{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:31:49Z","timestamp":1787164309775,"version":"build-2736575974"},"reference-count":82,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:00:00Z","timestamp":1659052800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:00:00Z","timestamp":1659052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1007\/s12010-021-03635-4","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T03:19:58Z","timestamp":1659064798000},"page":"6213-6254","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Antibacterial and Anti-inflammatory Activity of Extracts and Major Constituents Derived from Stachytarpheta indica Linn. Leaves and Their Potential Implications for Wound Healing"],"prefix":"10.1007","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4970-6587","authenticated-orcid":false,"given":"Vajira Asela","family":"Agampodi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Katavic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trudi","family":"Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,29]]},"reference":[{"key":"3635_CR1","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1111\/ijd.12766","volume":"54","author":"T Maver","year":"2015","unstructured":"Maver, T., Maver, U., Kleinschek, K. S., Smrke, D. M., & Kreft, S. (2015). A review of herbal medicines in wound healing. International Journal of Dermatology, 54, 740\u2013751.","journal-title":"International Journal of Dermatology"},{"issue":"1","key":"3635_CR2","doi-asserted-by":"publisher","first-page":"72","DOI":"10.3109\/15569527.2012.705407","volume":"32","author":"F \u00d6zt\u00fcrk","year":"2013","unstructured":"\u00d6zt\u00fcrk, F., Ermertcan, A. T., & \u0130nan\u0131r, I. (2013). Hyperbaric oxygen therapy for the management of chronic wounds. Cutaneous and Ocular Toxicology, 32(1), 72\u201377.","journal-title":"Cutaneous and Ocular Toxicology"},{"issue":"6","key":"3635_CR3","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1111\/j.1524-475X.2009.00543.x","volume":"17","author":"CK Sen","year":"2009","unstructured":"Sen, C. K., Gordillo, G. M., Roy, S., Kirsner, R., Lambert, L., Hunt, T. K., Gottrup, F., Gurtner, G. C., & Longaker, M. T. (2009). Human skin wounds: A major and snowballing threat to public health and the economy. Wound Repair and Regeneration, 17(6), 763\u2013771.","journal-title":"Wound Repair and Regeneration"},{"key":"3635_CR4","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1007\/s00403-009-1011-1","volume":"302","author":"C Wiegand","year":"2010","unstructured":"Wiegand, C., Sch\u00f6nfelder, U., Abel, M., Ruth, P., Kaatz, M., & Hipler, U.-C. (2010). Protease and pro-inXammatory cytokine concentrations are elevated in chronic compared to acute wounds and can be modulated by collagen type I in vitro. Archives of Dermatological Research, 302, 419\u2013428.","journal-title":"Archives of Dermatological Research"},{"key":"3635_CR5","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.biopha.2018.06.141","volume":"106","author":"J Choi","year":"2018","unstructured":"Choi, J., Park, Y.-G., Yun, M.-S., & Seol, J.-W. (2018). Effect of herbal mixture composed of Alchemilla vulgaris and Mimosa on wound healing process. Biomedicine and Pharmacotherapy, 106, 326\u2013332.","journal-title":"Biomedicine and Pharmacotherapy"},{"key":"3635_CR6","doi-asserted-by":"publisher","first-page":"52","DOI":"10.12968\/jowc.2004.13.2.26575","volume":"13","author":"MJ Leach","year":"2004","unstructured":"Leach, M. J. (2004). Making sense of the venous leg ulcer debate: A literature review. Journal of Wound Care, 13, 52\u201356.","journal-title":"Journal of Wound Care"},{"key":"3635_CR7","doi-asserted-by":"publisher","first-page":"65S","DOI":"10.1016\/S0002-9610(03)00306-4","volume":"187","author":"T Mustoe","year":"2004","unstructured":"Mustoe, T. (2004). Understanding chronic wounds: A unifying hypothesis on their pathogenesis and implications for therapy. The American Journal of Surgery, 187, 65S-70S.","journal-title":"The American Journal of Surgery"},{"key":"3635_CR8","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1111\/j.1524-475X.2012.00836.x","volume":"20","author":"SL Percival","year":"2012","unstructured":"Percival, S. L., Hill, K. E., Williams, D. W., Hooper, S. J., Thomas, D. W., & Costerton, J. W. (2012). A review of the scientific evidence for biofilms in wounds. Wound Repair and Regeneration, 20, 647\u2013657.","journal-title":"Wound Repair and Regeneration"},{"key":"3635_CR9","unstructured":"Global Advanced Wound Care Products Industry 2020. Available from: https:\/\/www.globenewswire.com\/news-release\/2020\/09\/04\/2089098\/0\/en\/Global-Advanced-Wound-Care-Products-Industry.html. Accessed March 10, 2021."},{"key":"3635_CR10","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/S0378-8741(01)00290-2","volume":"77","author":"EA Palombo","year":"2001","unstructured":"Palombo, E. A., & Semple, S. J. (2001). Antibacterial activity of traditional Australian medicinal plants. Journal of Ethnopharmacology, 77, 151\u2013157.","journal-title":"Journal of Ethnopharmacology"},{"issue":"25","key":"3635_CR11","first-page":"2886","volume":"6","author":"T Sibanda","year":"2007","unstructured":"Sibanda, T., & Okoh, A. I. (2007). The challenges of overcoming antibiotic resistance: Plant extracts as potential sources of antimicrobial and resistance modifying agents. African Journal of Biotechnology, 6(25), 2886\u20132896.","journal-title":"African Journal of Biotechnology"},{"issue":"3","key":"3635_CR12","first-page":"249","volume":"11","author":"AA Mariod","year":"2012","unstructured":"Mariod, A. A., Abdelwahab, S. I., Elkheir, S., Ahmed, Y. M., Fauzi, P. N. M., & Chuen, C. S. (2012). Antioxident activity of different parts from Annona squamosa and Catuaregam nilotica methanolic extract. Acta Scientiarum Polonorum, 11(3), 249\u2013257.","journal-title":"Acta Scientiarum Polonorum"},{"key":"3635_CR13","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.jep.2006.02.020","volume":"107","author":"RP Samy","year":"2006","unstructured":"Samy, R. P., Gopalakrishnakone, P., Houghton, P., & Ignacimuthu, S. (2006). Purification of antibacterial agents from Tragia involucrata\u2013a popular tribal medicine for wound healing. Journal of Ethnopharmacology, 107, 99\u2013106.","journal-title":"Journal of Ethnopharmacology"},{"key":"3635_CR14","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.jep.2014.02.044","volume":"153","author":"AS Buru","year":"2014","unstructured":"Buru, A. S., Pichika, M. R., Neela, V., & Mohandas, K. (2014). In vitro antibacterial effects of Cinnamomum extracts on common bacteria found in wound infections with emphasis on methicillin-resistant Staphylococcus aureus. Journal of Ethnopharmacology, 153, 587\u2013595.","journal-title":"Journal of Ethnopharmacology"},{"issue":"2","key":"3635_CR15","first-page":"5","volume":"2","author":"SB Somashekar","year":"2013","unstructured":"Somashekar, S. B. (2013). Wound healing and indigenous drugs: Role as antioxidants: A review. Journal of Medical and Health Sciences, 2(2), 5\u201316.","journal-title":"Journal of Medical and Health Sciences"},{"issue":"5","key":"3635_CR16","doi-asserted-by":"publisher","first-page":"760","DOI":"10.18433\/J3831V","volume":"16","author":"PK Ghosh","year":"2013","unstructured":"Ghosh, P. K., & Gaba, A. (2013). Phyto-extracts in wound healing. Journal of Pharmacy and Pharmaceutical Science, 16(5), 760\u2013820.","journal-title":"Journal of Pharmacy and Pharmaceutical Science"},{"issue":"2","key":"3635_CR17","first-page":"156","volume":"75","author":"D Biswas","year":"2013","unstructured":"Biswas, D., Yoganandam, G., Dey, A., & Deb, L. (2013). Evaluation of antimicrobial and wound healing potentials of ethanol extract of wedelia biflora Linn D. C. leaves. Indian Journal of Pharmaceutical Sciences, 75(2), 156\u2013161.","journal-title":"Indian Journal of Pharmaceutical Sciences"},{"key":"3635_CR18","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1002\/bjs.1800780729","volume":"78","author":"SR Baker","year":"1991","unstructured":"Baker, S. R., Stacey, M. C., Jopp-McKay, A. G., Hoskin, S. E., & Thompson, P. J. (1991). Epidemiology of chronic venous ulcers. British Journal of Surgery, 78, 864\u2013867.","journal-title":"British Journal of Surgery"},{"issue":"1","key":"3635_CR19","first-page":"4","volume":"6","author":"HN Krishna Kumar","year":"2012","unstructured":"Krishna Kumar, H. N., Bhavyashree, K. G., & Chauhan, J. B. (2012). Phytochemical screening and antibacterial activity of Stachytarpheta indica. Global Journal of Pharmacology, 6(1), 4\u20137.","journal-title":"Global Journal of Pharmacology"},{"key":"3635_CR20","first-page":"83","volume":"16","author":"GT Chandler","year":"2014","unstructured":"Chandler, G. T., Westaway, J. O., & Conn, B. J. (2014). Taxanomic uncertainty of Stachytarpheta (Verbenaceae) in the Asia-Pacific and implications for invasive weed recognition and management. Journal of Plant Systematics, 16, 83\u201388.","journal-title":"Journal of Plant Systematics"},{"issue":"11","key":"3635_CR21","first-page":"460","volume":"9","author":"MHW Rozianoor","year":"2014","unstructured":"Rozianoor, M. H. W., Nadia, K. N., & Nurdiana, S. (2014). Stachytarpheta jamaicensis ethanolic leaf extract as wound healer on alloxan-induced diabetic Sprague Dawley rats. Bio technology An Indian Jouirnal, 9(11), 460\u2013466.","journal-title":"Bio technology An Indian Jouirnal"},{"issue":"1","key":"3635_CR22","first-page":"174","volume":"1","author":"VG Joshi","year":"2010","unstructured":"Joshi, V. G., Sutar, P. S., Kargar, A. A., Patil, S. A., Gopalakrishna, B., & Sureban, R. R. (2010). Screening of ethanolic extract of Stachytarpheta indica L. (Vahl) leaves for hepatoprotective activity. International Journal of Research in Ayurveda and Pharmacy, 1(1), 174\u2013179.","journal-title":"International Journal of Research in Ayurveda and Pharmacy"},{"key":"3635_CR23","first-page":"36","volume":"1","author":"OO Sunday","year":"2008","unstructured":"Sunday, O. O., Uguru, O. M., & Akanbi, B. E. (2008). Anti-diarrhea effect of aqueous extracts of Momordica balsmina and Stachytarpheta indica in rats. Journal of Natural Products, 1, 36\u201345.","journal-title":"Journal of Natural Products"},{"issue":"1","key":"3635_CR24","first-page":"1027","volume":"3","author":"CA Ezeabara","year":"2015","unstructured":"Ezeabara, C. A., Orachu, L. A., & CU, O., Ilodibia, C. V., Emeka, A. N. & KU, E. . (2015). Comparative study of phytochemical, proximate and mineral compositions of Stachytarpheta cayannensis (L.C. Rich) Schau and Stachytarpheta indica (Linn.) Vahl. International Journal of Plant Biology and Research, 3(1), 1027.","journal-title":"International Journal of Plant Biology and Research"},{"issue":"2","key":"3635_CR25","first-page":"96","volume":"5","author":"S Princely","year":"2013","unstructured":"Princely, S., Basha, N. S., Kirubakaran, J. J., & Dhanaraju, M. D. (2013). Preliminary phytochemical screening and antimicrobial activity of aerial parts of Stachytarpheta indica L. (Vahl.). Medicinal Plants, 5(2), 96\u2013101.","journal-title":"Medicinal Plants"},{"issue":"1","key":"3635_CR26","doi-asserted-by":"publisher","first-page":"42","DOI":"10.4110\/in.2011.11.1.42","volume":"11","author":"C-E Hong","year":"2011","unstructured":"Hong, C.-E., & Lyu, S.-Y. (2011). Anti-inflammatory and anti-oxidative effects of Korean red ginseng extract in human keratinocytes. Immune Network, 11(1), 42\u201349.","journal-title":"Immune Network"},{"key":"3635_CR27","unstructured":"(2015) BD Cytometric Bead Array (CBA) Human inflammatory cytokines kit instruction manual. BD Biosciences, Becton, Dickinson and Company."},{"issue":"1","key":"3635_CR28","first-page":"1","volume":"3","author":"JK Gierse","year":"2001","unstructured":"Gierse, J. K., & Koboldt, C. M. (2001). Cyclooxygenase assays. Current protocols in pharmacology, 3(1), 1\u201316.","journal-title":"Current protocols in pharmacology"},{"issue":"2","key":"3635_CR29","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/S0962-4562(03)00083-3","volume":"13","author":"S Baylac","year":"2003","unstructured":"Baylac, S., & Racine, P. (2003). Inhibition of 5-lipoxygenase by essential oils and other natural fragrant extracts. International Journal of Aromatherapy, 13(2), 138\u2013142.","journal-title":"International Journal of Aromatherapy"},{"issue":"2","key":"3635_CR30","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1016\/j.foodchem.2009.07.010","volume":"119","author":"GPP Kamatou","year":"2010","unstructured":"Kamatou, G. P. P., Viljoen, A. M., & Steenkamp, P. (2010). Antioxidant, anti-inflammatory activities and HPLC analysis of South African Salvia species. Food Chemistry, 119(2), 684\u2013688.","journal-title":"Food Chemistry"},{"issue":"4","key":"3635_CR31","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1016\/S0031-9422(00)85058-X","volume":"23","author":"S Damtoft","year":"1984","unstructured":"Damtoft, S., Jensen, S. R., & Nielsen, B. J. (1984). The identity of the iridoid glucoside tarphetalin with ipolamiide. Phyrochemistry, 23(4), 907\u2013908.","journal-title":"Phyrochemistry"},{"issue":"40","key":"3635_CR32","first-page":"2","volume":"14","author":"S Javzan","year":"2013","unstructured":"Javzan, S., & Selenge, D. (2013). Phytochemical study of aerial parts from Phlomis tuberosa L. Mongolian Journal of Chemistry, 14(40), 2\u20133.","journal-title":"Mongolian Journal of Chemistry"},{"issue":"5","key":"3635_CR33","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1515\/znb-2004-0523","volume":"59","author":"H K\u0131rm\u0131z\u0131bekmez","year":"2004","unstructured":"K\u0131rm\u0131z\u0131bekmez, H., Piacente, S., Pizza, C., Donmez, A. A., & Calis, I. (2004). Iridoid and Phenylethanoid Glycosides from Phlomis nissolii and P. capitata. Zeitschrift f\u00fcr Naturforschung B, 59(5), 609\u2013613.","journal-title":"Zeitschrift f\u00fcr Naturforschung B"},{"key":"3635_CR34","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1002\/hlca.200790038","volume":"90","author":"FN Yal-A\u0131n","year":"2007","unstructured":"Yal-A\u0131n, F. N., Erscz, T., Avc\u0131c, K., Gotfredsen, C. H., Jensen, S. R., & Cal\u0131s, I. (2007). New iridoid glycosides from Lamium eriocephalum subsp. eriocephalum. Helvetica Chimica Acta, 90, 332\u2013336.","journal-title":"Helvetica Chimica Acta"},{"key":"3635_CR35","first-page":"227","volume":"28","author":"ZS Akdemir","year":"2004","unstructured":"Akdemir, Z. S., Tatli, I. I., Bedir, E., & Khan, I. A. (2004). Iridoid and phenylethanoid glycosides from Verbascum lasianthum. Turkish Journal of Chemistry, 28, 227\u2013234.","journal-title":"Turkish Journal of Chemistry"},{"key":"3635_CR36","doi-asserted-by":"publisher","first-page":"S56","DOI":"10.1002\/mrc.1260301312","volume":"30","author":"HC Krebs","year":"1992","unstructured":"Krebs, H. C., & Habermehl, G. G. (1992). Two-dimensional NMR spectroscopy of G1 ycosides. Magnetic Resonance in Chemistry, 30, S56\u2013S59.","journal-title":"Magnetic Resonance in Chemistry"},{"key":"3635_CR37","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1007\/s11418-012-0658-7","volume":"67","author":"C Phakeovilay","year":"2013","unstructured":"Phakeovilay, C., Disadee, W., Sahakitpichan, P., Sitthimonchai, S., Kittakoop, P., Ruchirawat, S., & Kanchanapoom, T. (2013). Phenylethanoid and flavone glycosides from Ruellia tuberosa L. Journal of Natural Medicines, 67, 228\u2013233.","journal-title":"Journal of Natural Medicines"},{"key":"3635_CR38","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.indcrop.2011.09.005","volume":"36","author":"YA Gomez-Aguirre","year":"2012","unstructured":"Gomez-Aguirre, Y. A., Zamilpa, A., Gonzalez-Cortazar, M., & Trejo-Tapia, G. (2012). Adventitious root cultures of Castilleja tenuiflora Benth. as a source of phenylethanoid glycosides. Industrial Crops and Products, 36, 188\u2013195.","journal-title":"Industrial Crops and Products"},{"key":"3635_CR39","first-page":"391","volume":"30","author":"Z Guvenalp","year":"2006","unstructured":"Guvenalp, Z., Ozbek, H., Unsalar, T., Kazaz, C., & Demirezer, L. O. (2006). Iridoid, flavonoid, and phenylethanoid glycosides from Wiedemannia orientalis. Turkish Journal of Chemistry, 30, 391\u2013400.","journal-title":"Turkish Journal of Chemistry"},{"key":"3635_CR40","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1007\/s00044-016-1677-9","volume":"25","author":"M Sobeh","year":"2016","unstructured":"Sobeh, M., Mamadalieva, N. Z., Mohamed, T., Krstin, S., Youssef, F. S., Ashour, M. L., Azimova, S. S., & Wink, M. (2016). Chemical profiling of Phlomis thapsoides (Lamiaceae) and in vitro testing of its biological activities. Medicinal Chemistry Research, 25, 2304\u20132315.","journal-title":"Medicinal Chemistry Research"},{"issue":"2","key":"3635_CR41","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1248\/cpb.55.159","volume":"55","author":"B Dinda","year":"2007","unstructured":"Dinda, B., Debnath, S., & Harigaya, Y. (2007). Naturally occurring iridoids. A Review, Part 1. Chemical and Pharmaceutical Bulletin Pharmaceutical Society of Japan, 55(2), 159\u2013222.","journal-title":"Chemical and Pharmaceutical Bulletin Pharmaceutical Society of Japan"},{"key":"3635_CR42","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.jep.2016.07.044","volume":"192","author":"CDC Maquiaveli","year":"2016","unstructured":"Maquiaveli, C. D. C., Sa, A. M. O., Vieira, P. C., Silva, E. R., & d. . (2016). Stachytarpheta cayennensis extract inhibits promastigote and amastigote growth in Leishmania amazonensis via parasitearginase inhibition. Journal of Ethnopharmacology, 192, 108\u2013113.","journal-title":"Journal of Ethnopharmacology"},{"issue":"3","key":"3635_CR43","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1080\/13880200490514203","volume":"42","author":"R Chowdhury","year":"2004","unstructured":"Chowdhury, R., Rashid, M. U., Khan, O. F., & Hasan, C. M. (2004). Bioactivity of extractives from Stachytarpheta urticaefolia. Pharmaceutical Biology, 42(3), 262\u2013267.","journal-title":"Pharmaceutical Biology"},{"issue":"3","key":"3635_CR44","first-page":"195","volume":"44","author":"I Calis","year":"2002","unstructured":"Calis, I., Kirmizibekmez, H., Ersoz, T., Saracoglu, I., Donmez, A. A., Mitova, M., Handjieva, N., & Popov, S. (2002). Iridoid, phenylethanoid and flavonoid glycosides from Phlomis sintenisii. Acta Pharmaceutica Turcica, 44(3), 195\u2013203.","journal-title":"Acta Pharmaceutica Turcica"},{"key":"3635_CR45","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.jep.2005.09.006","volume":"104","author":"C Penido","year":"2006","unstructured":"Penido, C., Costa, K. A., Futuro, D. O., Paiva, S. R., Kaplan, M. A. C., Figueiredo, M. R., & Henriques, M. G. M. O. (2006). Anti-inflammatory and anti-ulcerogenic properties of Stachytarpheta cayennensis (L.C. Rich) Vahl. Journal of Ethnopharmacology, 104, 225\u2013233.","journal-title":"Journal of Ethnopharmacology"},{"key":"3635_CR46","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.2174\/092986712800229005","volume":"19","author":"A Viljoen","year":"2012","unstructured":"Viljoen, A., Mncwangi, N., & Vermaak, I. (2012). Anti-inflammatory iridoids of botanical origin. Current Medicinal Chemistry, 19, 2104\u20132127.","journal-title":"Current Medicinal Chemistry"},{"key":"3635_CR47","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1016\/S0031-9422(00)98672-2","volume":"14","author":"B Tantisewie","year":"1975","unstructured":"Tantisewie, B., & Sticher, O. (1975). Isolation of ipolammide from Stachytarpheta Indica. Phytochemistry, 14, 1462\u20131463.","journal-title":"Phytochemistry"},{"issue":"9","key":"3635_CR48","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.2116\/analsci.18.1063","volume":"18","author":"S Roengsumran","year":"2002","unstructured":"Roengsumran, S., Sookkongwaree, K., Jaiboon, N., Chaichit, N., & Petsom, A. (2002). Crystal structure of ipolamiide monohydrate from Stachytarpheta indica. Analytical Sciences, 18(9), 1063\u20131064.","journal-title":"Analytical Sciences"},{"key":"3635_CR49","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1039\/c39810000228","volume":"5","author":"S Damtoft","year":"1981","unstructured":"Damtoft, S. (1981). Biosynthesis of lamiide and ipolamiide from 8-epi-deoxyloganin studied by 2H N.M.R. spectroscopy. Journal of the Chemical Society Chemical Communications, 5, 228\u2013229.","journal-title":"Journal of the Chemical Society Chemical Communications"},{"issue":"5","key":"3635_CR50","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1016\/S0031-9422(00)82429-2","volume":"21","author":"C Andary","year":"1982","unstructured":"Andary, C., Wylde, R., Laffite, C., Privat, G., & Winternitz, F. (1982). Structures of verbascoside and orobanchoside, caffeic acid sugar esters from Orobanche rapum-genistae. Phytochemistry, 21(5), 1123\u20131127.","journal-title":"Phytochemistry"},{"key":"3635_CR51","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.chroma.2004.11.024","volume":"1063","author":"L Li","year":"2005","unstructured":"Li, L., Tsao, R., Liu, Z., Liu, S., Yang, R., Young, J. C., Zhu, H., Deng, Z., Xie, M., & Fu, Z. (2005). Isolation and purification of acteoside and isoacteoside from Plantago psyllium L. by high-speed counter-current chromatography. Journal of Chromatography A, 1063, 161\u2013169.","journal-title":"Journal of Chromatography A"},{"key":"3635_CR52","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.cbi.2014.10.023","volume":"224","author":"AMS Pereira","year":"2014","unstructured":"Pereira, A. M. S., Hernandes, C., Pereira, S. I. V., Bertoni, B. W., Franca, S. C., Pereira, P. S., & Taleb-Contini, S. H. (2014). Evaluation of anticandidal and antioxidant activities of phenolic compounds from Pyrostegia venusta (Ker Gawl.) Miers. Chemico-Biological Interactions, 224, 136\u2013141.","journal-title":"Chemico-Biological Interactions"},{"issue":"2","key":"3635_CR53","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1021\/np50068a026","volume":"53","author":"GR Pettit","year":"1990","unstructured":"Pettit, G. R., Numata, A., Takemura, T., Ode, R. H., Narula, A. S., Schmidt, J. M., Cragg, G. M., & Pase, C. P. (1990). Antineoplastic agents, 107. Isolation of acteoside and isoacteoside from castilleja linariaefolia. Journal of Natural Products, 53(2), 456\u2013458.","journal-title":"Journal of Natural Products"},{"key":"3635_CR54","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/j.biotechadv.2014.07.001","volume":"32","author":"K Alipieva","year":"2014","unstructured":"Alipieva, K., Korkina, L., Orhan, I. E., & Georgiev, M. I. (2014). Verbascoside \u2014 a review of its occurrence, (bio)synthesis and pharmacological significance. Biotechnology Advances, 32, 1065\u20131076.","journal-title":"Biotechnology Advances"},{"issue":"4","key":"3635_CR55","doi-asserted-by":"publisher","first-page":"895","DOI":"10.3390\/ijms18040895","volume":"18","author":"Y-J Shiao","year":"2017","unstructured":"Shiao, Y.-J., Su, M.-H., Lin, H.-C., & Wu, C.-R. (2017). Acteoside and isoacteoside protect amyloid peptide induced cytotoxicity, cognitive deficit and neurochemical disturbances in vitro and in vivo. International Journal of Molecular Sciences, 18(4), 895.","journal-title":"International Journal of Molecular Sciences"},{"key":"3635_CR56","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1093\/chromsci\/bmt048","volume":"52","author":"C Chen","year":"2014","unstructured":"Chen, C., Zhao, X.-H., Yue, H.-L., Li, Y.-L., & Chen, T. (2014). Separation of phenylpropanoid glycosides from a Chinese herb by HSCCC. Journal of Chromatographic Science, 52, 395\u2013399.","journal-title":"Journal of Chromatographic Science"},{"issue":"6","key":"3635_CR57","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1590\/S0102-695X2010005000042","volume":"20","author":"PAD Souza","year":"2010","unstructured":"Souza, P. A. D., Silva, C. G., Machado, B. R. P., d Lucas, N. C., Leit\u00e3o, G. G., Eleutherio, E. C. A., Ortiz, G. M. D., & Benchetrit, L. C. (2010). Evaluation of antimicrobial, antioxidant and phototoxic activities of extracts and isolated compounds from Stachytarpheta cayennensis (Rich.) Vahl. Verbenaceae. Brazilian Journal of Pharmacognosy, 20(6), 922\u2013928.","journal-title":"Verbenaceae. Brazilian Journal of Pharmacognosy"},{"key":"3635_CR58","doi-asserted-by":"publisher","first-page":"8753","DOI":"10.1007\/s13277-015-4714-2","volume":"37","author":"P Sitarek","year":"2016","unstructured":"Sitarek, P., Ska\u0142a, E., Toma, M., Wielanek, M., Szemraj, J., Nieborowska-Skorska, M., Kolasa, M., Skorski, T., Wysoki\u0144ska, H., & \u015aliwi\u0144ski, T. (2016). A preliminary study of apoptosis induction in glioma cells via alteration of the Bax\/Bcl-2-p53 axis by transformed and non-transformed root extracts of Leonurus sibiricus L. Tumor Biology, 37, 8753\u20138764.","journal-title":"Tumor Biology"},{"key":"3635_CR59","doi-asserted-by":"publisher","first-page":"7068","DOI":"10.3390\/molecules16087068","volume":"16","author":"S Vertuani","year":"2011","unstructured":"Vertuani, S., Beghelli, E., Scalambra, E., Malisardi, G., Copetti, S., Toso, R. D., Baldisserotto, A., & Manfredini, S. (2011). Activity and stability studies of verbascoside, a novel antioxidant, in dermo-cosmetic and pharmaceutical topical formulations. Molecules, 16, 7068\u20137080.","journal-title":"Molecules"},{"key":"3635_CR60","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.foodchem.2017.04.137","volume":"233","author":"KSC Tang","year":"2017","unstructured":"Tang, K. S. C., Konczak, I., & Zhao, J. (2017). Phenolic compounds of the Australian native herb Prostanthera rotundifolia and their biological activities. Food Chemistry, 233, 530\u2013539.","journal-title":"Food Chemistry"},{"issue":"7","key":"3635_CR61","doi-asserted-by":"publisher","first-page":"354","DOI":"10.3923\/rjmp.2015.354.360","volume":"9","author":"L Etemad","year":"2015","unstructured":"Etemad, L., Zafari, R., Vahdati-Mashhadian, N., Moallem, S. A., Shirvan, Z. O., & Hosseinzadeh, H. (2015). Acute, sub-acute and cell toxicity of verbascoside. Research Journal of Medicinal Plant, 9(7), 354\u2013360.","journal-title":"Research Journal of Medicinal Plant"},{"issue":"12","key":"3635_CR62","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.1128\/am.16.12.1953-1954.1968","volume":"16","author":"H Basch","year":"1968","unstructured":"Basch, H., & Gadebusch, H. H. (1968). In vitro antimicrobial activity of dimethylsulfoxide. Applied Microbiology, 16(12), 1953\u20131954.","journal-title":"Applied Microbiology"},{"issue":"1","key":"3635_CR63","doi-asserted-by":"publisher","first-page":"81","DOI":"10.3347\/kjp.2017.55.1.81","volume":"55","author":"AM Cevallos","year":"2017","unstructured":"Cevallos, A. M., Herrera, J., & Hernandez, I.L.-V.R. (2017). Differential effects of two widely used solvents, DMSO and ethanol, on the growth and recovery of Trypanosoma cruzi Epimastigotes in Culture. Korean Journal of Parasitology, 55(1), 81\u201384.","journal-title":"Korean Journal of Parasitology"},{"issue":"2","key":"3635_CR64","doi-asserted-by":"publisher","first-page":"134","DOI":"10.4103\/ijmy.ijmy_35_18","volume":"7","author":"ZI Kirkwood","year":"2018","unstructured":"Kirkwood, Z. I., Millar, B. C., Downey, D. G., & Moore, J. E. (2018). Antimicrobial effect of dimethyl sulfoxide and N, N-dimethylformamide on Mycobacterium abscessus: Implications for antimicrobial susceptibility testing. International Journal of Mycobacteriology, 7(2), 134\u2013136.","journal-title":"International Journal of Mycobacteriology"},{"key":"3635_CR65","unstructured":"Tortora, G. G., Funke, B. R. & Case, C. L. (2015) Microbiology: an introduction 12 ed, Pearson Publication."},{"key":"3635_CR66","unstructured":"Willey, J. M., Sherwood, L. & Woolverton, C. (2007) Microbiology, 7 ed, McGraw-Hill Education."},{"key":"3635_CR67","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1002\/ptr.2061","volume":"21","author":"D Rigano","year":"2007","unstructured":"Rigano, D., Formisano, C., Basile, A., Lavitola, A., Senatore, F., Rosselli, S., & Bruno, M. (2007). Antibacterial activity of flavonoids and phenylpropanoids from Marrubium globosum ssp. libanoticum. Phytotherapy Research, 21, 395\u2013397.","journal-title":"Phytotherapy Research"},{"key":"3635_CR68","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/s11418-007-0194-z","volume":"62","author":"H Nazemiyeh","year":"2008","unstructured":"Nazemiyeh, H., Rahman, M. M., Gibbons, S., Nahar, L., Delazar, A., Ghahramani, M.-A., Talebpour, A.-H., & Sarker, S. D. (2008). Assessment of the antibacterial activity of phenylethanoid glycosides from Phlomis lanceolata against multiple-drug-resistant strains of Staphylococcus aureus. Journal of Natural Medicines, 62, 91\u201395.","journal-title":"Journal of Natural Medicines"},{"key":"3635_CR69","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.phytochem.2013.02.021","volume":"93","author":"EC Barnes","year":"2013","unstructured":"Barnes, E. C., Kavanagh, A. M., Ramu, S., Blaskovich, M. A., Cooper, M. A., & Davis, R. A. (2013). Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca. Phytochemistry, 93, 162\u2013169.","journal-title":"Phytochemistry"},{"issue":"1","key":"3635_CR70","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S0378-8741(98)00203-7","volume":"66","author":"JG Avila","year":"1999","unstructured":"Avila, J. G., d Liverant, J. G., Mart\u0131nez, A., Mart\u0131nez, G., Munoz, J. L., Arciniegas, A., & d Vivar, A. R. (1999). Mode of action of Buddleja cordata verbascoside against Staphylococcus aureus. Journal of Ethnopharmacology, 66(1), 75\u201378.","journal-title":"Journal of Ethnopharmacology"},{"key":"3635_CR71","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.chemphyslip.2009.11.004","volume":"163","author":"L Funes","year":"2010","unstructured":"Funes, L., Laporta, O., Cerdan-Calero, M., & Micol, V. (2010). Effects of verbascoside, a phenylpropanoid glycoside from lemon verbena, on phospholipid model membranes. Chemistry and Physics of Lipids, 163, 190\u2013199.","journal-title":"Chemistry and Physics of Lipids"},{"key":"3635_CR72","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1007\/s00138-018-0946-7","volume":"29","author":"L Han","year":"2018","unstructured":"Han, L., & Yin, Z. (2018). Learning to transfermicroscopy image modalities. Machine Vision and Applications, 29, 1257\u20131267.","journal-title":"Machine Vision and Applications"},{"key":"3635_CR73","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/s00709-003-0031-5","volume":"223","author":"G Kirfel","year":"2004","unstructured":"Kirfel, G., & Herzog, V. (2004). Migration of epidermal keratinocytes: Mechanisms, regulation, and biological significance. Protoplasma, 223, 67\u201378.","journal-title":"Protoplasma"},{"key":"3635_CR74","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1078\/0171-9335-00284","volume":"81","author":"G Kirfel","year":"2002","unstructured":"Kirfel, G., Borm, B., Rigort, A., & Herzog, V. (2002). The secretory \u03b2-amyloid precursor protein is a motogen for human epidermal keratinocytes. European Journal of Cell Biology, 81, 664\u2013676.","journal-title":"European Journal of Cell Biology"},{"key":"3635_CR75","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1078\/0171-9335-00117","volume":"79","author":"J Hoffmann","year":"2000","unstructured":"Hoffmann, J., Twiesselmann, C., Kummer, M. P., Romagnoli, P., & Herzog, V. (2000). A possible role for the Alzheimer amyloid precursor protien in the regulation of epidermal basal cell proliferation. European Journal of Cell Biology, 79, 905\u2013914.","journal-title":"European Journal of Cell Biology"},{"key":"3635_CR76","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1002\/ptr.3173","volume":"24","author":"L Speranza","year":"2010","unstructured":"Speranza, L., Franceschelli, S., Pesce, M., Reale, M., Menghini, L., Vinciguerra, I., Lutiis, M. A. D., Felaco, M., & Grilli, A. (2010). Antiinflammatory effects in THP-1 cells treated with verbascoside. Phytotherapy Research, 24, 1398\u20131404.","journal-title":"Phytotherapy Research"},{"key":"3635_CR77","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.jep.2017.08.028","volume":"210","author":"J-W Lee","year":"2018","unstructured":"Lee, J.-W., Seo, K.-H., Ryu, H. W., Yuk, H. J., Park, H. A., Lim, Y. R., Ahn, K.-S., & Oh, S.-R. (2018). Anti-inflammatory effect of stem bark of Paulownia tomentosa Steud. in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and LPS induced murine model of acute lung injury. Journal of Ethnopharmacology, 210, 23\u201330.","journal-title":"Journal of Ethnopharmacology"},{"key":"3635_CR78","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.ejphar.2011.02.022","volume":"658","author":"VA Kostyuk","year":"2011","unstructured":"Kostyuk, V. A., Potapovich, A. I., Suhan, T. O., d Luca, C., & Korkina, L. G. (2011). Antioxidant and signal modulation properties of plant polyphenols in controlling vascular inflammation. European Journal of Pharmacology, 658, 248\u2013256.","journal-title":"European Journal of Pharmacology"},{"issue":"4","key":"3635_CR79","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1089\/ars.2011.4053","volume":"16","author":"S Pastore","year":"2012","unstructured":"Pastore, S., Lulli, D., Fidanza, P., Potapovich, A. I., Kostyuk, V. A., Luca, C. D., Chik, E. M., & Korkina, L. G. (2012). Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system. Antioxidants and Redox Signaling, 16(4), 314\u2013328.","journal-title":"Antioxidants and Redox Signaling"},{"key":"3635_CR80","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1016\/j.jep.2012.10.035","volume":"144","author":"M Georgiev","year":"2012","unstructured":"Georgiev, M., Pastore, S., Lulli, D., Alipieva, K., Kostyuk, V., Potapovich, A., Panetta, M., & Korkina, L. (2012). Verbascum xanthophoeniceum-derived phenyl ethanoid glycosides are potent inhibitors of inflammatory chemokines in dormant and interferon-gamma-stimulated human keratinocytes. Journal of Ethnopharmacology, 144, 754\u2013760.","journal-title":"Journal of Ethnopharmacology"},{"key":"3635_CR81","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.jep.2018.07.012","volume":"225","author":"NDDM Sperotto","year":"2018","unstructured":"Sperotto, N. D. D. M., Luiza, S., Rodrigo, M. V., Jeferson, G. H., Valeria, F. P., Priscila, V., Jose, A. B. C., Adriana, R., Jenifer, S., & Dinara, J. M. (2018). Wound healing and anti-inflammatory activities induced by a Plantago australis hydroethanolic extract standardized in verbascoside. Journal of Ethnopharmacology, 225, 178\u2013188.","journal-title":"Journal of Ethnopharmacology"},{"key":"3635_CR82","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S0378-8741(97)00136-0","volume":"60","author":"EES Schapoval","year":"1998","unstructured":"Schapoval, E. E. S., d Vargas, M. R. W., Chaves, C. G., Bridi, R., Zuanazzi, J. A., & Henriques, A. T. (1998). Antiinflammatory and antinociceptive activities of extracts and isolated compounds from Stachytarpheta cayennensis. Journal of Ethnopharmacology, 60, 53\u201359.","journal-title":"Journal of Ethnopharmacology"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-021-03635-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12010-021-03635-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-021-03635-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,29]],"date-time":"2022-11-29T13:12:46Z","timestamp":1669727566000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12010-021-03635-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,29]]},"references-count":82,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["3635"],"URL":"https:\/\/doi.org\/10.1007\/s12010-021-03635-4","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,29]]},"assertion":[{"value":"18 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The management and use of the bio-specimens, Human immortalized keratinocyte cell line (HaCaT, Catalogue No.T0020001, Addexbio Technologies, USA) was accorded by the Human Research Ethics Committee, Queensland University of Technology, Brisbane, Australia (approval number: 1700001128).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}