{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T02:33:34Z","timestamp":1773369214686,"version":"3.50.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2015,1,11]],"date-time":"2015-01-11T00:00:00Z","timestamp":1420934400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1007\/s12010-014-1472-3","type":"journal-article","created":{"date-parts":[[2015,1,10]],"date-time":"2015-01-10T09:21:48Z","timestamp":1420881708000},"page":"2934-2949","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Enhanced Production of Nargenicin A1 and Generation of Novel Glycosylated Derivatives"],"prefix":"10.1007","volume":"175","author":[{"given":"Dipesh","family":"Dhakal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuoi Thi","family":"Le","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh Prasad","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit Kumar","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RitBahadur","family":"Gurung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prakash","family":"Parajuli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anaya Raj","family":"Pokhrel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Cheol","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Kyung","family":"Sohng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,1,11]]},"reference":[{"key":"1472_CR1","doi-asserted-by":"crossref","first-page":"4203","DOI":"10.1021\/ja00532a036","volume":"102","author":"WD Celmer","year":"1980","unstructured":"Celmer, W. D., Chmurny, G. N., Moppett, C. E., Ware, R. S., Watts, P. C., & Whipple, E. B. (1980). Structure of natural antibiotic CP-47,444. Journal of the American Chemical Society, 102, 4203\u20134209.","journal-title":"Journal of the American Chemical Society"},{"key":"1472_CR2","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1007\/s12272-001-2115-0","volume":"31","author":"JK Sohng","year":"2008","unstructured":"Sohng, J. K., Yamaguchi, T., Seong, C. N., Baik, K. S., Park, S. C., Lee, H., Jang, J., Simkhada, J., & Yoo, J. C. (2008). Production, isolation and biological activity of nargenicin from Nocardia sp. CS682. Archives of Pharmacal Research, 31, 1339\u20131345.","journal-title":"Archives of Pharmacal Research"},{"key":"1472_CR3","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1016\/j.bcp.2009.03.004","volume":"77","author":"SH Kim","year":"2009","unstructured":"Kim, S. H., Yoo, J. C., & Kim, T. S. (2009). Nargenicin enhances 1,25-dihydroxyvitamin D3- and all-trans retinoic acid-induced leukemia cell differentiation via PKC\u03b2I\/MAPK pathways. Biochemical Pharmacology, 77, 1694\u20131701.","journal-title":"Biochemical Pharmacology"},{"key":"1472_CR4","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1097\/WNR.0b013e32832d2239","volume":"20","author":"JC Yoo","year":"2009","unstructured":"Yoo, J. C., Cho, H. S., Park, E., Park, J. A., Kim, S., Kim, D. K., Kim, C. S., & Chun, H. S. (2009). Nargenicin attenuates lipopolysaccharide-induced inflammatory responses in BV-2 cells. Neuroreport, 20, 1007\u20131012.","journal-title":"Neuroreport"},{"key":"1472_CR5","doi-asserted-by":"crossref","first-page":"443","DOI":"10.2165\/00003495-200161040-00003","volume":"61","author":"GG Zhanel","year":"2001","unstructured":"Zhanel, G. G., Dueck, M., Hoban, D. J., Vercaigne, L. M., Embil, J. M., Gin, A. S., & Karlowsky, J. A. (2001). Review of macrolides and ketolides. Drugs, 61, 443\u2013498.","journal-title":"Drugs"},{"key":"1472_CR6","unstructured":"Painter, R. E., Goetz, M., Gill, C., Allocco, J., Nare,\u00a0B., Powles, M., & Young, K. (2011), Presentation abstract, Merck Res. Lab., Rahway, USA."},{"key":"1472_CR7","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ymben.2008.07.001","volume":"10","author":"C Olano","year":"2008","unstructured":"Olano, C., Lomb\u00f3, F., M\u00e9ndez, C., & Salas, J. A. (2008). Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering. Metabolic Engineering, 10, 281\u2013292.","journal-title":"Metabolic Engineering"},{"key":"1472_CR8","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1751-7915.2010.00231.x","volume":"4","author":"C Olano","year":"2011","unstructured":"Olano, C., M\u00e9ndez, C., & Salas, J. A. (2011). Molecular insights on the biosynthesis of antitumour compounds by actinomycetes. Microbial Biotechnology, 4, 144\u2013164.","journal-title":"Microbial Biotechnology"},{"key":"1472_CR9","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2165\/00003088-198916040-00001","volume":"16","author":"P Periti","year":"1989","unstructured":"Periti, P., Mazzei, T., Mini, E., & Novelli, A. (1989). Clinical pharmacokinetic properties of the macrolide antibiotics. Clinical Pharmacokinetics, 16, 193\u2013214.","journal-title":"Clinical Pharmacokinetics"},{"key":"1472_CR10","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.2741\/4050","volume":"17","author":"M Gorska","year":"2011","unstructured":"Gorska, M., Popowska, U., Sielicka-Dudzin, A., Kuban-Jankowska, A., Sawczuk, W., Knap, N., Cicero, G., & Wozniak, F. (2011). Geldanamycin and its derivatives as Hsp90 inhibitors. Frontiers in Bioscience (Landmark edition), 17, 2269\u20132277.","journal-title":"Frontiers in Bioscience (Landmark edition)"},{"key":"1472_CR11","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/bit.22782","volume":"107","author":"D Simkhada","year":"2010","unstructured":"Simkhada, D., Lee, H. C., & Sohng, J. K. (2010). Genetic engineering approach for the production of rhamnosyl and allosyl flavonoids from Escherichia coli. Biotechnology and Bioengineering, 107, 154\u2013162.","journal-title":"Biotechnology and Bioengineering"},{"key":"1472_CR12","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1039\/c2np20039b","volume":"29","author":"S Singh","year":"2012","unstructured":"Singh, S., Phillips, G. N., Jr., & Thorson, J. S. (2012). The structural biology of enzymes involved in natural product glycosylation. Natural Product Reports, 29, 1201\u20131237.","journal-title":"Natural Product Reports"},{"key":"1472_CR13","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.2174\/0929867013372193","volume":"8","author":"V Kren","year":"2001","unstructured":"Kren, V., & Mart\u00ednkov\u00e1, L. (2001). Glycosides in medicine: \u201cthe role of glycosidic residue in biological activity\u201d. Current Medicinal Chemistry, 8, 1303\u20131328.","journal-title":"Current Medicinal Chemistry"},{"key":"1472_CR14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1039\/np9971400099","volume":"14","author":"AC Weymouth-Wilson","year":"1997","unstructured":"Weymouth-Wilson, A. C. (1997). The role of carbohydrates in biologically active natural products. Natural Product Reports, 14, 99\u2013110.","journal-title":"Natural Product Reports"},{"key":"1472_CR15","doi-asserted-by":"crossref","first-page":"6833","DOI":"10.1128\/AEM.02057-13","volume":"79","author":"RP Pandey","year":"2013","unstructured":"Pandey, R. P., Parajuli, P., Koirala, N., Park, J. W., & Sohng, J. K. (2013). Probing 3-hydroxyflavone for in vitro glycorandomization of flavonols by YjiC. Applied and Environmental Microbiology, 79, 6833\u20136838.","journal-title":"Applied and Environmental Microbiology"},{"key":"1472_CR16","doi-asserted-by":"crossref","first-page":"10786","DOI":"10.1002\/chem.201103069","volume":"18","author":"T Desmet","year":"2012","unstructured":"Desmet, T., Soetaert, W., Bojarov\u00e1, P., K\u0159en, V., Dijkhuizen, L., Eastwick-Field, V., & Schiller, A. (2012). Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts. Chemistry--A European Journal, 18, 10786\u201310801.","journal-title":"Chemistry--A European Journal"},{"key":"1472_CR17","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1002\/bit.24919","volume":"110","author":"S Malla","year":"2013","unstructured":"Malla, S., Pandey, R. P., Kim, B. G., & Sohng, J. K. (2013). Regiospecific modifications of naringenin for astragalin production in Escherichia coli. Biotechnology and Bioengineering, 110, 2525\u20132535.","journal-title":"Biotechnology and Bioengineering"},{"key":"1472_CR18","doi-asserted-by":"crossref","unstructured":"Lee, H. C., Lee, S. D., Sohng, J. K., & Liou, K. (2004). One-pot enzymatic synthesis of UDP-D-glucose from UMP and glucose-1-phosphate using an ATP regeneration system. Journal of Biochemistry and Molecular Biology, 37, 503\u2013506.","DOI":"10.5483\/BMBRep.2004.37.4.503"},{"key":"1472_CR19","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.molcatb.2009.11.008","volume":"62","author":"YH Yang","year":"2010","unstructured":"Yang, Y. H., Kang, Y. B., Kim, D. H., Lee, T. H., Park, S. H., Lee, K., Yoo, D., Liou, K. K., Lee, H. C., Sohng, J. K., & Kim, B. G. (2010). One-pot enzymatic synthesis of deoxy-thymidine-diphosphate (TDP)-2-deoxy-\u03b1-D-glucose using phosphomannomutase. Journal of Molecular Catalysis B: Enzymatic, 62, 282\u2013287.","journal-title":"Journal of Molecular Catalysis B: Enzymatic"},{"key":"1472_CR20","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1016\/j.febslet.2007.04.074","volume":"581","author":"S Masada","year":"2007","unstructured":"Masada, S., Kawase, Y., Nagatoshi, M., Oguchi, Y., Terasaka, K., & Mizukami, H. (2007). An efficient chemoenzymatic production of small molecule glucosides with in situ UDP-glucose recycling. FEBS Letters, 581, 2562\u20132566.","journal-title":"FEBS Letters"},{"key":"1472_CR21","doi-asserted-by":"crossref","first-page":"4344","DOI":"10.1016\/j.febslet.2012.10.045","volume":"586","author":"K Terasaka","year":"2012","unstructured":"Terasaka, K., Mizutani, Y., Nagatsu, A., & Mizukami, H. (2012). In situ UDP-glucose regeneration unravels diverse functions of plant secondary product glycosyltransferases. FEBS Letters, 586, 4344\u20134350.","journal-title":"FEBS Letters"},{"key":"1472_CR22","doi-asserted-by":"crossref","first-page":"8527","DOI":"10.1007\/s00253-014-5947-5","volume":"98","author":"LT Tuoi","year":"2014","unstructured":"Tuoi, L. T., Pandey, R. P., Gurung, R. B., Dhakal, D., & Sohng, J. K. (2014). Efficient enzymatic systems for synthesis of novel \u03b1-mangostin glycosides exhibiting antibacterial activity against Gram-positive bacteria. Applied Microbiology and Biotechnology, 98, 8527\u20138538.","journal-title":"Applied Microbiology and Biotechnology"},{"key":"1472_CR23","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.4014\/jmb.1202.02027","volume":"22","author":"D Koju","year":"2012","unstructured":"Koju, D., Dhakal, D., & Sohng, J. K. (2012). Effect of different biosynthetic precursors on the production of nargenicin A1 from metabolically engineered Nocardia sp. CS682. Journal of Microbiology and Biotechnology, 22, 1127\u20131132.","journal-title":"Journal of Microbiology and Biotechnology"},{"key":"1472_CR24","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1039\/b605245m","volume":"23","author":"CT Walsh","year":"2006","unstructured":"Walsh, C. T., Garneau-Tsodikova, S., & Howard-Jones, A. R. (2006). Biological formation of pyrroles: nature's logic and enzymatic machinery. Natural Product Reports, 23, 517\u2013531.","journal-title":"Natural Product Reports"},{"key":"1472_CR25","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s00253-011-3567-x","volume":"93","author":"S Maharjan","year":"2012","unstructured":"Maharjan, S., Aryal, N., Bhattarai, S., Koju, D., Lamichhane, J., & Sohng, J. K. (2012). Biosynthesis of the nargenicin A1 pyrrole moiety from Nocardia sp. CS682. Applied Microbiology and Biotechnology, 93, 687\u2013696.","journal-title":"Applied Microbiology and Biotechnology"},{"key":"1472_CR26","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72, 248\u2013254.","journal-title":"Analytical Biochemistry"},{"key":"1472_CR27","doi-asserted-by":"crossref","unstructured":"Chaudhary, A. K., Dhakal, D., &Sohng, J. K. (2013). An insight into the \u201c-omics\u201d based engineering of streptomycetes for secondary metabolite overproduction. BioMedResearch International, 2013, 968518.","DOI":"10.1155\/2013\/968518"},{"key":"1472_CR28","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.drudis.2008.08.004","volume":"14","author":"SY Lee","year":"2009","unstructured":"Lee, S. Y., Kim, H. U., Park, J. H., Park, J. M., & Kim, T. Y. (2009). Metabolic engineering of microorganisms: general strategies and drug production. Drug Discovery Today, 14, 78\u201388.","journal-title":"Drug Discovery Today"},{"key":"1472_CR29","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s12010-011-9470-1","volume":"166","author":"S Maharjan","year":"2012","unstructured":"Maharjan, S., Koju, D., Lee, H. C., Yoo, J. C., & Sohng, J. K. (2012). Metabolic engineering of Nocardia sp. CS682 for enhanced production of nargenicin A1. Applied Biochemistry and Biotechnology, 166, 805\u2013817.","journal-title":"Applied Biochemistry and Biotechnology"},{"key":"1472_CR30","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s10295-013-1374-3","volume":"41","author":"Y Gao","year":"2014","unstructured":"Gao, Y., Fan, Y., Nambou, K., Wei, L., Liu, Z., Imanaka, T., & Hua, Q. (2014). Enhancement of ansamitocin P-3 production in Actinosynnemapretiosum by a synergistic effect of glycerol and glucose. Journal of Industrial Microbiology & Biotechnology, 41, 143\u2013152.","journal-title":"Journal of Industrial Microbiology & Biotechnology"},{"key":"1472_CR31","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.micres.2011.02.007","volume":"167","author":"S Paudel","year":"2011","unstructured":"Paudel, S., Lee, H. C., Kim, B. S., & Sohng, J. K. (2011). Enhancement of pradimicin production in Actinomadurahibisca P157-2 by metabolic engineering. Microbiological Research, 167, 32\u201339.","journal-title":"Microbiological Research"},{"key":"1472_CR32","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1007\/s10529-008-9735-0","volume":"30","author":"S Maharjan","year":"2008","unstructured":"Maharjan, S., Oh, T. J., Lee, H. C., & Sohng, J. K. (2008). Heterologous expression of metK1-sp and afsR-sp in Streptomyces venezuelae for the production of pikromycin. Biotechnology Letters, 30, 1621\u20131626.","journal-title":"Biotechnology Letters"},{"key":"1472_CR33","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4014\/jmb.1308.08063","volume":"24","author":"AK Jha","year":"2014","unstructured":"Jha, A. K., Lamichhane, J., & Sohng, J. K. (2014). Enhancement of herboxidiene production in Streptomyces chromofuscus ATCC 49982. Journal of Microbiology and Biotechnology, 24, 52\u201358.","journal-title":"Journal of Microbiology and Biotechnology"},{"key":"1472_CR34","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0076-6879(09)04621-7","volume":"459","author":"J White-Phillip","year":"2009","unstructured":"White-Phillip, J., Thibodeaux, C. J., & Liu, H. W. (2009). Enzymatic synthesis of TDP-deoxysugars. Methods in Enzymology, 459, 521\u2013544.","journal-title":"Methods in Enzymology"},{"key":"1472_CR35","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1039\/c1np00045d","volume":"28","author":"RW Gantt","year":"2011","unstructured":"Gantt, R. W., Peltier-Pain, P., & Thorson, J. S. (2011). Enzymatic methods for glyco (diversification\/randomization) of drugs and small molecules. Natural Product Reports, 28, 1811\u20131853.","journal-title":"Natural Product Reports"},{"key":"1472_CR36","doi-asserted-by":"crossref","first-page":"371","DOI":"10.7164\/antibiotics.44.371","volume":"44","author":"T Furumoto","year":"1991","unstructured":"Furumoto, T., Yoshika, T., Kamata, K., Kameda, Y., & MatsuiI, K. (1991). Enzymic synthesis of valienamine glucosides and their antibiotic activity. Journal of Antibiotics, 44, 371\u2013373.","journal-title":"Journal of Antibiotics"},{"key":"1472_CR37","unstructured":"Glycosylated aminocoumarins and methods of preparing and uses of same. Available from http:\/\/www.google.com\/patents\/EP2627661A1?cl=en . Accessed 30 Jul 2014"},{"key":"1472_CR38","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1093\/carcin\/17.11.2385","volume":"17","author":"G Williamson","year":"1996","unstructured":"Williamson, G., Plumb, G. W., Uda, Y., Price, K. R., & Rhodes, M. J. (1996). Dietary quercetin glycosides: antioxidant activity and induction of the anticarcinogenic phase II marker enzyme quinone reductase in Hepalclc7 cells. Carcinogenesis, 17, 2385\u20132387.","journal-title":"Carcinogenesis"},{"key":"1472_CR39","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0891-5849(03)00325-3","volume":"35","author":"KI Priyadarsini","year":"2003","unstructured":"Priyadarsini, K. I., Maity, D. K., Naik, G. H., Kumar, M. S., Unnikrishnan, M. K., Satav, J. G., & Mohan, H. (2003). Role of phenolic OH and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin. Free Radical Biology and Medicine, 35, 475\u2013484.","journal-title":"Free Radical Biology and Medicine"},{"key":"1472_CR40","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.carres.2014.03.011","volume":"393","author":"RP Pandey","year":"2014","unstructured":"Pandey, R. P., Gurung, R. B., Parajuli, P., Koirala, N., Tuoi, L. T., & Sohng, J. K. (2014). Assessing acceptor substrate promiscuity of YjiC-mediated glycosylation toward flavonoids. Carbohydrate Research, 393, 26\u201331.","journal-title":"Carbohydrate Research"},{"key":"1472_CR41","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s10059-013-0164-0","volume":"36","author":"RB Gurung","year":"2013","unstructured":"Gurung, R. B., Kim, E. H., Oh, T. J., & Sohng, J. K. (2013). Enzymatic synthesis of apigenin glucosides by glucosyltransferase (YjiC) from Bacillus licheniformis DSM 13. Molecules and Cells, 36, 355\u2013361.","journal-title":"Molecules and Cells"},{"key":"1472_CR42","doi-asserted-by":"crossref","first-page":"7680","DOI":"10.1128\/AEM.02004-12","volume":"78","author":"CZ Wu","year":"2012","unstructured":"Wu, C. Z., Jang, J. H., Woo, M., Ahn, J. S., Kim, J. S., & Hong, Y. S. (2012). Enzymatic glycosylation of nonbenzoquinone geldanamycin analogs via Bacillus UDP-glycosyltransferase. Applied and Environmental Microbiology, 78, 7680\u20137686.","journal-title":"Applied and Environmental Microbiology"},{"key":"1472_CR43","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13568-014-0031-1","volume":"4","author":"P Parajuli","year":"2014","unstructured":"Parajuli, P., Pandey, R. P., Koirala, N., Yoon, Y. J., Kim, B. G., & Sohng, J. K. (2014). Enzymatic synthesis of epothilone A glycosides. AMB Express, 4, 31.","journal-title":"AMB Express"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-014-1472-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12010-014-1472-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-014-1472-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T14:19:52Z","timestamp":1566224392000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12010-014-1472-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,11]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["1472"],"URL":"https:\/\/doi.org\/10.1007\/s12010-014-1472-3","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,11]]}}}