{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T12:13:48Z","timestamp":1765800828690,"version":"3.48.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Pain Headache Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11916-025-01453-5","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T12:10:25Z","timestamp":1765800625000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Efficacy and Safety of Serratus Anterior Plane Block for Pain Management in Patients with Rib Fractures: a Narrative Review"],"prefix":"10.1007","volume":"30","author":[{"given":"Alan D.","family":"Kaye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmine J.","family":"Fagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Austin S.","family":"Thomassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"Leon C.","family":"LaHaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabrielle A.","family":"Cassagne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Ardoin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles J.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahab","family":"Ahmadzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Heisler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Drinkard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahar","family":"Shekoohi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"issue":"1","key":"1453_CR1","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.bjane.2018.04.005","volume":"69","author":"FCDO Camacho","year":"2019","unstructured":"Camacho FCDO, Segura-Grau E. Continuous serratus anterior plane block provides analgesia in multiple rib fractures: a case report. Braz J Anesthesiol Engl Ed. 2019;69(1):87\u201390. https:\/\/doi.org\/10.1016\/j.bjane.2018.04.005.","journal-title":"Braz J Anesthesiol Engl Ed"},{"key":"1453_CR2","doi-asserted-by":"publisher","first-page":"59","DOI":"10.2147\/LRA.S207791","volume":"12","author":"N Hernandez","year":"2019","unstructured":"Hernandez N, De Haan J, Clendenin D, et al. Impact of serratus plane block on pain scores and incentive spirometry volumes after chest trauma. Local Reg Anesth. 2019;12:59\u201366. https:\/\/doi.org\/10.2147\/LRA.S207791.","journal-title":"Local Reg Anesth"},{"key":"1453_CR3","unstructured":"Kuo K, Kim AM. Rib Fracture. In: StatPearls [Internet]. StatPearls Publishing; 2023. Accessed November 18, 2024. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541020\/"},{"key":"1453_CR4","unstructured":"Southgate SJ, River GF, Herbst MK. Ultrasound-Guided Serratus Anterior Blocks. In: StatPearls. StatPearls Publishing; 2024. Accessed November 19, 2024. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538476\/"},{"issue":"3","key":"1453_CR5","doi-asserted-by":"publisher","first-page":"411","DOI":"10.4103\/joacp.JOACP_349_19","volume":"37","author":"S Diwan","year":"2021","unstructured":"Diwan S, Nair A. A retrospective study comparing the analgesic efficacy of ultrasound-guided serratus anterior plane block versus intravenous fentanyl infusion in patients with multiple rib fractures. J Anaesthesiol Clin Pharmacol. 2021;37(3):411\u20135. https:\/\/doi.org\/10.4103\/joacp.JOACP_349_19.","journal-title":"J Anaesthesiol Clin Pharmacol"},{"issue":"2","key":"1453_CR6","doi-asserted-by":"publisher","first-page":"104","DOI":"10.4103\/0019-5049.79875","volume":"55","author":"G Kuthiala","year":"2011","unstructured":"Kuthiala G, Chaudhary G. Ropivacaine: a review of its pharmacology and clinical use. Indian J Anaesth. 2011;55(2):104. https:\/\/doi.org\/10.4103\/0019-5049.79875.","journal-title":"Indian J Anaesth"},{"issue":"1","key":"1453_CR7","doi-asserted-by":"publisher","first-page":"e001183","DOI":"10.1136\/tsaco-2023-001183","volume":"9","author":"V Sadauskas","year":"2024","unstructured":"Sadauskas V, Fofana M, Brunson D, et al. Serratus anterior plane block improves pain and incentive spirometry volumes in trauma patients with multiple rib fractures: a prospective cohort study. Trauma Surg Acute Care Open. 2024;9(1):e001183. https:\/\/doi.org\/10.1136\/tsaco-2023-001183.","journal-title":"Trauma Surg Acute Care Open"},{"issue":"6","key":"1453_CR8","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/j.annemergmed.2017.04.011","volume":"70","author":"CE Murphy","year":"2017","unstructured":"Murphy CE, Raja AS, Baumann BM, et al. Rib fracture diagnosis in the panscan era. Ann Emerg Med. 2017;70(6):904\u20139. https:\/\/doi.org\/10.1016\/j.annemergmed.2017.04.011.","journal-title":"Ann Emerg Med"},{"issue":"7","key":"1453_CR9","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1001\/jamasurg.2024.0969","volume":"159","author":"C Partyka","year":"2024","unstructured":"Partyka C, Asha S, Berry M, et al. Serratus anterior plane blocks for early rib fracture pain management: the SABRE randomized clinical trial. JAMA Surg. 2024;159(7):810\u20137. https:\/\/doi.org\/10.1001\/jamasurg.2024.0969.","journal-title":"JAMA Surg"},{"key":"1453_CR10","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.2147\/JPR.S258443","volume":"13","author":"X Li","year":"2020","unstructured":"Li X, Liu Y, Zhao J, Xiang Z, Ren C, Qiao K. The safety and efficacy of ultrasound-guided serratus anterior plane block (SAPB) combined with dexmedetomidine for patients undergoing video-assisted thoracic surgery (VATS): a randomized controlled trial. J Pain Res. 2020;13:1785. https:\/\/doi.org\/10.2147\/JPR.S258443.","journal-title":"J Pain Res"},{"issue":"1","key":"1453_CR11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1002\/anr3.12034","volume":"8","author":"M Desai","year":"2020","unstructured":"Desai M, Narayanan MK, Venkataraju A. Pneumothorax following serratus anterior plane block. Anaesth Rep. 2020;8(1):14. https:\/\/doi.org\/10.1002\/anr3.12034.","journal-title":"Anaesth Rep"},{"issue":"S1","key":"1453_CR12","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/anae.15282","volume":"76","author":"AJR Macfarlane","year":"2021","unstructured":"Macfarlane AJR, Gitman M, Bornstein KJ, El-Boghdadly K, Weinberg G. Updates in our understanding of local anesthetic systemic toxicity: a narrative review. Anaesthesia. 2021;76(S1):27\u201339. https:\/\/doi.org\/10.1111\/anae.15282.","journal-title":"Anaesthesia"},{"issue":"7","key":"1453_CR13","doi-asserted-by":"publisher","first-page":"614","DOI":"10.4103\/ija.ija_844_21","volume":"67","author":"S Singh","year":"2023","unstructured":"Singh S, Avinash R, Jaiswal S, Kumari A. Comparison of safety and efficacy of thoracic epidural block and erector spinae plane block for analgesia in patients with multiple rib fractures: a pilot single-blinded, randomised controlled trial. Indian J Anaesth. 2023;67(7):614\u20139. https:\/\/doi.org\/10.4103\/ija.ija_844_21.","journal-title":"Indian J Anaesth"},{"key":"1453_CR14","doi-asserted-by":"publisher","first-page":"59","DOI":"10.2147\/LRA.S207791","volume":"12","author":"N Hernandez","year":"2019","unstructured":"Hernandez N, de Haan J, Clendeninn D, et al. Impact of serratus plane block on pain scores and incentive spirometry volumes after chest trauma. Local Reg Anesth. 2019;12:59\u201366. https:\/\/doi.org\/10.2147\/LRA.S207791.","journal-title":"Local Reg Anesth"},{"key":"1453_CR15","doi-asserted-by":"publisher","unstructured":"Regional anaesthesia for rib fractures: too many choices, too little evidence - El-Boghdadly \u2013\u20092019 - Anaesthesia - Wiley Online Library. Accessed November 25. 2024. https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/https:\/\/doi.org\/10.1111\/anae.14634","DOI":"10.1111\/anae.14634"},{"key":"1453_CR16","doi-asserted-by":"crossref","unstructured":"Rib fracture management | BJA Education | Oxford Academic. Accessed November 25. 2024. https:\/\/academic.oup.com\/bjaed\/article\/16\/1\/26\/2463139","DOI":"10.1093\/bjaceaccp\/mkv011"},{"issue":"2 Suppl","key":"1453_CR17","doi-asserted-by":"publisher","first-page":"S105","DOI":"10.36076\/ppj.2008\/11\/S105","volume":"11","author":"R Benyamin","year":"2008","unstructured":"Benyamin R, Trescot AM, Datta S, et al. Opioid complications and side effects. Pain Physician. 2008;11(2 Suppl):S105\u2013120.","journal-title":"Pain Physician"},{"key":"1453_CR18","unstructured":"Southgate SJ, River GF, Herbst MK. Ultrasound-Guided Serratus Anterior Blocks. In: StatPearls. StatPearls Publishing; 2024. Accessed November 25, 2024. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538476\/"},{"key":"1453_CR19","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.2147\/JPR.S258443","volume":"13","author":"X Li","year":"2020","unstructured":"Li X, Liu Y, Zhao J, Xiang Z, Ren C, Qiao K. The safety and efficacy of Ultrasound-Guided serratus anterior plane block (SAPB) combined with Dexmedetomidine for patients undergoing Video-Assisted thoracic surgery (VATS): a randomized controlled trial. J Pain Res. 2020;13:1785\u201395. https:\/\/doi.org\/10.2147\/JPR.S258443.","journal-title":"J Pain Res"},{"issue":"10","key":"1453_CR20","doi-asserted-by":"publisher","first-page":"995","DOI":"10.5005\/jp-journals-10071-23631","volume":"24","author":"M Gorecha","year":"2020","unstructured":"Gorecha M, Menon A, Woodford E, Yahia S, Marimuthu K. Early serratus plane block for rib fracture management could avoid intensive care unit admission. Indian J Crit Care Med Peer-Rev Off Publ Indian Soc Crit Care Med. 2020;24(10):995. https:\/\/doi.org\/10.5005\/jp-journals-10071-23631.","journal-title":"Indian J Crit Care Med Peer-Rev Off Publ Indian Soc Crit Care Med"},{"issue":"1","key":"1453_CR21","doi-asserted-by":"publisher","DOI":"10.1136\/tsaco-2024-001478","volume":"9","author":"K Mukherjee","year":"2024","unstructured":"Mukherjee K, Kasotakis G, Agarwal S. It takes a village and a multimodal toolbox: pain control after multiple rib fractures. Trauma Surg Acute Care Open. 2024;9(1):e001478. https:\/\/doi.org\/10.1136\/tsaco-2024-001478.","journal-title":"Trauma Surg Acute Care Open"},{"issue":"2","key":"1453_CR22","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1097\/AJP.0000000000001175","volume":"40","author":"Ping Qian","year":"2024","unstructured":"Qian Ping, Zheng Xiaoyu, Wei Huaying, Ji Kemin. Efficacy of serratus anterior plane block versus paravertebral and intercostal blocks for pain control after surgery:: a systematic review and meta-analysis. Clin J Pain. 2024;40(2):124\u201334. https:\/\/doi.org\/10.1097\/AJP.0000000000001175.","journal-title":"Clin J Pain"},{"key":"1453_CR23","doi-asserted-by":"publisher","unstructured":"Chong M, Berbenetz N, Kumar K, Lin C. The serratus plane block for postoperative analgesia in breast and thoracic surgery: a systematic review and meta-analysis. Reg Anesth Pain Med. 2019;rapm\u20132019\u2013100982. https:\/\/doi.org\/10.1136\/rapm-2019-100982. Advance online publication.","DOI":"10.1136\/rapm-2019-100982"},{"issue":"16","key":"1453_CR24","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13164836","volume":"13","author":"M But","year":"2024","unstructured":"But M, Wernicki K, Zieli\u0144ski J, Szczeci\u0144ska W. A comparison of the effectiveness of the serratus anterior plane block and erector spinae plane block to that of the paravertebral block in the surgical treatment of breast cancer-a randomized, prospective, single-blinded study. J Clin Med. 2024;13(16):4836. https:\/\/doi.org\/10.3390\/jcm13164836.","journal-title":"J Clin Med"},{"issue":"9","key":"1453_CR25","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1136\/rapm-2021-102785","volume":"46","author":"RA Gabriel","year":"2021","unstructured":"Gabriel RA, Swisher MW, Sztain JF, Curran BP, Said ET, Abramson WB, Khatibi B, Alexander BS, Finneran JJ, Wallace AM, Armani A, Blair S, Dobke M, Suliman A, Reid C, Donohue MC, Ilfeld BM. Serratus anterior plane versus paravertebral nerve blocks for postoperative analgesia after non-mastectomy breast surgery: a randomized controlled non-inferiority trial. Reg Anesth Pain Med. 2021;46(9):773\u20138. https:\/\/doi.org\/10.1136\/rapm-2021-102785.","journal-title":"Reg Anesth Pain Med"},{"issue":"5","key":"1453_CR26","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1053\/j.jvca.2021.06.029","volume":"36","author":"CH Koo","year":"2022","unstructured":"Koo CH, Lee HT, Na HS, Ryu JH, Shin HJ. Efficacy of erector spinae plane block for analgesia in thoracic surgery: a systematic review and meta-analysis. J Cardiothorac Vasc Anesth. 2022;36(5):1387\u201395. https:\/\/doi.org\/10.1053\/j.jvca.2021.06.029.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"8","key":"1453_CR27","doi-asserted-by":"publisher","first-page":"e0256611","DOI":"10.1371\/journal.pone.0256611","volume":"16","author":"C Xiong","year":"2021","unstructured":"Xiong C, Han C, Zhao D, Peng W, Xu D, Lan Z. Postoperative analgesic effects of paravertebral block versus erector spinae plane block for thoracic and breast surgery: a meta-analysis. PLoS One. 2021;16(8):e0256611. https:\/\/doi.org\/10.1371\/journal.pone.0256611.","journal-title":"PLoS One"},{"issue":"12","key":"1453_CR28","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.23736\/S0375-9393.21.15599-3","volume":"87","author":"G Sepolvere","year":"2021","unstructured":"Sepolvere G, Coppolino F, Tedesco M, Cristiano L. Ultrasound-guided parasternal blocks: techniques, clinical indications and future prospects. Minerva Anestesiol. 2021;87(12):1338\u201346. https:\/\/doi.org\/10.23736\/S0375-9393.21.15599-3.","journal-title":"Minerva Anestesiol"},{"issue":"5","key":"1453_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12052060","volume":"12","author":"G Pascarella","year":"2023","unstructured":"Pascarella G, Costa F, Nonnis G, Strumia A, Sarubbi D, Schiavoni L, et al. Ultrasound guided parasternal block for perioperative analgesia in cardiac surgery: a prospective study. J Clin Med. 2023;12(5):2060. https:\/\/doi.org\/10.3390\/jcm12052060.","journal-title":"J Clin Med"},{"issue":"11","key":"1453_CR30","doi-asserted-by":"publisher","first-page":"4173","DOI":"10.1053\/j.jvca.2022.07.025","volume":"36","author":"L Schiavoni","year":"2022","unstructured":"Schiavoni L, Nenna A, Cardetta F, Pascarella G, Costa F, Chello M, Agr\u00f2 FE, Mattei A. Parasternal intercostal nerve blocks in patients undergoing cardiac surgery: evidence update and technical considerations. J Cardiothorac Vasc Anesth. 2022;36(11):4173\u201382. https:\/\/doi.org\/10.1053\/j.jvca.2022.07.025.","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"1453_CR31","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1007\/s12630-019-01340-9","volume":"66","author":"DF Johnston","year":"2019","unstructured":"Johnston DF, Black ND, O\u2019Halloran R, et al. Cadaveric findings of the effect of rib fractures on spread of serratus plane injections. Can J Anesth\/J Can Anesth. 2019;66:738\u20139. https:\/\/doi.org\/10.1007\/s12630-019-01340-9.","journal-title":"Can J Anesth\/J Can Anesth"},{"key":"1453_CR32","doi-asserted-by":"publisher","first-page":"4717","DOI":"10.2147\/DDDT.S513287","volume":"19","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, Li W, Wei A, Chen S, Wang X. Comparing liposomal bupivacaine and ropivacaine in serratus anterior plane block for thoracoscopic lobectomy: a randomized controlled trial. Drug Des Devel Ther. 2025;19:4717\u201326. https:\/\/doi.org\/10.2147\/DDDT.S513287.","journal-title":"Drug Des Devel Ther"}],"container-title":["Current Pain and Headache Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11916-025-01453-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11916-025-01453-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11916-025-01453-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T12:10:26Z","timestamp":1765800626000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11916-025-01453-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,15]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["1453"],"URL":"https:\/\/doi.org\/10.1007\/s11916-025-01453-5","relation":{},"ISSN":["1531-3433","1534-3081"],"issn-type":[{"value":"1531-3433","type":"print"},{"value":"1534-3081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,15]]},"assertion":[{"value":"13 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"ADK is the editor in chief for CPHRs.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}],"article-number":"5"}}