{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T08:42:00Z","timestamp":1785660120453,"version":"3.56.0"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T00:00:00Z","timestamp":1470182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T00:00:00Z","timestamp":1470182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Psychiatry Rep"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1007\/s11920-016-0718-x","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T07:58:17Z","timestamp":1470211097000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Alcohol and Opioid Use Disorder in Older Adults: Neglected and Treatable Illnesses"],"prefix":"10.1007","volume":"18","author":[{"given":"Christoffel","family":"Le Roux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Drexler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,8,3]]},"reference":[{"issue":"10","key":"718_CR1","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1001\/jama.291.10.1238","volume":"291","author":"AH Mokdad","year":"2004","unstructured":"Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the United States, 2000. JAMA. 2004;291(10):1238\u201345.","journal-title":"JAMA"},{"issue":"5","key":"718_CR2","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.mayocp.2015.03.012","volume":"90","author":"TJ Bommersbach","year":"2015","unstructured":"Bommersbach TJ, Lapid MI, Rummans TA, Morse RM. Geriatric alcohol use disorder: a review for primary care physicians. Mayo Clin Proc. 2015;90(5):659\u201366. Recent article, alcohol specific, outlines risk factors and complications of alcohol use disorder in the geriatric population.","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"718_CR3","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1177\/0898264310386224","volume":"23","author":"LT Wu","year":"2011","unstructured":"Wu LT, Blazer DG. Illicit and nonmedical drug use among older adults: a review. J Aging Health. 2011;23(3):481\u2013504. Recent review article, discuss epidemiology and summarizes peer-reviewed studies outlining the documented prevalence of SUD in late-life.","journal-title":"J Aging Health"},{"key":"718_CR4","doi-asserted-by":"crossref","unstructured":"Oslin DW, Mavandadi S. Chapter 9: alcohol and drug problems. Clinical Manual of Geriatric Psychiatry 2014. Only textbook chapter in American Psychiatric Publishing that discuss combined problem of SUD in older adults, good review explaining standard drink concept and screening instruments.","DOI":"10.1176\/appi.books.9781615370016.mt09"},{"key":"718_CR5","unstructured":"Colby SL, Ortman J. The baby boom cohort in the United States: 2012 to 2060. 2015."},{"issue":"3","key":"718_CR6","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.cger.2014.04.008","volume":"30","author":"A Kuerbis","year":"2014","unstructured":"Kuerbis A, Sacco P, Blazer DG, Moore AA. Substance abuse among older adults. Clin Geriatr Med. 2014;30(3):629\u201354. Recent thorough review, outlining risk factors for SUD in older adults, reasons for DSM criteria not sufficient alone in diagnosis of SUD and alternative indicators of SUD.","journal-title":"Clin Geriatr Med"},{"issue":"15","key":"718_CR7","first-page":"1","volume":"50","author":"AM Minino","year":"2002","unstructured":"Minino AM, Arias E, Kochanek KD, Murphy SL, Smith BL. Deaths: final data for 2000. Natl Vital Stat Rep. 2002;50(15):1\u2013119.","journal-title":"Natl Vital Stat Rep"},{"key":"718_CR8","unstructured":"Substance Abuse and Mental Health Services Administration. Results from the 2013 National Survey on Drug Use and Health: summary of national findings, NSDUH Series H-48, HHS Publication No. (SMA) 14-4863. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2014."},{"key":"718_CR9","unstructured":"Pradip K. Muhuri JCG, M. Christine Davies. Associations of nonmedical pain reliever use and initiation of heroin use in the United States. 2013."},{"key":"718_CR10","unstructured":"Volkow ND. America\u2019s addiction to opioids: heroin and prescription drug abuse. 2014."},{"key":"718_CR11","doi-asserted-by":"crossref","unstructured":"Beauchamp, al. e. Moving beyond misuse and diversion: the urgent need to consider the role of iatrogenic addiction in the current opioid epidemic. Am J Publ Health. 2014;104(11):2023-9.","DOI":"10.2105\/AJPH.2014.302147"},{"key":"718_CR12","unstructured":"Paice JA, al. e. Safe use of opioids in hospitals. 2012 Contract No.: Issue 49, August 8, 2012."},{"key":"718_CR13","doi-asserted-by":"crossref","unstructured":"Deborah Dowell MTMH, PhD; Roger Chou, MD. CDC guideline for prescribing opioids for chronic pain\u2014United States, 2016. 2016.","DOI":"10.1001\/jama.2016.1464"},{"issue":"13","key":"718_CR14","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1056\/NEJMra1507771","volume":"374","author":"ND Volkow","year":"2016","unstructured":"Volkow ND, McLellan AT. Opioid abuse in chronic pain\u2014misconceptions and mitigation strategies. N Engl J Med. 2016;374(13):1253\u201363. Recent article addressing the current paradigm shift about the risks and ineffectiveness of using opioids for non-specific chronic pain.","journal-title":"N Engl J Med"},{"issue":"7","key":"718_CR15","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1046\/j.1360-0443.1999.9479612.x","volume":"94","author":"JM White","year":"1999","unstructured":"White JM, Irvine RJ. Mechanisms of fatal opioid overdose. Addiction. 1999;94(7):961\u201372.","journal-title":"Addiction"},{"key":"718_CR16","unstructured":"Taffet GE. Geriatrics Review Syllabus: a core curriculum in geriatric medicine 5th ed. 1999."},{"issue":"4","key":"718_CR17","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1067\/mlc.2001.118090","volume":"138","author":"HJ Armbrecht","year":"2001","unstructured":"Armbrecht HJ. The biology of aging. J Lab Clin Med. 2001;138(4):220\u20135.","journal-title":"J Lab Clin Med"},{"issue":"11","key":"718_CR18","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1016\/j.jpain.2010.07.002","volume":"11","author":"CB Johannes","year":"2010","unstructured":"Johannes CB, Le TK, Zhou X, Johnston JA, Dworkin RH. The prevalence of chronic pain in United States adults: results of an Internet-based survey. J Pain :Off J Am Pain Soc. 2010;11(11):1230\u20139.","journal-title":"J Pain :Off J Am Pain Soc"},{"issue":"1","key":"718_CR19","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1007\/s13142-012-0110-2","volume":"2","author":"J Steglitz","year":"2012","unstructured":"Steglitz J, Buscemi J, Ferguson MJ. The future of pain research, education, and treatment: a summary of the IOM report \u201cRelieving pain in America: a blueprint for transforming prevention, care, education, and research\u201d. Transl Behav Med. 2012;2(1):6\u20138.","journal-title":"Transl Behav Med"},{"issue":"13-14","key":"718_CR20","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.3109\/10826089509071062","volume":"30","author":"CL Joseph","year":"1995","unstructured":"Joseph CL. Alcohol and drug misuse in the nursing home. Int J Addict. 1995;30(13-14):1953\u201384.","journal-title":"Int J Addict"},{"issue":"3","key":"718_CR21","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1093\/hsw\/27.3.193","volume":"27","author":"WC Klein","year":"2002","unstructured":"Klein WC. One last pleasure? Alcohol use among elderly people in nursing homes. Health Soc Work. 2002;27(3):193\u2013203.","journal-title":"Health Soc Work"},{"key":"718_CR22","unstructured":"Alcoholics Anonymous: the story of how many thousands of men and women have recovered from alcoholism. 4th edition. ed. New York City: New York City: Alcoholics Anonymous World Services; 2001."},{"issue":"Suppl 6","key":"718_CR23","doi-asserted-by":"publisher","first-page":"s46","DOI":"10.7861\/clinmedicine.13-6-s46","volume":"13","author":"I Crome","year":"2013","unstructured":"Crome I. Substance misuse in the older person: setting higher standards. Clin Med (Lond). 2013;13 Suppl 6:s46\u20139.","journal-title":"Clin Med (Lond)"},{"key":"718_CR24","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association, American Psychiatric Association. DSM-5 Task Force. Diagnostic and Statistical Manual of Mental Disorders: DSM-5. 5th ed. Washington, D.C.: American Psychiatric Association; 2013. xliv, 947 p. p.","DOI":"10.1176\/appi.books.9780890425596"},{"issue":"8","key":"718_CR25","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1097\/JGP.0b013e3182006a96","volume":"19","author":"DG Blazer","year":"2011","unstructured":"Blazer DG, Wu LT. The epidemiology of alcohol use disorders and subthreshold dependence in a middle-aged and elderly community sample. Am J Geriatr Psychiatry. 2011;19(8):685\u201394.","journal-title":"Am J Geriatr Psychiatry"},{"issue":"6","key":"718_CR26","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.exger.2012.03.019","volume":"47","author":"F Caputo","year":"2012","unstructured":"Caputo F, Vignoli T, Leggio L, Addolorato G, Zoli G, Bernardi M. Alcohol use disorders in the elderly: a brief overview from epidemiology to treatment options. Exp Gerontol. 2012;47(6):411\u20136.","journal-title":"Exp Gerontol"},{"key":"718_CR27","volume-title":"Summary health statistics for U.S. adults: national health interview survey","author":"National Center for Health Statistics","year":"2012","unstructured":"National Center for Health Statistics. Summary health statistics for U.S. adults: national health interview survey. Hyattsville: National Center for Health Statistics, 2014; 2012."},{"key":"718_CR28","unstructured":"U.S. Department of Agriculture. Dietary guidelines for Americans 2015 [Available from: http:\/\/www.cnpp.usda.gov\/sites\/default\/files\/dietary_guidelines_for_americans\/ExecSumm.pdf."},{"key":"718_CR29","unstructured":"National Institute on Alcohol Abuse and Alcoholism (NIAAA). Drinking levels defined 2016 [Available from: https:\/\/www.niaaa.nih.gov\/alcohol-health\/overview-alcohol-consumption\/moderate-binge-drinking."},{"issue":"9","key":"718_CR30","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1002\/gps.2498","volume":"26","author":"M Aalto","year":"2011","unstructured":"Aalto M, Alho H, Halme JT, Seppa K. The Alcohol Use Disorders Identification Test (AUDIT) and its derivatives in screening for heavy drinking among the elderly. Int J Geriatr Psychiatry. 2011;26(9):881\u20135.","journal-title":"Int J Geriatr Psychiatry"},{"issue":"9","key":"718_CR31","doi-asserted-by":"publisher","first-page":"645","DOI":"10.7326\/0003-4819-157-9-201211060-00544","volume":"157","author":"DE Jonas","year":"2012","unstructured":"Jonas DE, Garbutt JC, Amick HR, Brown JM, Brownley KA, Council CL, et al. Behavioral counseling after screening for alcohol misuse in primary care: a systematic review and meta-analysis for the U.S. Preventive Services Task Force. Ann Intern Med. 2012;157(9):645\u201354.","journal-title":"Ann Intern Med"},{"issue":"7","key":"718_CR32","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1111\/j.1530-0277.2007.00403.x","volume":"31","author":"KA Bradley","year":"2007","unstructured":"Bradley KA, DeBenedetti AF, Volk RJ, Williams EC, Frank D, Kivlahan DR. AUDIT-C as a brief screen for alcohol misuse in primary care. Alcohol Clin Exp Res. 2007;31(7):1208\u201317.","journal-title":"Alcohol Clin Exp Res"},{"issue":"7","key":"718_CR33","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1001\/archinte.163.7.821","volume":"163","author":"KA Bradley","year":"2003","unstructured":"Bradley KA, Bush KR, Epler AJ, Dobie DJ, Davis TM, Sporleder JL, et al. Two brief alcohol-screening tests from the Alcohol Use Disorders Identification Test (AUDIT): validation in a female Veterans Affairs patient population. Arch Intern Med. 2003;163(7):821\u20139.","journal-title":"Arch Intern Med"},{"issue":"16","key":"718_CR34","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1001\/archinte.158.16.1789","volume":"158","author":"K Bush","year":"1998","unstructured":"Bush K, Kivlahan DR, McDonell MB, Fihn SD, Bradley KA. The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test. Arch Intern Med. 1998;158(16):1789\u201395.","journal-title":"Arch Intern Med"},{"issue":"6","key":"718_CR35","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1007\/s11606-008-0594-0","volume":"23","author":"D Frank","year":"2008","unstructured":"Frank D, DeBenedetti AF, Volk RJ, Williams EC, Kivlahan DR, Bradley KA. Effectiveness of the AUDIT-C as a screening test for alcohol misuse in three race\/ethnic groups. J Gen Intern Med. 2008;23(6):781\u20137.","journal-title":"J Gen Intern Med"},{"key":"718_CR36","unstructured":"National Institute on Alcohol Abuse and Alcoholism (NIAAA). Brief interventions. 2005."},{"issue":"5","key":"718_CR37","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1093\/alcalc\/34.5.760","volume":"34","author":"G Mundle","year":"1999","unstructured":"Mundle G, Ackermann K, Munkes J, Steinle D, Mann K. Influence of age, alcohol consumption and abstinence on the sensitivity of carbohydrate-deficient transferrin, gamma-glutamyltransferase and mean corpuscular volume. Alcohol Alcohol. 1999;34(5):760\u20136.","journal-title":"Alcohol Alcohol"},{"issue":"6","key":"718_CR38","first-page":"1443","volume":"69","author":"M Bayard","year":"2004","unstructured":"Bayard M, McIntyre J, Hill KR, Woodside Jr J. Alcohol withdrawal syndrome. Am Fam Physician. 2004;69(6):1443\u201350.","journal-title":"Am Fam Physician"},{"issue":"12","key":"718_CR39","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1111\/j.1468-1331.2010.03153.x","volume":"17","author":"R Galvin","year":"2010","unstructured":"Galvin R, Brathen G, Ivashynka A, Hillbom M, Tanasescu R, Leone MA, et al. EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy. Eur J Neurol. 2010;17(12):1408\u201318.","journal-title":"Eur J Neurol"},{"issue":"11","key":"718_CR40","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1111\/j.1360-0443.1989.tb00737.x","volume":"84","author":"JT Sullivan","year":"1989","unstructured":"Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM. Assessment of alcohol withdrawal: the revised Clinical Institute Withdrawal Assessment for alcohol scale (CIWA-Ar). Br J Addict. 1989;84(11):1353\u20137.","journal-title":"Br J Addict"},{"issue":"8","key":"718_CR41","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1111\/jgs.12932","volume":"62","author":"A Taheri","year":"2014","unstructured":"Taheri A, Dahri K, Chan P, Shaw M, Aulakh A, Tashakkor A. Evaluation of a symptom-triggered protocol approach to the management of alcohol withdrawal syndrome in older adults. J Am Geriatr Soc. 2014;62(8):1551\u20135.","journal-title":"J Am Geriatr Soc"},{"issue":"2","key":"718_CR42","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1001\/jama.1997.03550020076042","volume":"278","author":"MF Mayo-Smith","year":"1997","unstructured":"Mayo-Smith MF. Pharmacological management of alcohol withdrawal. A meta-analysis and evidence-based practice guideline. American Society of Addiction Medicine Working Group on Pharmacological Management of Alcohol Withdrawal. JAMA. 1997;278(2):144\u201351.","journal-title":"JAMA"},{"key":"718_CR43","unstructured":"Mee-Lee D, American Society of Addiction Medicine. The ASAM criteria: treatment for addictive, substance-related, and co-occurring conditions. Third edition. ed. Chevy Chase, Maryland: American Society of Addiction Medicine; 2013. xv, 460 pages p."},{"key":"718_CR44","unstructured":"Drexler K, Perry C, Kivlahan D, et al. VA\/DoD clinical practice guideline for the management of substance use disorders. 2015."},{"key":"718_CR45","volume-title":"Pharmacotherapy for adults with alcohol-use disorders in outpatient settings","author":"DE Jonas","year":"2014","unstructured":"Jonas DE, Amick HR, Feltner C, Bobashev G, Thomas K, Wines R, et al. Pharmacotherapy for adults with alcohol-use disorders in outpatient settings. Rockville (MD): AHRQ Comparative Effectiveness Reviews; 2014."},{"issue":"2","key":"718_CR46","doi-asserted-by":"publisher","first-page":"190","DOI":"10.4088\/JCP.v69n0204","volume":"69","author":"DA Ciraulo","year":"2008","unstructured":"Ciraulo DA, Dong Q, Silverman BL, Gastfriend DR, Pettinati HM. Early treatment response in alcohol dependence with extended-release naltrexone. J Clin Psychiatry. 2008;69(2):190\u20135.","journal-title":"J Clin Psychiatry"},{"key":"718_CR47","doi-asserted-by":"crossref","unstructured":"Rosner S, Hackl-Herrwerth A, Leucht S, Lehert P, Vecchi S, Soyka M. Acamprosate for alcohol dependence. The Cochrane database of systematic reviews. 2010(9):Cd004332","DOI":"10.1002\/14651858.CD004332.pub2"},{"key":"718_CR48","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.ypmed.2015.04.003","volume":"80","author":"WM Compton","year":"2015","unstructured":"Compton WM, Boyle M, Wargo E. Prescription opioid abuse: problems and responses. Prev Med. 2015;80:5\u20139.","journal-title":"Prev Med"},{"issue":"4","key":"718_CR49","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1185\/03007995.2015.1016607","volume":"31","author":"A Shei","year":"2015","unstructured":"Shei A, Rice JB, Kirson NY, Bodnar K, Birnbaum HG, Holly P, et al. Sources of prescription opioids among diagnosed opioid abusers. Curr Med Res Opin. 2015;31(4):779\u201384.","journal-title":"Curr Med Res Opin"},{"key":"718_CR50","unstructured":"Department of Veterans Affairs (VA). Pain Management Opioid Safety VA Educational Guide (2014) 2014 Contract No.: May 30, 2016."},{"issue":"5","key":"718_CR51","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1111\/pme.12699","volume":"16","author":"A Westanmo","year":"2015","unstructured":"Westanmo A, Marshall P, Jones E, Burns K, Krebs EE. Opioid dose reduction in a VA health care system\u2014implementation of a primary care population-level initiative. Pain Med. 2015;16(5):1019\u201326.","journal-title":"Pain Med"},{"key":"718_CR52","doi-asserted-by":"crossref","unstructured":"Taylor MH, Grossberg GT. The growing problem of illicit substance abuse in the elderly: a review. Prim Care Companion CNS Disord. 2012;14(4).","DOI":"10.4088\/PCC.11r01320"},{"key":"718_CR53","unstructured":"The American Society of Addiction Medicine (ASAM). National practice guideline for the use of medications in the treatment of addiction involving opioid use. 2015."},{"key":"718_CR54","volume":"4","author":"S Minozzi","year":"2011","unstructured":"Minozzi S, Amato L, Vecchi S, Davoli M, Kirchmayer U, Verster A. Oral naltrexone maintenance treatment for opioid dependence. Cochrane Database Syst Rev. 2011;4, CD001333.","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"718_CR55","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1016\/j.drugalcdep.2013.04.021","volume":"132","author":"E Krupitsky","year":"2013","unstructured":"Krupitsky E, Zvartau E, Blokhina E, Verbitskaya E, Tsoy M, Wahlgren V, et al. Naltrexone with or without guanfacine for preventing relapse to opiate addiction in St.-Petersburg, Russia. Drug Alcohol Depend. 2013;132(3):674\u201380.","journal-title":"Drug Alcohol Depend"},{"issue":"5","key":"718_CR56","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1111\/j.1521-0391.2010.00070.x","volume":"19","author":"DM Coviello","year":"2010","unstructured":"Coviello DM, Cornish JW, Lynch KG, Alterman AI, O\u2019Brien CP. A randomized trial of oral naltrexone for treating opioid-dependent offenders. Am J Addict. 2010;19(5):422\u201332.","journal-title":"Am J Addict"},{"issue":"9631","key":"718_CR57","doi-asserted-by":"publisher","first-page":"2192","DOI":"10.1016\/S0140-6736(08)60954-X","volume":"371","author":"RS Schottenfeld","year":"2008","unstructured":"Schottenfeld RS, Chawarski MC, Mazlan M. Maintenance treatment with buprenorphine and naltrexone for heroin dependence in Malaysia: a randomised, double-blind, placebo-controlled trial. Lancet. 2008;371(9631):2192\u2013200.","journal-title":"Lancet"},{"issue":"9776","key":"718_CR58","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1016\/S0140-6736(11)60358-9","volume":"377","author":"E Krupitsky","year":"2011","unstructured":"Krupitsky E, Nunes EV, Ling W, Illeperuma A, Gastfriend DR, Silverman BL. Injectable extended-release naltrexone for opioid dependence: a double-blind, placebo-controlled, multicentre randomised trial. Lancet. 2011;377(9776):1506\u201313.","journal-title":"Lancet"},{"issue":"13","key":"718_CR59","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1056\/NEJMoa1505409","volume":"374","author":"JD Lee","year":"2016","unstructured":"Lee JD, Friedmann PD, Kinlock TW, Nunes EV, Boney TY, Hoskinson Jr RA, et al. Extended-release naltrexone to prevent opioid relapse in criminal justice offenders. N Engl J Med. 2016;374(13):1232\u201342.","journal-title":"N Engl J Med"},{"key":"718_CR60","volume":"2","author":"RP Mattick","year":"2014","unstructured":"Mattick RP, Breen C, Kimber J, Davoli M. Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database Syst Rev. 2014;2, CD002207.","journal-title":"Cochrane Database Syst Rev"},{"key":"718_CR61","volume":"3","author":"RP Mattick","year":"2009","unstructured":"Mattick RP, Breen C, Kimber J, Davoli M. Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence. Cochrane Database Syst Rev. 2009;3, CD002209.","journal-title":"Cochrane Database Syst Rev"},{"issue":"18","key":"718_CR62","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1056\/NEJM200011023431802","volume":"343","author":"RE Johnson","year":"2000","unstructured":"Johnson RE, Chutuape MA, Strain EC, Walsh SL, Stitzer ML, Bigelow GE. A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence. N Engl J Med. 2000;343(18):1290\u20137.","journal-title":"N Engl J Med"},{"key":"718_CR63","unstructured":"Frederic C. Blow PD, James Campbell, M.D., M.S. et al. Substance abuse among older adults Treatment Improvement Protocol (TIP) Series 26. 1998."},{"key":"718_CR64","unstructured":"Herbert D. Kleber MD, Chair, Roger D. Weiss MD, Vice-Chair, al. e. American Psychiatric Association Practice Guideline for the Treatment of Patients with Substance Use Disorders Second Edition. 2006."},{"key":"718_CR65","doi-asserted-by":"crossref","unstructured":"Hilary Smith Connery MD, Ph.D., Herbert D. Kleber MD. Guideline Watch (April 2007): practice guideline for the treatment of patients with substance use disorders, 2nd Edition. 2007.","DOI":"10.1176\/foc.5.2.foc163"}],"container-title":["Current Psychiatry Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11920-016-0718-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11920-016-0718-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11920-016-0718-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11920-016-0718-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:57:14Z","timestamp":1744174634000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11920-016-0718-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,3]]},"references-count":65,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["718"],"URL":"https:\/\/doi.org\/10.1007\/s11920-016-0718-x","relation":{},"ISSN":["1523-3812","1535-1645"],"issn-type":[{"value":"1523-3812","type":"print"},{"value":"1535-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,3]]},"assertion":[{"value":"3 August 2016","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"Christoffel Le Roux and Karen Drexler declare that they have no conflict of interest.Yilang Tang has received a grant from Janssen Pharmaceuticals, Inc.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article does not contain any studies with human or animal subjects performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}],"article-number":"87"}}