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Cherkalin, Rahman, Edmonds, and Simran Dua declare no conflict of interest. Dr. Shaparin reports research funding with Heron Therapeutics, Averitas Pharma, and AcelRX pharmaceuticals medical. Dr. Koushik has served as a one-time consultant for AcelRX pharmaceuticals. Dr. Gritsenko serves as a consultant for Pacira.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Ethics committee approval was not required as all presented data was obtained via literature search. This study was performed in accordance with the Helsinki Declaration of 1964 and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}