{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:32:11Z","timestamp":1791246731934,"version":"4.1.0"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s11999-014-3935-9","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T16:45:27Z","timestamp":1410972327000},"page":"337-347","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Local Gentamicin Delivery From Resorbable Viscous Hydrogels Is Therapeutically Effective"],"prefix":"10.1097","volume":"473","author":[{"given":"Derek","family":"Overstreet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"McLaren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Calara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent","family":"Vernon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"McLemore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-61-20210317","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/00003086-199205000-00037","article-title":"In vitro and in vivo evaluation of antibiotic diffusion from antibiotic-impregnated polymethylmethacrylate beads.","volume":"278","author":"Adams","year":"1992","journal-title":"Clin Orthop Relat Res"},{"key":"R5-61-20210317","first-page":"85","article-title":"Innate and induced resistance mechanisms of bacterial biofilms.","volume":"322","author":"Anderson","year":"2008","journal-title":"Curr Top Microbiol Immunol"},{"key":"R10-61-20210317","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1590\/S1807-59322007000200002","article-title":"Prospective study of the treatment of infected hip arthroplasties with or without the use of an antibiotic-loaded cement spacer.","volume":"62","author":"Cabrita","year":"2007","journal-title":"Clin Sao Paulo Braz"},{"key":"R12-61-20210317","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1128\/JCM.37.6.1771-1776.1999","article-title":"The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms.","volume":"37","author":"Ceri","year":"1999","journal-title":"J Clin Microbiol"},{"key":"R15-61-20210317","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/S0022-3565(25)30140-0","article-title":"Effect of gentamicin on renal function in the rat.","volume":"193","author":"Cohen","year":"1975","journal-title":"J Pharmacol Exp Ther"},{"key":"R19-61-20210317","first-page":"3854S","article-title":"Effect of molecular size of pegylated peptide on the pharmacokinetics and tumor targeting in lymphoma-bearing mice.","volume":"9","author":"DeNardo","year":"2003","journal-title":"Clin Cancer Res"},{"key":"R28-61-20210317","first-page":"202","article-title":"The physiology and collective recalcitrance of microbial biofilm communities.","volume":"46","author":"Gilbert","year":"2002","journal-title":"Adv Microb Physiol"},{"key":"R29-61-20210317","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.1128\/IAI.63.9.3373-3380.1995","article-title":"Role of the accessory gene regulator (AGR) in pathogenesis of staphylococcal osteomyelitis.","volume":"63","author":"Gillaspy","year":"1995","journal-title":"Infect Immun"},{"key":"R36-61-20210317","first-page":"107","article-title":"Multidrug tolerance of biofilms and persister cells.","volume":"322","author":"Lewis","year":"2008","journal-title":"Curr Top Microbiol Immunol"},{"key":"R43-61-20210317","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1128\/AAC.43.5.1003","article-title":"Aminoglycosides: nephrotoxicity.","volume":"43","author":"Mingeot-Leclercq","year":"1999","journal-title":"Antimicrob Agents Chemother"},{"key":"R44-61-20210317","first-page":"96","article-title":"Effect of gentamicin on shear and interface strengths of bone cement.","volume":"141","author":"Moran","year":"1979","journal-title":"Clin Orthop Relat Res"},{"key":"R49-61-20210317","first-page":"86","article-title":"Biofilm bacteria: formation and comparative susceptibility to antibiotics.","volume":"66","author":"Olson","year":"2002","journal-title":"Can J Vet Res"},{"key":"R57-61-20210317","first-page":"99","article-title":"Correlation of histology with culture to more accurately determine experimental osteomyelitis.","volume":"18598-","author":"Skinner","year":"1994","journal-title":"Orthop Trans"},{"key":"R62-61-20210317","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/S0142-9612(00)00313-6","article-title":"Staphylococcus aureus biofilm formation on different gentamicin-loaded polymethylmethacrylate bone cements.","volume":"22","author":"VV Van de Belt","year":"2001","journal-title":"Biomaterials"}],"container-title":["Clinical Orthopaedics & Related Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1007\/s11999-014-3935-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T17:55:34Z","timestamp":1746381334000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003086-201501000-00061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1007\/s11999-014-3935-9","relation":{},"ISSN":["0009-921X"],"issn-type":[{"value":"0009-921X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}