{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T10:44:00Z","timestamp":1786358640822,"version":"build-2736575974"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Rheumatol Rep"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1007\/s11926-006-0049-8","type":"journal-article","created":{"date-parts":[[2007,6,2]],"date-time":"2007-06-02T16:00:40Z","timestamp":1180800040000},"page":"100-108","source":"Crossref","is-referenced-by-count":47,"title":["The prevalence and clinical significance of antiphospholipid antibodies in rheumatoid arthritis"],"prefix":"10.1007","volume":"8","author":[{"given":"Ewa","family":"Olech","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan T.","family":"Merrill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"49_CR1","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1056\/NEJMra002974","volume":"346","author":"JS Levine","year":"2002","unstructured":"Levine JS, Branch DW, Rauch J: The antiphospholipid syndrome. N Engl J Med 2002, 346:752\u2013763. Extensive review of aPL antibodies and APS including the classification criteria and therapy.","journal-title":"N Engl J Med"},{"key":"49_CR2","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0889-857X(05)70218-0","volume":"27","author":"J T Merrill","year":"2001","unstructured":"Merrill J T: Which antiphospholipid antibody tests are most useful? Rheum Dis Clin North Am 2001, 27:525\u2013549.","journal-title":"Rheum Dis Clin North Am"},{"key":"49_CR3","first-page":"22","volume":"1","author":"PG Groot de","year":"1995","unstructured":"de Groot PG, Derksen RHWM: Specificity and clinical relevance of lupus anticoagulant. Vessels 1995, 1:22\u201326.","journal-title":"Vessels"},{"key":"49_CR4","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1056\/NEJMra002974","volume":"346","author":"JS Levine","year":"2002","unstructured":"Levine JS, Branch DW, Rauch J: The antiphospholipid syndrome. N Engl J Med 2002, 346:752\u2013763.","journal-title":"N Engl J Med"},{"key":"49_CR5","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1006\/jaut.2000.0413","volume":"15","author":"M Galli","year":"2000","unstructured":"Galli M: Should we include anti-prothrombin antibodies in the screening for the antiphospholipid syndrome? J Autoimmun 2000, 15:101\u2013105.","journal-title":"J Autoimmun"},{"issue":"Suppl 2","key":"49_CR6","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1177\/096120339800700208","volume":"7","author":"PG Groot de","year":"1998","unstructured":"de Groot PG, Horbach DA, Simmelink MJ, et al.:Anti-prothrombin antibodies and their relation with thrombosis and lupus anticoagulant. Lupus 1998, 7(Suppl 2):S32-S36.","journal-title":"Lupus"},{"key":"49_CR7","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1309\/YVQ6PX76XMYM3J29","volume":"121","author":"LR Lopez","year":"2004","unstructured":"Lopez LR, Dier KJ, Lopez D, et al.: Anti-beta 2-glycoprotein I and antiphosphatidylserine antibodies are predictors of arterial thrombosis in patients with antiphospholipid syndrome. Am J Clin Pathol 2004, 121:142\u2013149.","journal-title":"Am J Clin Pathol"},{"key":"49_CR8","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0889-857X(21)00225-8","volume":"20","author":"MD Lockshin","year":"1994","unstructured":"Lockshin MD: Antiphospholipid antibody syndrome. Rheum Dis Clin North Am 1994, 20:45\u201359.","journal-title":"Rheum Dis Clin North Am"},{"key":"49_CR9","doi-asserted-by":"crossref","first-page":"682","DOI":"10.7326\/0003-4819-112-9-682","volume":"112","author":"PE Love","year":"1990","unstructured":"Love PE, Santoro SA: Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus er y thematosus (SLE) and in non-SLE disorders. Prevalence and clinical significance. Ann Intern Med 1990, 112:682\u2013698.","journal-title":"Ann Intern Med"},{"key":"49_CR10","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1002\/art.1780390903","volume":"39","author":"RAS Roubey","year":"1996","unstructured":"Roubey RAS: Immunology of the-antiphospholipid syndrome. Arthritis Rheum 1996, 39:1444\u20131454.","journal-title":"Arthritis Rheum"},{"key":"49_CR11","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0090-1229(86)90046-2","volume":"41","author":"O Vaarala","year":"1986","unstructured":"Vaarala O, Palosuo T, Kleemola M: Anticardiolipin responses in acute infections. Clin Immunol Immunopathol 1986, 41:8\u201315.","journal-title":"Clin Immunol Immunopathol"},{"key":"49_CR12","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1002\/ajh.2830270408","volume":"27","author":"RT Canso","year":"1988","unstructured":"Canso RT, De Oliviera RM: Chlorpromazine-induced anticardiolipin antibodies and lupus anticoagulant: absence of thrombosis. Am J Hematol 1988, 27:272\u2013275.","journal-title":"Am J Hematol"},{"key":"49_CR13","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/clinids\/18.2.213","volume":"18","author":"J Ordi-Ros","year":"1994","unstructured":"Ordi-Ros J, Selva-O\u2019Callagan A, Monegal-Farran F:Prevalence, significance and specificity of antibodies to phospholipids in Q fever. Clin Infect Dis 1994, 18:213\u2013218.","journal-title":"Clin Infect Dis"},{"key":"49_CR14","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1006\/jaut.2000.0409","volume":"15","author":"M Petri","year":"2000","unstructured":"Petri M: Epidemiology of antiphospholipid antibody syndrome. J Autoimmunity 2000, 15:145\u2013151.","journal-title":"J Autoimmunity"},{"key":"49_CR15","first-page":"175","volume":"24","author":"JF Schved","year":"1994","unstructured":"Schved JF, Dupuy-Fons C, Biron C, et al.: A prospective epidemiological study on the occurrence of antiphospholipid antibody: the Montpellier Antiphospholipid (MAP) Study. Haemostasis 1994, 24:175\u2013182.","journal-title":"Haemostasis"},{"key":"49_CR16","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0002-9343(96)00335-X","volume":"101","author":"PA Merkel","year":"1996","unstructured":"Merkel PA, Chang Y, Pierangeli SS, et al.: The prevalence and clinical associations of anticardiolipin antibodies in a large inception cohort of patients with connective tissue diseases. Am J Med 1996, 101:576\u2013583.","journal-title":"Am J Med"},{"key":"49_CR17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/00005792-199303000-00005","volume":"72","author":"R Cervera","year":"1993","unstructured":"Cervera R, Khamashta MA, Front J, et al.: Systemic lupus erythematosus: clinical and immunologic paterns of disease expression in a cohort of 1,000 patients. Medicine (Baltimore) 1993, 72:113\u2013124.","journal-title":"Medicine (Baltimore)"},{"key":"49_CR18","unstructured":"Del Pino-Montes J, L\u00f3pez-Bernus A, Pozo L, et al.: Antiphospholipid antibodies in early onset rheumatoid arthritis [abstract]. Paper presented at the Annual European Congress of Rheumatology. Berlin, Germany; June 9\u201312, 2004."},{"key":"49_CR19","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/rheumatology\/39.5.481","volume":"39","author":"O Vittecoq","year":"2000","unstructured":"Vittecoq O, Jouen-Beades F, Krzanowska K, et al.: Prospective evaluation of the frequency and clinical significance of antineutrophil cytoplasmic and anticardiolipin antibodies in community cases of patients with rheumatoid arthritis. Rheumatology (Oxford) 2000, 39:481\u2013489.","journal-title":"Rheumatology (Oxford)"},{"key":"49_CR20","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1136\/ard.50.9.599","volume":"50","author":"R Caporali","year":"1991","unstructured":"Caporali R, Ravelli A, De Gennaro F, et al.: Prevalence of anticardiolipin antibodies in juvenile chronic arthritis. Ann Rheum Dis 1991, 50:599\u2013601.","journal-title":"Ann Rheum Dis"},{"key":"49_CR21","first-page":"593","volume":"14","author":"B Seriolo","year":"1996","unstructured":"Seriolo B, Accardo S, Fasciolo D, et al.: Lipoproteins, anticardiolipin antibodies and thrombotic events in rheumatoid arthritis. Clin Exp Rheumatol 1996, 14:593\u2013599.","journal-title":"Clin Exp Rheumatol"},{"key":"49_CR22","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/rheumatology\/39.8.922","volume":"39","author":"D Alarcon-Segovia","year":"2000","unstructured":"Alarcon-Segovia D, Drenkard C: Vasculitis and antiphospholipid syndrome. Rheumatology 2000, 39:922\u2013923.","journal-title":"Rheumatology"},{"key":"49_CR23","first-page":"194","volume":"23","author":"B Seriolo","year":"1996","unstructured":"Seriolo B, Accardo S, Cutolo M: Lipoprotein(a) and other risk factors for thrombosis in rheumatoid arthritis. J Rheumatol 1996, 23:194\u2013196.","journal-title":"J Rheumatol"},{"key":"49_CR24","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1093\/rheumatology\/38.7.675","volume":"38","author":"B Seriolo","year":"1999","unstructured":"Seriolo B, Accardo S, Garnero A, et al.: Anticardiolipin antibodies, free protein S levels and thrombosis: a survey in a selected population of rheumatoid arthritis patients. Rheumatology (Oxford) 1999, 38:675\u2013678.","journal-title":"Rheumatology (Oxford)"},{"key":"49_CR25","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1055\/s-0037-1615380","volume":"80","author":"Heijer M Den","year":"1998","unstructured":"Den Heijer M, Rosendaal FR, Blom HJ, et al.: Hyperhomocysteinemia and venous thrombosis: a meta-analysis. Throm Hoemost 1998, 80:874\u2013877.","journal-title":"Throm Hoemost"},{"key":"49_CR26","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1056\/NEJM199905133401915","volume":"340","author":"M Gaustadnes","year":"1999","unstructured":"Gaustadnes M, Ingersler J, Rudiger N: Prevalence of congenital homocystinuria in Denmark [letter]. N Engl J Med 1999, 340:1513.","journal-title":"N Engl J Med"},{"key":"49_CR27","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/ajcn\/57.1.47","volume":"57","author":"JB Ubbink","year":"1993","unstructured":"Ubbink JB, Vermaak WJ, der MerweA, Becker PJ: Vitamin B12, vitamin B6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr 1993, 57:47\u201353.","journal-title":"Am J Clin Nutr"},{"key":"49_CR28","first-page":"561","volume":"19","author":"B Seriolo","year":"2001","unstructured":"Seriolo B, Fasciolo D, Sulli A, Cutolo M: Homocysteine and antiphospholipid antibodies in rheumatoid arthritis patients: relationships with thrombotic events. Clin Exp Rheumatol 2001, 19:561\u2013564.","journal-title":"Clin Exp Rheumatol"},{"key":"49_CR29","first-page":"1737","volume":"25","author":"R Fijnheer","year":"1998","unstructured":"Fijnheer R, Roest M, Hass FJLM, et al.: Homocysteine, methylenetetrahydrofolate reductase polymorphism, antiphospholipid antibodies, and thromboembolic events in systemic lupus erythematosus: a retrospective cohort study. J Rheumatol 1998, 25:1737\u20131742.","journal-title":"J Rheumatol"},{"key":"49_CR30","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/art.1780370408","volume":"37","author":"F Wolfe","year":"1994","unstructured":"Wolfe F, Mitchell DM, Sibley JT, et al.: The mortality of rheumatoid arthritis. Arthritis Rheum 1994, 37:481\u2013494.","journal-title":"Arthritis Rheum"},{"key":"49_CR31","first-page":"757","volume":"16","author":"RR Buchanan","year":"1989","unstructured":"Buchanan RR, Wardlaw JR, Riglar AG, et al.: Antiphospholipid antibodies in the connective tissue diseases: their relation to the antiphospholipid syndrome and forme fruste disease. J Rheumatol 1989, 16:757\u2013761.","journal-title":"J Rheumatol"},{"key":"49_CR32","first-page":"351","volume":"16","author":"A Saraux","year":"1998","unstructured":"Saraux A, Bendaoud B, Guedes C, et al.: Antiphospholipid antibodies and Raynaud\u2019s phenomenon in rheumatoid arthritis. Clin Exp Rheumatol 1998, 16:351.","journal-title":"Clin Exp Rheumatol"},{"key":"49_CR33","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1365-2133.1994.tb08456.x","volume":"131","author":"P Wolf","year":"1994","unstructured":"Wolf P, Gretler J, Aglas F, et al.: Anticardiolipin antibodies in rheumatoid arthritis: their relation to rheumatoid nodules and cutaneous vascular manifestations. Br J Dermatol 1994, 131:48\u201351. largest study (173 patients) examining the prevalence of aCL antibodies in R A. The investigators also assessed the clinical relevance and the relationship of those antibodies to skin manifestations","journal-title":"Br J Dermatol"},{"key":"49_CR34","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1093\/rheumatology\/26.5.346","volume":"26","author":"A Keane","year":"1987","unstructured":"Keane A, Woods R, Dowding V, et al.: Anticardiolipin antibodies in rheumatoid arthritis. Br J Rheumatol 1987, 26:346\u2013350.","journal-title":"Br J Rheumatol"},{"key":"49_CR35","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/art.1780300705","volume":"30","author":"JG Fort","year":"1987","unstructured":"Fort JG, Cowchock FS, Abruzzo JL, Smith JB: Anticardiolipin antibodies in patients with rheumatic diseases. Arthritis Rheum 1987, 30:752\u2013760.","journal-title":"Arthritis Rheum"},{"key":"49_CR36","first-page":"47","volume":"69","author":"SA Rabee","year":"1994","unstructured":"Rabee SA, Sallam AM, Ayuoub NM, el Kholy EE: Anticardiolipin antibodies in rheumatoid arthritis. J Egypt Public Health Assoc 1994, 69:47\u201363.","journal-title":"J Egypt Public Health Assoc"},{"key":"49_CR37","first-page":"875","volume":"29","author":"S Wallberg-Jonsson","year":"2002","unstructured":"Wallberg-Jonsson S, Cvetkovic JT, Sundqvist KG, et al.:Activation of the immune system and infiammatory activity in relation to markers of atherothrombotic disease and atherosclerosis in rheumatoid arthritis. J Rheumatol 2002, 29:875\u2013882.","journal-title":"J Rheumatol"},{"key":"49_CR38","unstructured":"Del Pino-Montes J, L\u00f3pez-Bernus A, Belhassen M, et al.: Resence of anticardiolipin antibodies (aCL) in patients with early-onset rheumatoid arthritis (R A) [abstract]. Paper presented at the Annual European Congress of Rheumatolog y. Berlin, Germany; June 9\u201312, 2004."},{"key":"49_CR39","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1093\/ije\/23.3.545","volume":"23","author":"J Coste","year":"1994","unstructured":"Coste J, Jougla E: Mortality from rheumatoid arthritis in France, 1970\u20131990. Int J Epidemiol 1994, 23:545\u2013552.","journal-title":"Int J Epidemiol"},{"key":"49_CR40","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0140-6736(86)92258-0","volume":"1","author":"A Hamsten","year":"1986","unstructured":"Hamsten A, Norberg R, Bjorkholm M, et al.: Antibodies to cardiolipin in young survivors of myocardial infarction: an association with recurrent cardiovascular events. Lancet 1986, 1:113\u2013116.","journal-title":"Lancet"},{"key":"49_CR41","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/S0140-6736(86)92004-0","volume":"2","author":"KE Morton","year":"1986","unstructured":"Morton KE, Gavaghan TP, Krilis SA, et al.: Coronary artery bypass graft failure-an autoimmune phenomenon? Lancet 1986, 2:1353\u20131357.","journal-title":"Lancet"},{"key":"49_CR42","unstructured":"Sherer Y, Gerli R, Vaudo G, et al.: Thickened carotid artery intima-media in rheumatoid arthritis is associated with anti-cardiolipin antibodies [abstract]. Paper presented at the Annual European Congress of Rheumatology. Berlin, Germany; June 9\u201312, 2004."},{"key":"49_CR43","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1056\/NEJM199901283400401","volume":"340","author":"ME Weinblatt","year":"1999","unstructured":"Weinblatt ME, Kremer JM, Bankhurst AD, et al.: A trial of etanercept a recombinant tumor necrosis factor receptor: Fc fusion protein in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 1999, 340:253\u2013259.","journal-title":"N Engl J Med"},{"key":"49_CR44","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1056\/NEJM199707173370301","volume":"337","author":"LW Moreland","year":"1997","unstructured":"Moreland LW, Baumgartner SW, Schiff MH, et al.:Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 1997, 337:141\u2013147.","journal-title":"N Engl J Med"},{"key":"49_CR45","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1136\/ard.61.4.358","volume":"61","author":"G Ferraccioli","year":"2002","unstructured":"Ferraccioli G, Mecchia F, Di Poi E, Fabris M: Anticardiolipin antibodies in rheumatoid patients treated with etanercept or conventional combination therapy: direct and indirect evidence for a possible association with infections. Ann Rheum Dis 2002, 61:358\u2013361.","journal-title":"Ann Rheum Dis"},{"key":"49_CR46","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1136\/ard.2003.018093","volume":"63","author":"T Jonsdottir","year":"2004","unstructured":"Jonsdottir T, Forslid J, van Vollenhoven A, et al.: Treatment with tumour necrosis factor alpha antagonists in patients with rheumatoid arthritis induces anticardiolipin antibodies. Ann Rheum Dis 2004, 63:1075\u20131078. s is the largest published study (121 patients) evaluating the frequency and clinical impact of aCL antibodies in patients with RA treated with TNF-\u00e1 inhibitors.","journal-title":"Ann Rheum Dis"},{"key":"49_CR47","unstructured":"G\u00f3mez-Puerta JA, Hern\u00e1ndez MV, Reverter JC, et al.: Anticardiolipin antibodies in patients with rheumatoid arthritis and spondyloarthopathies treated with inf liximab [abstract]. Paper presented at the Annual European Congress of Rheumatolog y. Berlin, Germany; June 9\u201312, 2004."},{"key":"49_CR48","doi-asserted-by":"crossref","first-page":"R264","DOI":"10.1186\/ar1173","volume":"6","author":"F Bobbio-Pallavicini","year":"2004","unstructured":"Bobbio-Pallavicini F, Alpini C, Caporali R, et al.:Autoantibody profile in rheumatoid arthritis during long-term infliximab treatment. Arthritis Res Ther 2004, 6:R264-R272.","journal-title":"Arthritis Res Ther"},{"key":"49_CR49","doi-asserted-by":"crossref","first-page":"R535","DOI":"10.1186\/ar1440","volume":"6","author":"C Ferraro-Peyret","year":"2004","unstructured":"Ferraro-Peyret C, Coury F, Tebib JG, et al.: Infliximab therapy in rheumatoid arthritis and ankylosing spondylitis- induced specific antinuclear and antiphospholipid autoantibodies without autoimmune clinical manifestations: a two-year prospective study. Arthritis Res Ther 2004, 6:R535-R543.","journal-title":"Arthritis Res Ther"},{"key":"49_CR50","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1136\/ard.2003.018093","volume":"63","author":"T Jonsdottir","year":"2004","unstructured":"Jonsdottir T, Forslid J, van Vollenhoven A, et al.: Treatment with tumour necrosis factor alpha antagonists in patients with rheumatoid arthritis induces anticardiolipin antibodies. Ann Rheum Dis 2004, 63:1075\u20131078.","journal-title":"Ann Rheum Dis"},{"key":"49_CR51","doi-asserted-by":"crossref","first-page":"499","DOI":"10.3109\/07853899709007474","volume":"29","author":"P Isom\u00e3ki","year":"1997","unstructured":"Isom\u00e3ki P, Punnonen J: Pro- and anti-inflammatory cytokines in rheumatoid arthritis. Ann Med 1997, 29:499\u2013507.","journal-title":"Ann Med"},{"key":"49_CR52","first-page":"217","volume":"13","author":"M Cutolo","year":"1995","unstructured":"Cutolo M, Sulli A, Seriolo B, Masi MT: Estrogens, the immune response and autoimmunity. Clin Exp Rheumatol 1995, 13:217\u2013226.","journal-title":"Clin Exp Rheumatol"},{"key":"49_CR53","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1093\/rheumatology\/38.11.1159","volume":"38","author":"B Seriolo","year":"1999","unstructured":"Seriolo B, Cutolo M, Garnero A, Accardo S: Relationships between serum 17 beta-oestradiol and anticardiolipin antibody concentrations in female patients with rheumatoid arthritis. Rheumatology (Oxford) 1999, 38:1159\u20131161.","journal-title":"Rheumatology (Oxford)"},{"key":"49_CR54","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1749-6632.1999.tb07635.x","volume":"876","author":"B Seriolo","year":"1999","unstructured":"Seriolo B, Accardo S, Garnero A, et al.: Association between anticardiolipin antibody positivity and increased 17-beta-estradiol levels in premenopausal women with rheumatoid arthritis. Ann N Y Acad Sci 1999, 876:159\u2013163.","journal-title":"Ann N Y Acad Sci"},{"key":"49_CR55","doi-asserted-by":"crossref","first-page":"27S","DOI":"10.1177\/096120339400400107","volume":"4","author":"J Kaburaki","year":"1995","unstructured":"Kaburaki J, Kuwana M, Yamamoto M, et al.: Disease distribution of beta 2-glycoprotein 1-dependent anticardiolipin antibodies in rheumatic diseases. Lupus 1995, 4:27S-31S.","journal-title":"Lupus"},{"key":"49_CR56","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1055\/s-0038-1646310","volume":"68","author":"M Jurado","year":"1992","unstructured":"Jurado M, Paramo JA, Gutierrez-Pimentel M, Rocha E:Fibrinolytic potential and antiphospholipid antibodies in systemic lupus er ythematosus and other connective tissue disorders. Thromb Haemost 1992, 68:516\u2013520.","journal-title":"Thromb Haemost"},{"key":"49_CR57","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0002-9343(96)00335-X","volume":"101","author":"PA Merkel","year":"1996","unstructured":"Merkel PA, Chang Y, Pierangeli SS, et al.: The prevalence and clinical associations of anticardiolipin antibodies in a large inception cohort of patients with connective tissue diseases. Am J Med 1996, 101:576\u2013583.","journal-title":"Am J Med"},{"key":"49_CR58","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1136\/ard.61.1.85","volume":"61","author":"A Ambrozic","year":"2002","unstructured":"Ambrozic A, Bozic B, Hojnik M, et al.: Antiphospholipid antibodies and rheumatoid arthritis. Ann Rheum Dis 2002, 61:85\u201386.","journal-title":"Ann Rheum Dis"},{"key":"49_CR59","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3233\/HAB-2003-12301","volume":"12","author":"I Marai","year":"2003","unstructured":"Marai I, Gilburd B, Blank M, Shoenfeld Y: Anti-cardiolipin and anti-beta2-glycoprotein I (beta2GP-I) antibody assays as screening for anti-phospholipid syndrome. Hum Antibodies 2003, 12:57\u201362.","journal-title":"Hum Antibodies"},{"key":"49_CR60","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1196\/annals.1361.071","volume":"1051","author":"Y Sherer","year":"2005","unstructured":"Sherer Y, Gerli R, Vaudo G, et al.: Prevalence of antiphospholipid and antioxidized low-density lipoprotein antibodies in rheumatoid arthritis. Ann N Y Acad Sci 2005, 1051:299\u2013303.","journal-title":"Ann N Y Acad Sci"},{"key":"49_CR61","first-page":"199","volume":"23","author":"N Assous","year":"2005","unstructured":"Assous N, Allanore Y, Batteux F, et al.: Prevalence of antiphospholipid antibodies in systemic sclerosis and association with primitive pulmonary arterial hypertension and endothelial injury. Clin Exp Rheumatol 2005, 23:199\u2013204.","journal-title":"Clin Exp Rheumatol"}],"container-title":["Current Rheumatology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11926-006-0049-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11926-006-0049-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11926-006-0049-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,14]],"date-time":"2021-08-14T13:59:35Z","timestamp":1628949575000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11926-006-0049-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["49"],"URL":"https:\/\/doi.org\/10.1007\/s11926-006-0049-8","relation":{},"ISSN":["1523-3774","1534-6307"],"issn-type":[{"value":"1523-3774","type":"print"},{"value":"1534-6307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}