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Methamphetamine-induced psychosis is associated with frontal lobe reductions and smaller hippocampal and amygdalar volumes. Cannabis use is linked to alterations in the cingulate cortex and cerebellar networks, particularly when use begins early in life. While many neuroimaging patterns overlap with schizophrenia substance-specific variations exist. For instance, methamphetamine users show more pronounced amygdalar reduction than those with primary psychosis. Generally, structural deficits are more severe and widespread in schizophrenia than in purely substance-induced cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Substance-induced psychoses exhibit neuroanatomical signatures largely similar to primary psychoses, though distinct regional variations suggest partially divergent mechanisms. Future longitudinal and multimodal research is essential to identify definitive biomarkers for clinical differentiation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11920-026-01678-0","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:34:38Z","timestamp":1777534478000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structural Neuroimaging in Substance-Induced Psychosis"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2772-4124","authenticated-orcid":false,"given":"Murad","family":"Atmaca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-5622","authenticated-orcid":false,"given":"Muhammed Fatih","family":"Tabara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"1678_CR1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. 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