lond Biol"},{"key":"82_CR18","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/306686a0","volume":"15","author":"CJ Woolf","year":"1983","unstructured":"Woolf CJ: Evidence for a central component of post-injury pain hypersensitivity. Nature 1983, 15:686\u2013688.","journal-title":"Nature"},{"key":"82_CR19","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0304-3959(91)90198-7","volume":"47","author":"J Schoenen","year":"1991","unstructured":"Schoenen J, Bottin D, Hardy F, et al.: Cephalic and extracephalic pressure pain thresholds in chronic tension-type headache. Pain 1991, 47:145\u2013149.","journal-title":"Pain"},{"key":"82_CR20","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1526-4610.1987.hed2701045.x","volume":"27","author":"PD Drummond","year":"1987","unstructured":"Drummond PD: Scalp tenderness and sensitivity to pain in migraine and tension headache. Headache 1987, 27:45\u201350.","journal-title":"Headache"},{"key":"82_CR21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1046\/j.1468-2982.1992.1201033.x","volume":"12","author":"KL Petersen","year":"1992","unstructured":"Petersen KL, Brennum J, Olesen J: Evaluation of pericranial myofascial nociception by pressure algometer: reproducibility and factors of variation. Cephalalgia 1992, 12:33\u201337.","journal-title":"Cephalalgia"},{"key":"82_CR22","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1111\/j.1526-4610.1988.hed2809590.x","volume":"28","author":"M Langemark","year":"1988","unstructured":"Langemark M, Olesen J, Poulsen DL, et al.: Clinical characterization of patients with chronic tension headache. Headache 1988, 28:590\u2013596.","journal-title":"Headache"},{"key":"82_CR23","first-page":"493","volume-title":"The Headaches.","author":"J Olesen","year":"1993","unstructured":"Olesen J, Schoenen J: Tension-type headache, cluster headache, and miscellaneous headaches. In The Headaches. Edited by Olesen J, Tfelt-Hansen P, Welch KMA. New York: Raven Press; 1993:493\u2013496."},{"key":"82_CR24","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0304-3959(96)03188-0","volume":"68","author":"E Kosek","year":"1996","unstructured":"Kosek E, Ekholm J, Hansson P: Sensory dysfunction in fibromyalgia patients with implications for pathogenic mechanisms. Pain 1996, 68:375\u2013383.","journal-title":"Pain"},{"key":"82_CR25","doi-asserted-by":"crossref","first-page":"A258","DOI":"10.1212\/WNL.48.1.258","volume":"48","author":"A Proietti-Cecchini","year":"1997","unstructured":"Proietti-Cecchini A, \u00c1fra J, Maertens de Noordhout A, Schoenen J: Modulation of pressure pain thresholds during isometric contraction in patients with chronic tension-type headache and\/or generalized myofascial pain compared with healthy volunteers. J Neurology 1997, 48:A258.","journal-title":"J Neurology"},{"key":"82_CR26","first-page":"183","volume":"26","author":"WJ Schulte-Mattler","year":"1999","unstructured":"Schulte-Mattler WJ, Wieser T, Zierz S: Treatment of tensiontype headache with botulinum toxin: a pilot study. Eur J Res 1999, 26:183\u2013186.","journal-title":"Eur J Res"},{"key":"82_CR27","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1046\/j.1526-4610.1998.3806468.x","volume":"38","author":"AH Wheeler","year":"1998","unstructured":"Wheeler AH: Botulinum toxin A: adjunctive therapy for refractory headaches associated with pericranial muscle tension. Headache 1998, 38:468\u2013471.","journal-title":"Headache"},{"key":"82_CR28","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1046\/j.1526-4610.2001.041007658.x","volume":"41","author":"W Schmitt","year":"2001","unstructured":"Schmitt W, Slowey E, Fravi N, et al.: Effect of botulinum toxin A injections in the treatment of chronic tension-type headache: a double-blind, placebo-controlled trial. Headache 2001, 41:658\u2013664.","journal-title":"Headache"},{"key":"82_CR29","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1046\/j.1526-4610.2000.00044.x","volume":"40","author":"JD Rollnik","year":"2000","unstructured":"Rollnik JD, Tanneberger O, Schubert M, et al.: Treatment of tension-type headache with botulinum toxin type A: a doubleblind, placebo-controlled study. Headache 2000, 40:300\u2013305.","journal-title":"Headache"},{"key":"82_CR30","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1046\/j.1526-4610.2001.01193.x","volume":"41","author":"JD Rollnik","year":"2001","unstructured":"Rollnik JD, Karst M, Fink M, et al.: Botulinum toxin type A and EMG: a key to the understanding of chronic tension-type headaches? Headache 2001, 41:985\u2013989.","journal-title":"Headache"},{"key":"82_CR31","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/0006-8993(75)90819-7","volume":"85","author":"E Godaux","year":"1975","unstructured":"Godaux E, Desmedt JE: Exteroceptive suppression and motor control of the masseter and temporalis muscles in normal man. Brain Res 1975, 85:447\u2013458.","journal-title":"Brain Res"},{"key":"82_CR32","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1212\/WNL.37.12.1834","volume":"37","author":"J Schoenen","year":"1987","unstructured":"Schoenen J, Jamart B, Gerard P, et al.: Exteroceptive suppression of temporalis muscle activity in chronic headache. Neurology 1987, 37:1834\u20131836.","journal-title":"Neurology"},{"key":"82_CR33","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1046\/j.1468-2982.1991.1103135.x","volume":"11","author":"J Schoenen","year":"1991","unstructured":"Schoenen J, Gerard P, De Pasqua V, et al.: Multiple clinical and paraclinical analyses of chronic tension-type headache associated or unassociated with disorder of pericranial muscles. Cephalalgia 1991, 11:135\u2013139.","journal-title":"Cephalalgia"},{"key":"82_CR34","first-page":"304","volume-title":"Theorie Methodik-Anwenslung bei Kopfschmerz.","author":"H G\u00f6bel","year":"1992","unstructured":"G\u00f6bel H: Schmerzmessung. In Theorie Methodik-Anwenslung bei Kopfschmerz. Stuttgart: Gustav Fischer; 1992:304."},{"key":"82_CR35","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1046\/j.1468-2982.1991.1101023.x","volume":"11","author":"K Nakahima","year":"1991","unstructured":"Nakahima K, Takahashi K: Exteroceptive suppression of the masseter temporalis and trapezius muscles produced by mental nerve stimulation in patients with chronic headaches. Cephalalgia 1991, 11:23\u201328.","journal-title":"Cephalalgia"},{"key":"82_CR36","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1046\/j.1468-2982.1991.1102109.x","volume":"11","author":"TM Wallasch","year":"1991","unstructured":"Wallasch TM, Reinecke M, Langohr HD: EMG analysis of the late exteroceptive suppression period of temporal muscle activity in episodic and chronic tension-type headaches. Cephalalgia 1991, 11:109\u2013112.","journal-title":"Cephalalgia"},{"key":"82_CR37","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1526-4610.1995.hed3506338.x","volume":"35","author":"JA Zwart","year":"1995","unstructured":"Zwart JA, Sand T: Exteroceptive suppression of temporalis muscle activity: a blind study of tension-type headache, migraine, and cervicogenic headache. Headache 1995, 35:338\u2013343.","journal-title":"Headache"},{"key":"82_CR38","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1046\/j.1526-4610.1997.3706368.x","volume":"37","author":"GL Lipchik","year":"1997","unstructured":"Lipchik GL, Holroyd KA, Talbot F, et al.: Pericranial muscle tenderness and exteroceptive suppression of temporalis muscle activity: a blind study of chronic tension-type headache. Headache 1997, 37:368\u2013376.","journal-title":"Headache"},{"key":"82_CR39","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1046\/j.1468-2982.1996.1604251.x","volume":"16","author":"L Bendtsen","year":"1996","unstructured":"Bendtsen L, Jensen R, Brennum J, et al.: Exteroceptive suppression of temporal muscle activity is normal in patients with chronic tension-type headache and not related to actual headache state. Cephalalgia 1996, 16:251\u2013256.","journal-title":"Cephalalgia"},{"key":"82_CR40","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1046\/j.1526-4610.2001.111006142.x","volume":"41","author":"B Aktekin","year":"2001","unstructured":"Aktekin B, Yaltkaya K, Ozkaynak S, et al.: Recovery cycle of the blink reflex and exteroceptive suppression of temporalis muscle activity in migraine and tension-type headache. Headache 2001, 41:142\u2013149.","journal-title":"Headache"},{"key":"82_CR41","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/j.1468-2982.2000.00105.x","volume":"20","author":"GL Lipchik","year":"2000","unstructured":"Lipchik GL, Holroyd KA, O\u2019Donnell FJ, et al.: Exteroceptive suppression periods and pericranial muscle tenderness in chronic tension-type headache: effects of psychopathology, chronicity, and disability. Cephalalgia 2000, 20:638\u2013646.","journal-title":"Cephalalgia"},{"key":"82_CR42","first-page":"91","volume-title":"5-Hydroxytryptamine Mechanisms in Primary Headaches.","author":"J Schoenen","year":"1992","unstructured":"Schoenen J, Sianard-Gaiko J, Raub\u00fcschl O: Serotonin and temporalis exteroceptive silent periods. In 5-Hydroxytryptamine Mechanisms in Primary Headaches. Edited by Olesen J, Saxena PR. New York: Raven Press; 1992:91\u201397."},{"key":"82_CR43","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/0924-980X(96)96532-7","volume":"101","author":"L Bendtsen","year":"1996","unstructured":"Bendtsen L, Jensen R, Olesen J: Amitriptyline, a combined serotonin and noradrenalin re-uptake inhibitor, reduces exteroceptive suppression of temporal muscle activity in patients with chronic tension-type headache. Electroencephalogr Clin Neurophysiol 1996, 101:418\u2013422.","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"82_CR44","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0304-3959(94)90077-9","volume":"59","author":"H G\u00f6bel","year":"1994","unstructured":"G\u00f6bel H, Hamouz V, Hansen C, et al.: Chronic tension-type headache: amitriptyline reduces clinical headache-duration and experimental pain sensitivity but does not alter pericranial muscle activity readings. Pain 1994, 59:241\u2013249.","journal-title":"Pain"},{"key":"82_CR45","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1526-4610.1993.hed3301003.x","volume":"33","author":"J Schoenen","year":"1993","unstructured":"Schoenen J: Exteroceptive suppression of temporalis muscle activity in patients with chronic headache and in normal volunteers: methodology, clinical and pathophysiologic relevance. Headache 1993, 33:3\u201317.","journal-title":"Headache"},{"key":"82_CR46","first-page":"181","volume-title":"Tension-type Headache: Classification, Mechanisms, and Treatment.","author":"J Schoenen","year":"1993","unstructured":"Schoenen J, Lenaerts M, G\u00e9rard P: Inhibition of temporal second exteroceptive suppression produced by single or longlasting electrical stimuli and noxious thermal stimuli in peripheral limbs: effects of Naloxone. In Tension-type Headache: Classification, Mechanisms, and Treatment. Edited by Olesen J, Schoenen J. New York: Raven Press; 1993:181\u2013185."},{"key":"82_CR47","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1046\/j.1468-2982.1993.1303184.x","volume":"13","author":"L Bendtsen","year":"1993","unstructured":"Bendtsen L, Jensen R, Brennum J, et al.: Exteroceptive suppression periods in jaw-closing muscles. Variability and relation to experimental pain and sustained muscle contraction. Cephalalgia 1993, 13:184\u2013191.","journal-title":"Cephalalgia"},{"key":"82_CR48","first-page":"579","volume-title":"The Headaches.","author":"J Schoenen","year":"2000","unstructured":"Schoenen J, Bendtsen L: Neurophysiology of tension-type headache. In The Headaches. Edited by Olesen J, Tfelt-Hansen P, Welch KMA. Philadelphia: Lippincott Williams & Wilkins; 2000:579\u2013587."},{"key":"82_CR49","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1046\/j.1468-2982.1994.1406447.x","volume":"14","author":"T Sand","year":"1994","unstructured":"Sand T, Zwart JA: The blink reflex in chronic tension-type headache migraine and cervicogenic headache. Cephalalgia 1994, 14:447\u2013450.","journal-title":"Cephalalgia"},{"key":"82_CR50","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0006-8993(79)90370-6","volume":"169","author":"RB McCall","year":"1979","unstructured":"McCall RB, Aghajanian GK: Serotoninergic facilitation of facial motorneuron excitation. Brain Res 1979, 169:11\u201327.","journal-title":"Brain Res"},{"key":"82_CR51","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/0168-5597(91)90100-C","volume":"81","author":"G Cruccu","year":"1991","unstructured":"Cruccu G, Pauletti R, Agostino R, et al.: Masseter inhibitory reflex in movement disorders: Huntington\u2019s chorea, Parkinson\u2019s disease, dystonia, and unilateral masticatory spasm. Electroencephalogr Clin Neurophysiol 1991, 81:24\u201330.","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"82_CR52","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1046\/j.1468-2982.1999.1903137.x","volume":"19","author":"F Puca","year":"1999","unstructured":"Puca F, de Tommaso M: Clinical neurophysiology in childhood headache. Cephalalgia 1999, 19:137\u2013146.","journal-title":"Cephalalgia"},{"key":"82_CR53","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0304-3959(00)00465-6","volume":"91","author":"J Ellrich","year":"2001","unstructured":"Ellrich J, Katsarava Z, Przywara S, Kaube H: Is the R3 component of the human blink reflex nociceptive in origin? Pain 2001, 91:389\u2013395.","journal-title":"Pain"},{"key":"82_CR54","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S1388-2457(99)00295-3","volume":"111","author":"H Kaube","year":"2000","unstructured":"Kaube H, Katsarava Z, K\u00e4ufer T, et al.: A new method to increase nociception specificity of the human blink reflex. Clin Neurophysiol 2000, 111:413\u2013416.","journal-title":"Clin Neurophysiol"},{"key":"82_CR55","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-2999(82)90379-X","volume":"78","author":"JC Willer","year":"1982","unstructured":"Willer JC, Roby A, Gerard A, et al.: Electrophysiologic evidence for a possible serotoninergic involvement in some endogenous opiate activity in humans. Eur J Pharmacol 1982, 78:117\u2013120.","journal-title":"Eur J Pharmacol"},{"key":"82_CR56","first-page":"809","volume-title":"Motor Control Mechanisms in Health and Disease.","author":"JC Willer","year":"1983","unstructured":"Willer JC: Nociceptive flexion reflexes as a tool for pain research in man. In Motor Control Mechanisms in Health and Disease. Edited by Desmedt JE. New York: Raven Press; 1983:809\u2013827."},{"key":"82_CR57","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/archneur.1993.00540100056015","volume":"50","author":"M Langemark","year":"1993","unstructured":"Langemark M, Bach FW, Jensen TS, et al.: Decreased nociceptive flexion reflex threshold in chronic tension-type headache. Arch Neurol 1993, 50:1061\u20131064.","journal-title":"Arch Neurol"},{"key":"82_CR58","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1146\/annurev.ph.57.030195.003343","volume":"57","author":"J Garthwaite","year":"1995","unstructured":"Garthwaite J, Boulton CL: Nitric oxide signaling in the central nervous system [Review]. Annu Rev Physiol 1995, 57:683\u2013706.","journal-title":"Annu Rev Physiol"},{"key":"82_CR59","doi-asserted-by":"crossref","first-page":"7008","DOI":"10.1523\/JNEUROSCI.18-17-07008.1998","volume":"18","author":"KO Aley","year":"1998","unstructured":"Aley KO, McCarter G, Levine JD: Nitric oxide signaling in pain and nociceptor sensitization in the rat. J Neurosci 1998, 18:7008\u20137014.","journal-title":"J Neurosci"},{"key":"82_CR60","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1093\/brain\/123.9.1830","volume":"1123","author":"M Ashina","year":"2000","unstructured":"Ashina M, Bendtsen L, Jensen R, et al.: Nitric oxide-induced headache in patients with chronic tension-type headache. Brain 2000, 1123:1830\u20131837.","journal-title":"Brain"},{"key":"82_CR61","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/S0306-4522(98)00536-3","volume":"90","author":"RJ Storer","year":"1999","unstructured":"Storer RJ, Goadsby PJ: Trigeminovascular nociceptive transmission involves N-methyl-D-aspartate and non-N-methyl-D-aspartate glutamate receptors. Neuroscience 1999, 90:1371\u20131376.","journal-title":"Neuroscience"},{"key":"82_CR62","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0304-3959(97)00063-8","volume":"72","author":"J Mao","year":"1997","unstructured":"Mao J, Price DD, Zhu J, et al.: The inhibition of nitric oxideactivated poly (ADP-ribose) synthetase attenuates transynaptic alteration of spinal cord dorsal horn neurons and neuropathic pain in the rat. Pain 1997, 72:355\u2013366.","journal-title":"Pain"},{"key":"82_CR63","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1093\/brain\/122.9.1629","volume":"122","author":"M Ashina","year":"1999","unstructured":"Ashina M, Bendtsen L, Jensen R, et al.: Possible mechanisms of action of nitric oxide synthase inhibitors in chronic tensiontype headache. Brain 1999, 122:1629\u20131635. A nice study that demonstrates the important role of nitric oxide in tension-type headache. It opened a new avenue for research, and suggested that central sensitization can be modulated by treatment with nitric oxide synthase inhibitors.","journal-title":"Brain"},{"key":"82_CR64","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0140-6736(98)01079-4","volume":"353","author":"M Ashina","year":"1999","unstructured":"Ashina M, Lassen LH, Bendtsen L, et al.: Effect of inhibition of nitric oxide synthase on chronic tension-type headache. Lancet 1999, 353:287\u2013289.","journal-title":"Lancet"},{"issue":"63","key":"82_CR65","first-page":"292","volume":"20","author":"M Ashina","year":"2000","unstructured":"Ashina M, Bendtsen L, Jensen R, et al.: Plasma levels of calcitonin gene-related peptide in chronic tension-type headache. Cephalalgia 2000, 20(63):292.","journal-title":"Cephalalgia"},{"key":"82_CR66","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0959-4388(94)90053-1","volume":"4","author":"CJ Woolf","year":"1994","unstructured":"Woolf CJ, Doubell TP: The pathophysiology of chronic painincreased sensitivity to low threshold a beta-fiber inputs. Curr Opin Neurobiol 1994, 4:525\u2013534.","journal-title":"Curr Opin Neurobiol"},{"key":"82_CR67","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0304-3959(93)90161-H","volume":"52","author":"TJ Coderre","year":"1993","unstructured":"Coderre TJ, Katz J, Vaccarino AL, et al.: Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain 1993, 52:259\u2013285.","journal-title":"Pain"},{"key":"82_CR68","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0304-3959(91)90100-C","volume":"44","author":"CJ Woolf","year":"1991","unstructured":"Woolf CJ, Thompson SW: The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of postinjury pain hypersensitivity states. Pain 1991, 44:293\u2013299.","journal-title":"Pain"},{"key":"82_CR69","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1046\/j.1468-2982.2000.00070.x","volume":"20","author":"L Bendtsen","year":"2000","unstructured":"Bendtsen L: Central sensitization in tension-type headache: possible pathophysiologic mechanisms. Cephalalgia 2000, 20:486\u2013508. A good review of the pathophysiology of tension-type headache, concluding that the main problem in chronic tension-type headache is central sensitization that results from prolonged nociceptive inputs from pericranial myofascial tissues. This mechanism is of major importance for the conversion of episodic into chronic tension-type headache.","journal-title":"Cephalalgia"},{"key":"82_CR70","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/j.1526-4610.1993.hed3310528.x","volume":"33","author":"T Nakano","year":"1993","unstructured":"Nakano T, Shimomura T, Takahashi K, et al.: Platelet substance P and 5-hydroxytryptamine in migraine and tension-type headache. Headache 1993, 33:528\u2013532.","journal-title":"Headache"},{"key":"82_CR71","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1046\/j.1526-4610.1997.3709565.x","volume":"37","author":"G Mazzotta","year":"1997","unstructured":"Mazzotta G, Sarchielli P, Gaggioli A, et al.: Study of pressure pain and cellular concentration of neurotransmitters related to nociception in episodic tension-type headache patients. Headache 1997, 37:565\u2013571.","journal-title":"Headache"},{"key":"82_CR72","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0304-3959(99)00159-1","volume":"83","author":"M Ashina","year":"1999","unstructured":"Ashina M, Bendtsen L, Jensen R, et al.: Plasma levels of substance P, neuropeptide Y, and vasoactive intestinal polypeptide in patients with chronic tension-type headache. Pain 1999, 83:541\u2013547.","journal-title":"Pain"},{"key":"82_CR73","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0165-5728(91)90069-J","volume":"32","author":"P Sacerdote","year":"1991","unstructured":"Sacerdote P, Rubboli F, Locatelli L, et al.: Pharmacologic modulation of neuropeptides in peripheral mononuclear cells. J Neuroimmunol 1991, 32:35\u201341.","journal-title":"J Neuroimmunol"},{"key":"82_CR74","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1468-2982.1993.1301003.x","volume":"13","author":"J Schoenen","year":"1993","unstructured":"Schoenen J: Exteroceptive suppression of temporalis muscle activity: methodologic and physiologic aspects. Cephalalgia 1993, 13:3\u201310.","journal-title":"Cephalalgia"},{"key":"82_CR75","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1046\/j.1468-2982.1997.1708843.x","volume":"17","author":"L Bendtsen","year":"1997","unstructured":"Bendtsen L, Jensen R, Hindberg I, et al.: Serotonin metabolism in chronic tension-type headache. Cephalalgia 1997, 17:843\u2013848.","journal-title":"Cephalalgia"},{"key":"82_CR76","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1526-4610.1990.hed3009581.x","volume":"30","author":"T Shimomura","year":"1990","unstructured":"Shimomura T, Takahashi K: Alteration of platelet serotonin in patient with chronic tension-type headache during cold pressor test. Headache 1990, 30:581\u2013583.","journal-title":"Headache"},{"key":"82_CR77","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1136\/jnnp.50.12.1682","volume":"50","author":"R Shulka","year":"1987","unstructured":"Shulka R, Shanker K, Nag D, et al.: Serotonin in tension headache. J Neurol Neurosurg Psychiatry 1987, 50:1682\u20131684.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"82_CR78","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1046\/j.1468-2982.1993.1305346.x","volume":"13","author":"R Leira","year":"1993","unstructured":"Leira R, Castillo J, Martinez F, et al.: Platelet rich plasma serotonin levels in tension-type headache and depression. Cephalalgia 1993, 13:346\u2013348.","journal-title":"Cephalalgia"},{"key":"82_CR79","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1046\/j.1468-2982.1994.014003219.x","volume":"14","author":"R Jensen","year":"1994","unstructured":"Jensen R, Hindberg I: Plasma serotonin increase during episodes of tension-type headache. Cephalalgia 1994, 14:219\u2013222.","journal-title":"Cephalalgia"},{"key":"82_CR80","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0304-3959(95)00020-S","volume":"63","author":"M Langemark","year":"1995","unstructured":"Langemark M, Bach FW, Ekman R, et al.: Increased cerebrospinal fluid met-enkephalin immunoreactivity in patients with chronic tension-type headache. Pain 1995, 63:103\u2013107.","journal-title":"Pain"},{"key":"82_CR81","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0304-3959(92)90257-C","volume":"51","author":"F Bach","year":"1992","unstructured":"Bach F, Langemark M, Secher NH, et al.: Plasma and cerebrospinal fluid b-endorphin in chronic tension-type headache. Pain 1992, 51:163\u2013168.","journal-title":"Pain"},{"key":"82_CR82","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1046\/j.1468-2982.2000.00087.x","volume":"20","author":"L Bendtsen","year":"2000","unstructured":"Bendtsen L, Jensen R: Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache. Cephalalgia 2000, 20:603\u2013610.","journal-title":"Cephalalgia"},{"key":"82_CR83","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1097\/00000542-199511000-00018","volume":"83","author":"JC Eisenach","year":"1995","unstructured":"Eisenach JC, Gebhart GF: Intrathecal amitriptyline acts as an N-methyl-D-aspartate receptor antagonist in the presence of inflammatory hyperalgesia in rats. Anesthesiology 1995, 83:1046\u20131054.","journal-title":"Anesthesiology"},{"key":"82_CR84","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0304-3959(98)00031-1","volume":"76","author":"X Su","year":"1998","unstructured":"Su X, Gebhart GF: Effects of tricyclic antidepressants on mechanosensitive pelvic nerve afferent fibers innervating the rat colon. Pain 1998, 76:105\u2013114.","journal-title":"Pain"},{"key":"82_CR85","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1046\/j.1526-4610.2001.111006063.x","volume":"41","author":"V Piero Di","year":"2001","unstructured":"Di Piero V, Bruti G, Venturi P, et al.: Aminergic tone correlates of migraine and tension-type headache: a study using the tridimensional personality questionnaire. Headache 2001, 41:63\u201371.","journal-title":"Headache"},{"key":"82_CR86","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1526-4610.1994.hed3401020.x","volume":"34","author":"M Langemark","year":"1994","unstructured":"Langemark M, Olesen J: Sulpiride and paroxetine in the treatment of chronic tension-type headache: an explanatory double-blind trial. Headache 1994, 34:20\u201324.","journal-title":"Headache"},{"key":"82_CR87","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0304-3959(91)90066-7","volume":"46","author":"J Olesen","year":"1991","unstructured":"Olesen J: Clinical and pathophysiologic observations in migraine and tension-type headache explained by integration of vascular, supraspinal, and myofascial inputs. Pain 1991, 46:125\u2013132.","journal-title":"Pain"},{"key":"82_CR88","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1046\/j.1468-2982.1999.019004207.x","volume":"19","author":"MB Russell","year":"1999","unstructured":"Russell MB, Ostergaard S, Bendtsen, et al.: Familial occurrence of chronic tension-type headache. Cephalalgia 1999, 19:207\u2013210.","journal-title":"Cephalalgia"},{"key":"82_CR89","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0006-8993(83)91111-3","volume":"22","author":"Y Lamour","year":"1983","unstructured":"Lamour Y, Guilbaud G, Willer JC: Altered properties and laminar distribution of neuronal responses to peripheral stimulation in the SmI cortex of the arthritic rat. Brain Res 1983, 22:183\u2013187.","journal-title":"Brain Res"},{"key":"82_CR90","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0006-8993(81)91174-4","volume":"23","author":"PD Wall","year":"1981","unstructured":"Wall PD, Devor M: The Effect of peripheral nerve injury on dorsal root potentials and on transmission of afferent signals into the spinal cord. Brain Res 1981, 23:95\u2013111.","journal-title":"Brain Res"}],"container-title":["Current Pain and Headache Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11916-002-0082-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11916-002-0082-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11916-002-0082-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T00:34:07Z","timestamp":1559435647000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11916-002-0082-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":90,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["82"],"URL":"https:\/\/doi.org\/10.1007\/s11916-002-0082-x","relation":{},"ISSN":["1531-3433","1534-3081"],"issn-type":[{"value":"1531-3433","type":"print"},{"value":"1534-3081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}