{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:27:26Z","timestamp":1791214046444,"version":"4.1.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Rheumatol Rep"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1007\/s11926-012-0248-4","type":"journal-article","created":{"date-parts":[[2012,3,31]],"date-time":"2012-03-31T06:41:34Z","timestamp":1333176094000},"page":"244-251","source":"Crossref","is-referenced-by-count":34,"title":["Exercise in Inflammatory Myopathies, Including Inclusion Body Myositis"],"prefix":"10.1007","volume":"14","author":[{"given":"Helene","family":"Alexanderson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,4,1]]},"reference":[{"key":"248_CR1","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1517\/14656560902913815","volume":"10","author":"GJ Hengstman","year":"2009","unstructured":"Hengstman GJ, van den Hoogen FH, van Engelen BG. Treatment of the inflammatory myopathies: update and practical recommendations. Expert Opin Pharmacother. 2009;10:1183\u201390.","journal-title":"Expert Opin Pharmacother"},{"key":"248_CR2","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/rheumatology\/ken441","volume":"48","author":"MO Harris-Love","year":"2009","unstructured":"Harris-Love MO, et al. Distribution and severity of weakness among patients with polymyositis, dermatomyositis and juvenile dermatomyositis. Rheumatology (Oxford). 2009;48:134\u20139.","journal-title":"Rheumatology (Oxford)"},{"key":"248_CR3","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/rheumatology\/keq356","volume":"50","author":"M Regardt","year":"2011","unstructured":"Regardt M, et al. Patients with polymyositis or dermatomyositis have reduced grip force and health-related quality of life in comparison with reference values: an observational study. Rheumatology (Oxford). 2011;50:578\u201385.","journal-title":"Rheumatology (Oxford)"},{"key":"248_CR4","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/art.21715","volume":"55","author":"H Alexanderson","year":"2006","unstructured":"Alexanderson H, et al. Functional index 2: validity and reliability of a disease-specific measure of impairment in patients with polymyositis and dermatomyositis. Arthritis Rheum. 2006;55:114\u201322.","journal-title":"Arthritis Rheum"},{"key":"248_CR5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/ard.2003.006122","volume":"63","author":"M Fathi","year":"2004","unstructured":"Fathi M, et al. Interstitial lung disease, a common manifestation of newly diagnosed polymyositis and dermatomyositis. Ann Rheum Dis. 2004;63:297\u2013301.","journal-title":"Ann Rheum Dis"},{"key":"248_CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0003-9993(00)90212-0","volume":"81","author":"GF Wiesinger","year":"2000","unstructured":"Wiesinger GF, et al. Aerobic capacity in adult dermatomyositis\/polymyositis patients and healthy controls. Arch Phys Med Rehabil. 2000;81:1\u20135.","journal-title":"Arch Phys Med Rehabil"},{"key":"248_CR7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/rheumatology\/keh404","volume":"44","author":"A Ponyi","year":"2005","unstructured":"Ponyi A, et al. Functional outcome and quality of life in adult patients with idiopathic inflammatory myositis. Rheumatology (Oxford). 2005;44:83\u20138.","journal-title":"Rheumatology (Oxford)"},{"key":"248_CR8","first-page":"940","volume":"27","author":"P Nyberg","year":"2000","unstructured":"Nyberg P, et al. Increased expression of interleukin 1 alpha and MHC class I in muscle tissue of patients with chronic, inactive polymyositis and dermatomyositis. J Rheumatol. 2000;27:940\u20138.","journal-title":"J Rheumatol"},{"key":"248_CR9","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1002\/art.10140","volume":"46","author":"P Englund","year":"2002","unstructured":"Englund P, et al. Interleukin-1 alpha expression in capillaries and major histocompatability complex I expression in type II muscle fibers from polymyositis and dermatomyositis patients: important pathogenic features independent of inflammatory cell clusters in muscle tissue. Arthritis Rheum. 2002;46:1044\u201355.","journal-title":"Arthritis Rheum"},{"key":"248_CR10","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1093\/brain\/awf163","volume":"125","author":"G Cea","year":"2002","unstructured":"Cea G, et al. Reduced oxidative phosphorylation and proton efflux suggest reduced capillary blood supply in skeletal muscle of patients with dermatomyositis and polymyositis: a quantitative 31p-magnetic resonance spectroscopy and MRI-study. Brain. 2002;125:1635\u201345.","journal-title":"Brain"},{"key":"248_CR11","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/art.1780380111","volume":"38","author":"JH Park","year":"1995","unstructured":"Park JH, et al. Use of magnetic resonance imaging and P-31 magnetic resonance spectroscopy to detect and quantify muscle dysfunction in the amyopathic and myopathic variants of dermatomyositis. Arthritis Rheum. 1995;38:68\u201377.","journal-title":"Arthritis Rheum"},{"key":"248_CR12","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1097\/BOR.0b013e3282efdc7c","volume":"19","author":"V Askanas","year":"2007","unstructured":"Askanas V, Engel WK. Inclusion-body myositis, a multifactorial muscle disease associated with aging: current concepts of pathogenesis. Curr Opin Rheumatol. 2007;19:550\u20139.","journal-title":"Curr Opin Rheumatol"},{"key":"248_CR13","unstructured":"Lindberg C, Oldfors A. Prognosis and prognostic factors in sporadic inclusion body myositis. Acta Neurol Scand. 2011. doi: 10.1111\u2044j.1600-0404.2011.01584.x ."},{"key":"248_CR14","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1136\/jnnp.2009.183863","volume":"81","author":"R Sadjadi","year":"2011","unstructured":"Sadjadi R, et al. What determines quality of life in inclusion body myositis. J Neurol Neurosurg Psychiatry. 2011;81:1164\u20136.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"248_CR15","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.berh.2009.07.007","volume":"5","author":"L Wedderburn","year":"2009","unstructured":"Wedderburn L, Rider LG. Juvenile dermatomyositis: new developments in pathogenesis, assessment and treatment. Best Pract Res Clin Rheumatol. 2009;5:665\u201378.","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"248_CR16","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1002\/acr.20203","volume":"62","author":"H Sanner","year":"2010","unstructured":"Sanner H, et al. Longterm muscular outcome and predisposing and prognostic factors in juvenile dermatomyositis: a case\u2013control study. Arthritis Care Res. 2010;62:1103\u201311.","journal-title":"Arthritis Care Res"},{"key":"248_CR17","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1139\/h03-063","volume":"28","author":"BE Drinkard","year":"2003","unstructured":"Drinkard BE, et al. Fitness as a determinant of the oxygen uptake\/work rate slope in healthy children and children with inflammatory myopathy. Can J Appl Physiol. 2003;28:888\u201397.","journal-title":"Can J Appl Physiol"},{"key":"248_CR18","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/art.10237","volume":"47","author":"JE Hicks","year":"2002","unstructured":"Hicks JE, et al. Decreased aerobic capacity in children with dermatomyositis. Arthritis Rheum. 2002;47:118\u201323.","journal-title":"Arthritis Rheum"},{"key":"248_CR19","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1093\/rheumatology\/ker256","volume":"50","author":"Y Butbul Aviel","year":"2011","unstructured":"Butbul Aviel Y, et al. Sleep and fatigue and the relationship to pain, disease activity and quality of life in juvenile idiopathic arthritis and juvenile dermatomyositis. Rheumatology (Oxford). 2011;50:2051\u201360.","journal-title":"Rheumatology (Oxford)"},{"key":"248_CR20","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1093\/rheumatology\/ker292","volume":"50","author":"GA Habers","year":"2011","unstructured":"Habers GA, Takken T. Safety and efficacy of exercise training in patients with an idiopathic inflammatory myopathy- a systematic review. Rheumatology (Oxford). 2011;50:2113\u201324.","journal-title":"Rheumatology (Oxford)"},{"key":"248_CR21","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/(SICI)1097-4598(199710)20:10<1242::AID-MUS6>3.0.CO;2-C","volume":"20","author":"SA Spector","year":"1997","unstructured":"Spector SA, et al. Safety and efficacy of strength training in patients with sporadic inclusion body myositis. Muscle Nerve. 1997;20:1242\u20138.","journal-title":"Muscle Nerve"},{"key":"248_CR22","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/16501970306110","volume":"35","author":"S Arnardottir","year":"2003","unstructured":"Arnardottir S, et al. Sporadic inclusion body myositis: pilot study on the effects of a home exercise program in muscle function, histopathology and inflammatory reaction. J Rehabil Med. 2003;35:31\u20135.","journal-title":"J Rehabil Med"},{"key":"248_CR23","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/art.21185","volume":"53","author":"M Harris-Love","year":"2005","unstructured":"Harris-Love M. Safety and efficacy of submaximal eccentric strength training for a subject with polymyositis. Arthritis Rheum. 2005;53:471\u20134.","journal-title":"Arthritis Rheum"},{"key":"248_CR24","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1249\/MSS.0b013e3181b18fb8","volume":"42","author":"B Gualano","year":"2010","unstructured":"\u2022 Gualano B, et al. Resistance training with vascular occlusion in inclusion body myositis: a case study. Med Sci Sports Exerc. 2010;42:250\u20134. This case report describes improved quadriceps function following a 52-week submaximal exercise program during vascular occlusion.","journal-title":"Med Sci Sports Exerc"},{"key":"248_CR25","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/CND.0b013e3181237291","volume":"8","author":"GL Johnson","year":"2007","unstructured":"Johnson GL, et al. The effectiveness of an individualized, home-based functional exercise program for patients with sporadic inclusion body myositis. Clin Neuromusc Dis. 2007;8:187\u201394.","journal-title":"Clin Neuromusc Dis"},{"key":"248_CR26","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1097\/CND.0b013e3181a23c86","volume":"10","author":"LG Johnson","year":"2009","unstructured":"\u2022 Johnson LG, et al. Improvement in aerobic capacity after an exercise program in sporadic inclusion body myositis. Clin Neuromusc Dis. 2009;10:178\u201384. This was the first study to evaluate aerobic exercise in inclusion body myositis, suggesting improved aerobic capacity and muscle function.","journal-title":"Clin Neuromusc Dis"},{"key":"248_CR27","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00415-003-0993-4","volume":"250","author":"TD Jeppesen","year":"2003","unstructured":"Jeppesen TD, Olsen D, Vissing J. Cycle ergometry is not a sensitive diagnostic test for mitochondrial myopathy. J Neurol. 2003;250:293\u20139.","journal-title":"J Neurol"},{"key":"248_CR28","first-page":"1399","volume":"20","author":"JE Hicks","year":"1993","unstructured":"Hicks JE, et al. Isometric exercises increases strength and does not produce sustained creatine phosphokinase in a patient with polymyositis. J Rheumatol. 1993;20:1399\u2013401.","journal-title":"J Rheumatol"},{"key":"248_CR29","first-page":"1340","volume":"20","author":"A Escalante","year":"1993","unstructured":"Escalante A, Miller L, Beardmore TD. Resistive exercise in the rehabilitation of polymyositis\/dermatomyositis. J Rheumatol. 1993;20:1340\u20134.","journal-title":"J Rheumatol"},{"key":"248_CR30","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1093\/rheumatology\/37.2.196","volume":"37","author":"GF Wiesinger","year":"1998","unstructured":"Wiesinger GF, et al. Improvement of physical fitness and muscle strength in polymyositis\/dermatomyositis patients by a training programme. Br J Rheumatol. 1998;37:196\u2013200.","journal-title":"Br J Rheumatol"},{"key":"248_CR31","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1093\/rheumatology\/37.12.1338","volume":"37","author":"GF Wiesinger","year":"1998","unstructured":"Wiesinger GF, et al. Benefit of 6-months long-term physical training in polymyositis\/dermatomyositis patients. Br J Rheumatol. 1998;37:1338\u201342.","journal-title":"Br J Rheumatol"},{"key":"248_CR32","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0031-9406(05)60764-X","volume":"87","author":"S Heikkil\u00e4","year":"2001","unstructured":"Heikkil\u00e4 S, et al. Rehabilitation in myositis. Physiother. 2001;87:301\u20139.","journal-title":"Physiother"},{"key":"248_CR33","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1191\/0269215503cr572oa","volume":"17","author":"C Varj\u00fa","year":"2003","unstructured":"Varj\u00fa C, et al. The effect of physical exercise following acute disease exacerbation in patients with dermato\/polymyositis. Clin Rehabil. 2003;17:83\u20137.","journal-title":"Clin Rehabil"},{"key":"248_CR34","first-page":"349","volume":"13","author":"M Kroll","year":"1986","unstructured":"Kroll M, Otis J, Kagen L. Serum enzyme, myoglobin and muscle strength relationships in polymyositis and dermatomyositis. J Rheumatol. 1986;13:349\u201355.","journal-title":"J Rheumatol"},{"key":"248_CR35","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1093\/rheumatology\/38.7.608","volume":"38","author":"H Alexanderson","year":"1999","unstructured":"Alexanderson H, Stenstr\u00f6m CH, Lundberg IE. Safety of a home exercise programme in patients with polymyositis and dermatomyositis: a pilot study. Rheumatology (Oxford). 1999;38:608\u201311.","journal-title":"Rheumatology (Oxford)"},{"key":"248_CR36","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1080\/030097400447679","volume":"29","author":"H Alexanderson","year":"2000","unstructured":"Alexanderson H, et al. The safety of a resistive home exercise program in patients with recent onset active polymyositis or dermatomyositis. Scand J Rheumatol. 2000;29:295\u2013301.","journal-title":"Scand J Rheumatol"},{"key":"248_CR37","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/art.22996","volume":"57","author":"M Dastmalchi","year":"2007","unstructured":"Dastmalchi M, et al. Effect of physical training in proportion of slow-twitch type I muscle fibers. A novel non-immune-mediated mechanism for muscle impairment in polymyositis or dermatomyositis. Arthritis Rheum. 2007;57:1303\u201310.","journal-title":"Arthritis Rheum"},{"key":"248_CR38","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1002\/art.22687","volume":"57","author":"YL Chung","year":"2007","unstructured":"Chung YL, et al. Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacological treatment: six-month double-blind randomized placebo-controlled trial. Arthritis Rheum. 2007;57:694\u2013702.","journal-title":"Arthritis Rheum"},{"key":"248_CR39","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1002\/art.22780","volume":"57","author":"H Alexanderson","year":"2007","unstructured":"Alexanderson H, et al. Benefits of intensive resistance training in patients with chronic polymyositis or dermatomyositis. Arthritis Rheum. 2007;57:768\u201377.","journal-title":"Arthritis Rheum"},{"key":"248_CR40","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1002\/art.20349","volume":"50","author":"LG Rider","year":"2004","unstructured":"Rider LG, et al. International consensus on preliminary definitions of improvement in adult and juvenile myositis. Arthritis Rheum. 2004;50:2281\u201390.","journal-title":"Arthritis Rheum"},{"key":"248_CR41","doi-asserted-by":"crossref","first-page":"455","DOI":"10.2119\/molmed.2010.00016","volume":"16","author":"GA Nader","year":"2010","unstructured":"\u2022\u2022 Nader GA, et al. A longitudinal, integrated, clinical, histological and mRNA profiling study of resistance exercise in myositis. Mol Med. 2010;16:455\u201364. This study suggests that resistance exercise may reduce inflammation and fibrosis in muscle tissue of patients with polymyositis and dermatomyositis in chronic, established disease.","journal-title":"Mol Med"},{"key":"248_CR42","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1186\/1471-2474-11-270","volume":"11","author":"C Omori","year":"2010","unstructured":"\u2022 Omori C, et al. Responsiveness to exercise training in juvenile dermatomyositis: a twin case study. BMC Muskuloskeletal Dis. 2010;11:270. This case report is the only publication to describe tolerance of exercise over weeks to months in a patient with juvenile dermatomyositis.","journal-title":"BMC Muskuloskeletal Dis"},{"key":"248_CR43","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1002\/art.21332","volume":"53","author":"SM Maillard","year":"2005","unstructured":"Maillard SM, et al. Quantitative assessment of the effects of a single exercise session on muscles in juvenile dermatomyositis. Arthritis Rheum. 2005;53:558\u201364.","journal-title":"Arthritis Rheum"},{"key":"248_CR44","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/art.23250","volume":"59","author":"T Takken","year":"2008","unstructured":"Takken T, et al. Responsiveness of exercise parameters in children with inflammatory myositis. Arthritis Rheum. 2008;59:59\u201364.","journal-title":"Arthritis Rheum"},{"key":"248_CR45","first-page":"1075","volume":"39","author":"T Takken","year":"2003","unstructured":"Takken T, et al. Aerobic capacity in patients with juvenile dermatomyositis. J Rheumatol. 2003;39:1075\u201380.","journal-title":"J Rheumatol"},{"key":"248_CR46","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/art.21066","volume":"53","author":"T Takken","year":"2005","unstructured":"Takken T, van der Net J, Helders PJ. Anaerobic exercise capacity in patients with juvenile onset idiopathic inflammatory myopathies. Arthritis Rheum. 2005;53:173\u20137.","journal-title":"Arthritis Rheum"},{"key":"248_CR47","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/BOR.0b013e328335d1a2","volume":"22","author":"AR Long","year":"2010","unstructured":"Long AR, Rouster-Stevens KA. The role of exercise therapy in the management of juvenile idiopathic arthritis. Curr Opin Rheumatol. 2010;22:213\u20137.","journal-title":"Curr Opin Rheumatol"}],"container-title":["Current Rheumatology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11926-012-0248-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11926-012-0248-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11926-012-0248-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T00:49:58Z","timestamp":1559436598000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11926-012-0248-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,1]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["248"],"URL":"https:\/\/doi.org\/10.1007\/s11926-012-0248-4","relation":{},"ISSN":["1523-3774","1534-6307"],"issn-type":[{"value":"1523-3774","type":"print"},{"value":"1534-6307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,1]]}}}