{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T19:32:07Z","timestamp":1784835127559,"version":"3.55.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100007787","name":"National Research Centre","doi-asserted-by":"crossref","award":["(internal project no: 11010130).)"],"award-info":[{"award-number":["(internal project no: 11010130).)"]}],"id":[{"id":"10.13039\/100007787","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1007\/s12010-020-03230-z","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T03:02:46Z","timestamp":1579575766000},"page":"1127-1139","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Homocysteine and Asymmetrical Dimethylarginine in Diabetic Rats Treated with Docosahexaenoic Acid\u2013Loaded Zinc Oxide Nanoparticles"],"prefix":"10.1007","volume":"191","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1862-0385","authenticated-orcid":false,"given":"Jihan","family":"Hussein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehrez","family":"El-Naggar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehsan","family":"Badawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabila","family":"El-laithy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha","family":"El-Waseef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanan","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Abdel-Latif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,21]]},"reference":[{"key":"3230_CR1","doi-asserted-by":"crossref","first-page":"11S","DOI":"10.1016\/j.amjmed.2003.10.016","volume":"116","author":"RW Nesto","year":"2004","unstructured":"Nesto, R. W. (2004). Correlation between cardiovascular disease and diabetes mellitus: current concepts. The American Journal of Medicine, 116, 11S\u201322S.","journal-title":"The American Journal of Medicine"},{"issue":"12","key":"3230_CR2","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1016\/j.bbadis.2013.08.006","volume":"1832","author":"CM Sena","year":"2013","unstructured":"Sena, C. M., Pereira, A. M., & Sei\u00e7a, R. (2013). Endothelial dysfunction - a major mediator of diabetic vascular disease. Biochimica et Biophysica Acta, 1832(12), 2216\u20132231.","journal-title":"Biochimica et Biophysica Acta"},{"issue":"5","key":"3230_CR3","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.jstrokecerebrovasdis.2010.12.006","volume":"20","author":"H Hagiwara","year":"2011","unstructured":"Hagiwara, H., Nishiyama, Y., & Katayama, Y. (2011). Effects of eicosapentaenoic acid on asymmetric dimethylarginine in patients in the chronic phase of cerebral infarction: a preliminary study. Journal of Stroke and Cerebrovascular Diseases, 20(5), 474\u2013478.","journal-title":"Journal of Stroke and Cerebrovascular Diseases"},{"key":"3230_CR4","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.atherosclerosis.2010.11.014","volume":"214","author":"C Korandjia","year":"2011","unstructured":"Korandjia, C., Zeller, M., & Guillanda, J. C. (2011). Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome. Atherosclerosis, 214, 310\u2013315.","journal-title":"Atherosclerosis"},{"key":"3230_CR5","first-page":"217","volume":"19","author":"J Selhub","year":"1999","unstructured":"Selhub, J. (1999). Homocysteine metabolism. Annual Review of Medicine, 19, 217\u2013246.","journal-title":"Annual Review of Medicine"},{"issue":"3","key":"3230_CR6","doi-asserted-by":"crossref","first-page":"808","DOI":"10.3945\/ajcn.2009.28374","volume":"91","author":"A Stirban","year":"2010","unstructured":"Stirban, A., Nandrean, S., Gotting, C., Tamler, R., Pop, A., Negrean, M., et al. (2010). Effects of n-3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus. The American Journal of Clinical Nutrition, 91(3), 808\u2013813.","journal-title":"The American Journal of Clinical Nutrition"},{"issue":"3","key":"3230_CR7","first-page":"114","volume":"4","author":"V Cavieres","year":"2014","unstructured":"Cavieres, V., Valdes, K., Moreno, B., Moore-Carrasco, R., & Gonzalez, D. R. (2014). Vascular hypercontractility and endothelial dysfunction before development of atherosclerosis in moderate dyslipidemia: role for nitric oxide and interleukin-6. American Journal of Cardiovascular Disease, 4(3), 114\u2013122.","journal-title":"American Journal of Cardiovascular Disease"},{"issue":"2","key":"3230_CR8","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.3390\/ijms15022015","volume":"15","author":"A Alkaladi","year":"2014","unstructured":"Alkaladi, A., Abdelazim, A. M., & Afifi, M. (2014). Antidiabetic activity of zinc oxide and silver nanoparticles on streptozotocin-induced diabetic rats. International Journal of Molecular Sciences, 15(2), 2015\u20132023.","journal-title":"International Journal of Molecular Sciences"},{"issue":"6","key":"3230_CR9","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1002\/jcb.20796","volume":"97","author":"TC Yih","year":"2006","unstructured":"Yih, T. C., & Al-Fandi, M. (2006). Engineered nanoparticles as precise drug delivery system. Journal of Cellular Biochemistry, 97(6), 1184\u20131190.","journal-title":"Journal of Cellular Biochemistry"},{"issue":"24","key":"3230_CR10","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1002\/smll.200901048","volume":"5","author":"SM Hirst","year":"2009","unstructured":"Hirst, S. M., Karakoti, A. S., Tyle, R. R. D., Sriranganathan, N., Seal, S., & Reilly, C. M. (2009). Anti-inflammatory properties of cerium oxide nanoparticles. Small, 5(24), 2848\u20132856.","journal-title":"Small"},{"key":"3230_CR11","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.ijbiomac.2017.09.056","volume":"107","author":"J Hussein","year":"2018","unstructured":"Hussein, J., El-Bannaa, M., Abdel Razikb, T., & El-Naggar, M. E. (2018a). Biocompatible zinc oxide nanocrystals stabilized via hydroxyethyl cellulose for mitigation of diabetic complications. International Journal of Biological Macromolecules, 107, 748\u2013754.","journal-title":"International Journal of Biological Macromolecules"},{"key":"3230_CR12","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.colsurfb.2018.05.058","volume":"170","author":"J Hussein","year":"2018","unstructured":"Hussein, J., El-Naggar, M. E., Abdel Latif, Y., Medhat, D., El Bana, M., Refaat, E., & Morsy, S. (2018b). Solvent-free and one-pot synthesis of silver and zinc oxide nanoparticles: activity toward cell membrane component and insulin signaling pathway in experimental diabetes. Colloids and Surfaces B: Biointerfaces, 170, 76\u201384.","journal-title":"Colloids and Surfaces B: Biointerfaces"},{"key":"3230_CR13","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","volume":"28","author":"DR Mathews","year":"1985","unstructured":"Mathews, D. R., Hoker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985). Homeostasis model assessment: insulin resistance and \u03b2-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28, 412\u2013419.","journal-title":"Diabetologia"},{"issue":"4","key":"3230_CR14","doi-asserted-by":"crossref","first-page":"629","DOI":"10.2337\/dc08-1913","volume":"32","author":"Q Sun","year":"2009","unstructured":"Sun, Q., van Dam, R. M., Willett, W. C., & Hu, F. B. (2009). Prospective study of zinc intake and risk of type 2 diabetes in women. Diabetes Care, 32(4), 629\u2013634.","journal-title":"Diabetes Care"},{"key":"3230_CR15","first-page":"949","volume":"12","author":"S Uchiyama","year":"2003","unstructured":"Uchiyama, S., & Yamaguchi, M. (2003). Alteration in serum and bone component findings induced in streptozotocin-diabetic rats is restored by zinc acexamate. International Journal of Molecular Medicine, 12, 949\u2013954.","journal-title":"International Journal of Molecular Medicine"},{"key":"3230_CR16","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.ijbiomac.2019.08.201","volume":"140","author":"J Hussein","year":"2019","unstructured":"Hussein, J., Attia, M. F., El Bana, M., El-Daly, S. M., Mohamed, N., El-Khayat, Z., & El-Naggar, M. (2019a). Solid state synthesis of docosahexaenoic acid-loaded zinc oxide nanoparticles as a potential antidiabetic agent in rats. International Journal of Biological Macromolecules, 140, 1305\u20131314.","journal-title":"International Journal of Biological Macromolecules"},{"key":"3230_CR17","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1177\/000456326900600108","volume":"6","author":"P Trinder","year":"1969","unstructured":"Trinder, P. (1969). Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Annals of Clinical Biochemistry, 6, 24\u201327.","journal-title":"Annals of Clinical Biochemistry"},{"key":"3230_CR18","first-page":"119","volume-title":"Diabetes mellitus: theory and practice","author":"R Yalow","year":"1983","unstructured":"Yalow, R., & Bauman, W. A. (1983). Insulin in health and disease. In M. Ellenberg & H. Rifkin (Eds.), Diabetes mellitus: theory and practice (pp. 119\u2013150). New York: Excerpta Medica."},{"key":"3230_CR19","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1093\/clinchem\/41.6.892","volume":"41","author":"H Moshage","year":"1995","unstructured":"Moshage, H., Kok, B., & Huizenga, J. R. (1995). Nitrite and nitrate determination in plasma: a critical evaluation. Clinical Chemistry, 41, 892\u2013896.","journal-title":"Clinical Chemistry"},{"issue":"2","key":"3230_CR20","first-page":"146","volume":"5","author":"Z El-Khayat","year":"2013","unstructured":"El-Khayat, Z., Abo El-Matty, D., Rasheed, W., Hussein, J., Shaker, O., & Raafat, J. (2013). Role of cell membrane fatty acids in insulin sensitivity in diabetic rats treated with flaxseed oil. International Journal of Pharmacy and Pharmaceutical Sciences, 5(2), 146\u2013151.","journal-title":"International Journal of Pharmacy and Pharmaceutical Sciences"},{"issue":"2","key":"3230_CR21","first-page":"196","volume":"6","author":"J Hussein","year":"2014","unstructured":"Hussein, J., El-Khayat, Z., Morsy, S., Oraby, F., & Singer, G. (2014). The effect of fish oil on oxidant\/antioxidant status in diabetic rats through the reduction of arachidonic acid in the cell membrane. International Journal of Pharmacy and Pharmaceutical Sciences, 6(2), 196\u2013199.","journal-title":"International Journal of Pharmacy and Pharmaceutical Sciences"},{"issue":"8","key":"3230_CR22","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1177\/0960327119843586","volume":"38","author":"JS Hussein","year":"2019","unstructured":"Hussein, J. S., Rasheed, W., Ramzy, T., Nabeeh, M., Harvy, M., El-Toukhy, S., Ali, O., Raafat, J., & El-Naggar, M. (2019b). Synthesis of docosahexaenoic acid\u2013loaded silver nanoparticles for improving endothelial dysfunctions in experimental diabetes. Human and Experimental Toxicology, 38(8), 962\u2013973.","journal-title":"Human and Experimental Toxicology"},{"issue":"13","key":"3230_CR23","first-page":"247","volume":"8","author":"J Hussein","year":"2016","unstructured":"Hussein, J., El-Khayat, Z., Abdel Latif, Y., & Khateeb, S. (2016). Quercetin ameliorates endothelial dysfunction and prevents elevation of asymmetrical dimethylarginine in experimental diabetes. Der Pharma Chemica, 8(13), 247\u2013252.","journal-title":"Der Pharma Chemica"},{"key":"3230_CR24","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jff.2017.08.011","volume":"37","author":"J Hussein","year":"2017","unstructured":"Hussein, J., El-Bana, M., Refaat, E., & El-Naggar, M. E. (2017). Synthesis of carvacrol-based nanoemulsion for treating neurodegenerative disorders in experimental diabetes. Journal of Functional Foods, 37, 441\u2013448.","journal-title":"Journal of Functional Foods"},{"key":"3230_CR25","doi-asserted-by":"crossref","first-page":"5804","DOI":"10.1021\/acsami.5b11409","volume":"8","author":"P Shah","year":"2016","unstructured":"Shah, P., Zhu, X., Zhang, X., He, J., & Li, C. (2016). Microelectromechanical system-based sensing arrays for comparative in vitro nanotoxicity assessment at single cell and small cell-population using electrochemical impedance spectroscopy. ACS Applied Materials & Interfaces, 8, 5804\u20135812.","journal-title":"ACS Applied Materials & Interfaces"},{"key":"3230_CR26","first-page":"22","volume":"10","author":"D Krishna","year":"2012","unstructured":"Krishna, D., Rao, S., & Satyanarayana, M. L. (2012). Serum insulin levels and lipid profiles of streptozotocin induced diabetic Wistar rats. Journal Indian Veterinary Association, 10, 22\u201326.","journal-title":"Journal Indian Veterinary Association"},{"key":"3230_CR27","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1007\/s12010-018-2803-6","volume":"187","author":"L Kou","year":"2019","unstructured":"Kou, L., Du, M., Liu, P., Zhang, B., Zhang, Y., Yang, P., Shang, M., & Wang, X. (2019). Anti-diabetic and anti-nephritic activities of Grifola frondosa mycelium polysaccharides in diet-streptozotocin-induced diabetic rats via modulation on oxidative stress. Applied Biochemistry and Biotechnology, 187, 310\u2013322.","journal-title":"Applied Biochemistry and Biotechnology"},{"issue":"6","key":"3230_CR28","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1161\/HYPERTENSIONAHA.107.104059","volume":"51","author":"JF Argacha","year":"2008","unstructured":"Argacha, J. F., Adamopoulos, D., Gujic, M., Fontaine, D., Amyai, N., Berkenboom, G., & van de Borne, P. (2008). Acute effects of passive smoking on peripheral vascular function. Hypertension, 51(6), 1506\u20131511.","journal-title":"Hypertension"},{"issue":"1","key":"3230_CR29","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/S0008-6363(02)00617-X","volume":"57","author":"K Sydow","year":"2003","unstructured":"Sydow, K., Schwedhelm, E., Arakawa, N., Bode-B\u00f6ger, S. M., Tsikas, D., Hornig, B., Fr\u00f6lich, J. C., & B\u00f6ger, R. H. (2003). ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocysteinemia: effects of l-arginine and B vitamins. Cardiovascular Research, 57(1), 244\u2013252.","journal-title":"Cardiovascular Research"},{"key":"3230_CR30","doi-asserted-by":"crossref","first-page":"86","DOI":"10.4103\/jasmr.jasmr_26_17","volume":"12","author":"O Aly","year":"2017","unstructured":"Aly, O., Elias, T. R., Agaiby, M. H., Rasheed, W. I., Ashour, M. N., & Hussein, J. S. (2017). Role of a combination of myrtle extract and fish oil supplementation in improving endothelial dysfunction in streptozotocin-induced diabetic rats. Journal of The Arab Society for Medical, 12, 86\u201391.","journal-title":"Journal of The Arab Society for Medical"},{"issue":"1\u20132","key":"3230_CR31","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0009-8981(02)00287-5","volume":"326","author":"MT Agullo-Ortuno","year":"2002","unstructured":"Agullo-Ortuno, M. T., Albaladejo, M. D., Parra, S., Rodriguez-Manotas, M., Fenollar, M., Ru\u00edz-Espejo, F., Teba, J., & Mart\u00ednez, P. (2002). Plasmatic homocysteine concentration and its relationship with complications associated to diabetes mellitus. Clinica Chimica Acta, 326(1\u20132), 105\u2013112.","journal-title":"Clinica Chimica Acta"},{"issue":"3","key":"3230_CR32","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2337\/diacare.24.3.533","volume":"24","author":"M Emoto","year":"2001","unstructured":"Emoto, M., Kanda, H., Shoji, T., Kawagishi, T., Komatsu, M., Mori, K., Tahara, H., Ishimura, E., Inaba, M., Okuno, Y., & Nishizawa, Y. (2001). Impact of insulin resistance and nephropathy on homocysteine in type 2 diabetes. Diabetes Care, 24(3), 533\u2013538.","journal-title":"Diabetes Care"},{"key":"3230_CR33","first-page":"11","volume":"1","author":"I Tarkun","year":"2003","unstructured":"Tarkun, I., Arslan, B. C., Cant\u00fcrk, Z., Tarkun, P., Kozda\u011f, G., & Topsever, P. (2003). Homocysteine concentrations in type 2 diabetes mellitus patients without cardiovascular disease: relationship to metabolic parameters and diabetic complications. Turkish Journal of Endocrinology and Metabolism, 1, 11\u201317.","journal-title":"Turkish Journal of Endocrinology and Metabolism"},{"key":"3230_CR34","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1161\/01.RES.87.1.45","volume":"87","author":"H Jakubowski","year":"2000","unstructured":"Jakubowski, H., Zhang, L., Bardeguez, A., & Aviv, A. (2000). Homocysteine thiolactone and protein homocysteinylation in human endothelial cells. Circulation Research, 87, 45\u201351.","journal-title":"Circulation Research"},{"key":"3230_CR35","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.ijpharm.2018.06.023","volume":"547","author":"M Akbariana","year":"2018","unstructured":"Akbariana, M., Ghasemib, Y., Vladimir, N., Verskyc, D., & Yousefia, R. (2018). Chemical modifications of insulin: finding a compromise between stability and pharmaceutical performance. International Journal of Pharmaceutics, 547, 450\u2013468.","journal-title":"International Journal of Pharmaceutics"},{"key":"3230_CR36","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1177\/1358836X0501000105","volume":"10","author":"S Dayal","year":"2005","unstructured":"Dayal, S., & Lentz, S. R. (2005). ADMA and hyperhomocysteinemia. Vascular Medicine, 10, S27\u2013S33.","journal-title":"Vascular Medicine"},{"issue":"1","key":"3230_CR37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.atherosclerosis.2009.03.008","volume":"205","author":"JC Fruchart","year":"2009","unstructured":"Fruchart, J. C. (2009). Peroxisome proliferator-activated receptor-alpha(PPAR\u03b1): at the crossroads of obesity, diabetes and cardiovascular disease. Atherosclerosis, 205(1), 1\u20138.","journal-title":"Atherosclerosis"},{"issue":"22","key":"3230_CR38","doi-asserted-by":"crossref","first-page":"16638","DOI":"10.1074\/jbc.275.22.16638","volume":"275","author":"M Guerre-Millo","year":"2000","unstructured":"Guerre-Millo, M., Gervois, P., Raspe, E., Madsen, L., Poulain, P., Derudas, B., Herbert, J. M., Winegar, D. A., Willson, T. M., Fruchart, J. C., Berge, R. K., & Staels, B. (2000). Peroxisome proliferator-activated receptor \u03b1 activators improve insulin sensitivity and reduce adiposity. The Journal of Biological Chemistry, 275(22), 16638\u201316642.","journal-title":"The Journal of Biological Chemistry"},{"issue":"11","key":"3230_CR39","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1007\/s11745-004-1339-7","volume":"39","author":"CN Serhan","year":"2004","unstructured":"Serhan, C. N., Arita, M., Hong, S., & Gotlinger, K. (2004). Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin triggered epimers. Lipids, 39(11), 1125\u20131132.","journal-title":"Lipids"},{"issue":"20","key":"3230_CR40","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1016\/j.jacc.2011.06.063","volume":"58","author":"D Mozaffarian","year":"2011","unstructured":"Mozaffarian, D., & Wu, J. H. (2011). Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. Journal of the American College of Cardiology, 58(20), 2047\u20132067.","journal-title":"Journal of the American College of Cardiology"},{"issue":"1","key":"3230_CR41","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.nut.2009.05.015","volume":"26","author":"T Huang","year":"2010","unstructured":"Huang, T., Wahlqvist, M. L., & Li, D. (2010). Docosahexaenoic acid decreases plasma homocysteine via regulating enzyme activity and mRNA expression involved in methionine metabolism. Nutrition, 26(1), 112\u2013119.","journal-title":"Nutrition"},{"key":"3230_CR42","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.biopha.2016.07.052","volume":"83","author":"T Shaheen","year":"2016","unstructured":"Shaheen, T., El-Naggar, M. E., Hussein, J. S., El-Bana, M., Emara, E., El-Khayat, Z., Moustafa, M. G., Hossam, F. E., & Hebeisha, A. (2016). Antidiabetic assessment; in vivo study of gold and core-shell silver-gold nanoparticles on streptozotocin-induced diabetic rats. Biomedicine & Pharmacotherapy, 83, 865\u2013875.","journal-title":"Biomedicine & Pharmacotherapy"},{"key":"3230_CR43","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.biopha.2017.04.020","volume":"90","author":"J Hussein","year":"2017","unstructured":"Hussein, J., El-Banna, M., Mahmoud, K. F., Morsy, S., Abdel Latif, Y., Medhat, D., Refaat, E., Farrag, A. H., & El-Daly, S. M. (2017). The therapeutic effect of nano-encapsulated and nano-emulsion forms of carvacrol on experimental liver fibrosis. Biomedicine & Pharmacotherapy, 90, 880\u2013887.","journal-title":"Biomedicine & Pharmacotherapy"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-020-03230-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12010-020-03230-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-020-03230-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T00:13:33Z","timestamp":1611101613000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12010-020-03230-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,21]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["3230"],"URL":"https:\/\/doi.org\/10.1007\/s12010-020-03230-z","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,21]]},"assertion":[{"value":"3 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 January 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}