{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:18:19Z","timestamp":1761675499443},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Urol Rep"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1007\/s11934-005-0037-y","type":"journal-article","created":{"date-parts":[[2007,6,5]],"date-time":"2007-06-05T18:53:34Z","timestamp":1181069614000},"page":"429-433","source":"Crossref","is-referenced-by-count":14,"title":["Intravesical Therapy for Overactive Bladder"],"prefix":"10.1007","volume":"6","author":[{"given":"Robert J.","family":"Evans","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"issue":"suppl 5A","key":"37_CR1","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0090-4295(99)00492-6","volume":"55","author":"CR Chapple","year":"2000","unstructured":"Chapple CR: Muscarinic antagonists in the treatment of overactive bladder. Urology 2000, 55(suppl 5A):33\u201346.","journal-title":"Urology"},{"issue":"suppl 5A","key":"37_CR2","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/S0090-4295(99)00498-7","volume":"55","author":"CJ Fowler","year":"2000","unstructured":"Fowler CJ: Intravesical treatment of overactive bladder. Urology 2000, 55(suppl 5A):60\u201364. This concise, easily readable review describes the scientific basis behind intravesical treatment of lower urinary tract dysfunction and is written by one of the founders in the field of neurourology.","journal-title":"Urology"},{"key":"37_CR3","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1016\/S0022-5347(05)64261-9","volume":"168","author":"N Yoshimura","year":"2002","unstructured":"Yoshimura N, Chancellor MB: Current and future pharmacological treatment of overactive bladder. J Urol 2002, 168:1897\u20131913. A comprehensive review of the literature that not only summarizes currently available treatment options, but provides a look at potential future treatment modalities.","journal-title":"J Urol"},{"key":"37_CR4","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/S0022-5347(17)41304-8","volume":"141","author":"CB Brendler","year":"1989","unstructured":"Brendler CB, Radebaugh LC, Mohler JL: Topical oxybutynin chloride for relaxation of dysfunctional bladders. J Urol 1989, 141:1350\u20131352.","journal-title":"J Urol"},{"key":"37_CR5","first-page":"84","volume":"29","author":"H Madersbacher","year":"1991","unstructured":"Madersbacher H, Jilg G: Control of detrusor hyperreflexia by the intravesical solution of oxybutynin hydrochloride. Paraplegia 1991, 29:84\u201390.","journal-title":"Paraplegia"},{"key":"37_CR6","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0022-5347(17)36663-6","volume":"148","author":"CA Massad","year":"1992","unstructured":"Massad CA, Kogan BA, Trigo-Rocha FE: The pharmacokinetics of intravesical and oral oxybutynin chloride. J Urol 1992, 148:595\u2013597.","journal-title":"J Urol"},{"key":"37_CR7","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1080\/003655902317259319","volume":"36","author":"K Lehtoranta","year":"2002","unstructured":"Lehtoranta K, Tainio H, Lukkari-Lax E, et al.: Pharmacokinetics efficacy and safety of intravesical formulation of oxybutynin in patients with detrusor overactivity. Scand J Urol Nephrol 2002, 36:18\u201324.","journal-title":"Scand J Urol Nephrol"},{"key":"37_CR8","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/S0022-5347(01)62828-3","volume":"160","author":"G Buyse","year":"1998","unstructured":"Buyse G, Waldeck K, Verpoorten C, et al.: Intravesical oxybutynin for neurogenic bladder dysfunction: less systemic side effects due to reduced first pass metabolism. J Urol 1998, 160:892\u2013896.","journal-title":"J Urol"},{"key":"37_CR9","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0022-5347(17)37845-X","volume":"146","author":"SP Greenfield","year":"1991","unstructured":"Greenfield SP, Fera M: The use of intravesical oxybutynin chloride in children with neurogenic bladder. J Urol 1991, 146:532\u2013534.","journal-title":"J Urol"},{"key":"37_CR10","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/0090-4295(93)90098-U","volume":"41","author":"DL Weese","year":"1993","unstructured":"Weese DL, Roskamp DA, Leach GE, et al.: Intravesical oxybutynin chloride: experience with forty-two patients. Urology 1993, 41:527\u2013530.","journal-title":"Urology"},{"key":"37_CR11","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/S0022-5347(17)35130-3","volume":"151","author":"NG Kasabian","year":"1994","unstructured":"Kasabian NG, Vlachiotis JD, Lais A, et al.: The use of intravesical oxybutynin chloride in patients with detrusor hypertonicity and detrusor hyper-reflexia. J Urol 1994, 151:944\u2013945.","journal-title":"J Urol"},{"key":"37_CR12","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1016\/S0022-5347(01)65629-5","volume":"156","author":"KA Painter","year":"1996","unstructured":"Painter KA, Vates TS, Bukowski TP, et al.: Long-term intravesical oxybutynin chloride therapy in children with myelodysplasia. J Urol 1996, 156:1459\u20131462.","journal-title":"J Urol"},{"key":"37_CR13","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1016\/S0022-5347(01)65238-8","volume":"157","author":"LS Palmer","year":"1997","unstructured":"Palmer LS, Zebold K, Firlit CF, et al.: Complications of intravesical oxybutynin chloride therapy in the pediatric myelomeningocele population. J Urol 1997, 157:638\u2013640.","journal-title":"J Urol"},{"key":"37_CR14","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1038\/sj.sc.3100995","volume":"38","author":"PA Haferkamp","year":"2000","unstructured":"Haferkamp PA, Stachler J, Gerner HJ, et al.: Dosage escalation of intravesical oxybutynin in the treatment of neurogenic bladder patients. Spinal Cord 2000, 38:250\u2013254.","journal-title":"Spinal Cord"},{"key":"37_CR15","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1464-410X.1993.tb16210.x","volume":"72","author":"KJ O\u2019Flynn","year":"1993","unstructured":"O\u2019Flynn KJ, Thomas DG: Intravesical instillation of oxybutynin hydrochloride for detrusor hyperreflexia. Br J Urol 1993, 72:566\u2013570.","journal-title":"Br J Urol"},{"key":"37_CR16","doi-asserted-by":"publisher","first-page":"1892","DOI":"10.1097\/01.ju.0000049903.60057.4b","volume":"169","author":"S DeWachter","year":"2003","unstructured":"DeWachter S, Wyndaele JJ: Intravesical oxybutynin: a local anesthetic effect on bladder c afferents. J Urol 2003, 169:1892\u20131895.","journal-title":"J Urol"},{"key":"37_CR17","doi-asserted-by":"publisher","first-page":"I358","DOI":"10.1016\/S0090-4295(99)00540-3","volume":"55","author":"J Pannek","year":"2000","unstructured":"Pannek J, Sommerfeld HJ, Botel U, et al.: Combined intravesical and oral oxybutynin chloride in adult patients with spinal cord injury. Urology 2000, 55:I358-I362.","journal-title":"Urology"},{"key":"37_CR18","first-page":"36","volume":"33","author":"S Glickman","year":"1995","unstructured":"Glickman S, Tsokkos N, Shah PJ: Intravesical atropine and suppression of detrusor hypercontractility in the neuropathic bladder: a preliminary study. Paraplegia 1995, 33:36\u201339.","journal-title":"Paraplegia"},{"key":"37_CR19","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1136\/jnnp.65.6.957","volume":"65","author":"C Deaney","year":"1998","unstructured":"Deaney C, Glickman S, Gluck T, et al.: Intravesical atropine suppression of detrusor hyperreflexia in multiple sclerosis. J Neurol Neurosurg Psychiatry 1998, 65:957\u2013958.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"37_CR20","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1046\/j.1464-410x.2001.02134.x","volume":"81","author":"R Enskat","year":"2001","unstructured":"Enskat R, Deaney CN, Glickman S: Systemic effects of intravesical atropine sulfate. BJU Int 2001, 81:613\u2013616.","journal-title":"BJU Int"},{"key":"37_CR21","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1016\/S0022-5347(05)67283-7","volume":"164","author":"B Schurch","year":"2000","unstructured":"Schurch B, St\u00f6hrer M, Kramer G, et al.: Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: a new alternative to anticholinergic drugs? Preliminary results. J Urol 2000, 164:692\u2013697.","journal-title":"J Urol"},{"key":"37_CR22","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1056\/NEJM200003023420918","volume":"342","author":"B Schurch","year":"2000","unstructured":"Schurch B, Schmid DM, St\u00f6hrer M: Treatment of neurogenic incontinence with botulinum toxin A. N Engl J Med 2000, 342:665.","journal-title":"N Engl J Med"},{"key":"37_CR23","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/S0090-4295(01)01641-7","volume":"59","author":"H Schulk-Baukloh","year":"2002","unstructured":"Schulk-Baukloh H, Michael T, Schobert T, et al.: Efficacy of botulinum toxin in children with detrusor hyperreflexia due to myelomeningocele: preliminary results. Urology 2002, 59:325\u2013327.","journal-title":"Urology"},{"key":"37_CR24","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1038\/sj.sc.3101584","volume":"42","author":"A Reitz","year":"2004","unstructured":"Reitz A, Schurch B: Intravesical therapy option for neurogenic detrusor overactivity. Spinal Cord 2004, 42:267\u2013272.","journal-title":"Spinal Cord"},{"key":"37_CR25","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/S0022-5347(05)67355-7","volume":"164","author":"O Yokoyama","year":"2000","unstructured":"Yokoyama O, Kimatu K, Kodama K, et al.: Diagnostic value of intravesical lidocaine for overactive bladder. J Urol 2000, 164:340\u2013343.","journal-title":"J Urol"},{"key":"37_CR26","doi-asserted-by":"publisher","first-page":"2380","DOI":"10.1016\/S0022-5347(05)66209-X","volume":"165","author":"SP Lapointe","year":"2001","unstructured":"Lapointe SP, Wang B, Kennedy WA, et al.: The effects of intravesical lidocaine on bladder dynamics of children with myelomeningocele. J Urol 2001, 165:2380\u20132382.","journal-title":"J Urol"},{"key":"37_CR27","first-page":"127","volume":"30","author":"PD McInemey","year":"1992","unstructured":"McInemey PD, Grant A, Chawla J, et al.: The effect of intravesical Marcaine instillation on hyperreflexic detrusor contractions. Paraplegia 1992, 30:127\u2013130.","journal-title":"Paraplegia"},{"key":"37_CR28","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1016\/S0022-5347(01)64870-5","volume":"159","author":"O Yokoyama","year":"1997","unstructured":"Yokoyama O, Ishura T, Nakamura T, et al.: Urodynamic effects of intravesical instillation of lidocaine in patients with overactive detrusor. J Urol 1997, 159:1826\u20131830.","journal-title":"J Urol"},{"key":"37_CR29","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/00005392-199907000-00002","volume":"162","author":"MB Chancellor","year":"1999","unstructured":"Chancellor MB, deGroat WC: Intravesical capsaicin and resiniferatoxin therapy: spicing up ways that we treat the overactive bladder. J Urol 1999, 162:3\u201311.","journal-title":"J Urol"},{"key":"37_CR30","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1038\/39807","volume":"389","author":"MJ Caterina","year":"1997","unstructured":"Caterina MJ, Schumacher MA, Tominaga M, et al.: The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997, 389:816\u2013824.","journal-title":"Nature"},{"key":"37_CR31","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1016\/0140-6736(92)91186-C","volume":"339","author":"CJ Fowler","year":"1992","unstructured":"Fowler CJ, Jewkes D, McDonald WI, et al.: Intravesical capsaicin for neurogenic bladder dysfunction. Lancet 1992, 339:1239.","journal-title":"Lancet"},{"key":"37_CR32","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1038\/sj.sc.3100505","volume":"36","author":"L Wiart","year":"1998","unstructured":"Wiart L, Joseph P, Petit H, et al.: The effects of capsaicin on the neurogenic hyperreflexic detrusor: a double-blind, placebo-controlled study in patients with spinal cord disease. Preliminary results. Spinal Cord 1998, 36:95\u201399.","journal-title":"Spinal Cord"},{"key":"37_CR33","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1002\/(SICI)1520-6777(1998)17:5<513::AID-NAU7>3.0.CO;2-G","volume":"17","author":"M de Seze","year":"1998","unstructured":"deSeze M, Wiart L, Joseph P, et al.: Capsaicin and neurogenic detrusor hyperreflexia: a double-blind, placebo-controlled study in twenty patients with spinal cord lesions. Neurourol Urodyn 1998, 17:513\u2013523.","journal-title":"Neurourol Urodyn"},{"key":"37_CR34","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1159\/000020004","volume":"36","author":"M de Seze","year":"1999","unstructured":"de SezeM, Wiart L, Ferriere J, et al.: Intravesical instillation of capsaicin in urology: a review of the literature. Eur Urol 1999, 36:267\u2013277.","journal-title":"Eur Urol"},{"key":"37_CR35","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1016\/S0022-5347(01)68162-X","volume":"158","author":"D DeRidder","year":"1997","unstructured":"DeRidder D, Chandiramani V, Dasgupta P, et al.: Intravesical capsaicin as a treatment for refractory detrusor hyperreflexia: a duel center study with long-term follow-up. J Urol 1997, 158:2087\u20132092.","journal-title":"J Urol"},{"key":"37_CR36","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/S0022-5347(01)63985-5","volume":"159","author":"A Avelino","year":"1998","unstructured":"Avelino A, Cruz F, Colimbra A: Lidocaine prevents noxious excitation of bladder afferents induced by intravesical capsaicin without interfering with the ensuing sensory desensitization: an experimental study in the rat. J Urol 1998, 159:567\u2013570.","journal-title":"J Urol"},{"key":"37_CR37","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/S0022-5347(01)65211-X","volume":"157","author":"F Cruz","year":"1997","unstructured":"Cruz F, Guimares M, Silva C, et al.: Desensitization of bladder sensory fibers by intravesical capsaicin has long-lasting clinical and urodynamic effects in patients with hyperactive or hypersensitive bladder dysfunction. J Urol 1997, 157:585\u2013589.","journal-title":"J Urol"},{"key":"37_CR38","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/S0140-6736(05)63330-2","volume":"350","author":"F Cruz","year":"1993","unstructured":"Cruz F, Guimares M, Silva C, et al.: Suppression of bladder hyperreflexia by intravesical resiniferatoxin. Lancet 1993, 350:640\u2013641.","journal-title":"Lancet"},{"key":"37_CR39","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1080\/003655998750015287","volume":"32","author":"M Lazzeri","year":"1998","unstructured":"Lazzeri M, Spinelli M, Beneforti P, et al.: Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord disease. Scand J Urol Nephrol 1998, 32:331\u2013334.","journal-title":"Scand J Urol Nephrol"},{"key":"37_CR40","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1159\/000020322","volume":"38","author":"C Silva","year":"2000","unstructured":"Silva C, Rio ME, Cruz F: Desensitization of bladder sensory fibers by intravesical resiniferatoxin, a capsaicin analog: long-term results for the treatment of detrusor hyperreflexia. Eur Urol 2000, 38:444\u2013452.","journal-title":"Eur Urol"},{"key":"37_CR41","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1097\/01.ju.0000100385.93801.d4","volume":"171","author":"M DeSeze","year":"2004","unstructured":"DeSeze M, Wairt L, deSeze MP, et al.: Intravesical capsaicin vs resiniferatoxin for the treatment of detrusor hyperreflexia in spinal cord injured patients: a double-blind, randomized, controlled study. J Urol 2004, 171:251\u2013255.","journal-title":"J Urol"},{"key":"37_CR42","first-page":"333","volume":"32","author":"M Lazzeri","year":"1998","unstructured":"Lazzeri M, Spinelli M, Beneforti P, et al.: Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord disease. Scand J Urol Nephrol 1998, 32:333\u2013334.","journal-title":"Scand J Urol Nephrol"},{"key":"37_CR43","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1016\/S0022-5347(05)65183-X","volume":"167","author":"A Giannantoni","year":"2002","unstructured":"Giannantoni A, DiStasi SM, Steven RL, et al.: Intravesical capsaicin vs resiniferatoxin in patients with detrusor hyperreflexia: a perspective, randomized study. J Urol 2002, 167:1710\u20131714.","journal-title":"J Urol"},{"key":"37_CR44","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/S0022-5347(05)67279-5","volume":"164","author":"M Lazzeri","year":"2000","unstructured":"Lazzeri M, Spinelli M, Beneforti P: Intravesical resiniferatoxin for the treatment of hypersensitive disorder: a randomized, placebo-controlled study. J Urol 2000, 164:676\u2013679.","journal-title":"J Urol"},{"key":"37_CR45","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/S0022-5347(01)65669-6","volume":"156","author":"M Lazzeri","year":"1996","unstructured":"Lazzeri M, Beneforti P, Benaim G: Intravesical capsaicin for the treatment of interstitial cystitis: a randomized, placebocontrolled study. J Urol 1996, 156:947\u2013952.","journal-title":"J Urol"},{"key":"37_CR46","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1097\/01.ju.0000154631.92150.ef","volume":"173","author":"CK Payne","year":"2005","unstructured":"Payne CK, Mosbaugh PG, Forrest JB, et al.: Intravesical resiniferatoxin for the treatment of interstitial cystitis: a randomized, double-blind, placebo-controlled trial. J Urol 2005, 173:1592\u20131594.","journal-title":"J Urol"}],"container-title":["Current Urology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11934-005-0037-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11934-005-0037-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11934-005-0037-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11934-005-0037-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,15]],"date-time":"2022-05-15T11:56:05Z","timestamp":1652615765000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11934-005-0037-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["37"],"URL":"https:\/\/doi.org\/10.1007\/s11934-005-0037-y","relation":{},"ISSN":["1527-2737","1534-6285"],"issn-type":[{"value":"1527-2737","type":"print"},{"value":"1534-6285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}