{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:17:01Z","timestamp":1790979421475,"version":"4.1.0"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Pain Headache Rep"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose of Review<\/jats:title>\n                <jats:p>Cryoneurolysis refers to the process of reversibly ablating peripheral nerves with extremely cold temperatures to provide analgesia for weeks to months. With ultrasound-guidance or landmark-based techniques, it is an effective modality for managing both acute and chronic pain. In this review, we summarize the reported literature behind its potential applications and efficacy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Recent Findings<\/jats:title>\n                <jats:p>Here, we summarize several studies (from case reports to clinical trials) describing the use of ultrasound-guided and landmark-based cryoneurolysis for acute and chronic pain. Acute pain indications included pain related to knee arthroplasty, limb amputations, mastectomies, shoulder surgery, rib fractures, and burn. Chronic pain indications included chronic knee pain (due to osteoarthritis), shoulder pain, painful neuropathies, postmastectomy pain syndrome, phantom limb pain, facial pain\/headaches, foot\/ankle pain, inguinal pain, and sacroiliac joint pain.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Summary<\/jats:title>\n                <jats:p>For both acute and chronic pain indications, more high quality randomized controlled clinical trials are needed to definitively assess the efficacy of cryoneurolysis versus other standard therapies for a multitude of pain conditions.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11916-024-01281-z","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T14:02:20Z","timestamp":1720101740000},"page":"1097-1104","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["A Narrative Review of Ultrasound-Guided and Landmark-based Percutaneous Cryoneurolysis for the Management of Acute and Chronic Pain"],"prefix":"10.1007","volume":"28","author":[{"given":"Rodney A.","family":"Gabriel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eri C.","family":"Seng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian P.","family":"Curran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Winston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea M.","family":"Trescot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Filipovski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,4]]},"reference":[{"issue":"2","key":"1281_CR1","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1111\/papr.13182","volume":"23","author":"E Biel","year":"2023","unstructured":"Biel E, Aroke EN, Maye J, et al. The applications of cryoneurolysis for acute and chronic pain management. Pain Pract. 2023;23(2):204\u201315. https:\/\/doi.org\/10.1111\/papr.13182","journal-title":"Pain Pract"},{"issue":"6","key":"1281_CR2","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1080\/17434440.2021.1927705","volume":"18","author":"IVJJ Finneran","year":"2021","unstructured":"Finneran IVJJ, Ilfeld BM. Percutaneous cryoneurolysis for acute pain management: current status and future prospects. Expert Rev Med Dev. 2021;18(6):533\u201343. https:\/\/doi.org\/10.1080\/17434440.2021.1927705","journal-title":"Expert Rev Med Dev"},{"key":"1281_CR3","doi-asserted-by":"publisher","unstructured":"*Ilfeld BM, Finneran JJ. Cryoneurolysis and Percutaneous Peripheral Nerve Stimulation to Treat Acute Pain. Anesthesiology. 2020;133(5):1127\u20131149, https:\/\/doi.org\/10.1097\/aln.0000000000003532This is a more recent comprehensive review article including cryoneurolysis and its application in acute surgical pain","DOI":"10.1097\/aln.0000000000003532"},{"key":"1281_CR4","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-024-01222-w","author":"DL Chang","year":"2024","unstructured":"Chang DL, Mirman B, Mehta N, et al. Applications of Cryoneurolysis in Chronic Pain Management: a review of the current literature. Curr Pain Headache Rep. 2024. https:\/\/doi.org\/10.1007\/s11916-024-01222-w","journal-title":"Curr Pain Headache Rep"},{"issue":"1","key":"1281_CR5","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1515\/sjpain-2019-0086","volume":"20","author":"G Kvarstein","year":"2019","unstructured":"Kvarstein G, H\u00f6gstr\u00f6m H, Allen SM, et al. Cryoneurolysis for cervicogenic headache \u2013 a double blinded randomized controlled study. 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Dr. Gabriel\u2019s institution serves as a consultant for Avanos, which Dr. Gabriel represents. Dr. Trescot has served on an advisory board for Atricure, (Mason, OH) and is the Chief Medical Officer for Stimwave Technologies (Pompano, FL). Paul Winston has received educational grants and honoraria from AbbVie, Ipsen, Merz, and Pacira Biosciences.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statements and Declarations"}},{"value":"Dr. Gabriel\u2019s institution received funding for research from Epimed, Teleflex, Merck, Takeda, and SPR Therapeutics. Dr. Gabriel\u2019s institution serves as a consultant for Avanos, which Dr. Gabriel represents. Dr. Trescot has served on an advisory board for Atricure, (Mason, OH) and is the Chief Medical Officer for Stimwave Technologies (Pompano, FL). Paul Winston has received educational grants and honoraria from AbbVie, Ipsen, Merz, and Pacira Biosciences.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}