{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:14:41Z","timestamp":1780103681142,"version":"3.54.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T00:00:00Z","timestamp":1369785600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1007\/s12010-013-0304-1","type":"journal-article","created":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T01:06:55Z","timestamp":1369703215000},"page":"1637-1648","source":"Crossref","is-referenced-by-count":9,"title":["The Effect of Albumin Fusion Patterns on the Production and Bioactivity of the Somatostatin-14 Fusion Protein in Pichia pastoris"],"prefix":"10.1007","volume":"170","author":[{"given":"Yuedi","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runlin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,5,29]]},"reference":[{"key":"304_CR1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1126\/science.179.4068.77","volume":"179","author":"P Brazeau","year":"1973","unstructured":"Brazeau, P., Vale, W., Burgus, R., Ling, N., Butcher, M., Rivier, J., et al. (1973). Science, 179, 77\u201379.","journal-title":"Science"},{"key":"304_CR2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/frne.1999.0183","volume":"20","author":"YC Patel","year":"1999","unstructured":"Patel, Y. C. (1999). Frontiers in Neuroendocrinology, 20, 157\u2013198.","journal-title":"Frontiers in Neuroendocrinology"},{"key":"304_CR3","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.mce.2007.10.015","volume":"286","author":"LJ Hofland","year":"2008","unstructured":"Hofland, L. J. (2008). Molecular and Cellular Endocrinology, 286, 199\u2013205.","journal-title":"Molecular and Cellular Endocrinology"},{"key":"304_CR4","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.mce.2008.02.002","volume":"286","author":"S Pyronnet","year":"2008","unstructured":"Pyronnet, S., Bousquet, C., Najib, S., Azar, R., Laklai, H., & Susini, C. (2008). Molecular and Cellular Endocrinology, 286, 230\u2013237.","journal-title":"Molecular and Cellular Endocrinology"},{"key":"304_CR5","first-page":"370","volume":"33","author":"K Thermos","year":"1988","unstructured":"Thermos, K., & Reisine, T. (1988). Molecular Pharmacology, 33, 370\u2013377.","journal-title":"Molecular Pharmacology"},{"key":"304_CR6","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1111\/j.1471-4159.2004.02402.x","volume":"89","author":"G Olias","year":"2004","unstructured":"Olias, G., Viollet, C., Kusserow, H., Epelbaum, J., & Meyerhof, W. (2004). Journal of Neurochemistry, 89, 1057\u20131091.","journal-title":"Journal of Neurochemistry"},{"key":"304_CR7","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.mce.2007.09.009","volume":"286","author":"A Schonbrunn","year":"2008","unstructured":"Schonbrunn, A. (2008). Molecular and Cellular Endocrinology, 286, 35\u201339.","journal-title":"Molecular and Cellular Endocrinology"},{"key":"304_CR8","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1210\/endo-112-1-220","volume":"112","author":"YC Patel","year":"1983","unstructured":"Patel, Y. C., & Wheatley, T. (1983). Endocrinology, 112, 220\u2013225.","journal-title":"Endocrinology"},{"key":"304_CR9","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1210\/jc.2008-1919","volume":"94","author":"S Lesche","year":"2009","unstructured":"Lesche, S., Lehmann, D., Nagel, F., Schmid, H. A., & Schulz, S. (2009). Journal of Clinical Endocrinology and Metabolism, 94, 654\u2013661.","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"304_CR10","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1365-2265.2005.02322.x","volume":"63","author":"J Hoek van der","year":"2005","unstructured":"van der Hoek, J., van der Lelij, A. J., Feelders, R. A., de Herder, W. W., Uitterlinden, P., Poon, K. W., et al. (2005). Clinical Endocrinology, 63, 176\u2013184.","journal-title":"Clinical Endocrinology"},{"key":"304_CR11","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s10620-006-3113-3","volume":"51","author":"V Olgac","year":"2006","unstructured":"Olgac, V., Erbil, Y., Barbaros, U., Oztezcan, S., Giris, M., Kaya, H., et al. (2006). Digestive Diseases and Sciences, 51, 227\u2013232.","journal-title":"Digestive Diseases and Sciences"},{"key":"304_CR12","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.pep.2008.04.012","volume":"61","author":"WF Dou","year":"2008","unstructured":"Dou, W. F., Lei, J. Y., Zhang, L. F., Xu, Z. H., Chen, Y., & Jin, J. (2008). Protein Expression and Purification, 61, 45\u201349.","journal-title":"Protein Expression and Purification"},{"key":"304_CR13","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1023\/A:1020917732218","volume":"19","author":"W Halpern","year":"2002","unstructured":"Halpern, W., Riccobene, T. A., Agostini, H., Baker, K., Stolow, D., Gu, M. L., et al. (2002). Pharmaceutical Research, 19, 1720\u20131729.","journal-title":"Pharmaceutical Research"},{"key":"304_CR14","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1124\/jpet.102.037002","volume":"303","author":"BL Osborn","year":"2002","unstructured":"Osborn, B. L., Olsen, H. S., Nardelli, B., Murray, J. H., Zhou, J. X., Garcia, A., et al. (2002). Journal of Pharmacol and Experimental Therapeutics, 303, 540\u2013548.","journal-title":"Journal of Pharmacol and Experimental Therapeutics"},{"key":"304_CR15","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1271\/bbb.80742","volume":"73","author":"Z Gao","year":"2009","unstructured":"Gao, Z., Bai, G., Chen, J., Zhang, Q., Pan, P., Bai, F., et al. (2009). Bioscience, Biotechnology, and Biochemistry, 73, 688\u2013694.","journal-title":"Bioscience, Biotechnology, and Biochemistry"},{"key":"304_CR16","doi-asserted-by":"crossref","unstructured":"Zhan, J., Chen, Y., Yuan, H. Y., Li, H. and Lu, H. Biotechnology Letters, 34, 417\u2013423.","DOI":"10.1007\/s10529-011-0793-3"},{"key":"304_CR17","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jbiotec.2007.04.016","volume":"131","author":"HL Zhao","year":"2007","unstructured":"Zhao, H. L., Xue, C., Wang, Y., Li, X. Y., Xiong, X. H., Yao, X. Q., et al. (2007). Journal of Biotechnology, 131, 245\u2013252.","journal-title":"Journal of Biotechnology"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-013-0304-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12010-013-0304-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-013-0304-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T01:23:38Z","timestamp":1559438618000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12010-013-0304-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,29]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["304"],"URL":"https:\/\/doi.org\/10.1007\/s12010-013-0304-1","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,29]]}}}