{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T23:24:01Z","timestamp":1749857041490},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Treat Options Gastro"],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1007\/s11938-007-0072-5","type":"journal-article","created":{"date-parts":[[2008,3,15]],"date-time":"2008-03-15T14:46:26Z","timestamp":1205592386000},"page":"294-304","source":"Crossref","is-referenced-by-count":8,"title":["Functional heartburn, nonerosive reflux disease, and reflux esophagitis are all distinct conditions\u2014A debate: Pro"],"prefix":"10.1007","volume":"10","author":[{"given":"Tom\u00e1s","family":"Navarro-Rodriguez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronnie","family":"Fass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,3,16]]},"reference":[{"key":"72_CR1","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1056\/NEJM198608073150605","volume":"315","author":"S. Spechler","year":"1986","unstructured":"Spechler S, Goyal R: Barrett\u2019s esophagus. N Engl J Med 1986, 315:362\u2013371.","journal-title":"N Engl J Med"},{"key":"72_CR2","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1111\/j.1572-0241.2004.30390.x","volume":"99","author":"J. Labenz","year":"2004","unstructured":"Labenz J, Jaspersen D, Kulig M, et al.: Risk factors for erosive esophagitis: a multivariate analysis based on the ProGERD study initiative. Am J Gastroenterol 2004, 99:1652\u20131656.","journal-title":"Am J Gastroenterol"},{"key":"72_CR3","first-page":"1901","volume":"97","author":"R. Fass","year":"2002","unstructured":"Fass R, Ofman J: Gastroesophageal reflux disease\u2014should we adopt a new conceptual framework? Am J Gastroenterol 2002, 97:1901\u20131909.","journal-title":"Am J Gastroenterol"},{"key":"72_CR4","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0889-8553(02)00046-8","volume":"31","author":"R. Fass","year":"2002","unstructured":"Fass R: Gastroesophageal reflux disease revisited. Gastroenterol Clin North Am 2002, 31:S1\u2013S10.","journal-title":"Gastroenterol Clin North Am"},{"key":"72_CR5","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1159\/000080307","volume":"22","author":"R. Fass","year":"2004","unstructured":"Fass R: Distinct phenotypic presentations of gastroesophageal reflux disease: a new view of the natural history. Dig Dis 2004, 22:100\u2013107.","journal-title":"Dig Dis"},{"key":"72_CR6","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1111\/j.1572-0241.2004.04164.x","volume":"99","author":"F. Pace","year":"2004","unstructured":"Pace F, Bianchi Porro G: Gastroesophageal reflux disease: a typical spectrum disease (a new conceptual framework is not needed). Am J Gastroenterol 2004, 99:946\u2013949.","journal-title":"Am J Gastroenterol"},{"issue":"Suppl1","key":"72_CR7","first-page":"S13","volume":"13","author":"E. Quigley","year":"2001","unstructured":"Quigley E: Non-erosive reflux disease: a part of the spectrum of gastro-oesophageal reflux disease, a component of functional dyspepsia, or both? Eur J Gastroenterol Hepatol 2001, 13(Suppl 1):S13\u2013S18.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"72_CR8","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1097\/00004836-200605000-00002","volume":"40","author":"A. Agrawal","year":"2006","unstructured":"Agrawal A, Castell D. GERD is chronic but not progressive [editorial]. J Clin Gastroenterol 2006, 40:374\u2013375.","journal-title":"J Clin Gastroenterol"},{"key":"72_CR9","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1001\/archinte.166.9.965","volume":"166","author":"T. Kaltenbach","year":"2006","unstructured":"Kaltenbach T, Crockett S, Gerson L: Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. Arch Intern Med 2006, 166:965\u2013971.","journal-title":"Arch Intern Med"},{"key":"72_CR10","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1111\/j.1572-0241.2006.00631.x","volume":"101","author":"S. Hanna","year":"2006","unstructured":"Hanna S, Rastogi A, Weston A, et al.: Detection of Barrett\u2019s esophagus after endoscopic healing of erosive esophagitis. Am J Gastroenterol 2006, 101:1416\u20131420.","journal-title":"Am J Gastroenterol"},{"key":"72_CR11","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.dld.2003.10.012","volume":"36","author":"F. Pace","year":"2004","unstructured":"Pace F, Bollani S, Molteni P, Bianchi Porro G: Natural history of gastro-oesophageal reflux disease without oesophagitis (NERD)-a reappraisal 10 years on. Dig Liver Dis 2004, 36:111\u2013115.","journal-title":"Dig Liver Dis"},{"issue":"Suppl5","key":"72_CR12","first-page":"A62","volume":"55","author":"F. Pace","year":"2006","unstructured":"Pace F, Pallotta S, Molteni P, et al.: Natural history of NERD in 3 Italian tertiary referral centres after 5 years of follow-up [abstract]. Gut 2006, 55(Suppl 5):A62.","journal-title":"Gut"},{"key":"72_CR13","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1365-2036.2006.02747.x","volume":"23","author":"M. Shapiro","year":"2006","unstructured":"Shapiro M, Green C, Faybush E, et al.: The extent of oesophageal acid exposure overlap among the different gastro-oesophageal reflux disease groups. Aliment Pharmacol Ther 2006, 23:321\u2013329.","journal-title":"Aliment Pharmacol Ther"},{"key":"72_CR14","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/01.mcg.0000225631.07039.6d","volume":"41","author":"R. Fass","year":"2007","unstructured":"Fass R: Erosive esophagitis and nonerosive reflux disease (NERD): comparison of epidemiologic, physiologic, and therapeutic characteristics. J Clin Gastroenterol 2007, 41:131\u2013137.","journal-title":"J Clin Gastroenterol"},{"key":"72_CR15","first-page":"435","volume-title":"The Esophagus","author":"E. Klinkenberg-Knol","year":"1999","unstructured":"Klinkenberg-Knol E, Castell D: Clinical spectrum and diagnosis of gastroesophageal reflux disease. In The Esophagus, edn 2. Edited by Castell D, Richter J. Philadelphia: Lippincott Williams & Wilkins; 1999:435\u2013442.","edition":"edn 2"},{"key":"72_CR16","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3109\/00365529709011212","volume":"32","author":"T. Lind","year":"1997","unstructured":"Lind T, Havelund T, Carlsson R, et al.: Heartburn without oesophagitis: efficacy of omeprazole therapy and features determining therapeutic response. Scand J Gastroenterol 1997, 32:974\u2013979.","journal-title":"Scand J Gastroenterol"},{"key":"72_CR17","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1572-0241.2001.03511.x","volume":"96","author":"R. Fass","year":"2001","unstructured":"Fass R, Fennerty M, Vakil N: Nonerosive reflux disease\u2014current concepts and dilemmas. Am J Gastroenterol 2001, 96:303\u2013314.","journal-title":"Am J Gastroenterol"},{"key":"72_CR18","first-page":"1997","volume":"92","author":"B. Schenk","year":"1997","unstructured":"Schenk B, Kuipers E, Klinkenberg-Knol E: Omeprazole as a diagnostic tool in gastroesophageal reflux disease. Am J Gastroenterol 1997, 92:1997\u20132000.","journal-title":"Am J Gastroenterol"},{"key":"72_CR19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/00365529850166149","volume":"33","author":"F. Johnsson","year":"1998","unstructured":"Johnsson F, Weywadt L, Solhaug J, et al.: One-week omeprazole treatment in the diagnosis of gastro-oesophageal reflux disease. Scand J Gastroenterol 1998, 33:15\u201320.","journal-title":"Scand J Gastroenterol"},{"key":"72_CR20","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1001\/archinte.159.18.2161","volume":"159","author":"R. Fass","year":"1999","unstructured":"Fass R, Ofman J, Gralnek I, et al.: Clinical and economic assessment of the omeprazole test in patients with symptoms suggestive of gastroesophageal reflux disease. Arch Intern Med 1999, 159:2161\u20132168.","journal-title":"Arch Intern Med"},{"key":"72_CR21","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1136\/gut.51.6.885","volume":"51","author":"R. Fass","year":"2002","unstructured":"Fass R, Tougas G: Functional heartburn: the stimulus, the pain, and the brain. Gut 2002, 51:885\u2013892.","journal-title":"Gut"},{"key":"72_CR22","first-page":"128","volume":"126","author":"A. Hobson","year":"2004","unstructured":"Hobson A, Matthews P, Furlong P, Aziz Q: The role of esophageal afferent pathway sensitivity in non-erosive reflux disease [abstract]. Gastroenterology 2004, 126:128.","journal-title":"Gastroenterology"},{"key":"72_CR23","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1365-2982.2006.00761.x","volume":"18","author":"M. Young","year":"2006","unstructured":"Young M, Li ZS, Xu XR, et al.: Characterization of cortical potentials evoked by esophageal balloon distention and acid perfusion in patients with functional heartburn. Neurogastroenterol Motil 2006, 18:292\u2013299.","journal-title":"Neurogastroenterol Motil"},{"key":"72_CR24","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1111\/j.1572-0241.1999.00925.x","volume":"94","author":"S. Rodriguez-Stanley","year":"1999","unstructured":"Rodriguez-Stanley S, Robinson M, Earnest D, et al.: Esophageal hypersensitivity may be a major cause of heartburn. Am J Gastroenterol 1999, 94:628\u2013631.","journal-title":"Am J Gastroenterol"},{"key":"72_CR25","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/j.1572-0241.2006.00525.x","volume":"101","author":"M. Shapiro","year":"2006","unstructured":"Shapiro M, Green C, Bautista J, et al.: Functional heartburn patients demonstrate traits of functional bowel disorder but lack a uniform increase of chemoreceptor sensitivity to acid. Am J Gastroenterol 2006, 101:1084\u20131091.","journal-title":"Am J Gastroenterol"},{"key":"72_CR26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1365-2036.2004.01998.x","volume":"20","author":"M. Frazzoni","year":"2004","unstructured":"Frazzoni M, De Micheli E, Zentilin P, Savarino V: Pathophysiological characteristics of patients with non-erosive reflux disease differ from those of patients with functional heartburn. Aliment Pharmacol Ther 2004, 20:81\u201388.","journal-title":"Aliment Pharmacol Ther"},{"key":"72_CR27","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1046\/j.1365-2036.2003.01423.x","volume":"17","author":"S.D. Martinez","year":"2003","unstructured":"Martinez SD, Malagon IB, Garewal HS, et al.: Non-erosive reflux disease (NERD)\u2014acid reflux and symptom patterns. Aliment Pharmacol Ther 2003, 17:537\u2013545.","journal-title":"Aliment Pharmacol Ther"},{"key":"72_CR28","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1046\/j.1365-2036.2003.01702.x","volume":"18","author":"M. Cicala","year":"2003","unstructured":"Cicala M, Emerenziani S, Caviglia R, et al.: Intra-oesophageal distribution and perception of acid reflux in patients with non-erosive gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2003, 18:605\u2013613.","journal-title":"Aliment Pharmacol Ther"},{"key":"72_CR29","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S1542-3565(05)00021-2","volume":"3","author":"C. Prakash","year":"2005","unstructured":"Prakash C, Clouse R: Value of extended recording time with wireless pH monitoring in evaluating gastroesophageal reflux disease. Clin Gastroenterol Hepatol 2005, 3:329\u2013334.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"72_CR30","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/S0016-5107(05)00317-2","volume":"62","author":"Y.C. Lee","year":"2005","unstructured":"Lee YC, Wang HP, Chiu HM, et al.: Patients with functional heartburn are more likely to report retrosternal discomfort during wireless pH monitoring. Gastrointest Endosc 2005, 62:834\u2013841.","journal-title":"Gastrointest Endosc"},{"key":"72_CR31","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/j.1572-0241.2005.40978.x","volume":"100","author":"R. Caviglia","year":"2005","unstructured":"Caviglia R, Ribolsi M, Maggiano N, et al.: Dilated intercellular spaces of esophageal epithelium in nonerosive reflux disease patients with physiological esophageal acid exposure. Am J Gastroenterol 2005, 100:543\u2013548.","journal-title":"Am J Gastroenterol"},{"key":"72_CR32","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1136\/gut.39.2.151","volume":"39","author":"N. Schindlbeck","year":"1996","unstructured":"Schindlbeck N, Wiebecke B, Klauser A, et al.: Diagnostic value of histology in non-erosive gastrooesophageal reflux disease. Gut 1996, 39:151\u2013154.","journal-title":"Gut"},{"key":"72_CR33","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1136\/gut.32.8.845","volume":"32","author":"F. Pace","year":"1991","unstructured":"Pace F, Santalucia F, Bianchi Porro G: Natural history of gastro-oesophageal reflux disease without oesophagitis. Gut 1991, 32:845\u2013848.","journal-title":"Gut"},{"key":"72_CR34","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1136\/gut.35.1.8","volume":"35","author":"E. Kuster","year":"1994","unstructured":"Kuster E, Ros E, Toledo-Pimentel V, et al.: Predictive factors of the long term outcome in gastro-oesophageal reflux disease: six year follow up of 107 patients. Gut 1994, 35:8\u201314.","journal-title":"Gut"},{"key":"72_CR35","first-page":"37","volume":"92","author":"J. Isolauri","year":"1997","unstructured":"Isolauri J, Luostarinen M, Isolauri E, et al.: Natural course of gastroesophageal reflux disease: 17\u201322 year follow-up of 60 patients. Am J Gastroenterol 1997, 92:37\u201341.","journal-title":"Am J Gastroenterol"},{"key":"72_CR36","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/gut.38.4.481","volume":"38","author":"N. McDougall","year":"1996","unstructured":"McDougall N, Johnston B, Kee F, et al.: Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life. Gut 1996, 38:481\u2013486.","journal-title":"Gut"},{"key":"72_CR37","first-page":"1161","volume":"9","author":"N. McDougall","year":"1997","unstructured":"McDougall N, Johnston B, Collins J, et al.: Disease progression in gastro-oesophageal reflux disease as determined by repeat oesophageal pH monitoring and endoscopy 3 to 4.5 years after diagnosis. Eur J Gastroenterol Hepatol 1997, 9:1161\u20131167.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"72_CR38","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1046\/j.1440-1746.2002.02783.x","volume":"17","author":"N. Manabe","year":"2002","unstructured":"Manabe N, Yoshihara M, Sasaki A, et al.: Clinical characteristics and natural history of patients with low-grade reflux esophagitis. J Gastroenterol Hepatol 2002, 17:949\u2013954.","journal-title":"J Gastroenterol Hepatol"},{"key":"72_CR39","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1111\/j.1572-0241.2006.00829.x","volume":"101","author":"J. Labenz","year":"2006","unstructured":"Labenz J, Nocon M, Lind T, et al.: Prospective follow-up data from the ProGERD study suggest that GERD is not a categorical disease. Am J Gastroenterol 2006, 101:2457\u20132462.","journal-title":"Am J Gastroenterol"},{"key":"72_CR40","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1365-2036.2006.02763.x","volume":"23","author":"S. Willich","year":"2006","unstructured":"Willich S, Nocon M, Kulig M, et al.: Cost-of-disease analysis in patients with gastro-oesophageal reflux disease and Barrett\u2019s mucosa. Aliment Pharmacol Ther 2006, 23:371\u2013376.","journal-title":"Aliment Pharmacol Ther"},{"key":"72_CR41","first-page":"712","volume":"95","author":"A. Garrido Serrano","year":"2003","unstructured":"Garrido Serrano A, Guerrero Igea FJ, Lepe Jim\u00e9nez JA, Perianes Hern\u00e1ndez C: Clinical features and endoscopic progression of gastroesophageal reflux disease. Rev Esp Enferm Dig 2003, 95:712\u2013716.","journal-title":"Rev Esp Enferm Dig"},{"key":"72_CR42","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1097\/00004836-200605000-00007","volume":"40","author":"S. Sontag","year":"2006","unstructured":"Sontag S, Sonnenberg A, Schnell T, et al.: The long-term natural history of gastroesophageal reflux disease. J Clin Gastroenterol 2006, 40:398\u2013404.","journal-title":"J Clin Gastroenterol"},{"key":"72_CR43","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.dld.2005.10.011","volume":"38","author":"K.D. Bardhan","year":"2006","unstructured":"Bardhan KD, Royston C, Nayyar AK: Reflux rising! An essay on witnessing a disease in evolution. Dig Liver Dis 2006, 38:163\u2013168","journal-title":"Dig Liver Dis"},{"key":"72_CR44","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1053\/gast.2002.30301","volume":"122","author":"A. Cameron","year":"2002","unstructured":"Cameron A, Lagergren J, Henriksson C, et al.: Gastroesophageal reflux disease in monozygotic and dizygotic twins. Gastroenterology 2002, 122:55\u201359.","journal-title":"Gastroenterology"},{"key":"72_CR45","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1053\/gast.1997.v113.pm9352846","volume":"113","author":"Y. Romero","year":"1997","unstructured":"Romero Y, Cameron A, Locke G, 3rd, et al.: Familial aggregation of gastroesophageal reflux in patients with Barrett\u2019s esophagus and esophageal adenocarcinoma. Gastroenterology 1997, 113:1449\u20131456.","journal-title":"Gastroenterology"},{"issue":"3Suppl","key":"72_CR46","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1016\/S0002-9270(03)00012-1","volume":"98","author":"E. Quigley","year":"2003","unstructured":"Quigley E: Factors that influence therapeutic outcomes in symptomatic gastroesophageal reflux disease. Am J Gastroenterol 2003, 98(3 Suppl):S24\u2013S30.","journal-title":"Am J Gastroenterol"},{"key":"72_CR47","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1572-0241.2002.05532.x","volume":"97","author":"D. Castell","year":"2002","unstructured":"Castell D, Kahrilas P, Richter J, et al.: Esomeprazole (40 mg) compared with lansoprazole (30 mg) in the treatment of erosive esophagitis. Am J Gastroenterol 2002, 97:575\u2013583.","journal-title":"Am J Gastroenterol"},{"key":"72_CR48","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/0016-5085(88)90162-X","volume":"95","author":"D. Hetzel","year":"1988","unstructured":"Hetzel D, Dent J, Reed W, et al.: Healing and relapse of severe peptic esophagitis after treatment with omeprazole. Gastroenterology 1988, 95:903\u2013912.","journal-title":"Gastroenterology"},{"key":"72_CR49","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1053\/gast.2001.24841","volume":"120","author":"D. Sifrim","year":"2001","unstructured":"Sifrim D, Holloway R, Silny J, et al.: Acid, nonacid, and gas reflux in patients with gastroesophageal reflux disease during ambulatory 24-hour pH-impedance recordings. Gastroenterology 2001, 120:1588\u20131598.","journal-title":"Gastroenterology"},{"key":"72_CR50","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/S0016-5085(98)70014-9","volume":"115","author":"R. Fass","year":"1988","unstructured":"Fass R, Naliboff B, Higa L, et al.: Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans. Gastroenterology 1988, 115:1363\u20131373.","journal-title":"Gastroenterology"},{"key":"72_CR51","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1053\/gast.2001.24840","volume":"120","author":"M. Vela","year":"2001","unstructured":"Vela M, Camacho-Lobato L, Srinivasan R, et al.: Simultaneous intraesophageal impedance and pH measurement of acid and nonacid gastroesophageal reflux: effect of omeprazole. Gastroenterology 2001, 120:1599\u20131606.","journal-title":"Gastroenterology"},{"key":"72_CR52","first-page":"19","volume":"30","author":"I. Wiklund","year":"1998","unstructured":"Wiklund I, Bardhan K, Muller-Lissner S, et al.: Quality of life during acute and intermittent treatment of gastro-oesophageal reflux disease with omeprazole compared with ranitidine. Results from a multicentre clinical trial. The European Study Group. Ital J Gastroenterol Hepatol 1998, 30:19\u201327.","journal-title":"Ital J Gastroenterol Hepatol"},{"key":"72_CR53","doi-asserted-by":"crossref","first-page":"483","DOI":"10.2165\/00019053-199916050-00006","volume":"16","author":"N. Stalhammer","year":"1999","unstructured":"Stalhammer N, Carlsson J, Peacock R, et al.: Cost effectiveness of omeprazole and ranitidine in intermittent treatment of symptomatic gastro-oesophageal reflux disease. Pharmacoeconomics 1999, 16:483\u2013497.","journal-title":"Pharmacoeconomics"},{"key":"72_CR54","first-page":"395","volume":"95","author":"L. Gerson","year":"2000","unstructured":"Gerson L, Robbins A, Garbert A, et al.: A cost-effectiveness analysis of prescribing strategies in the management of gastroesophageal reflux disease. Gastroenterology 2000, 95:395\u2013407.","journal-title":"Gastroenterology"},{"key":"72_CR55","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1046\/j.1365-2036.1997.00185.x","volume":"11","author":"J.P. Galmiche","year":"1997","unstructured":"Galmiche JP, Barthelemy P, Hamelin B: Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride. Aliment Pharmacol Ther 1997, 11:765\u2013773.","journal-title":"Aliment Pharmacol Ther"},{"key":"72_CR56","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S1542-3565(04)00288-5","volume":"2","author":"B. Dean","year":"2004","unstructured":"Dean B, Gano A, Jr, Knight K, et al.: Effectiveness of proton pump inhibitors in nonerosive reflux disease. Clin Gastroenterol Hepatol 2004, 2:656\u2013664.","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Current Treatment Options in Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11938-007-0072-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11938-007-0072-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11938-007-0072-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T23:42:17Z","timestamp":1630885337000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11938-007-0072-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":56,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["72"],"URL":"https:\/\/doi.org\/10.1007\/s11938-007-0072-5","relation":{},"ISSN":["1092-8472","1534-309X"],"issn-type":[{"value":"1092-8472","type":"print"},{"value":"1534-309X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}