{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T16:07:04Z","timestamp":1787587624227,"version":"build-2736575974"},"reference-count":87,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Rheumatol Rep"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1007\/s11926-017-0627-y","type":"journal-article","created":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T01:20:30Z","timestamp":1485739230000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Interfacial Adipose Tissue in Systemic Sclerosis"],"prefix":"10.1007","volume":"19","author":[{"given":"Ilja L.","family":"Kruglikov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,1,30]]},"reference":[{"issue":"5","key":"627_CR1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.autrev.2010.09.015","volume":"10","author":"J Wei","year":"2011","unstructured":"Wei J et al. Fibrosis in systemic sclerosis: emerging concepts and implications for targeted therapy. Autoimmun Rev. 2011;10(5):267\u201375.","journal-title":"Autoimmun Rev"},{"issue":"1","key":"627_CR2","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/nrrheum.2011.149","volume":"8","author":"S Bhattacharyya","year":"2012","unstructured":"Bhattacharyya S, Wei J, Varga J. Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities. Nat Rev Rheumatol. 2012;8(1):42\u201354.","journal-title":"Nat Rev Rheumatol"},{"issue":"6","key":"627_CR3","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/BOR.0000000000000217","volume":"27","author":"S Ebmeier","year":"2015","unstructured":"Ebmeier S, Horsley V. Origin of fibrosing cells in systemic sclerosis. Curr Opin Rheumatol. 2015;27(6):555\u201362.","journal-title":"Curr Opin Rheumatol"},{"issue":"2","key":"627_CR4","first-page":"156","volume":"40","author":"A Olewicz-Gawlik","year":"2015","unstructured":"Olewicz-Gawlik A et al. Circulating adipokines and organ involvement in patients with systemic sclerosis. Acta Reumatol Port. 2015;40(2):156\u201362.","journal-title":"Acta Reumatol Port"},{"key":"627_CR5","doi-asserted-by":"publisher","DOI":"10.1007\/s00393-016-0172-5","author":"YH Lee","year":"2016","unstructured":"Lee YH, Song GG. Meta-analysis of circulating adiponectin, leptin, and resistin levels in systemic sclerosis. Z Rheumatol. 2016. doi: 10.1007\/s00393-016-0172-5 .","journal-title":"Z Rheumatol"},{"issue":"6","key":"627_CR6","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1160\/TH10-02-0101","volume":"104","author":"Y Kanno","year":"2010","unstructured":"Kanno Y et al. Urokinase-type plasminogen activator receptor is associated with the development of adipose tissue. Thromb Haemost. 2010;104(6):1124\u201332.","journal-title":"Thromb Haemost"},{"issue":"4","key":"627_CR7","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1002\/art.38990","volume":"67","author":"RG Marangoni","year":"2015","unstructured":"\u2022\u2022 Marangoni RG et al. Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors. Arthritis Rheumatol. 2015;67(4):1062\u201373. Myofibroblasts in dermis can be produced from adiponectin-positive intradermal progenitors. This process was termed adipocytes-myofibroblast transition and it should be sufficiently involved in dermal sclerosis.","journal-title":"Arthritis Rheumatol"},{"issue":"3","key":"627_CR8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1293\/tox.23.133","volume":"23","author":"A Sayama","year":"2010","unstructured":"Sayama A et al. Morphological and biochemical changes during aging and photoaging of the skin of C57BL\/6J mice. J Toxicol Pathol. 2010;23(3):133\u20139.","journal-title":"J Toxicol Pathol"},{"issue":"7","key":"627_CR9","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.18632\/aging.100999","volume":"8","author":"IL Kruglikov","year":"2016","unstructured":"Kruglikov IL, Scherer PE. Skin aging: are adipocytes the next target? Aging. 2016;8(7):1457\u201369.","journal-title":"Aging"},{"issue":"3","key":"627_CR10","doi-asserted-by":"crossref","first-page":"73","DOI":"10.4252\/wjsc.v8.i3.73","volume":"8","author":"A Becker De","year":"2016","unstructured":"De Becker A, van Riet I. Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy? World J Stem Cell. 2016;8(3):73\u201387.","journal-title":"World J Stem Cell"},{"key":"627_CR11","doi-asserted-by":"crossref","first-page":"11674","DOI":"10.1038\/ncomms11674","volume":"7","author":"T Zhang","year":"2016","unstructured":"\u2022 Zhang T et al. CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment. Nat Commun. 2016;7:11674. Adipose stromal cells can be mobilized from adipose tissue through the mechanism of chemotaxis.","journal-title":"Nat Commun"},{"issue":"1","key":"627_CR12","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1186\/s12967-015-0555-4","volume":"13","author":"AF Rolle Le","year":"2015","unstructured":"Le Rolle AF et al. The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts. J Transl Med. 2015;13(1):199.","journal-title":"J Transl Med"},{"issue":"11","key":"627_CR13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049278","volume":"7","author":"M Gharaee-Kermani","year":"2012","unstructured":"Gharaee-Kermani M et al. CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosis. PLoS One. 2012;7(11), e49278.","journal-title":"PLoS One"},{"key":"627_CR14","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/s13075-016-1054-6","volume":"18","author":"RB Christmann","year":"2016","unstructured":"\u2022 Christmann RB et al. MiR-155 in the progression of lung fibrosis in systemic sclerosis. Arthritis Res Ther. 2016;18:155. MicroRNA-155 is involved in pulmonary fibrosis. Mice with deficiency of this MicroRNA develop significantly milder bleomycin-induced pulmonary fibrosis.","journal-title":"Arthritis Res Ther"},{"key":"627_CR15","doi-asserted-by":"crossref","first-page":"20314","DOI":"10.1038\/srep20314","volume":"6","author":"Q Yan","year":"2016","unstructured":"\u2022 Yan Q et al. Targeting miR-155 to treat experimental scleroderma. Sci Rep. 2016;6:20314. Mir-155 deficient mice are resistent zu bleomycin-induced skin fibrosis.","journal-title":"Sci Rep"},{"issue":"3","key":"627_CR16","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.bbrc.2011.09.131","volume":"414","author":"S Liu","year":"2011","unstructured":"Liu S, Yang Y, Wu J. TNF\u03b1-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors. Biochem Biophys Res Commun. 2011;414(3):618\u201324.","journal-title":"Biochem Biophys Res Commun"},{"key":"627_CR17","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1038\/ncomms2742","volume":"4","author":"Y Chen","year":"2013","unstructured":"Chen Y et al. MiR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit. Nat Commun. 2013;4:1769.","journal-title":"Nat Commun"},{"issue":"7","key":"627_CR18","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1242\/dev.087593","volume":"140","author":"BA Schmidt","year":"2013","unstructured":"Schmidt BA, Horsley V. Intradermal adipocytes mediate fibroblast recruitment during skin wound healing. Develop. 2013;140(7):1517\u201327.","journal-title":"Develop"},{"key":"627_CR19","doi-asserted-by":"publisher","unstructured":"Kruglikov IL, Scherer PE, Wollina U. Are dermal adipocytes involved in psoriasis? Exper Dermatol. 2016;25:doi: 10.1111\/exd.12996 .","DOI":"10.1111\/exd.12996"},{"key":"627_CR20","doi-asserted-by":"crossref","first-page":"10230","DOI":"10.1038\/ncomms10230","volume":"7","author":"V Laurent","year":"2016","unstructured":"Laurent V et al. Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity. Nat Commun. 2016;7:10230.","journal-title":"Nat Commun"},{"issue":"1","key":"627_CR21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1001\/archderm.1972.01620040031005","volume":"105","author":"R Fleischmajer","year":"1972","unstructured":"Fleischmajer R, Damiano V, Nedwich A. Alteration of subcutaneous tissue in systemic scleroderma. Arch Dermatol. 1972;105(1):59\u201366.","journal-title":"Arch Dermatol"},{"issue":"5","key":"627_CR22","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1590\/S0100-879X1998000500009","volume":"31","author":"ZDA Andrade","year":"1998","unstructured":"Andrade ZDA, de-Oliveira-Filho J, Fernandes AL. Interrelationship between adipocytes and fibroblasts during acute damage to the subcutaneous adipose tissue of rats: an ultrastructural study. Braz J Med Biol Res. 1998;31(5):659\u201364.","journal-title":"Braz J Med Biol Res"},{"issue":"1","key":"627_CR23","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/jcp.21304","volume":"215","author":"M Matsumoto","year":"2008","unstructured":"\u2022 Matsumoto M et al. Mature adipocyte\u2010derived dedifferentiated fat cells exhibit multilineage potential. J Cell Physiol. 2008;215(1):210\u201322. Mature adipocytes can dedifferentiate in fibroblast-like cells producing highly phenotypically homogeneous cell population.","journal-title":"J Cell Physiol"},{"issue":"2","key":"627_CR24","doi-asserted-by":"crossref","first-page":"519","DOI":"10.2353\/ajpath.2009.080574","volume":"174","author":"M Wu","year":"2009","unstructured":"Wu M et al. Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-\u03b3. Am J Pathol. 2009;174(2):519\u201333.","journal-title":"Am J Pathol"},{"issue":"1","key":"627_CR25","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2174\/1874312901206010103","volume":"6","author":"J Wei","year":"2012","unstructured":"Wei J et al. Regulation of matrix remodeling by peroxisome proliferator-activated receptor-\u03b3: a novel link between metabolism and fibrogenesis. Open Rheumatol J. 2012;6(1):103\u201315.","journal-title":"Open Rheumatol J"},{"issue":"11","key":"627_CR26","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1111\/exd.12256","volume":"22","author":"S Ohgo","year":"2013","unstructured":"Ohgo S et al. Bleomycin inhibits adipogenesis and accelerates fibrosis in the subcutaneous adipose layer through TGF\u2010\u03b21. Exper Dermatol. 2013;22(11):769\u201371.","journal-title":"Exper Dermatol"},{"issue":"1","key":"627_CR27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tem.2015.11.002","volume":"27","author":"IL Kruglikov","year":"2016","unstructured":"\u2022 Kruglikov IL, Scherer PE. Dermal adipocytes: from irrelevance to metabolic targets? Trend Endocrinol Metab. 2016;27(1):1\u201310. Interfacial fat tissue in dermis is presented by dermal adipocytes which are involved in different physiological and pathological processes.","journal-title":"Trend Endocrinol Metab"},{"issue":"4","key":"627_CR28","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1046\/j.1524-475X.2001.00269.x","volume":"9","author":"H Matsumura","year":"2001","unstructured":"Matsumura H et al. Cones of skin occur where hypertrophic scar occurs. Wound Rep Regen. 2001;9(4):269\u201377.","journal-title":"Wound Rep Regen"},{"issue":"4","key":"627_CR29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019024","volume":"6","author":"LH Engrav","year":"2011","unstructured":"Engrav LH et al. Functional genomics unique to week 20 post wounding in the deep cone\/fat dome of the Duroc\/Yorkshire porcine model of fibroproliferative scarring. PLoS One. 2011;6(4), e19024.","journal-title":"PLoS One"},{"key":"627_CR30","doi-asserted-by":"crossref","first-page":"2.1","DOI":"10.1146\/annurev-cellbio-111315-125426","volume":"32","author":"B Shook","year":"2016","unstructured":"Shook B et al. The role of adipocytes in tissue regeneration and stem cell niches. Ann Rev Cell Develop Biol. 2016;32:2.1\u20132.32.","journal-title":"Ann Rev Cell Develop Biol"},{"issue":"3","key":"627_CR31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0059811","volume":"8","author":"K Wojciechowicz","year":"2013","unstructured":"Wojciechowicz K et al. Development of the mouse dermal adipose layer occurs independently of subcutaneous adipose tissue and is marked by restricted early expression of FABP4. PLoS One. 2013;8(3), e59811.","journal-title":"PLoS One"},{"issue":"9","key":"627_CR32","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/exd.12450","volume":"23","author":"RR Driskell","year":"2014","unstructured":"Driskell RR et al. Defining dermal adipose tissue. Exp Dermatol. 2014;23(9):629\u201331.","journal-title":"Exp Dermatol"},{"issue":"5","key":"627_CR33","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.cell.2011.07.019","volume":"146","author":"E Festa","year":"2011","unstructured":"Festa E et al. Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling. Cell. 2011;146(5):761\u201371.","journal-title":"Cell"},{"issue":"7196","key":"627_CR34","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/nature06902","volume":"453","author":"KL Spalding","year":"2008","unstructured":"Spalding KL et al. Dynamics of fat cell turnover in humans. Nature. 2008;453(7196):783\u20137.","journal-title":"Nature"},{"issue":"10","key":"627_CR35","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1002\/stem.1756","volume":"32","author":"A Prokesch","year":"2014","unstructured":"Prokesch A et al. Molecular aspects of adipoepithelial transdifferentiation in mouse mammary gland. Stem Cells. 2014;32(10):2756\u201366.","journal-title":"Stem Cells"},{"issue":"4","key":"627_CR36","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/exd.12941","volume":"25","author":"IL Kruglikov","year":"2016","unstructured":"Kruglikov IL, Scherer PE. Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot? Exper Dermatol. 2016;25(4):258\u201362.","journal-title":"Exper Dermatol"},{"issue":"4","key":"627_CR37","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.devcel.2012.08.017","volume":"23","author":"J Davis","year":"2012","unstructured":"Davis J. A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev Cell. 2012;23(4):705\u201315.","journal-title":"Dev Cell"},{"issue":"3","key":"627_CR38","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/MNH.0b013e328344c3d4","volume":"20","author":"C Schrimpf","year":"2011","unstructured":"Schrimpf C, Duffield JS. Mechanisms of fibrosis: the role of the pericyte. Curr Opin Nephrol Hypertens. 2011;20(3):297\u2013305.","journal-title":"Curr Opin Nephrol Hypertens"},{"issue":"2","key":"627_CR39","doi-asserted-by":"crossref","first-page":"a011908","DOI":"10.1101\/cshperspect.a011908","volume":"4","author":"P Nistic\u00f2","year":"2012","unstructured":"Nistic\u00f2 P, Bissell MJ, Radisky DC. Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases. Cold Spring Harb Perspect Biol. 2012;4(2):a011908.","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"4","key":"627_CR40","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3390\/jcm5040045","volume":"5","author":"S Piera-Velazquez","year":"2016","unstructured":"Piera-Velazquez S, Mendoza FA, Jimenez SA. Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of human fibrotic diseases. J Clin Med. 2016;5(4):45.","journal-title":"J Clin Med"},{"issue":"5","key":"627_CR41","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1165\/rcmb.2012-0262OC","volume":"48","author":"G Garrison","year":"2013","unstructured":"Garrison G et al. Reversal of myofibroblast differentiation by prostaglandin e2. Am J Respir Cell Mol Biol. 2013;48(5):550\u20138.","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"3","key":"627_CR42","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/nrm3758","volume":"15","author":"S Lamouille","year":"2014","unstructured":"Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial\u2013mesenchymal transition. Nat Rev Mol Cell Biol. 2014;15(3):178\u201396.","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"7524","key":"627_CR43","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nature13839","volume":"514","author":"E Ubil","year":"2014","unstructured":"Ubil E et al. Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature. 2014;514(7524):585\u201390.","journal-title":"Nature"},{"issue":"10","key":"627_CR44","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1016\/j.ajpath.2015.06.005","volume":"185","author":"V Martins","year":"2015","unstructured":"Martins V et al. FIZZ1-induced myofibroblast transdifferentiation from adipocytes and its potential role in dermal fibrosis and lipoatrophy. Am J Pathol. 2015;185(10):2768\u201376.","journal-title":"Am J Pathol"},{"issue":"Suppl. 1","key":"627_CR45","doi-asserted-by":"crossref","first-page":"927.10","DOI":"10.1096\/fasebj.29.1_supplement.927.10","volume":"29","author":"T Liu","year":"2015","unstructured":"Liu T et al. A role for FIZZ1 in a model of scleroderma. FASEB J. 2015;29 Suppl 1:927.10.","journal-title":"FASEB J"},{"issue":"2","key":"627_CR46","volume":"9","author":"T Liu","year":"2014","unstructured":"Liu T et al. The in vivo fibrotic role of FIZZ1 in pulmonary fibrosis. PLoS One. 2014;9(2), e88362.","journal-title":"PLoS One"},{"issue":"2","key":"627_CR47","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1186\/ar2598","volume":"11","author":"C Beyer","year":"2009","unstructured":"Beyer C et al. Hypoxia in the pathogenesis of systemic sclerosis. Arthritis Res Ther. 2009;11(2):220.","journal-title":"Arthritis Res Ther"},{"issue":"1","key":"627_CR48","volume":"9","author":"VD Desai","year":"2014","unstructured":"\u2022 Desai VD, Hsia HC, Schwarzbauer JE. Reversible modulation of myofibroblast differentiation in adipose-derived mesenchymal stem cells. PLoS One. 2014;9(1), e86865. Myofibroblasts can differentiate in adipogenic cells in vitro.","journal-title":"PLoS One"},{"issue":"5","key":"627_CR49","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1002\/path.4481","volume":"235","author":"E Hamburg\u2010Shields","year":"2015","unstructured":"Hamburg\u2010Shields E et al. Sustained \u03b2\u2010catenin activity in dermal fibroblasts promotes fibrosis by up\u2010regulating expression of extracellular matrix protein\u2010coding genes. J Pathol. 2015;235(5):686\u201397.","journal-title":"J Pathol"},{"issue":"6","key":"627_CR50","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.jid.2016.01.036","volume":"136","author":"M Mastrogiannaki","year":"2016","unstructured":"\u2022 Mastrogiannaki M et al. \u03b2-Catenin stabilization in skin fibroblasts causes fibrotic lesions by preventing adipocyte differentiation of the reticular dermis. J Invest Dermatol. 2016;136(6):1130\u201342. Beta-catenin stabilization of fibroblasts leads to reduction of dermal adipose tissue and induction of dermal fibrosis.","journal-title":"J Invest Dermatol"},{"key":"627_CR51","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1242\/dev.131797","volume":"143","author":"E Rognoni","year":"2016","unstructured":"Rognoni E et al. Inhibition of \u03b2-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing. Develop. 2016;143:2522\u201335.","journal-title":"Develop"},{"issue":"6","key":"627_CR52","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1002\/art.30312","volume":"63","author":"J Wei","year":"2011","unstructured":"Wei J et al. Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum. 2011;63(6):1707\u201317.","journal-title":"Arthritis Rheum"},{"issue":"1","key":"627_CR53","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1620\/tjem.223.45","volume":"223","author":"TH Kim","year":"2011","unstructured":"Kim TH et al. Blockade of the Wnt\/\u03b2-Catenin pathway attenuates bleomycin-induced pulmonary fibrosis. Tohoku J Exper Med. 2011;223(1):45\u201354.","journal-title":"Tohoku J Exper Med"},{"issue":"1","key":"627_CR54","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jdermsci.2011.09.012","volume":"65","author":"J Liu","year":"2012","unstructured":"Liu J et al. Wnt\/\u03b2-catenin pathway forms a negative feedback loop during TGF-\u03b21 induced human normal skin fibroblast-to-myofibroblast transition. J Dermatol Sci. 2012;65(1):38\u201349.","journal-title":"J Dermatol Sci"},{"issue":"1","key":"627_CR55","first-page":"7","volume":"51","author":"M Oi","year":"2004","unstructured":"Oi M, Yamamoto T, Nishioka K. Increased expression of TGF-b1 in the sclerotic skin in bleomycin-\u2018susceptible\u2019 mouse strains. J Med Dent Sci. 2004;51(1):7\u201317.","journal-title":"J Med Dent Sci"},{"issue":"1","key":"627_CR56","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s13075-015-0659-5","volume":"17","author":"N Ruzehaji","year":"2015","unstructured":"Ruzehaji N et al. Combined effect of genetic background and gender in a mouse model of bleomycin-induced skin fibrosis. Arthritis Res Ther. 2015;17(1):145.","journal-title":"Arthritis Res Ther"},{"key":"627_CR57","doi-asserted-by":"crossref","first-page":"67439","DOI":"10.1371\/journal.pone.0067439","volume":"8","author":"Y Wang","year":"2013","unstructured":"Wang Y et al. Hyperelastic material properties of mouse skin under compression. PLoS One. 2013;8:67439.","journal-title":"PLoS One"},{"issue":"1","key":"627_CR58","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.0022-202X.2004.23545.x","volume":"124","author":"L Azzi","year":"2005","unstructured":"Azzi L et al. Gender differences in mouse skin morphology and specific effects of sex steroids and dehydroepiandrosterone. J Invest Dermatol. 2005;124(1):22\u20137.","journal-title":"J Invest Dermatol"},{"key":"627_CR59","first-page":"27","volume":"2","author":"CM Chao","year":"2014","unstructured":"Chao CM et al. A breath of fresh air on the mesenchyme: impact of impaired mesenchymal development on the pathogenesis of bronchopulmonary dysplasia. Front Med. 2014;2:27.","journal-title":"Front Med"},{"issue":"8","key":"627_CR60","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1080\/01902140600880257","volume":"32","author":"VK Rehan","year":"2006","unstructured":"Rehan VK et al. Evidence for the presence of lipofibroblasts in human lung. Exp Lung Res. 2006;32(8):379\u201393.","journal-title":"Exp Lung Res"},{"issue":"5","key":"627_CR61","doi-asserted-by":"crossref","first-page":"L386","DOI":"10.1152\/ajplung.00131.2014","volume":"307","author":"D Tahedl","year":"2014","unstructured":"Tahedl D et al. How common is the lipid body-containing interstitial cell in the mammalian lung? Am J Physiol Lung Cell Mol Physiol. 2014;307(5):L386\u201394.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"8","key":"627_CR62","doi-asserted-by":"crossref","first-page":"L605","DOI":"10.1152\/ajplung.00230.2014","volume":"307","author":"K Ahlbrecht","year":"2014","unstructured":"Ahlbrecht K, McGowan SE. In search of the elusive lipofibroblast in human lungs. Am J Physiol Lung Cell Mol Physiol. 2014;307(8):L605\u20138.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"8","key":"627_CR63","doi-asserted-by":"crossref","first-page":"L618","DOI":"10.1152\/ajplung.00144.2014","volume":"307","author":"SE McGowan","year":"2014","unstructured":"McGowan SE, McCoy DM. Regulation of fibroblast lipid storage and myofibroblast phenotypes during alveolar septation in mice. Am J Physiol Lung Cell Mol Physiol. 2014;307(8):L618\u201331.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"4","key":"627_CR64","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1165\/rcmb.2012-0030OC","volume":"47","author":"L Chen","year":"2012","unstructured":"Chen L et al. Dynamic regulation of platelet-derived growth factor receptor alpha expression in alveolar fibroblasts during realveolarization. Am J Respir Cell Mol Biol. 2012;47(4):517\u201327.","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"13","key":"627_CR65","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1089\/ars.2013.5793","volume":"21","author":"VK Rehan","year":"2014","unstructured":"Rehan VK, Torday JS. The lung alveolar lipofibroblast: an evolutionary strategy against neonatal hyperoxic lung injury. Antioxid Redox Signal. 2014;21(13):1893\u2013904.","journal-title":"Antioxid Redox Signal"},{"key":"627_CR66","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s13058-016-0740-2","volume":"18","author":"K Bussard","year":"2016","unstructured":"Bussard K et al. Tumor-associated stromal cells as key contributors to the tumor microenvironment. Breast Cancer Res. 2016;18:84.","journal-title":"Breast Cancer Res"},{"issue":"18","key":"627_CR67","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1158\/0008-5472.CAN-13-0530","volume":"73","author":"L Bochet","year":"2013","unstructured":"\u2022 Bochet L et al. Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer. Cancer Res. 2013;73(18):5657\u201368. Pretumoral mature adipocytes can dedifferentiate producing cell with mixed adipocyte-fibroblast markers.","journal-title":"Cancer Res"},{"issue":"12","key":"627_CR68","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.4161\/cbt.5.12.3354","volume":"5","author":"H Sugimoto","year":"2006","unstructured":"Sugimoto H et al. Identification of fibroblast heterogeneity in the tumor microenvironment. Cancer Biol Ther. 2006;5(12):1640\u20136.","journal-title":"Cancer Biol Ther"},{"issue":"5","key":"627_CR69","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.bbalip.2013.02.005","volume":"1831","author":"A Frontini","year":"2013","unstructured":"Frontini A et al. White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma. Biochim Biophys Acta. 2013;1831(5):950\u20139.","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"627_CR70","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1471-2407-14-126","volume":"14","author":"Q Cao","year":"2014","unstructured":"Cao Q et al. A pilot study of FDG PET\/CT detects a link between brown adipose tissue and breast cancer. BMC Cancer. 2014;14(1):126.","journal-title":"BMC Cancer"},{"issue":"2","key":"627_CR71","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/cdd.2014.148","volume":"22","author":"AC Daquinag","year":"2015","unstructured":"\u2022 Daquinag AC et al. Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development. Cell Death Differ. 2015;22(2):351\u201363. Depletion of white adipocyte progenitors can induce the transdifferentiation of white-to-beige adipocytes.","journal-title":"Cell Death Differ"},{"issue":"2","key":"627_CR72","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.cmet.2015.06.022","volume":"22","author":"LS Sidossis","year":"2015","unstructured":"Sidossis LS et al. Browning of subcutaneous white adipose tissue in humans after severe adrenergic stress. Cell Metab. 2015;22(2):219\u201327.","journal-title":"Cell Metab"},{"issue":"2","key":"627_CR73","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1155\/2010\/695162","volume":"33","author":"C Jotzu","year":"2010","unstructured":"Jotzu C et al. Adipose tissue-derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor-derived factors. Anal Cell Pathol. 2010;33(2):61\u201379.","journal-title":"Anal Cell Pathol"},{"issue":"1","key":"627_CR74","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13058-016-0688-2","volume":"18","author":"A Weigand","year":"2016","unstructured":"Weigand A et al. Selective isolation and characterization of primary cells from normal breast and tumors reveal plasticity of adipose derived stem cells. Breast Cancer Res. 2016;18(1):32.","journal-title":"Breast Cancer Res"},{"issue":"4","key":"627_CR75","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.3390\/cancers7040902","volume":"7","author":"K Shiga","year":"2015","unstructured":"Shiga K et al. Cancer-associated fibroblasts: their characteristics and their roles in tumor growth. Cancers. 2015;7(4):2443\u201358.","journal-title":"Cancers"},{"issue":"301","key":"627_CR76","doi-asserted-by":"crossref","first-page":"301ra130","DOI":"10.1126\/scitranslmed.3010467","volume":"7","author":"BR Seo","year":"2015","unstructured":"Seo BR et al. Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis. Sci Transl Med. 2015;7(301):301ra130.","journal-title":"Sci Transl Med"},{"issue":"5","key":"627_CR77","volume":"5","author":"TH Kim","year":"2016","unstructured":"Kim TH, Rowat AC, Sloan EK. Neural regulation of cancer: from mechanobiology to inflammation. Clin Translat Immunol. 2016;5(5), e78.","journal-title":"Clin Translat Immunol"},{"issue":"1","key":"627_CR78","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/mt.2015.155","volume":"24","author":"AC Daquinag","year":"2016","unstructured":"Daquinag AC et al. Targeted proapoptotic peptides depleting adipose stromal cells inhibit tumor growth. Mol Ther. 2016;24(1):34\u201340.","journal-title":"Mol Ther"},{"issue":"2","key":"627_CR79","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1158\/0008-5472.CAN-15-0927","volume":"76","author":"M Picon-Ruiz","year":"2016","unstructured":"Picon-Ruiz M et al. Interactions between adipocytes and breast cancer cells stimulate cytokine production and drive Src\/Sox2\/miR-302b\u2013mediated malignant progression. Cancer Res. 2016;76(2):491\u2013504.","journal-title":"Cancer Res"},{"issue":"7","key":"627_CR80","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1158\/1541-7786.MCR-16-0055","volume":"14","author":"M Anjanappa","year":"2016","unstructured":"Anjanappa M et al. Distinct effects of adipose-derived stem cells and adipocytes on normal and cancer cell hierarchy. Mol Cancer Res. 2016;14(7):660\u201371.","journal-title":"Mol Cancer Res"},{"issue":"1","key":"627_CR81","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12931-015-0202-x","volume":"16","author":"E Langhe De","year":"2015","unstructured":"De Langhe E et al. Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis. Respir Res. 2015;16(1):38.","journal-title":"Respir Res"},{"issue":"9","key":"627_CR82","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.2337\/db13-0473","volume":"62","author":"B Gustafson","year":"2013","unstructured":"Gustafson B et al. Restricted adipogenesis in hypertrophic obesity: the role of WISP2, WNT, and BMP4. Diabetes. 2013;62(9):2997\u20133004.","journal-title":"Diabetes"},{"issue":"5","key":"627_CR83","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.2337\/db14-1127","volume":"64","author":"B Gustafson","year":"2015","unstructured":"Gustafson B et al. BMP4 and BMP antagonists regulate human white and beige adipogenesis. Diabetes. 2015;64(5):1670\u201381.","journal-title":"Diabetes"},{"issue":"2","key":"627_CR84","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.tcb.2014.10.001","volume":"25","author":"RR Driskell","year":"2015","unstructured":"Driskell RR, Watt FM. Understanding fibroblast heterogeneity in the skin. Trend Cell Biol. 2015;25(2):92\u20139.","journal-title":"Trend Cell Biol"},{"issue":"12","key":"627_CR85","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1038\/labinvest.2008.101","volume":"88","author":"JF Wang","year":"2008","unstructured":"Wang JF et al. Deep dermal fibroblasts contribute to hypertrophic scarring. Lab Invest. 2008;88(12):1278\u201390.","journal-title":"Lab Invest"},{"issue":"1","key":"627_CR86","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/exd.12069","volume":"22","author":"D Janson","year":"2013","unstructured":"Janson D et al. Papillary fibroblasts differentiate into reticular fibroblasts after prolonged in vitro culture. Exper Dermatol. 2013;22(1):48\u201353.","journal-title":"Exper Dermatol"},{"key":"627_CR87","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2016.08.010","author":"S Joost","year":"2016","unstructured":"Joost S et al. Single-cell transcriptomics reveals that differentiation and spatial signatures shape epidermal and hair follicle heterogeneity. Cell Syst. 2016. doi: 10.1016\/j.cels.2016.08.010 .","journal-title":"Cell Syst"}],"container-title":["Current Rheumatology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11926-017-0627-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11926-017-0627-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11926-017-0627-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T00:14:57Z","timestamp":1719015297000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11926-017-0627-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":87,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["627"],"URL":"https:\/\/doi.org\/10.1007\/s11926-017-0627-y","relation":{},"ISSN":["1523-3774","1534-6307"],"issn-type":[{"value":"1523-3774","type":"print"},{"value":"1534-6307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"article-number":"4"}}