{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:44:28Z","timestamp":1790675068259,"version":"4.1.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Pain Headache Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11916-026-01495-3","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T10:10:34Z","timestamp":1778148634000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Applications of Celiac Plexus Block in Chronic Pancreatitis or Pancreatic Cancer"],"prefix":"10.1007","volume":"30","author":[{"given":"Xijian","family":"Ke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar","family":"Shekoohi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan D.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"issue":"4","key":"1495_CR1","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.giec.2018.06.004","volume":"28","author":"AH Sachdev","year":"2018","unstructured":"Sachdev AH, Gress FG. Celiac plexus block and neurolysis: A review. Gastrointest Endosc Clin N Am. 2018;28(4):579\u201386. https:\/\/doi.org\/10.1016\/j.giec.2018.06.004.","journal-title":"Gastrointest Endosc Clin N Am"},{"issue":"4","key":"1495_CR2","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1080\/20009666.2021.1929049","volume":"11","author":"AA Asif","year":"2021","unstructured":"Asif AA, Walayat SK, Bechtold ML, Revanur V, Puli SR. EUS-guided celiac plexus neurolysis for pain in pancreatic cancer patients - a meta-analysis and systematic review. J Community Hosp Intern Med Perspect. 2021;11(4):536\u201342. https:\/\/doi.org\/10.1080\/20009666.2021.1929049.","journal-title":"J Community Hosp Intern Med Perspect"},{"issue":"9","key":"1495_CR3","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/jama.291.9.1092","volume":"291","author":"GY Wong","year":"2004","unstructured":"Wong GY, Schroeder DR, Carns PE, Wilson JL, Martin DP, Kinney MO, et al. Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial. JAMA. 2004;291(9):1092\u20139. https:\/\/doi.org\/10.1001\/jama.291.9.1092.","journal-title":"JAMA"},{"issue":"4","key":"1495_CR4","first-page":"E403","volume":"28","author":"D Koyyalagunta","year":"2025","unstructured":"Koyyalagunta D, Mach S, Chung M. Comparison of different spinal level approaches in splanchnic sympathetic neurolysis for intractable upper abdominal cancer pain: A retrospective review. Pain Physician. 2025;28(4):E403\u201310. **Excellent comparison of approaches in splanchnic sympathetic neurolysis.","journal-title":"Pain Physician"},{"issue":"5","key":"1495_CR30","first-page":"379","volume":"24","author":"S Vig","year":"2021","unstructured":"Vig S, Bhan S, Bhatnagar S. Celiac Plexus Block - An old technique with new developments. Pain Physician. 2021;24(5):379\u201398.","journal-title":"Pain Physician"},{"issue":"2","key":"1495_CR31","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1111\/j.1572-0241.2001.03551.x","volume":"96","author":"F Gress","year":"2001","unstructured":"Gress F, Schmitt C, Sherman S, Ciaccia D, Ikenberry S, Lehman G. Endoscopic ultrasound-guided celiac plexus block for managing abdominal pain associated with chronic pancreatitis: a prospective single center experience. Am J Gastroenterol. 2001;96(2):409\u201316. . https:\/\/doi.org\/10.1111\/j.1572-0241.2001.03551.x","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"1495_CR32","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.cgh.2011.09.006","volume":"10","author":"T Stevens","year":"2012","unstructured":"Stevens T, Costanzo A, Lopez R, Kapural L, Parsi MA, Vargo JJ. Adding triamcinolone to endoscopic ultrasound-guided celiac plexus blockade does not reduce pain in patients with chronic pancreatitis. Clin Gastroenterol Hepatol. 2012;10(2):186\u201391. . https:\/\/doi.org\/10.1016\/j.cgh.2011.09.006","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"5","key":"1495_CR33","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1097\/00000658-199305010-00004","volume":"217","author":"KD Lillemoe","year":"1993","unstructured":"Lillemoe KD, Cameron JL, Kaufman HS, Yeo CJ, Pitt HA, Sauter PK. Chemical splanchnicectomy in patients with unresectable pancreatic cancer. A prospective randomized trial. Ann Surg. 1993;217(5):447\u201355. . https:\/\/doi.org\/10.1097\/00000658-199305010-00004","journal-title":"Ann Surg"},{"issue":"Suppl 1","key":"1495_CR34","doi-asserted-by":"publisher","first-page":"S244","DOI":"10.1016\/j.acra.2021.03.005","volume":"28","author":"H Liou","year":"2021","unstructured":"Liou H, Kong MJ, Alzubaidi SJ, Knuttinen MG, Patel IJ, Kriegshauser JS. Single-center review of celiac plexus\/retrocrural splanchnic nerve block for non-cancer related pain. Acad Radiol. 2021;28(Suppl 1):S244\u20139. . https:\/\/doi.org\/10.1016\/j.acra.2021.03.005","journal-title":"Acad Radiol"},{"key":"1495_CR35","doi-asserted-by":"crossref","unstructured":"van Zeggeren L, Boelens Nabbi R, Kallewaard JW, Steegers M, Cohen SP, Kapural L, et al. 16. Pain in chronic pancreatitis. Pain Pract. 2025;25(4):e70030. doi: 10.1111\/papr.70030.","DOI":"10.1111\/papr.70030"},{"issue":"7","key":"1495_CR6","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1111\/papr.13143","volume":"22","author":"M Okita","year":"2022","unstructured":"Okita M, Otani K, Gibo N, Matsui S. Systematic review and meta-analysis of celiac plexus neurolysis for abdominal pain associated with unresectable pancreatic cancer. Pain Pract. 2022;22(7):652\u201361. https:\/\/doi.org\/10.1111\/papr.13143. Interesting systematic review and meta-analysis of celiac plexus neurolysis for abdominal pain associated with pancreatic cancer.","journal-title":"Pain Pract"},{"issue":"1","key":"1495_CR36","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1159\/000508293","volume":"28","author":"P Moutinho-Ribeiro","year":"2020","unstructured":"Moutinho-Ribeiro P, Costa-Moreira P, Caldeira A, Leite S, Marques S, Moreira T, et al. Endoscopic ultrasound-guided celiac plexus interventions. GE Portuguese J Gastroenterol. 2020;28(1):32\u20138. . https:\/\/doi.org\/10.1159\/000508293","journal-title":"GE Portuguese J Gastroenterol"},{"issue":"10","key":"1495_CR7","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1007\/s11894-023-00898-1","volume":"25","author":"A Maydeo","year":"2023","unstructured":"Maydeo A, Kamat N, Dalal A, Patil G. Advances in the management of pain in chronic pancreatitis. Curr Gastroenterol Rep. 2023;25(10):260\u20136. https:\/\/doi.org\/10.1007\/s11894-023-00898-1.","journal-title":"Curr Gastroenterol Rep"},{"issue":"1","key":"1495_CR8","doi-asserted-by":"publisher","first-page":"E56","DOI":"10.1055\/s-0034-1377919","volume":"3","author":"MS Sey","year":"2015","unstructured":"Sey MS, Schmaltz L, Al-Haddad MA, DeWitt JM, Calley CS, Juan M, et al. Effectiveness and safety of serial endoscopic ultrasound-guided celiac plexus block for chronic pancreatitis. Endosc Int Open. 2015;3(1):E56\u20139. https:\/\/doi.org\/10.1055\/s-0034-1377919.","journal-title":"Endosc Int Open"},{"issue":"2","key":"1495_CR12","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1097\/MCG.0b013e3181bb854d","volume":"44","author":"M Kaufman","year":"2010","unstructured":"Kaufman M, Singh G, Das S, Concha-Parra R, Erber J, Micames C, et al. Efficacy of endoscopic ultrasound-guided celiac plexus block and celiac plexus neurolysis for managing abdominal pain associated with chronic pancreatitis and pancreatic cancer. J Clin Gastroenterol. 2010;44(2):127\u201334. https:\/\/doi.org\/10.1097\/MCG.0b013e3181bb854d.","journal-title":"J Clin Gastroenterol"},{"issue":"6","key":"1495_CR13","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1016\/j.pan.2025.08.006","volume":"25","author":"JD Machicado","year":"2025","unstructured":"Machicado JD, Tanner S, Adoor D, Chalhoub JM, Plann-Curley B, Lee UJ, et al. Endoscopic ultrasound-guided celiac plexus block for painful chronic pancreatitis: A systematic review and meta-analysis. Pancreatology. 2025;25(6):860\u20137. https:\/\/doi.org\/10.1016\/j.pan.2025.08.006.","journal-title":"Pancreatology"},{"issue":"9","key":"1495_CR14","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1111\/j.1365-2036.2009.03963.x","volume":"29","author":"D Santosh","year":"2009","unstructured":"Santosh D, Lakhtakia S, Gupta R, Reddy DN, Rao GV, Tandan M, et al. Clinical trial: a randomized trial comparing fluoroscopy guided percutaneous technique vs. endoscopic ultrasound guided technique of coeliac plexus block for treatment of pain in chronic pancreatitis. Aliment Pharmacol Ther. 2009;29(9):979\u201384. https:\/\/doi.org\/10.1111\/j.1365-2036.2009.03963.x.","journal-title":"Aliment Pharmacol Ther"},{"key":"1495_CR15","doi-asserted-by":"publisher","unstructured":"Gress F, Schmitt C, Sherman S, Ikenberry S, Lehman G. A prospective randomized comparison of endoscopic ultrasound- and computed tomography-guided celiac plexus block for managing chronic pancreatitis pain. Am J Gastroenterol. 1999;94(4):900\u20135. https:\/\/doi.org\/10.1111\/j.1572-0241.1999 01042.x. **Interesting randomized trial of ultrasound and computed tomography-guided celiac plexus block for chronic pancreatitis.","DOI":"10.1111\/j.1572-0241.1999"},{"issue":"2","key":"1495_CR18","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/0304-3959(93)90130-H","volume":"52","author":"S Mercadante","year":"1993","unstructured":"Mercadante S. Celiac plexus block versus analgesics in pancreatic cancer pain. Pain. 1993;52(2):187\u201392. https:\/\/doi.org\/10.1016\/0304-3959(93)90130-H.","journal-title":"Pain"},{"issue":"3","key":"1495_CR19","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/0304-3959(95)00189-1","volume":"64","author":"M Kawamata","year":"1996","unstructured":"Kawamata M, Ishitani K, Ishikawa K, Sasaki H, Ota K, Omote K, et al. Comparison between celiac plexus block and morphine treatment on quality of life in patients with pancreatic cancer pain. Pain. 1996;64(3):597\u2013602. https:\/\/doi.org\/10.1016\/0304-3959(95)00189-1.","journal-title":"Pain"},{"issue":"2","key":"1495_CR20","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1046\/j.1365-2168.1998.00563.x","volume":"85","author":"E Polati","year":"1998","unstructured":"Polati E, Finco G, Gottin L, Bassi C, Pederzoli P, Ischia S. Prospective randomized double-blind trial of neurolytic coeliac plexus block in patients with pancreatic cancer. Br J Surg. 1998;85(2):199\u2013201. https:\/\/doi.org\/10.1046\/j.1365-2168.1998.00563.x.","journal-title":"Br J Surg"},{"issue":"3","key":"1495_CR21","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1007\/s10620-007-9905-2","volume":"53","author":"CL Zhang","year":"2008","unstructured":"Zhang CL, Zhang TJ, Guo YN, Yang LQ, He MW, Shi JZ, et al. Effect of neurolytic celiac plexus block guided by computerized tomography on pancreatic cancer pain. Dig Dis Sci. 2008;53(3):856\u201360. https:\/\/doi.org\/10.1007\/s10620-007-9905-2.","journal-title":"Dig Dis Sci"},{"issue":"6","key":"1495_CR22","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1159\/000199441","volume":"9","author":"CD Johnson","year":"2009","unstructured":"Johnson CD, Berry DP, Harris S, Pickering RM, Davis C, George S, et al. An open randomized comparison of clinical effectiveness of protocol-driven opioid analgesia, celiac plexus block or thoracoscopic splanchnicectomy for pain management in patients with pancreatic and other abdominal malignancies. Pancreatology. 2009;9(6):755\u201363. https:\/\/doi.org\/10.1159\/000199441.","journal-title":"Pancreatology"},{"issue":"26","key":"1495_CR23","doi-asserted-by":"publisher","first-page":"3541","DOI":"10.1200\/JCO.2010.32.2750","volume":"29","author":"JM Wyse","year":"2011","unstructured":"Wyse JM, Carone M, Paquin SC, Usatii M, Sahai AV. Randomized, double-blind, controlled trial of early endoscopic ultrasound-guided celiac plexus neurolysis to prevent pain progression in patients with newly diagnosed, painful, inoperable pancreatic cancer. J Clin Oncol. 2011;29(26):3541\u20136. https:\/\/doi.org\/10.1200\/JCO.2010.32.2750.","journal-title":"J Clin Oncol"},{"issue":"3","key":"1495_CR24","doi-asserted-by":"publisher","first-page":"2297","DOI":"10.1007\/s13277-013-1304-z","volume":"35","author":"L Gao","year":"2014","unstructured":"Gao L, Yang YJ, Xu HY, Zhou J, Hong H, Wang YL, et al. A randomized clinical trial of nerve block to manage end-stage pancreatic cancerous pain. Tumour Biol. 2014;35(3):2297\u2013301. https:\/\/doi.org\/10.1007\/s13277-013-1304-z.","journal-title":"Tumour Biol"},{"issue":"1","key":"1495_CR25","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.gie.2020.01.011","volume":"92","author":"Y Kanno","year":"2020","unstructured":"Kanno Y, Koshita S, Masu K, Ogawa T, Kusunose H, Murabayashi T, et al. Efficacy of EUS-guided celiac plexus neurolysis compared with medication alone for unresectable pancreatic cancer in the oxycodone\/fentanyl era: a prospective randomized control study. Gastrointest Endosc. 2020;92(1):120\u201330. https:\/\/doi.org\/10.1016\/j.gie.2020.01.011.","journal-title":"Gastrointest Endosc"},{"issue":"8","key":"1495_CR27","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1111\/j.1445-2197.2005.03486.x","volume":"75","author":"G Garcea","year":"2005","unstructured":"Garcea G, Thomasset S, Berry DP, Tordoff S. Percutaneous splanchnic nerve radiofrequency ablation for chronic abdominal pain. ANZ J Surg. 2005;75(8):640\u20134. https:\/\/doi.org\/10.1111\/j.1445-2197.2005.03486.x.","journal-title":"ANZ J Surg"},{"issue":"8","key":"1495_CR28","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1111\/papr.12030","volume":"13","author":"BP Verhaegh","year":"2013","unstructured":"Verhaegh BP, van Kleef M, Geurts JW, Puylaert M, van Zundert J, Kessels AG, et al. Percutaneous radiofrequency ablation of the splanchnic nerves in patients with chronic pancreatitis: results of single and repeated procedures in 11 patients. Pain Pract. 2013;13(8):621\u20136. https:\/\/doi.org\/10.1111\/papr.12030.","journal-title":"Pain Pract"},{"issue":"1","key":"1495_CR29","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1111\/ner.13051","volume":"23","author":"CB Ratnayake","year":"2020","unstructured":"Ratnayake CB, Bunn A, Pandanaboyana S, Windsor JA. Spinal cord stimulation for management of pain in chronic pancreatitis: A systematic review of efficacy and complications. Neuromodulation. 2020;23(1):19\u201325. https:\/\/doi.org\/10.1111\/ner.13051.","journal-title":"Neuromodulation"}],"container-title":["Current Pain and Headache Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11916-026-01495-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11916-026-01495-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11916-026-01495-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T10:10:37Z","timestamp":1778148637000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11916-026-01495-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,7]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["1495"],"URL":"https:\/\/doi.org\/10.1007\/s11916-026-01495-3","relation":{},"ISSN":["1531-3433","1534-3081"],"issn-type":[{"value":"1531-3433","type":"print"},{"value":"1534-3081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,7]]},"assertion":[{"value":"9 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This article is based on previous studies and contains no new studies with human participants or animals performed by any authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Guidelines"}},{"value":"ADK is the editor-in-chief for CPHRs. CLR is the section editor for CPHRs.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"63"}}