{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T13:45:10Z","timestamp":1747835110882},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T00:00:00Z","timestamp":1541635200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Treat Options Gastro"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1007\/s11938-018-0212-0","type":"journal-article","created":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T02:00:08Z","timestamp":1541642408000},"page":"528-540","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Role of Botulinum Toxin Injections for Esophageal Motility Disorders"],"prefix":"10.1007","volume":"16","author":[{"given":"Jessica L.","family":"Sterling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Schey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zubair","family":"Malik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,11,8]]},"reference":[{"issue":"8","key":"212_CR1","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s11894-017-0576-7","volume":"19","author":"WOA Rohof","year":"2017","unstructured":"\u2022 Rohof WOA, Bredenoord AJ. Chicago classification of esophageal motility disorders: lessons learned. Curr Gastroenterol Rep. 2017;19(8):37. https:\/\/doi.org\/10.1007\/s11894-017-0576-7 This review highlights the advancements in diagnosis of esophageal motility disorders.","journal-title":"Curr Gastroenterol Rep"},{"issue":"6","key":"212_CR2","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.3390\/toxins7061882","volume":"7","author":"G Brisinda","year":"2015","unstructured":"Brisinda G, Sivestrini N, Bianco G, Maria G. Treatment of gastrointestinal sphincters spasms with botulinum toxin a. Toxins (Basel). 2015;7(6):1882\u2013916. https:\/\/doi.org\/10.3390\/toxins7061882 .","journal-title":"Toxins (Basel)"},{"issue":"6","key":"212_CR3","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1038\/nrgastro.2015.45","volume":"12","author":"J Tack","year":"2015","unstructured":"Tack J, Zaninotto G. Therapeutic options in oesophageal dysphagia. Nat Rev Gastroenterol Hepatol. 2015;12(6):332\u201341. https:\/\/doi.org\/10.1038\/nrgastro.2015.45 .","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"5","key":"212_CR4","doi-asserted-by":"publisher","first-page":"208","DOI":"10.3390\/toxins10050208","volume":"10","author":"Elena Fonfria","year":"2018","unstructured":"Fonfria E, Maignel J, Lezmi S, Martin V, Splevins A, Shubber S et al. The expanding therapeutic utility of botulinum neurotoxins. Toxins (Basel). 2018;10(5). https:\/\/doi.org\/10.3390\/toxins10050208 .","journal-title":"Toxins"},{"issue":"3","key":"212_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/dote.12491","volume":"30","author":"FB Hoeij van","year":"2017","unstructured":"\u2022 van Hoeij FB, Tack JF, Pandolfino JE, Sternbach JM, Roman S, Smout AJ, et al. Complications of botulinum toxin injections for treatment of esophageal motility disorders\u2020. Dis Esophagus. 2017;30(3):1\u20135. https:\/\/doi.org\/10.1111\/dote.12491 This is the only analysis that highlights the important complications of esophageal BTX injections.","journal-title":"Dis Esophagus"},{"issue":"4","key":"212_CR6","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1097\/MOG.0000000000000187","volume":"31","author":"S Roman","year":"2015","unstructured":"Roman S, Kahrilas PJ. Distal esophageal spasm. Curr Opin Gastroenterol. 2015;31(4):328\u201333. https:\/\/doi.org\/10.1097\/MOG.0000000000000187 .","journal-title":"Curr Opin Gastroenterol"},{"issue":"6","key":"212_CR7","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1097\/MCG.0000000000000317","volume":"49","author":"FM Zerbib","year":"2015","unstructured":"Zerbib FM, Roman SM. Current therapeutic options for esophageal motor disorders as defined by the Chicago classification. J Clin Gastroenterol. 2015;49(6):451\u201360.","journal-title":"J Clin Gastroenterol"},{"issue":"7","key":"212_CR8","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1038\/ajg.2015.154","volume":"110","author":"SK Ratuapli","year":"2015","unstructured":"Ratuapli SK, Crowell MD, DiBaise JK, Vela MF, Ramirez FC, Burdick GE, et al. Opioid-induced esophageal dysfunction (OIED) in patients on chronic opioids. Am J Gastroenterol. 2015;110(7):979\u201384. https:\/\/doi.org\/10.1038\/ajg.2015.154 .","journal-title":"Am J Gastroenterol"},{"issue":"9","key":"212_CR9","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1111\/nmo.12625","volume":"27","author":"FB Hoeij van","year":"2015","unstructured":"van Hoeij FB, Smout AJ, Bredenoord AJ. Characterization of idiopathic esophagogastric junction outflow obstruction. Neurogastroenterol Motil. 2015;27(9):1310\u20136. https:\/\/doi.org\/10.1111\/nmo.12625 .","journal-title":"Neurogastroenterol Motil"},{"issue":"2","key":"212_CR10","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/j.1365-2982.2010.01604.x","volume":"23","author":"RF Porter","year":"2011","unstructured":"Porter RF, Gyawali CP. Botulinum toxin injection in dysphagia syndromes with preserved esophageal peristalsis and incomplete lower esophageal sphincter relaxation. Neurogastroenterol Motil. 2011;23(2):139\u201344,e27\u20138. https:\/\/doi.org\/10.1111\/j.1365-2982.2010.01604.x .","journal-title":"Neurogastroenterol Motil"},{"issue":"12","key":"212_CR11","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1007\/s11605-009-0975-7","volume":"13","author":"JR Scherer","year":"2009","unstructured":"Scherer JR, Kwiatek MA, Soper NJ, Pandolfino JE, Kahrilas PJ. Functional esophagogastric junction obstruction with intact peristalsis: a heterogeneous syndrome sometimes akin to achalasia. J Gastrointest Surg. 2009;13(12):2219\u201325. https:\/\/doi.org\/10.1007\/s11605-009-0975-7 .","journal-title":"J Gastrointest Surg"},{"issue":"6","key":"212_CR12","doi-asserted-by":"publisher","first-page":"e13061","DOI":"10.1111\/nmo.13061","volume":"29","author":"F. C. Okeke","year":"2017","unstructured":"Okeke FC, Raja S, Lynch KL, Dhalla S, Nandwani M, Stein EM et al. What is the clinical significance of esophagogastric junction outflow obstruction? evaluation of 60 patients at a tertiary referral center. Neurogastroenterol Motil. 2017;29(6). https:\/\/doi.org\/10.1111\/nmo.13061 .","journal-title":"Neurogastroenterology & Motility"},{"issue":"6","key":"212_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/dote\/dox004","volume":"30","author":"KL Lynch","year":"2017","unstructured":"Lynch KL, Yang YX, Metz DC, Falk GW. Clinical presentation and disease course of patients with esophagogastric junction outflow obstruction. Dis Esophagus. 2017;30(6):1\u20136. https:\/\/doi.org\/10.1093\/dote\/dox004 .","journal-title":"Dis Esophagus"},{"issue":"6","key":"212_CR14","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1016\/j.cgh.2015.12.041","volume":"14","author":"SB Clayton","year":"2016","unstructured":"Clayton SB, Patel R, Richter JE. Functional and anatomic esophagogastic junction outflow obstruction: manometry, timed barium esophagram findings, and treatment outcomes. Clin Gastroenterol Hepatol. 2016;14(6):907\u201311. https:\/\/doi.org\/10.1016\/j.cgh.2015.12.041 .","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"212_CR15","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1111\/nmo.12708","volume":"28","author":"MT P\u00e9rez-Fern\u00e1ndez","year":"2016","unstructured":"P\u00e9rez-Fern\u00e1ndez MT, Santander C, Marinero A, Burgos-Santamar\u00eda D, Chavarr\u00eda-Herbozo C. Characterization and follow-up of esophagogastric junction outflow obstruction detected by high resolution manometry. Neurogastroenterol Motil. 2016;28(1):116\u201326. https:\/\/doi.org\/10.1111\/nmo.12708 .","journal-title":"Neurogastroenterol Motil"},{"issue":"8","key":"212_CR16","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1111\/dote.12282","volume":"28","author":"S Marjoux","year":"2015","unstructured":"Marjoux S, Brochard C, Roman S, Gincul R, Pagenault M, Ponchon T, et al. Botulinum toxin injection for hypercontractile or spastic esophageal motility disorders: may high-resolution manometry help to select cases? Dis Esophagus. 2015;28(8):735\u201341. https:\/\/doi.org\/10.1111\/dote.12282 .","journal-title":"Dis Esophagus"},{"issue":"9","key":"212_CR17","doi-asserted-by":"publisher","first-page":"e256","DOI":"10.1111\/j.1365-2982.2010.01511.x","volume":"22","author":"DC Sadowski","year":"2010","unstructured":"Sadowski DC, Ackah F, Jiang B, Svenson LW. Achalasia: incidence, prevalence and survival. A population-based study. Neurogastroenterol Motil. 2010;22(9):e256\u201361. https:\/\/doi.org\/10.1111\/j.1365-2982.2010.01511.x .","journal-title":"Neurogastroenterol Motil"},{"issue":"1","key":"212_CR18","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1067\/j.cpsurg.2018.01.001","volume":"55","author":"F Schlottmann","year":"2018","unstructured":"Schlottmann F, Herbella F, Allaix ME, Patti MG. Modern management of esophageal achalasia: from pathophysiology to treatment. Curr Probl Surg. 2018;55(1):10\u201337. https:\/\/doi.org\/10.1067\/j.cpsurg.2018.01.001 .","journal-title":"Curr Probl Surg"},{"issue":"1","key":"212_CR19","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2214\/ajr.146.1.21","volume":"146","author":"WJ Dodds","year":"1986","unstructured":"Dodds WJ, Stewart ET, Kishk SM, Kahrilas PJ, Hogan WJ. Radiologic amyl nitrite test for distinguishing pseudoachalasia from idiopathic achalasia. AJR Am J Roentgenol. 1986;146(1):21\u20133. https:\/\/doi.org\/10.2214\/ajr.146.1.21 .","journal-title":"American Journal of Roentgenology"},{"key":"212_CR20","doi-asserted-by":"publisher","unstructured":"Lai CN, Krishnan K, Kim MP, Dunkin BJ, Gaur P. Pseudoachalasia presenting 20 years after Nissen fundoplication: a case report. J Cardiothorac Surg. 2016;11(1):96. https:\/\/doi.org\/10.1186\/s13019-016-0495-y .","DOI":"10.1186\/s13019-016-0495-y"},{"issue":"39","key":"212_CR21","doi-asserted-by":"publisher","first-page":"8670","DOI":"10.3748\/wjg.v22.i39.8670","volume":"22","author":"DS Uppal","year":"2016","unstructured":"Uppal DS, Wang AY. Update on the endoscopic treatments for achalasia. World J Gastroenterol. 2016;22(39):8670\u201383. https:\/\/doi.org\/10.3748\/wjg.v22.i39.8670 .","journal-title":"World J Gastroenterol"},{"key":"212_CR22","doi-asserted-by":"publisher","first-page":"i2785","DOI":"10.1136\/bmj.i2785","volume":"354","author":"SN Stavropoulos","year":"2016","unstructured":"Stavropoulos SN, Friedel D, Modayil R, Parkman HP. Diagnosis and management of esophageal achalasia. BMJ. 2016;354:i2785.","journal-title":"BMJ"},{"issue":"8","key":"212_CR23","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1038\/ajg.2013.196","volume":"108","author":"Michael F Vaezi","year":"2013","unstructured":"Vaezi MF, Pandolfino JE, Vela MF. ACG clinical guideline: diagnosis and management of achalasia. Am J Gastroenterol. 2013;108(8):1238\u201349; quiz50. https:\/\/doi.org\/10.1038\/ajg.2013.196 .","journal-title":"The American Journal of Gastroenterology"},{"issue":"1","key":"212_CR24","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1097\/SLA.0b013e31818e43ab","volume":"249","author":"GM Campos","year":"2009","unstructured":"Campos GM, Vittinghoff E, Rabl C, Takata M, Gadenst\u00e4tter M, Lin F, et al. Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis. Ann Surg. 2009;249(1):45\u201357. https:\/\/doi.org\/10.1097\/SLA.0b013e31818e43ab .","journal-title":"Ann Surg"},{"issue":"4","key":"212_CR25","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1097\/MCG.0000000000000966","volume":"52","author":"I Smith","year":"2018","unstructured":"Smith I, Kahaleh M. An update on current management strategies for achalasia and future perspectives. J Clin Gastroenterol. 2018;52(4):277\u201386. https:\/\/doi.org\/10.1097\/MCG.0000000000000966 .","journal-title":"J Clin Gastroenterol"},{"issue":"3","key":"212_CR26","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1097\/01.sla.0000114217.52941.c5","volume":"239","author":"G Zaninotto","year":"2004","unstructured":"Zaninotto G, Annese V, Costantini M, Del Genio A, Costantino M, Epifani M, et al. Randomized controlled trial of botulinum toxin versus laparoscopic heller myotomy for esophageal achalasia. Ann Surg. 2004;239(3):364\u201370.","journal-title":"Ann Surg"},{"issue":"11","key":"212_CR27","doi-asserted-by":"publisher","first-page":"2303","DOI":"10.1007\/s10620-008-0637-8","volume":"54","author":"L Wang","year":"2009","unstructured":"Wang L, Li YM, Li L. Meta-analysis of randomized and controlled treatment trials for achalasia. Dig Dis Sci. 2009;54(11):2303\u201311. https:\/\/doi.org\/10.1007\/s10620-008-0637-8 .","journal-title":"Dig Dis Sci"},{"key":"212_CR28","doi-asserted-by":"publisher","first-page":"CD005046","DOI":"10.1002\/14651858.CD005046.pub3","volume":"12","author":"JE Leyden","year":"2014","unstructured":"Leyden JE, Moss AC, MacMathuna P. Endoscopic pneumatic dilation versus botulinum toxin injection in the management of primary achalasia. Cochrane Database Syst Rev. 2014;12:CD005046. https:\/\/doi.org\/10.1002\/14651858.CD005046.pub3 .","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"212_CR29","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1007\/s00464-016-5151-z","volume":"31","author":"HJ Miller","year":"2017","unstructured":"Miller HJ, Neupane R, Fayezizadeh M, Majumder A, Marks JM. POEM is a cost-effective procedure: cost-utility analysis of endoscopic and surgical treatment options in the management of achalasia. Surg Endosc. 2017;31(4):1636\u201342. https:\/\/doi.org\/10.1007\/s00464-016-5151-z .","journal-title":"Surg Endosc"},{"issue":"5","key":"212_CR30","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1097\/01.sla.0000217524.75529.2d","volume":"243","author":"CD Smith","year":"2006","unstructured":"Smith CD, Stival A, Howell DL, Swafford V. Endoscopic therapy for achalasia before Heller myotomy results in worse outcomes than Heller myotomy alone. Ann Surg. 2006;243(5):579\u201384;discussion 84\u20136. https:\/\/doi.org\/10.1097\/01.sla.0000217524.75529.2d .","journal-title":"Ann Surg"},{"issue":"5","key":"212_CR31","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1007\/s00464-014-3782-5","volume":"29","author":"SB Orenstein","year":"2015","unstructured":"Orenstein SB, Raigani S, Wu YV, Pauli EM, Phillips MS, Ponsky JL, et al. Peroral endoscopic myotomy (POEM) leads to similar results in patients with and without prior endoscopic or surgical therapy. Surg Endosc. 2015;29(5):1064\u201370. https:\/\/doi.org\/10.1007\/s00464-014-3782-5 .","journal-title":"Surg Endosc"},{"issue":"7","key":"212_CR32","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1007\/s11605-013-2193-6","volume":"17","author":"A Sharata","year":"2013","unstructured":"Sharata A, Kurian AA, Dunst CM, Bhayani NH, Reavis KM, Swanstr\u00f6m LL. Peroral endoscopic myotomy (POEM) is safe and effective in the setting of prior endoscopic intervention. J Gastrointest Surg. 2013;17(7):1188\u201392. https:\/\/doi.org\/10.1007\/s11605-013-2193-6 .","journal-title":"J Gastrointest Surg"},{"issue":"8","key":"212_CR33","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1111\/jgh.12570","volume":"29","author":"T Ling","year":"2014","unstructured":"Ling T, Guo H, Zou X. Effect of peroral endoscopic myotomy in achalasia patients with failure of prior pneumatic dilation: a prospective case-control study. J Gastroenterol Hepatol. 2014;29(8):1609\u201313. https:\/\/doi.org\/10.1111\/jgh.12570 .","journal-title":"J Gastroenterol Hepatol"},{"issue":"8","key":"212_CR34","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1111\/jgh.13408","volume":"31","author":"N Gunasingam","year":"2016","unstructured":"Gunasingam N, Perczuk A, Talbot M, Kaffes A, Saxena P. Update on therapeutic interventions for the management of achalasia. J Gastroenterol Hepatol. 2016;31(8):1422\u20138. https:\/\/doi.org\/10.1111\/jgh.13408 .","journal-title":"J Gastroenterol Hepatol"},{"issue":"2","key":"212_CR35","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/S1590-8658(02)80238-9","volume":"34","author":"V D\u2019Onofrio","year":"2002","unstructured":"D\u2019Onofrio V, Miletto P, Leandro G, Iaquinto G. Long-term follow-up of achalasia patients treated with botulinum toxin. Dig Liver Dis. 2002;34(2):105\u201310.","journal-title":"Dig Liver Dis"},{"key":"212_CR36","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1016\/j.amjmed.2018.02.031","volume":"131","author":"M Khalaf","year":"2018","unstructured":"Khalaf M, Chowdhary S, Elias PS, Castell D. Distal esophageal spasm: a review. Am J Med. 2018;131:1034\u201340. https:\/\/doi.org\/10.1016\/j.amjmed.2018.02.031 .","journal-title":"Am J Med"},{"issue":"2","key":"212_CR37","doi-asserted-by":"publisher","first-page":"A25","DOI":"10.1016\/j.cgh.2013.08.035","volume":"12","author":"HU Schepper De","year":"2014","unstructured":"De Schepper HU, Smout AJ, Bredenoord AJ. Distal esophageal spasm evolving to achalasia in high resolution. Clin Gastroenterol Hepatol. 2014;12(2):A25\u20136. https:\/\/doi.org\/10.1016\/j.cgh.2013.08.035 .","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"5","key":"212_CR38","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1111\/j.1442-2050.2012.01377.x","volume":"26","author":"LH Fontes","year":"2013","unstructured":"Fontes LH, Herbella FA, Rodriguez TN, Trivino T, Farah JF. Progression of diffuse esophageal spasm to achalasia: incidence and predictive factors. Dis Esophagus. 2013;26(5):470\u20134. https:\/\/doi.org\/10.1111\/j.1442-2050.2012.01377.x .","journal-title":"Dis Esophagus"},{"issue":"9","key":"212_CR39","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1007\/s10620-005-2903-3","volume":"50","author":"SS Khatami","year":"2005","unstructured":"Khatami SS, Khandwala F, Shay SS, Vaezi MF. Does diffuse esophageal spasm progress to achalasia? A prospective cohort study. Dig Dis Sci. 2005;50(9):1605\u201310. https:\/\/doi.org\/10.1007\/s10620-005-2903-3 .","journal-title":"Dig Dis Sci"},{"issue":"1","key":"212_CR40","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.gtc.2012.11.002","volume":"42","author":"S Roman","year":"2013","unstructured":"Roman S, Kahrilas PJ. Management of spastic disorders of the esophagus. Gastroenterol Clin N Am. 2013;42(1):27\u201343. https:\/\/doi.org\/10.1016\/j.gtc.2012.11.002 .","journal-title":"Gastroenterol Clin N Am"},{"issue":"9","key":"212_CR41","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1016\/j.cgh.2013.03.021","volume":"11","author":"T Vanuytsel","year":"2013","unstructured":"\u2022 Vanuytsel T, Bisschops R, Farr\u00e9 R, Pauwels A, Holvoet L, Arts J, et al. Botulinum toxin reduces Dysphagia in patients with nonachalasia primary esophageal motility disorders. Clin Gastroenterol Hepatol. 2013;11(9):1115\u201321.e2. https:\/\/doi.org\/10.1016\/j.cgh.2013.03.021 This is the only double-blinded, placebo-controlled trial to evaluate BTX injection therapy for nonachalasia motility disorders.","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"9","key":"212_CR42","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1016\/j.cgh.2013.04.009","volume":"11","author":"MF Vaezi","year":"2013","unstructured":"Vaezi MF. Botulinum toxin in nonachalasia motility disorders: a welcomed therapy in an area with limited therapeutic options. Clin Gastroenterol Hepatol. 2013;11(9):1122\u20134. https:\/\/doi.org\/10.1016\/j.cgh.2013.04.009 .","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"Suppl 2 UCTN","key":"212_CR43","doi-asserted-by":"publisher","first-page":"E405","DOI":"10.1055\/s-0033-1344908","volume":"45","author":"S Marjoux","year":"2013","unstructured":"Marjoux S, Pioche M, Benet T, Lanne JS, Roman S, Ponchon T, et al. Fatal mediastinitis following botulinum toxin injection for esophageal spasm. Endoscopy. 2013;45(Suppl 2 UCTN):E405\u20136. https:\/\/doi.org\/10.1055\/s-0033-1344908 .","journal-title":"Endoscopy"},{"issue":"6","key":"212_CR44","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1067\/mge.2001.119256","volume":"54","author":"Martin Storr","year":"2001","unstructured":"Storr M, Allescher HD, R\u00f6sch T, Born P, Weigert N, Classen M. Treatment of symptomatic diffuse esophageal spasm by endoscopic injection of botulinum toxin: a prospective study with long term follow-up. Gastrointest Endosc. 2001;54(6):18A","journal-title":"Gastrointestinal Endoscopy"},{"key":"212_CR45","doi-asserted-by":"publisher","unstructured":"Sloan JA, Mulki R, Sandhu N, Samuel S, Katz PO. Jackhammer esophagus: symptom presentation, associated distal contractile integral, and assessment of bolus transit. J Clin Gastroenterol. 2018. https:\/\/doi.org\/10.1097\/MCG.0000000000001021 .","DOI":"10.1097\/MCG.0000000000001021"},{"issue":"1","key":"212_CR46","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s10620-016-4373-1","volume":"62","author":"MA Khan","year":"2017","unstructured":"Khan MA, Kumbhari V, Ngamruengphong S, Ismail A, Chen YI, Chavez YH, et al. Is POEM the answer for management of spastic esophageal disorders? A systematic review and meta-analysis. Dig Dis Sci. 2017;62(1):35\u201344. https:\/\/doi.org\/10.1007\/s10620-016-4373-1 .","journal-title":"Dig Dis Sci"},{"issue":"2","key":"212_CR47","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1111\/j.1365-2036.2011.04702.x","volume":"34","author":"AC Ford","year":"2011","unstructured":"Ford AC, Suares NC, Talley NJ. Meta-analysis: the epidemiology of noncardiac chest pain in the community. Aliment Pharmacol Ther. 2011;34(2):172\u201380. https:\/\/doi.org\/10.1111\/j.1365-2036.2011.04702.x .","journal-title":"Aliment Pharmacol Ther"},{"issue":"8","key":"212_CR48","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1016\/j.cgh.2013.08.036","volume":"12","author":"E Coss-Adame","year":"2014","unstructured":"Coss-Adame E, Erdogan A, Rao SS. Treatment of esophageal (noncardiac) chest pain: an expert review. Clin Gastroenterol Hepatol. 2014;12(8):1224\u201345. https:\/\/doi.org\/10.1016\/j.cgh.2013.08.036 .","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"212_CR49","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/j.1365-2036.2011.04904.x","volume":"35","author":"T Hershcovici","year":"2012","unstructured":"Hershcovici T, Achem SR, Jha LK, Fass R. Systematic review: the treatment of noncardiac chest pain. Aliment Pharmacol Ther. 2012;35(1):5\u201314. https:\/\/doi.org\/10.1111\/j.1365-2036.2011.04904.x .","journal-title":"Aliment Pharmacol Ther"},{"issue":"7","key":"212_CR50","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1111\/j.1572-0241.2002.05821.x","volume":"97","author":"LS Miller","year":"2002","unstructured":"Miller LS, Pullela SV, Parkman HP, Schiano TD, Cassidy MJ, Cohen S, et al. Treatment of chest pain in patients with noncardiac, nonreflux, nonachalasia spastic esophageal motor disorders using botulinum toxin injection into the gastroesophageal junction. Am J Gastroenterol. 2002;97(7):1640\u20136. https:\/\/doi.org\/10.1111\/j.1572-0241.2002.05821.x .","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"212_CR51","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.amjoto.2016.07.006","volume":"37","author":"AP Marston","year":"2016","unstructured":"Marston AP, Maldonado FJ, Ravi K, Kasperbauer JL, Ekbom DC. Treatment of oropharyngeal dysphagia secondary to idiopathic cricopharyngeal bar: surgical cricopharyngeal muscle myotomy versus dilation. Am J Otolaryngol. 2016;37(6):507\u201312. https:\/\/doi.org\/10.1016\/j.amjoto.2016.07.006 .","journal-title":"Am J Otolaryngol"},{"key":"212_CR52","doi-asserted-by":"publisher","first-page":"CD009968","DOI":"10.1002\/14651858.CD009968.pub2","volume":"5","author":"J Regan","year":"2014","unstructured":"Regan J, Murphy A, Chiang M, McMahon BP, Coughlan T, Walshe M. Botulinum toxin for upper oesophageal sphincter dysfunction in neurological swallowing disorders. Cochrane Database Syst Rev. 2014;5:CD009968. https:\/\/doi.org\/10.1002\/14651858.CD009968.pub2 .","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"212_CR53","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1177\/000348941312200205","volume":"122","author":"EA Kelly","year":"2013","unstructured":"Kelly EA, Koszewski IJ, Jaradeh SS, Merati AL, Blumin JH, Bock JM. Botulinum toxin injection for the treatment of upper esophageal sphincter dysfunction. Ann Otol Rhinol Laryngol. 2013;122(2):100\u20138. https:\/\/doi.org\/10.1177\/000348941312200205 .","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"212_CR54","doi-asserted-by":"publisher","first-page":"e102","DOI":"10.1097\/PHM.0000000000000959","volume":"97","author":"YC Wang","year":"2018","unstructured":"Wang YC, Shyu SG, Wu CH, Wang TG. Ultrasound-guided injection of botulinum toxin for cricopharyngeal dysphagia. Am J Phys Med Rehabil. 2018;97:e102\u20133. https:\/\/doi.org\/10.1097\/PHM.0000000000000959 .","journal-title":"Am J Phys Med Rehabil"},{"key":"212_CR55","doi-asserted-by":"publisher","unstructured":"Ortiz V, Garc\u00eda-Campos M, S\u00e1ez-Gonz\u00e1lez E, del Pozo P, Garrigues V. A concise review of opioid-induced esophageal dysfunction: is this a new clinical entity? Dis Esophagus. 2018. https:\/\/doi.org\/10.1093\/dote\/doy003 .","DOI":"10.1093\/dote\/doy003"},{"issue":"4","key":"212_CR56","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/MOG.0000000000000365","volume":"33","author":"Peter J. Kahrilas","year":"2017","unstructured":"Kahrilas PJ, Pandolfino JE. Treatments for achalasia in 2017: how to choose among them. Curr Opin Gastroenterol. 2017;33(4):270\u20136. https:\/\/doi.org\/10.1097\/MOG.0000000000000365","journal-title":"Current Opinion in Gastroenterology"},{"issue":"4","key":"212_CR57","doi-asserted-by":"publisher","first-page":"e166","DOI":"10.14309\/crj.2016.139","volume":"3","author":"G You","year":"2016","unstructured":"You G, Khan A, Shor J, Forester GP. Rapidly progressive muscle paralysis and acute respiratory failure following endoscopic botulinum toxin injection. ACG Case Rep J. 2016;3(4):e166. https:\/\/doi.org\/10.14309\/crj.2016.139 .","journal-title":"ACG Case Rep J"},{"key":"212_CR58","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1016\/j.cgh.2018.04.026","volume":"16","author":"PJ Kahrilas","year":"2018","unstructured":"Kahrilas PJ, Bredenoord AJ, Carlson DA, Pandolfino JE. Advances in management of esophageal motility disorders. Clin Gastroenterol Hepatol. 2018;16:1692\u2013700. https:\/\/doi.org\/10.1016\/j.cgh.2018.04.026 .","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Current Treatment Options in Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11938-018-0212-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11938-018-0212-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11938-018-0212-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T15:19:52Z","timestamp":1662391192000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11938-018-0212-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,8]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["212"],"URL":"https:\/\/doi.org\/10.1007\/s11938-018-0212-0","relation":{},"ISSN":["1092-8472","1534-309X"],"issn-type":[{"value":"1092-8472","type":"print"},{"value":"1534-309X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,8]]},"assertion":[{"value":"8 November 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"Jessica Sterling declares that she has no conflict of interest. Ron Schey declares that he has no conflict of interest. Zubair Malik declares that he has no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article does not contain any studies with human or animal subjects performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}]}}