{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T15:18:40Z","timestamp":1760368720222},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2005,8,1]],"date-time":"2005-08-01T00:00:00Z","timestamp":1122854400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Treat Options Cardio Med"],"published-print":{"date-parts":[[2005,8]]},"DOI":"10.1007\/s11936-005-0042-y","type":"journal-article","created":{"date-parts":[[2007,6,4]],"date-time":"2007-06-04T14:28:43Z","timestamp":1180967323000},"page":"317-325","source":"Crossref","is-referenced-by-count":2,"title":["Treatment of heart failure with a normal ejection fraction"],"prefix":"10.1007","volume":"7","author":[{"given":"Shyam","family":"Bhakta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark E.","family":"Dunlap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"42_CR1","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1056\/NEJMoa032566","volume":"350","author":"MR Zile","year":"2004","unstructured":"Zile MR Baku CF, Gaasch WH: Diastolic heart failure\u2014abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med 2004, 350:1953\u20131959.","journal-title":"N Engl J Med"},{"key":"42_CR2","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1146\/annurev.med.55.091902.104417","volume":"55","author":"WH Gaasch","year":"2004","unstructured":"Gaasch WH, Zile MR: Left ventricular diastolic dysfunction and diastolic heart failure. Annu Rev Med 2004, 55:373\u2013394.","journal-title":"Annu Rev Med"},{"key":"42_CR3","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1056\/NEJMcp022709","volume":"351","author":"GP Aurigemma","year":"2004","unstructured":"Aurigemma GP, Gaasch WH: Diastolic heart failure. N Engl J Med 2004, 351:1097\u20131105. Comprehensive up-to-date review of DHF with thorough discussion of pathophysiology, diagnosis, and treatment.","journal-title":"N Engl J Med"},{"key":"42_CR4","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1056\/NEJMp048064","volume":"350","author":"MM Redfield","year":"2004","unstructured":"Redfield MM: Understanding \u201cdiastolic\u201d heart failure. N Engl J Med 2004, 350:1930\u20131931.","journal-title":"N Engl J Med"},{"key":"42_CR5","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ejheart.2004.01.005","volume":"6","author":"U Dahlstrom","year":"2004","unstructured":"Dahlstrom U: Can natriuretic peptides be used for the diagnosis of diastolic heart failure? Eur J Heart Fail 2004, 6:281\u2013287.","journal-title":"Eur J Heart Fail"},{"key":"42_CR6","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1016\/S0735-1097(01)01683-7","volume":"38","author":"SA Hunt","year":"2001","unstructured":"Hunt SA, Baker DW, Chin MH, et al.: ACC\/AHA guidelines for the evaluation and management of chronic heart failure in the adult. J Am Coll Cardiol 2001, 38:2101\u20132113. Most recent guidelines for diagnosis and management of HF. Excellent reading on diagnosis and pharmacologic management of systolic HF, although considerable discussion on DHF is available.","journal-title":"J Am Coll Cardiol"},{"key":"42_CR7","doi-asserted-by":"crossref","unstructured":"A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. The Beta-Blocker Evaluation of Survival Trial Investigators [no authors listed]. N EnglJ Med 2001, 344:1659\u20131667.","DOI":"10.1056\/NEJM200105313442202"},{"key":"42_CR8","doi-asserted-by":"crossref","unstructured":"The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial. CIBIS Investigators and Committees [no authors listed]. Lancet 1999, 353:3\u201313.","DOI":"10.1016\/S0140-6736(98)11181-9"},{"key":"42_CR9","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1001\/jama.287.7.883","volume":"287","author":"JM Foody","year":"2002","unstructured":"Foody JM, Parrell MK, Krumholz HM: Beta-blocker therapy in heart failure. JAMA 2002, 287:883\u2013889.","journal-title":"JAMA"},{"key":"42_CR10","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1056\/NEJMra000050","volume":"345","author":"KT Weber","year":"2001","unstructured":"Weber KT: Aldosterone in congestive heart failure. N Engl J Med 2001, 345:1689\u20131697.","journal-title":"N Engl J Med"},{"key":"42_CR11","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","volume":"341","author":"B Pitt","year":"1999","unstructured":"Pitt B, Zannad F, Remme WJ, et al.: The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 1999, 341:709\u2013717.","journal-title":"N Engl J Med"},{"key":"42_CR12","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1056\/NEJMoa030207","volume":"348","author":"B Pitt","year":"2003","unstructured":"Pitt B, Remme WJ, Zannad F, et al.: Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 2003, 348:1309\u20131321.","journal-title":"N Engl J Med"},{"issue":"suppl","key":"42_CR13","first-page":"S12","volume":"20","author":"V Papademetriou","year":"2003","unstructured":"Papademetriou V, Dunlap ME: Management of systolic heart failure. Cardiol Rev 2003, 20(suppl):S12-S20.","journal-title":"Cardiol Rev"},{"key":"42_CR14","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0140-6736(03)14285-7","volume":"362","author":"S Yusuf","year":"2003","unstructured":"Yusuf S, Pfeffer MA, Swedberg K, et al.: Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet 2003, 362:777\u2013781. First large-scale, randomized, placebo-controlled clinical trial of a pharmacologic agent showing statistically significant benefit in DHF. Sets the stage for ongoing clinical trials in DHF.","journal-title":"Lancet"},{"key":"42_CR15","doi-asserted-by":"crossref","first-page":"665","DOI":"10.3949\/ccjm.71.8.665","volume":"71","author":"S Bhakta","year":"2004","unstructured":"Bhakta S, Dunlap ME: Angiotensin-receptor blockers in heart failure: evidence from the CHARM trial. Clev Clin J Med 2004, 71:665\u2013673.","journal-title":"Clev Clin J Med"},{"key":"42_CR16","doi-asserted-by":"crossref","unstructured":"Introduction [no authors listed]. Cardiol Rev 2003, 20 (suppl):S2\u2013S3.","DOI":"10.1038\/sj.ijo.0802489"},{"key":"42_CR17","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1001\/jama.289.6.712","volume":"289","author":"H Krum","year":"2003","unstructured":"Krum H, Roecker EM, Mohacsi P, et al.: Effects of initiating carvedilol in patients with severe chronic heart failure. Results from the COPERNICUS study. JAMA 2003, 289:712\u2013718.","journal-title":"JAMA"},{"key":"42_CR18","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1056\/NEJM199605233342101","volume":"334","author":"M Packer","year":"1996","unstructured":"Packer M, Bristow MR, Cohn JN, et al.: The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 1996, 334:1349\u20131355.","journal-title":"N Engl J Med"},{"key":"42_CR19","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.ejheart.2004.02.003","volume":"6","author":"A Bergstrom","year":"2004","unstructured":"Bergstrom A, Anderson B, Edner M, et al.: Effect of carvedilol on diastolic function in patients with diastolic heart failure and preserved systolic function. Results of the Swedish Doppler echocardiographic study (SWEDIC). Eur J Heart Fail 2004, 6:453\u2013461.","journal-title":"Eur J Heart Fail"},{"key":"42_CR20","first-page":"1531","volume":"287","author":"Publication Committee for the VMAC Investigators","year":"2002","unstructured":"Publication Committee for the VMAC Investigators: Intravenous nesiritide vs. nitroglycerin for treatment of decompensated congestive heart failure. A randomized controlled trial. JAMA 2002, 287:1531\u20131540.","journal-title":"JAMA"},{"key":"42_CR21","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1001\/jama.289.6.730","volume":"289","author":"DJ Bradley","year":"2003","unstructured":"Bradley DJ, Bradley EA, Baughman KL, et al.: Cardiac resynchronization and death from progressive heart failure. JAMA 2003, 289:730\u2013740.","journal-title":"JAMA"},{"key":"42_CR22","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1056\/NEJMoa022479","volume":"348","author":"Y Kaneko","year":"2003","unstructured":"Kaneko Y: Cardiovascular effects of continuous positive airway pressure in patients with heart failure and obstructive sleep apnea. N Engl J Med 2003, 348:1233\u20131241.","journal-title":"N Engl J Med"}],"container-title":["Current Treatment Options in Cardiovascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11936-005-0042-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11936-005-0042-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11936-005-0042-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T20:52:32Z","timestamp":1559422352000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11936-005-0042-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["42"],"URL":"https:\/\/doi.org\/10.1007\/s11936-005-0042-y","relation":{},"ISSN":["1092-8464","1534-3189"],"issn-type":[{"value":"1092-8464","type":"print"},{"value":"1534-3189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}