{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T03:08:10Z","timestamp":1786504090316,"version":"build-2736575974"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Treat Options Cardio Med"],"published-print":{"date-parts":[[2001,2]]},"DOI":"10.1007\/s11936-001-0081-y","type":"journal-article","created":{"date-parts":[[2007,6,3]],"date-time":"2007-06-03T12:56:13Z","timestamp":1180875373000},"page":"15-24","source":"Crossref","is-referenced-by-count":5,"title":["Floppy mitral valve, mitral valve prolapse, and mitral valvular regurgitation"],"prefix":"10.1007","volume":"3","author":[{"given":"Harisios","family":"Boudoulas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles F.","family":"Wooley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"81_CR1","volume-title":"Mitral Valve: Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation","author":"H Boudoulas","year":"2000","unstructured":"Boudoulas H, Wooley CF: Mitral Valve: Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation.edn 2, revised. Armonk, NY: Futura Publishing; 2000. Recent book that covers the entire spectrum of FMV\/MVP.","edition":"edn 2"},{"key":"81_CR2","first-page":"25","volume":"3","author":"CF Wooley","year":"1994","unstructured":"Wooley CF, Sparks EA, Boudoulas H: The floppy mitral valve-mitral valve prolapse-mitral valvular regurgitation triad. Am Coll Cardiol Curr J Rev 1994, 3:25\u201326.","journal-title":"Am Coll Cardiol Curr J Rev"},{"key":"81_CR3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/978-94-011-5254-9_12","volume-title":"Cardiac Arrhythmias, Pacing, and Electrophysiology","author":"H Boudoulas","year":"1998","unstructured":"Boudoulas H, Schaal SF, Wooley CF: Floppy mitral valve\/mitral valve prolapse: cardiac arrhythmias. In Cardiac Arrhythmias, Pacing, and Electrophysiology. Edited by Vardas PE: Boston: Kluwer Academic Publisher; 1998:89\u201395."},{"key":"81_CR4","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1161\/01.CIR.43.4.606","volume":"43","author":"JE Edwards","year":"1971","unstructured":"Edwards JE: Mitral insufficiency resulting from \u201covershooting\u201d of leaflets. Circulation 1971, 43:606\u2013612.","journal-title":"Circulation"},{"key":"81_CR5","volume-title":"Functional Abnormalities of the Aorta","author":"H Boudoulas","year":"1996","unstructured":"Boudoulas H, Toutouzas PK, Wooley CF: Functional Abnormalities of the Aorta. Armonk: Futura Publishing;1996."},{"issue":"suppl 2","key":"81_CR6","first-page":"S242","volume":"4","author":"H Boudoulas","year":"1995","unstructured":"Boudoulas H, Boudoulas D, Sparks EA, et al.: Left atrial performance indices in chronic mitral valve disease. J Heart Valve Dis 1995, 4(suppl 2):S242\u2013247.","journal-title":"J Heart Valve Dis"},{"key":"81_CR7","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/0002-8703(89)90594-2","volume":"118","author":"H Boudoulas","year":"1989","unstructured":"Boudoulas H, Kolibash AJ, Baker P, et al.: Mitral valve prolapse and the mitral valve prolapse syndrome: a diagnostic classification and pathogenesis of symptoms. Am Heart J 1989, 118:796\u2013818.","journal-title":"Am Heart J"},{"key":"81_CR8","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1136\/hrt.40.5.468","volume":"40","author":"MJ Davies","year":"1978","unstructured":"Davies MJ, Moore BP, Brainbridge MV: The floppy mitral valve: study of incidence, pathology, and complications in surgical, necropsy and forensic material. Br Heart J 1978, 40:468\u2013481.","journal-title":"Br Heart J"},{"key":"81_CR9","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1086\/302624","volume":"65","author":"S Disse","year":"1999","unstructured":"Disse S, Abergel E, Houd AM, et al.: Mapping of the first locus for autosomal dominant myxomatous mitral valve prolapse to chromosome 16p11.2-p12.1. Am J Hum Genet 1999, 65:1242\u20131251.","journal-title":"Am J Hum Genet"},{"key":"81_CR10","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/S0140-6736(82)92680-0","volume":"9","author":"RB Devereux","year":"1982","unstructured":"Devereux RB, Brown WT, Lutas EM, et al.: Association of mitral valve prolapse with low bodyweight and low blood pressure. Lancet 1982, 9:792\u2013795.","journal-title":"Lancet"},{"key":"81_CR11","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0002-8703(63)90375-2","volume":"66","author":"JB Barlow","year":"1963","unstructured":"Barlow JB, Pocock WA, Marchand P, et al.: The significance of late systolic murmurs. Am Heart J 1963, 66:443\u2013452.","journal-title":"Am Heart J"},{"key":"81_CR12","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0002-8703(96)90403-2","volume":"132","author":"MT Malkowski","year":"1996","unstructured":"Malkowski MT, Boudoulas H, Wooley CF, et al.: The spectrum of structural abnormalities in the floppy mitral valve: echocardiographic evaluation. Am Heart J 1996, 132:145\u2013151. Describes structural abnormalities in patients with FMV\/MVP.","journal-title":"Am Heart J"},{"key":"81_CR13","first-page":"29","volume":"17","author":"H Boudoulas","year":"1991","unstructured":"Boudoulas H, Kolibash AJ, Wooley CF: Mitral valve prolapse: a heterogeneous disorder. Primary Cardiol 1991, 17:29\u201343.","journal-title":"Primary Cardiol"},{"key":"81_CR14","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1056\/NEJM198511213132101","volume":"313","author":"RA Nishimura","year":"1985","unstructured":"Nishimura RA, McGoon MD, Shub C, et al.: Echocardiographically documented mitral valve prolapse: long-term follow-up of 237 patients. N Engl J Med 1985, 313:1305\u20131309.","journal-title":"N Engl J Med"},{"key":"81_CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199907013410101","volume":"341","author":"LA Freed","year":"1999","unstructured":"Freed LA, Levy D, Levine RA, et al.: Prevalence and clinical outcome of mitral valve prolapse. N Engl J Med 1999, 341:1\u20137.","journal-title":"N Engl J Med"},{"key":"81_CR16","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1001\/jama.1997.03540460058033","volume":"277","author":"AS Dajani","year":"1997","unstructured":"Dajani AS, Taubert KA, Wilson W, et al.: Prevention of bacterial endocarditis: recommendations by the American Heart Association. JAMA 1997, 277:1794\u20131801. This fundamental article provides guidelines for prophylaxis of infective endocarditis.","journal-title":"JAMA"},{"key":"81_CR17","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0002-9149(97)00445-1","volume":"80","author":"U Host","year":"1997","unstructured":"Host U, Kelbaek H, Hildebrandt P, et al.: Effect of ramipril on mitral regurgitation secondary to mitral valve prolapse. Am J Cardiol 1997, 80:655\u2013658.","journal-title":"Am J Cardiol"},{"key":"81_CR18","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0022-5223(94)70463-5","volume":"107","author":"LH Cohn","year":"1994","unstructured":"Cohn LH, Couper GS, Aranki SF, et al.: Long-term results of mitral valve reconstruction for regurgitation of the myxomatous mitral valve. J Thorac Cardiovasc Surg 1994, 107:143\u2013150. Article dealing with surgical reconstruction of the mitral valve in patients with FMV\/MVP.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"81_CR19","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1161\/01.CIR.61.6.1200","volume":"61","author":"H Boudoulas","year":"1980","unstructured":"Boudoulas H, Reynolds JC, Mazzaferri E, et al.: Metabolic studies in mitral valve prolapse syndrome. Circulation 1980, 61:1200\u20131205.","journal-title":"Circulation"},{"key":"81_CR20","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/0002-9149(83)90130-3","volume":"52","author":"FA Gaffney","year":"1983","unstructured":"Gaffney FA, Bastian BC, Lane LB, et al.: Abnormal cardiovascular regulation in the mitral valve prolapse syndrome. Am J Cardiol 1983, 52:316\u2013320.","journal-title":"Am J Cardiol"},{"key":"81_CR21","volume-title":"Moss and Adams\u2019 Heart Disease in Infants, Children and Adolescents","author":"H Boudoulas","year":"2000","unstructured":"Boudoulas H, Wooley CF: The floppy mitral valve, mitral valve prolapse, mitral valvular regurgitation.In Moss and Adams\u2019 Heart Disease in Infants, Children and Adolescents. edn 6. Edited by Moss AJ, Adams FH. Philadelphia: Lippincott, Williams, and Wilkins; 2000.","edition":"edn 6"}],"container-title":["Current Treatment Options in Cardiovascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11936-001-0081-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11936-001-0081-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11936-001-0081-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,22]],"date-time":"2020-04-22T17:43:31Z","timestamp":1587577411000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11936-001-0081-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,2]]}},"alternative-id":["81"],"URL":"https:\/\/doi.org\/10.1007\/s11936-001-0081-y","relation":{},"ISSN":["1092-8464","1534-3189"],"issn-type":[{"value":"1092-8464","type":"print"},{"value":"1534-3189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,2]]}}}