{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T09:50:22Z","timestamp":1780739422164,"version":"3.54.1"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T00:00:00Z","timestamp":1613520000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T00:00:00Z","timestamp":1613520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Science and Engineering Research Board (SERB), Department of Science and Technology, Government of India","award":["EMR\/2016\/001670 dated 22.08.17"],"award-info":[{"award-number":["EMR\/2016\/001670 dated 22.08.17"]}]},{"name":"Department of Higher Education, Science & Technology and Biotechnology, Government of West Bengal, India","award":["62(Sanc.)\/BT\/P\/Budget\/RD-60\/2017 dated 12.03.2018"],"award-info":[{"award-number":["62(Sanc.)\/BT\/P\/Budget\/RD-60\/2017 dated 12.03.2018"]}]},{"name":"INSPIRE fellowship grant from Department of Science &Technology, New Delhi, Government of India","award":["DST\/INSPIRE Fellowship\/2016\/ IF160069 (2016-2019)"],"award-info":[{"award-number":["DST\/INSPIRE Fellowship\/2016\/ IF160069 (2016-2019)"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1007\/s12010-021-03521-z","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T12:04:46Z","timestamp":1613736286000},"page":"2267-2296","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Uropathogenic Escherichia coli in India\u2014an Overview on Recent Research Advancements and Trends"],"prefix":"10.1007","volume":"193","author":[{"given":"Arunita","family":"Ghosh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debojyoty","family":"Bandyopadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Snehashis","family":"Koley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandira","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,17]]},"reference":[{"key":"3521_CR1","doi-asserted-by":"crossref","unstructured":"Karigoudar, R. M., Karigoudar, M. H., Wavare, S. M., & Mangalgi, S. S. (2019). Detection of biofilm among uropathogenic Escherichia coli and its correlation with antibiotic resistance pattern. Journal of Laboratory Physicians, 11 [01], 017-022.","DOI":"10.4103\/JLP.JLP_98_18"},{"key":"3521_CR2","doi-asserted-by":"crossref","unstructured":"Ghosh, A., & Mukherjee, M. (2019). Incidence of multidrug resistance, pathogenicity island markers, and pathoadaptive FimH mutations in uropathogenic Escherichia coli isolated from asymptomatic hospitalized patients. Folia Microbiologica, 64(4), 587-600","DOI":"10.1007\/s12223-019-00685-4"},{"key":"3521_CR3","doi-asserted-by":"crossref","unstructured":"Paralikar, P., Ingle, A.P., Tiwari, V., Golinska, P., Dahm, H., & Rai, M. (2019). Evaluation of antibacterial efficacy of sulfur nanoparticles alone and in combination with antibiotics against multidrug-resistant uropathogenic bacteria. Journal of Environmental Science and Health, Part A, 54[5], 381-390.","DOI":"10.1080\/10934529.2018.1558892"},{"key":"3521_CR4","doi-asserted-by":"crossref","unstructured":"Gopichand, P., Agarwal, G., Natarajan, M., Mandal, J., Deepanjali, S., Parameswaran, S., & Dorairajan, L.N. (2019). In vitro effect of fosfomycin on multi-drug resistant gram-negative bacteria causing urinary tract infections. Infection and Drug Resistance, Volume 12, 2005-2013.","DOI":"10.2147\/IDR.S207569"},{"key":"3521_CR5","doi-asserted-by":"crossref","unstructured":"Malik, S., Sidhu, P.K., Rana, J.S., & Nehra, K. (2019). Managing urinary tract infections through phage therapy: a novel approach. Folia Microbiologica, 65[2], 217-231.","DOI":"10.1007\/s12223-019-00750-y"},{"key":"3521_CR6","doi-asserted-by":"crossref","unstructured":"Prasada, S., Bhat, A., Bhat, S., Shenoy Mulki, S., & Tulasidas, S. (2019). Changing antibiotic susceptibility pattern in uropathogenic Escherichia coli over a period of 5 years in a tertiary care center. Infection and Drug Resistance, Volume 12, 1439-1443.","DOI":"10.2147\/IDR.S201849"},{"key":"3521_CR7","doi-asserted-by":"crossref","unstructured":"Pullanhi, U., Khan, S., Vinod, V., Mohan, K., & Kumar, A. (2019). Outcome of acute urinary tract infections caused by uropathogenic Escherichia coli with phenotypically demonstrable virulence factors. Annals of African Medicine, 18[3], 138. .","DOI":"10.4103\/aam.aam_49_18"},{"key":"3521_CR8","doi-asserted-by":"crossref","unstructured":"Kaza, P., Mahindroo, J., Veeraraghavan, B., Mavuduru, R. S., Mohan, B., & Taneja, N. (2019). Evaluation of risk factors for colistin resistance among uropathogenic isolates of Escherichia coli and Klebsiella pneumoniae: a case\u2013control study. Journal of Medical Microbiology, 68[6], 837-847","DOI":"10.1099\/jmm.0.000986"},{"key":"3521_CR9","doi-asserted-by":"crossref","unstructured":"Mukherjee, S. K., & Mukherjee, M. (2019). Characterization and bio-typing of multidrug resistance plasmids from uropathogenic Escherichia coli isolated from clinical setting. Frontiers in Microbiology, 10.","DOI":"10.3389\/fmicb.2019.02913"},{"key":"3521_CR10","doi-asserted-by":"crossref","unstructured":"Bala Subramaniyan, S., Senthilnathan, R., Arunachalam, J., & Anbazhagan, V. (2019). Revealing the significance of the glycan binding property of Butea monosperma seed lectin for enhancing the antibiofilm activity of silver nanoparticles against uropathogenic Escherichia coli. Bioconjugate Chemistry, 31[1], 139-148.","DOI":"10.1021\/acs.bioconjchem.9b00821"},{"key":"3521_CR11","doi-asserted-by":"crossref","unstructured":"Rubini, D., Varthan, P. V., Jayasankari, S., Vedahari, B. N., & Nithyanand, P. (2020). Suppressing the phenotypic virulence factors of uropathogenic Escherichia coli using marine polysaccharide. Microbial Pathogenesis, 141, 103973","DOI":"10.1016\/j.micpath.2020.103973"},{"key":"3521_CR12","doi-asserted-by":"crossref","unstructured":"Verma, V., Kumar, P., Gupta, S., Yadav, S., Dhanda, R.S., Thorlacius, H., & Yadav, M. (2020). \u03b1-Hemolysin of uropathogenic E. coli regulates NLRP3 inflammasome activation and mitochondrial dysfunction in THP-1 macrophages. Scientific Reports, 10[1]. doi:10.1038\/s41598-020-69501-1","DOI":"10.1038\/s41598-020-69501-1"},{"key":"3521_CR13","doi-asserted-by":"crossref","unstructured":"Ghosh, B., & Mukherjee, M. (2016). Emergence of co-production of plasmid-mediated AmpC beta-lactamase and ESBL in cefoxitin-resistant uropathogenic Escherichia coli. European Journal of Clinical Microbiology & Infectious Diseases, 35(9), 1449-1454.","DOI":"10.1007\/s10096-016-2683-z"},{"key":"3521_CR14","doi-asserted-by":"crossref","unstructured":"Basu, S., & Mukherjee, M. (2019). Conjugal transfer of PMQR from uropathogenic E.coli under high ciprofloxacin selection pressure generates gyrA mutation. Microbial Pathogenesis, 132, 26-29.","DOI":"10.1016\/j.micpath.2019.04.021"},{"key":"3521_CR15","doi-asserted-by":"crossref","unstructured":"Gnanasekaran, A., Manikandan, P., Poongothai, P., Senthilkumar, P.K. (2019). In vitro screening of multidrug resistance uropathogenic Escherichia coli from the urban area of Namakkal district. Journal of Applied Pharmaceutical Science, 9(9), 84\u201391.","DOI":"10.7324\/JAPS.2019.90912"},{"key":"3521_CR16","doi-asserted-by":"crossref","unstructured":"Muraleetharan, M., Viswanathan, T., (2019). Genotyping and molecular characterization of extended-spectrum beta-lactamases-producing uropathogenic Escherichia coli in and around Coimbatore district, Tamil Nadu, India. Urological Science ; 30: 244","DOI":"10.4103\/UROS.UROS_45_19"},{"key":"3521_CR17","doi-asserted-by":"crossref","unstructured":"Kammili, N., Rani, M., Styczynski, A., Latha, M., Pavuluri, P. R., Reddy, V., & Alsan, M. (2020). Plasmid-mediated antibiotic resistance among uropathogens in primigravid women\u2014Hyderabad, India. Plos One, 15(5). doi:10.1371\/journal.pone.0232710","DOI":"10.1371\/journal.pone.0232710"},{"key":"3521_CR18","doi-asserted-by":"crossref","unstructured":"Siddaramappa, S., Pullela, K., Thimmappa, B., Devkota, R., Bajaj, R., Manivannan, B., . . . Pradeep, B. E. (2018). Characterization of blaCTX-M sequences of Indian origin and thirteen uropathogenic Escherichia coli isolates resistant to multiple antibiotics. BMC Research Notes, 11(1).","DOI":"10.1186\/s13104-018-3735-5"},{"key":"3521_CR19","doi-asserted-by":"crossref","unstructured":"Mehrishi, P., Faujdar, S.S., Kumar, S., Solanki, S., Sharma, A. (2019) Antibiotic susceptibility profile of uropathogens in rural population of Himachal Pradesh, India: where we are heading? Biomedical & Biotechnology Research Journal, 3:171-5","DOI":"10.4103\/bbrj.bbrj_128_19"},{"key":"3521_CR20","doi-asserted-by":"crossref","unstructured":"Mittal, S., Sharma, M., & Chaudhary, U. (2015 a). Biofilm and multidrug resistance in uropathogenic Escherichia coli. Pathogens and Global Health, 109(1), 26-29.","DOI":"10.1179\/2047773215Y.0000000001"},{"key":"3521_CR21","doi-asserted-by":"crossref","unstructured":"Miryala, S., Makala, H., Yadavali, S. P., Venkatasubramanian, U., Subbaiah, N., & Srinandan, C. (2020). Disperse red 15 (DR15) impedes biofilm formation of uropathogenic Escherichia coli. Microbial Pathogenesis, 138, 103772.","DOI":"10.1016\/j.micpath.2019.103772"},{"key":"3521_CR22","doi-asserted-by":"crossref","unstructured":"Mittal, S., Sharma, M., & Chaudhary, U. (2015b). Fosfomycin use in multi drug resistant uropathogenic Escherichia coli. Infectious Disorders - Drug Targets, 15(3), 196-201.","DOI":"10.2174\/1871526515666150916141907"},{"key":"3521_CR23","doi-asserted-by":"crossref","unstructured":"Singh, S. K., Seema, K., & Gupta, M. (2016). Detection of Amp C \u03b2-lactamase and adherence factors in uropathogenic Escherichia coli isolated from aged patients. Microbial Pathogenesis, 100, 293-298","DOI":"10.1016\/j.micpath.2016.10.010"},{"key":"3521_CR24","doi-asserted-by":"crossref","unstructured":"Vasudevan, S., Selvan, G. T., Bhaskaran, S., Hari, N., & Solomon, A. P. (2020). Reciprocal cooperation of type A procyanidin and nitrofurantoin against multi-drug resistant (MDR) UPEC: a pH-dependent study. Frontiers in Cellular and Infection Microbiology, 10.","DOI":"10.3389\/fcimb.2020.00421"},{"key":"3521_CR25","doi-asserted-by":"crossref","unstructured":"Mukherjee, M., Koley, S., Mukherjee, S. K., Basu, S., Ghosh, B., & Chakraborty, S. (2015). Phylogenetic background of E. coli isolated from asymptomatic pregnant women from Kolkata, India. The Journal of Infection in Developing Countries, 9(07), 720-724.","DOI":"10.3855\/jidc.5771"},{"key":"3521_CR26","doi-asserted-by":"crossref","unstructured":"Biswas, B., Bhushan, S., Rajesh, A., Suraj, S. K., Lu, Y., Meinhardt, A., & Yenugu, S. (2015). Uropathogenic Escherichia coli (UPEC) induced antimicrobial gene expression in the male reproductive tract of rat: evaluation of the potential of Defensin 21 to limit infection. Andrology, 3(2), 368-375.","DOI":"10.1111\/andr.12012"},{"key":"3521_CR27","doi-asserted-by":"crossref","unstructured":"Manohar, P., Tamhankar, A. J., Lundborg, C. S., & Nachimuthu, R. (2019). Therapeutic characterization and efficacy of bacteriophage cocktails infecting Escherichia coli, Klebsiella pneumoniae, and Enterobacter species. Frontiers in Microbiology, 10.","DOI":"10.3389\/fmicb.2019.00574"},{"key":"3521_CR28","doi-asserted-by":"crossref","unstructured":"Shruti, S. R., & Rajasekaran, R. (2020). Identification of therapeutic peptide scaffold from tritrpticin family for urinary tract infections using in silico techniques. Journal of Biomolecular Structure and Dynamics, 38(15), 4407-4417","DOI":"10.1080\/07391102.2019.1680437"},{"key":"3521_CR29","doi-asserted-by":"crossref","unstructured":"Parra, G.I., Squires, R. B., Karangwa, C.K., Johnson, J.A., Lepore, C J , Sosnovtsev, S.V., & Green, K.Y. (2017). Static and evolving norovirus genotypes: implications for epidemiology and immunity. PLOS Pathog.2017 Jan 19; 13(1):e1006136.","DOI":"10.1371\/journal.ppat.1006136"},{"key":"3521_CR30","doi-asserted-by":"crossref","unstructured":"Yadav, S. (2018). Correlation analysis in biological studies. J Pract Cardiovasc Sci, 4:116-21.","DOI":"10.4103\/jpcs.jpcs_31_18"},{"key":"3521_CR31","doi-asserted-by":"crossref","unstructured":"Akoglu, H.(2018). User\u2019s guide to correlation coefficients. Turk J Emerg Med, 7; 18(3):91-93.","DOI":"10.1016\/j.tjem.2018.08.001"},{"key":"3521_CR32","unstructured":"Bhattacharyya, S., Sarfraz, A., Ansari, M.A.A., Jaiswal, N., (2015). Characterization and antibiogram of Uropathogenic Escherichia coli from a tertiary care hospital in Eastern India. Int J Curr Microbiol App Sci., 4(2): 701-705"},{"key":"3521_CR33","unstructured":"Wabale, V.R., Bharadwaj, R.S., Joshi, A.A., Chowdhary, A.S. (2015). Serotypes, Hemolysin production and drug resistance among uropathogenic Escherichia coli at a tertiary care hospital in Mumbai. International Journal of Current Research 7(07), 18596-18600"},{"key":"3521_CR34","unstructured":"Yadav, M., Khumanthem, S.V., Kshtrimayum, M.D. (2017). Antibiotic resistance trends of Uropathogenic Escherichia coli isolated from inpatients in a tertiary care hospital in north East India. International Journal of Recent Scientific Research. 8(7), 18496-18500"},{"key":"3521_CR35","doi-asserted-by":"crossref","unstructured":"Sukumaran,T.S., Mohan A.K. (2017). Antimicrobial resistance among uropathogenic bacteria in Rural Kerala, India. Int.J.Curr.Microbiol.App.Sci, 6(9): 2287-2296","DOI":"10.20546\/ijcmas.2017.609.280"},{"key":"3521_CR36","doi-asserted-by":"crossref","unstructured":"Mishra, M. P., Sarangi, R., & Padhy, R. N. (2016). Prevalence of multidrug resistant uropathogenic bacteria in pediatric patients of a tertiary care hospital in eastern India. Journal of Infection and Public Health, 9(3), 308-314.","DOI":"10.1016\/j.jiph.2015.10.002"},{"key":"3521_CR37","unstructured":"Tadepalli, S., Prudhivi, S., Myneni, R.B., Rao, S. (2016). Biofilm formation in uropathogenic Escherichia coli isolates and its association with extended betalactamase production and drug resistance. Saudi Journal of Pathology and Microbiology, 1(Iss-2), 60-64."},{"key":"3521_CR38","doi-asserted-by":"crossref","unstructured":"Bandyopadhyay, D., & Mukherjee, M., (2020). Reactive oxygen species and uspA overexpession: an alternative bacterial response toward selection and maintenance of multidrug resistance in clinical isolates of uropathogenic E. coli. European Journal of Clinical Microbiology & Infectious Diseases, 39(9), 1753-1760","DOI":"10.1007\/s10096-020-03903-x"},{"key":"3521_CR39","doi-asserted-by":"crossref","unstructured":"Vysakh, A., Midhun, S. J., Jayesh, K., Jyothis, M., & Latha, M. (2018). Studies on biofilm formation and virulence factors associated with uropathogenic Escherichia coli isolated from patient with acute pyelonephritis. Pathophysiology, 25(4), 381-387.","DOI":"10.1016\/j.pathophys.2018.07.004"},{"key":"3521_CR40","unstructured":"Bandyopadhyay D, Mukherjee M. (2017). Distribution of class D-oxacillinases amongst third generation cephalosporin resistant nosocomial uropathogenic Escherichia coli isolates, their phylogenetic background and clonal analysis International Journal of Current Research. 9(10) 59099-59106"},{"key":"3521_CR41","doi-asserted-by":"crossref","unstructured":"Singh, B. R. (2019). Quinolones and fluoroquinolones are useless to counter uropathogenic Escherichia coli infections (Letter). Infection and Drug Resistance, Volume 12, 2161-2162.","DOI":"10.2147\/IDR.S220394"},{"key":"3521_CR42","doi-asserted-by":"crossref","unstructured":"Basu, S., & Mukherjee, M. (2018). Incidence and risk of co-transmission of plasmid-mediated quinolone resistance and extended-spectrum \u03b2-lactamase genes in fluoroquinolone-resistant uropathogenic Escherichia coli: a first study from Kolkata, India. Journal of Global Antimicrobial Resistance, 14, 217-223.","DOI":"10.1016\/j.jgar.2018.03.009"},{"key":"3521_CR43","doi-asserted-by":"crossref","unstructured":"Das, B., Mittal, N., Goswami, R., Adhana, D., & Rathore, N. (2018). Prevalence of multidrug resistance (MDR) and extended spectrum beta-lactamases (ESBLs) among uropathogenic Escherichia coli isolates from female patients in a tertiary care hospital in North India. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 7(12), 5031","DOI":"10.18203\/2320-1770.ijrcog20184961"},{"key":"3521_CR44","doi-asserted-by":"crossref","unstructured":"Patwardhan, V., Kumar, D., Goel, V., & Singh, S. (2017). Changing prevalence and antibiotic drug resistance pattern of pathogens seen in community-acquired pediatric urinary tract infections at a tertiary care hospital of North India. Journal of Laboratory Physicians, 9(04), 264-268.","DOI":"10.4103\/JLP.JLP_149_16"},{"key":"3521_CR45","unstructured":"Thattil, S.J., & Santhosh, S. (2018). Prevalence of UTI in different age groups in a tertiary care hospital and their Antibiogram. International Journal of Contemporary Medical Research, 5(1), 2454-7379."},{"key":"3521_CR46","doi-asserted-by":"crossref","unstructured":"Jena, J., Sahoo, R. K., Debata, N. K., & Subudhi, E. (2017). Prevalence of TEM, SHV, and CTX-M genes of extended-spectrum \u03b2-lactamase-producing Escherichia coli strains isolated from urinary tract infections in adults. 3 Biotech, 7(4).","DOI":"10.1007\/s13205-017-0879-2"},{"key":"3521_CR47","doi-asserted-by":"crossref","unstructured":"Narayan, A., Gopi, S., Fushman, D., & Naganathan, A. N. (2019). A binding cooperativity switch driven by synergistic structural swelling of an osmo-regulatory protein pair. Nature Communications, 10(1).","DOI":"10.1038\/s41467-019-10002-9"},{"key":"3521_CR48","doi-asserted-by":"crossref","unstructured":"Verma, V., Gupta, S., Kumar, P., Yadav, S., Dhanda, R.S., Gaind, R., Arora, R., Frimodt-M\u00f8ller, N., & Yadav, M. (2019b). Involvement of NLRP3 and NLRC4 inflammasome in uropathogenic E. coli mediated urinary tract infections. Frontiers in Microbiology, 10. .","DOI":"10.3389\/fmicb.2019.02020"},{"key":"3521_CR49","doi-asserted-by":"crossref","unstructured":"Verma, V., Gupta, S., Kumar, P., Rawat, A., Singh Dhanda, R., & Yadav, M. (2019a). Efficient production of endotoxin depleted bioactive \u03b1-hemolysin of uropathogenic Escherichia coli. Preparative Biochemistry and Biotechnology, 49[6], 616-622.","DOI":"10.1080\/10826068.2019.1591993"},{"key":"3521_CR50","doi-asserted-by":"crossref","unstructured":"Pandey, N. K., Verma, G., Kushwaha, G. S., Suar, M., & Bhavesh, N. S. (2020). Crystal structure of the usher chaperone YadV reveals a monomer with the proline lock in closed conformation suggestive of an intermediate state. FEBS Letters, 594(18), 3057-3066.","DOI":"10.1002\/1873-3468.13883"},{"key":"3521_CR51","doi-asserted-by":"crossref","unstructured":"Zuberi, A., Ahmad, N., & Khan, A. U. (2017). CRISPRi induced suppression of fimbriae gene (fimH) of a uropathogenic Escherichia coli: an approach to inhibit microbial biofilms. Frontiers in Immunology, 8. doi:10.3389\/fimmu.2017.01552","DOI":"10.3389\/fimmu.2017.01552"},{"key":"3521_CR52","doi-asserted-by":"crossref","unstructured":"Mukherjee, S., Mandal, R., Das, S., & Mukherjee, M. (2018). Effect of non-\u03b2-lactams on stable variants of inhibitor-resistant TEM \u03b2-lactamase in uropathogenic Escherichia coli: implication for alternative therapy. Journal of Applied Microbiology, 124(3), 667-681.","DOI":"10.1111\/jam.13671"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-021-03521-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12010-021-03521-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-021-03521-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,18]],"date-time":"2022-12-18T05:44:02Z","timestamp":1671342242000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12010-021-03521-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,17]]},"references-count":52,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["3521"],"URL":"https:\/\/doi.org\/10.1007\/s12010-021-03521-z","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,17]]},"assertion":[{"value":"28 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publish"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}