{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:33:50Z","timestamp":1782840830621,"version":"3.54.5"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1007\/s12010-023-04586-8","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T09:02:11Z","timestamp":1689152531000},"page":"1636-1651","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Pharmacological Action of Baicalin on Gestational Diabetes Mellitus in Pregnant Animals Induced by Streptozotocin via AGE-RAGE Signaling Pathway"],"prefix":"10.1007","volume":"196","author":[{"given":"Shuqiong","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojie","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingke","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huirong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupak","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,7,12]]},"reference":[{"issue":"11","key":"4586_CR1","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1038\/nrendo.2012.96","volume":"8","author":"TA Buchanan","year":"2012","unstructured":"Buchanan, T. A., Xiang, A. H., & Page, K. A. (2012). Gestational diabetes mellitus: Risks and management during and after pregnancy. Nature Reviews Endocrinology, 8(11), 639\u2013649. https:\/\/doi.org\/10.1038\/nrendo.2012.96","journal-title":"Nature Reviews Endocrinology"},{"issue":"2","key":"4586_CR2","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1111\/j.1600-0412.2010.01030.x","volume":"90","author":"M Tikkanen","year":"2011","unstructured":"Tikkanen, M. (2011). Placental abruption: Epidemiology, risk factors and consequences: Placental abruption, epidemiology. Acta Obstetricia et Gynecologica Scandinavica, 90(2), 140\u2013149. https:\/\/doi.org\/10.1111\/j.1600-0412.2010.01030.x","journal-title":"Acta Obstetricia et Gynecologica Scandinavica"},{"issue":"10","key":"4586_CR3","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.3390\/biom10101359","volume":"10","author":"J Tozour","year":"2020","unstructured":"Tozour, J., Hughes, F., Carrier, A., Vieau, D., & Delahaye, F. (2020). Prenatal Hyperglycemia Exposure and Cellular Stress, a Sugar-Coated View of Early Programming of Metabolic Diseases. Biomolecules, 10(10), 1359. https:\/\/doi.org\/10.3390\/biom10101359","journal-title":"Biomolecules"},{"issue":"1\u20132","key":"4586_CR4","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1159\/000345205","volume":"4","author":"M Castori","year":"2013","unstructured":"Castori, M. (2013). Diabetic Embryopathy: A Developmental Perspective from Fertilization to Adulthood. Molecular Syndromology, 4(1\u20132), 74\u201386. https:\/\/doi.org\/10.1159\/000345205","journal-title":"Molecular Syndromology"},{"issue":"4","key":"4586_CR5","doi-asserted-by":"publisher","first-page":"2133","DOI":"10.1152\/physrev.00063.2017","volume":"98","author":"MC Petersen","year":"2018","unstructured":"Petersen, M. C., & Shulman, G. I. (2018). Mechanisms of Insulin Action and Insulin Resistance. Physiological Reviews, 98(4), 2133\u20132223. https:\/\/doi.org\/10.1152\/physrev.00063.2017","journal-title":"Physiological Reviews"},{"key":"4586_CR6","doi-asserted-by":"publisher","first-page":"329","DOI":"10.3389\/fendo.2017.00329","volume":"8","author":"R Tunduguru","year":"2017","unstructured":"Tunduguru, R., & Thurmond, D. C. (2017). Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out. Frontiers in Endocrinology, 8, 329. https:\/\/doi.org\/10.3389\/fendo.2017.00329","journal-title":"Frontiers in Endocrinology"},{"issue":"9","key":"4586_CR7","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1161\/CIRCRESAHA.110.223545","volume":"107","author":"F Giacco","year":"2010","unstructured":"Giacco, F., & Brownlee, M. (2010). Oxidative Stress and Diabetic Complications. Circulation Research, 107(9), 1058\u20131070. https:\/\/doi.org\/10.1161\/CIRCRESAHA.110.223545","journal-title":"Circulation Research"},{"issue":"18","key":"4586_CR8","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1007\/s11434-016-1136-5","volume":"61","author":"Q Zhao","year":"2016","unstructured":"Zhao, Q., Chen, X.-Y., & Martin, C. (2016). Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants. Science Bulletin, 61(18), 1391\u20131398. https:\/\/doi.org\/10.1007\/s11434-016-1136-5","journal-title":"Science Bulletin"},{"issue":"1","key":"4586_CR9","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.joim.2022.09.005","volume":"21","author":"DN Fang","year":"2023","unstructured":"Fang, D. N., Zheng, C. W., & Ma, Y. L. (2023). Effectiveness of Scutellaria baicalensis Georgi root in pregnancy-related diseases: A review. Journal of Integrative Medicine, 21(1), 17\u201325. https:\/\/doi.org\/10.1016\/j.joim.2022.09.005","journal-title":"Journal of Integrative Medicine"},{"issue":"7","key":"4586_CR10","first-page":"3311","volume":"12","author":"G Wang","year":"2020","unstructured":"Wang, G., Lu, J. Q., Ding, Y., Zhang, T., Song, J. H., Long, D., Liang, J., Cheng, X., Si, Z., Qi, G., Jiang, X., & Yang, X. (2020). Baicalin rescues hyperglycemia-induced neural tube defects via targeting on retinoic acid signaling. American Journal of Translational Research, 12(7), 3311\u20133328.","journal-title":"American Journal of Translational Research"},{"issue":"2","key":"4586_CR11","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1038\/s41419-018-0318-2","volume":"9","author":"G Wang","year":"2018","unstructured":"Wang, G., Liang, J., Gao, L. R., Si, Z. P., Zhang, X. T., Liang, G., Yan, Y., Li, K., Cheng, X., Bao, Y., Chuai, M., Chen, L. G., Lu, D. X., & Yang, X. (2018). Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system. Cell Death & Disease, 9(2), 234. https:\/\/doi.org\/10.1038\/s41419-018-0318-2","journal-title":"Cell Death & Disease"},{"key":"4586_CR12","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.placenta.2022.02.013","volume":"121","author":"J Li","year":"2022","unstructured":"Li, J., Wang, Y., Wu, T., Li, S., Sun, Y. N., & Liu, Z. H. (2022). Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1\/2-NF-\u03baB pathway. Placenta, 121, 126\u2013136. https:\/\/doi.org\/10.1016\/j.placenta.2022.02.013","journal-title":"Placenta"},{"key":"4586_CR13","doi-asserted-by":"publisher","unstructured":"Ma, P., Mao, X.-Y., Li, X.-L., Ma, Y., Qiao, Y.-D., Liu, Z.-Q., \u2026 Cao, Y.-G. (2015). Baicalin alleviates diabetes-associated cognitive deficits via modulation of mitogen-activated protein kinase signaling, brain-derived neurotrophic factor and apoptosis. Molecular Medicine Reports, 12(4), 6377\u20136383. https:\/\/doi.org\/10.3892\/mmr.2015.4219","DOI":"10.3892\/mmr.2015.4219"},{"key":"4586_CR14","doi-asserted-by":"publisher","first-page":"3207","DOI":"10.2147\/DDDT.S319260","volume":"15","author":"L Ma","year":"2021","unstructured":"Ma, L., Wu, F., Shao, Q., Chen, G., Xu, L., & Lu, F. (2021). Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway. Drug Design, Development and Therapy, 15, 3207\u20133221. https:\/\/doi.org\/10.2147\/DDDT.S319260","journal-title":"Drug Design, Development and Therapy"},{"key":"4586_CR15","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2019.7181","author":"M Yang","year":"2019","unstructured":"Yang, M., Kan, L., Wu, L., Zhu, Y., & Wang, Q. (2019). Effect of baicalin on renal function in patients with diabetic nephropathy and its therapeutic mechanism. Experimental and Therapeutic Medicine. https:\/\/doi.org\/10.3892\/etm.2019.7181","journal-title":"Experimental and Therapeutic Medicine"},{"issue":"10","key":"4586_CR16","doi-asserted-by":"publisher","first-page":"7537","DOI":"10.1007\/s11033-020-05816-6","volume":"47","author":"W Xu","year":"2020","unstructured":"Xu, W., Tang, M., Wang, J., & Wang, L. (2020). Anti-inflammatory activities of puerarin in high-fat diet-fed rats with streptozotocin-induced gestational diabetes mellitus. Molecular Biology Reports, 47(10), 7537\u20137546. https:\/\/doi.org\/10.1007\/s11033-020-05816-6","journal-title":"Molecular Biology Reports"},{"issue":"12","key":"4586_CR17","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1016\/j.apjtm.2015.11.002","volume":"8","author":"Z-H Tian","year":"2015","unstructured":"Tian, Z.-H., Miao, F.-T., Zhang, X., Wang, Q.-H., Lei, N., & Guo, L.-C. (2015). Therapeutic effect of okra extract on gestational diabetes mellitus rats induced by streptozotocin. Asian Pacific Journal of Tropical Medicine, 8(12), 1038\u20131042. https:\/\/doi.org\/10.1016\/j.apjtm.2015.11.002","journal-title":"Asian Pacific Journal of Tropical Medicine"},{"issue":"5","key":"4586_CR18","doi-asserted-by":"publisher","first-page":"604","DOI":"10.3923\/ijp.2019.604.615","volume":"15","author":"Y Wang","year":"2019","unstructured":"Wang, Y., Wang, L., Xu, G., & Wei, D. (2019). Hesperidin Exerts the Gestational Diabetes Mellitus via AGEs-RAGE Signalling Pathway. International Journal of Pharmacology, 15(5), 604\u2013615. https:\/\/doi.org\/10.3923\/ijp.2019.604.615","journal-title":"International Journal of Pharmacology"},{"issue":"2","key":"4586_CR19","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1007\/s12013-014-0233-9","volume":"71","author":"X Tang","year":"2015","unstructured":"Tang, X., Qin, Q., Xie, X., & He, P. (2015). Protective Effect of sRAGE on Fetal Development in Pregnant Rats with Gestational Diabetes Mellitus. Cell Biochemistry and Biophysics, 71(2), 549\u2013556. https:\/\/doi.org\/10.1007\/s12013-014-0233-9","journal-title":"Cell Biochemistry and Biophysics"},{"key":"4586_CR20","doi-asserted-by":"publisher","unstructured":"Dai, S., Meng, X., Cai, X., Yuan, C., Zhao, Z., Zhong, L., \u2026 Yin, F. (2021). Therapeutic effect of ursolic acid on fetal development in pregnant rats with gestational diabetes mellitus via AGEs\u2010RAGE signaling pathway. Journal of Food Biochemistry, 45(4). https:\/\/doi.org\/10.1111\/jfbc.13651","DOI":"10.1111\/jfbc.13651"},{"issue":"11","key":"4586_CR21","doi-asserted-by":"publisher","first-page":"3342","DOI":"10.3390\/ijms19113342","volume":"19","author":"J Plows","year":"2018","unstructured":"Plows, J., Stanley, J., Baker, P., Reynolds, C., & Vickers, M. (2018). The Pathophysiology of Gestational Diabetes Mellitus. International Journal of Molecular Sciences, 19(11), 3342. https:\/\/doi.org\/10.3390\/ijms19113342","journal-title":"International Journal of Molecular Sciences"},{"issue":"14","key":"4586_CR22","doi-asserted-by":"publisher","first-page":"5003","DOI":"10.3390\/ijms21145003","volume":"21","author":"EU Alejandro","year":"2020","unstructured":"Alejandro, E. U., Mamerto, T. P., Chung, G., Villavieja, A., Gaus, N. L., Morgan, E., & Pineda-Cortel, M. R. B. (2020). Gestational Diabetes Mellitus: A Harbinger of the Vicious Cycle of Diabetes. International Journal of Molecular Sciences, 21(14), 5003. https:\/\/doi.org\/10.3390\/ijms21145003","journal-title":"International Journal of Molecular Sciences"},{"issue":"4","key":"4586_CR23","doi-asserted-by":"publisher","first-page":"e2875","DOI":"10.1002\/dmrr.2875","volume":"33","author":"K Tanase-Nakao","year":"2017","unstructured":"Tanase-Nakao, K., Arata, N., Kawasaki, M., Yasuhi, I., Sone, H., Mori, R., & Ota, E. (2017). Potential protective effect of lactation against incidence of type 2 diabetes mellitus in women with previous gestational diabetes mellitus: A systematic review and meta-analysis. Diabetes\/Metabolism Research and Reviews, 33(4), e2875. https:\/\/doi.org\/10.1002\/dmrr.2875","journal-title":"Diabetes\/Metabolism Research and Reviews"},{"key":"4586_CR24","doi-asserted-by":"publisher","unstructured":"Kumar, V., Ahmed, D., Verma, A., Anwar, F., Ali, M., & Mujeeb, M. (2013). Umbelliferone \u03b2-D-galactopyranoside from Aegle marmelos (L.) corr. an ethnomedicinal plant with antidiabetic, antihyperlipidemic and antioxidative activity. BMC Complementary and Alternative Medicine, 13(1), 273. https:\/\/doi.org\/10.1186\/1472-6882-13-273","DOI":"10.1186\/1472-6882-13-273"},{"issue":"3","key":"4586_CR25","doi-asserted-by":"publisher","first-page":"272","DOI":"10.5530\/jyp.2015.3.20","volume":"7","author":"VB Menon","year":"2015","unstructured":"Menon, V. B., Kurian, J., Undela, K., Ramesh, M., & Gowdappa, H. B. (2015). Phenytoin Toxicity: A Case Report. Journal of Young Pharmacists, 7(3), 272\u2013275. https:\/\/doi.org\/10.5530\/jyp.2015.3.20","journal-title":"Journal of Young Pharmacists"},{"issue":"2","key":"4586_CR26","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1002\/bdrc.21096","volume":"105","author":"N Vargesson","year":"2015","unstructured":"Vargesson, N. (2015). Thalidomide-induced teratogenesis: History and mechanisms. Birth Defects Research Part C: Embryo Today: Reviews, 105(2), 140\u2013156. https:\/\/doi.org\/10.1002\/bdrc.21096","journal-title":"Birth Defects Research Part C: Embryo Today: Reviews"},{"issue":"2","key":"4586_CR27","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1038\/s41419-017-0135-z","volume":"9","author":"CMO Volpe","year":"2018","unstructured":"Volpe, C. M. O., Villar-Delfino, P. H., dos Anjos, P. M. F., & Nogueira-Machado, J. A. (2018). Cellular death, reactive oxygen species (ROS) and diabetic complications. Cell Death & Disease, 9(2), 119. https:\/\/doi.org\/10.1038\/s41419-017-0135-z","journal-title":"Cell Death & Disease"},{"issue":"11","key":"4586_CR28","doi-asserted-by":"publisher","first-page":"196","DOI":"10.4239\/wjd.v2.i11.196","volume":"2","author":"A Vambergue","year":"2011","unstructured":"Vambergue, A., & Fajardy, I. (2011). Consequences of gestational and pregestational diabetes on placental function and birth weight. World Journal of Diabetes, 2(11), 196. https:\/\/doi.org\/10.4239\/wjd.v2.i11.196","journal-title":"World Journal of Diabetes"},{"issue":"5","key":"4586_CR29","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1002\/jemt.20039","volume":"63","author":"MD Mythili","year":"2004","unstructured":"Mythili, M. D., Vyas, R., Akila, G., & Gunasekaran, S. (2004). Effect of streptozotocin on the ultrastructure of rat pancreatic islets. Microscopy Research and Technique, 63(5), 274\u2013281. https:\/\/doi.org\/10.1002\/jemt.20039","journal-title":"Microscopy Research and Technique"},{"key":"4586_CR30","doi-asserted-by":"publisher","unstructured":"Farid, M. M., Aboul Naser, A. F., Salem, M. M., Ahmed, Y. R., Emam, M., & Hamed, M. A. (2022). Chemical compositions of Commiphora opobalsamum stem bark to alleviate liver complications in streptozotocin-induced diabetes in rats: Role of oxidative stress and DNA damage. Biomarkers, 1\u201313. https:\/\/doi.org\/10.1080\/1354750X.2022.2099015","DOI":"10.1080\/1354750X.2022.2099015"},{"key":"4586_CR31","doi-asserted-by":"publisher","unstructured":"Nurdiana, S., Goh, Y. M., Ahmad, H., Dom, S. M., Syimal\u2019ain Azmi, N., Noor Mohamad Zin, N. S., & Ebrahimi, M. (2017). Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexin. BMC Complementary and Alternative Medicine, 17(1), 290.https:\/\/doi.org\/10.1186\/s12906-017-1762-8","DOI":"10.1186\/s12906-017-1762-8"},{"key":"4586_CR32","doi-asserted-by":"publisher","unstructured":"Smirnov, A. V., Snigur, G. L., & Voronkov, M. P. (2012). Pancreatic Islet Beta-Cell Apoptosis in Experimental Diabetes Mellitus. In T. Ntuli (Ed.), Apoptosis and Medicine. InTech. https:\/\/doi.org\/10.5772\/51411","DOI":"10.5772\/51411"},{"key":"4586_CR33","doi-asserted-by":"publisher","unstructured":"Chen, G., Chen, X., Niu, C., Huang, X., An, N., Sun, J., \u2026 Jin, L. (2019). Baicalin alleviates hyperglycemia-induced endothelial impairment via Nrf2. Journal of Endocrinology, 240(1), 81\u201398. https:\/\/doi.org\/10.1530\/JOE-18-0457","DOI":"10.1530\/JOE-18-0457"},{"issue":"9","key":"4586_CR34","doi-asserted-by":"publisher","first-page":"519","DOI":"10.5483\/BMBRep.2015.48.9.017","volume":"48","author":"S-K Ku","year":"2015","unstructured":"Ku, S.-K., & Bae, J.-S. (2015). Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. BMB Reports, 48(9), 519\u2013524. https:\/\/doi.org\/10.5483\/BMBRep.2015.48.9.017","journal-title":"BMB Reports"},{"key":"4586_CR35","doi-asserted-by":"publisher","unstructured":"Tsalamandris, S., Antonopoulos, A. S., Oikonomou, E., Papamikroulis, G.-A., Vogiatzi, G., Papaioannou, S., \u2026 Tousoulis, D. (2019). The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives. European Cardiology Review, 14(1), 50\u201359. https:\/\/doi.org\/10.15420\/ecr.2018.33.1","DOI":"10.15420\/ecr.2018.33.1"},{"issue":"1","key":"4586_CR36","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/s12958-019-0522-7","volume":"17","author":"R Zhang","year":"2019","unstructured":"Zhang, R., Zhang, X., Xing, B., Zhao, J., Zhang, P., Shi, D., & Yang, F. (2019). Astragaloside IV attenuates gestational diabetes mellitus via targeting NLRP3 inflammasome in genetic mice. Reproductive Biology and Endocrinology, 17(1), 77. https:\/\/doi.org\/10.1186\/s12958-019-0522-7","journal-title":"Reproductive Biology and Endocrinology"},{"key":"4586_CR37","doi-asserted-by":"publisher","unstructured":"Fang, P., Yu, M., Zhang, L., Wan, D., Shi, M., Zhu, Y., \u2026 Zhang, Z. (2017). Baicalin against obesity and insulin resistance through activation of AKT\/AS160\/GLUT4 pathway. Molecular and Cellular Endocrinology, 448, 77\u201386. https:\/\/doi.org\/10.1016\/j.mce.2017.03.027","DOI":"10.1016\/j.mce.2017.03.027"},{"issue":"1","key":"4586_CR38","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.cmet.2012.11.012","volume":"17","author":"C Rask-Madsen","year":"2013","unstructured":"Rask-Madsen, C., & King, G. L. (2013). Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors. Cell Metabolism, 17(1), 20\u201333. https:\/\/doi.org\/10.1016\/j.cmet.2012.11.012","journal-title":"Cell Metabolism"},{"key":"4586_CR39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2014\/801269","volume":"2014","author":"SZ Safi","year":"2014","unstructured":"Safi, S. Z., Qvist, R., Kumar, S., Batumalaie, K., & Ismail, I. S. B. (2014). Molecular Mechanisms of Diabetic Retinopathy, General Preventive Strategies, and Novel Therapeutic Targets. BioMed Research International, 2014, 1\u201318. https:\/\/doi.org\/10.1155\/2014\/801269","journal-title":"BioMed Research International"},{"issue":"8","key":"4586_CR40","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.3390\/cells11081312","volume":"11","author":"A Twarda-Clapa","year":"2022","unstructured":"Twarda-Clapa, A., Olczak, A., Bia\u0142kowska, A. M., & Kozio\u0142kiewicz, M. (2022). Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs. Cells, 11(8), 1312. https:\/\/doi.org\/10.3390\/cells11081312","journal-title":"Cells"},{"key":"4586_CR41","doi-asserted-by":"publisher","first-page":"e9","DOI":"10.1017\/S146239940900101X","volume":"11","author":"SF Yan","year":"2009","unstructured":"Yan, S. F., Ramasamy, R., & Schmidt, A. M. (2009). The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease. Expert Reviews in Molecular Medicine, 11, e9. https:\/\/doi.org\/10.1017\/S146239940900101X","journal-title":"Expert Reviews in Molecular Medicine"},{"issue":"1","key":"4586_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4196\/kjpp.2014.18.1.1","volume":"18","author":"VP Singh","year":"2014","unstructured":"Singh, V. P., Bali, A., Singh, N., & Jaggi, A. S. (2014). Advanced Glycation End Products and Diabetic Complications. The Korean Journal of Physiology & Pharmacology, 18(1), 1. https:\/\/doi.org\/10.4196\/kjpp.2014.18.1.1","journal-title":"The Korean Journal of Physiology & Pharmacology"},{"issue":"4","key":"4586_CR43","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1007\/s00726-010-0773-2","volume":"42","author":"R Ramasamy","year":"2012","unstructured":"Ramasamy, R., Yan, S. F., & Schmidt, A. M. (2012). Advanced glycation endproducts: From precursors to RAGE: Round and round we go. Amino Acids, 42(4), 1151\u20131161. https:\/\/doi.org\/10.1007\/s00726-010-0773-2","journal-title":"Amino Acids"},{"key":"4586_CR44","doi-asserted-by":"publisher","unstructured":"AL-Ishaq, Abotaleb, Kubatka, Kajo, & B\u00fcsselberg. (2019). Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels. Biomolecules, 9(9), 430.https:\/\/doi.org\/10.3390\/biom9090430","DOI":"10.3390\/biom9090430"},{"issue":"1","key":"4586_CR45","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1159\/000492159","volume":"9","author":"J Shi","year":"2019","unstructured":"Shi, J., Wu, G., Zou, X., & Jiang, K. (2019). Enteral Baicalin, a Flavone Glycoside, Reduces Indicators of Cardiac Surgery-Associated Acute Kidney Injury in Rats. Cardiorenal Medicine, 9(1), 31\u201340. https:\/\/doi.org\/10.1159\/000492159","journal-title":"Cardiorenal Medicine"},{"issue":"3","key":"4586_CR46","first-page":"964","volume":"17","author":"Z Vafaei-Pour","year":"2018","unstructured":"Vafaei-Pour, Z., Shokrzadeh, M., Jahani, M., & Shaki, F. (2018). Embryo-Protective Effects of Cerium Oxide Nanoparticles against Gestational Diabetes in Mice. Iranian journal of pharmaceutical research: IJPR, 17(3), 964\u2013975.","journal-title":"Iranian journal of pharmaceutical research: IJPR"},{"issue":"3","key":"4586_CR47","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1016\/j.ajog.2003.09.025","volume":"190","author":"K Holemans","year":"2004","unstructured":"Holemans, K., Caluwaerts, S., Poston, L., & Van Assche, F. A. (2004). Diet-induced obesity in the rat: A model for gestational diabetes mellitus. American Journal of Obstetrics and Gynecology, 190(3), 858\u2013865. https:\/\/doi.org\/10.1016\/j.ajog.2003.09.025","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"4586_CR48","doi-asserted-by":"publisher","unstructured":"Liu, B., Xu, Y., Voss, C., Qiu, F., Zhao, M., Liu, Y., \u2026 Wang, Z. (2012). Altered Protein Expression in Gestational Diabetes Mellitus Placentas Provides Insight into Insulin Resistance and Coagulation\/Fibrinolysis Pathways. PLoS One, 7(9), e44701. https:\/\/doi.org\/10.1371\/journal.pone.0044701","DOI":"10.1371\/journal.pone.0044701"},{"issue":"1","key":"4586_CR49","doi-asserted-by":"publisher","first-page":"194","DOI":"10.3390\/biom5010194","volume":"5","author":"K Nowotny","year":"2015","unstructured":"Nowotny, K., Jung, T., H\u00f6hn, A., Weber, D., & Grune, T. (2015). Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus. Biomolecules, 5(1), 194\u2013222. https:\/\/doi.org\/10.3390\/biom5010194","journal-title":"Biomolecules"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-023-04586-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12010-023-04586-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-023-04586-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T11:13:25Z","timestamp":1708341205000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12010-023-04586-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,12]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["4586"],"URL":"https:\/\/doi.org\/10.1007\/s12010-023-04586-8","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,12]]},"assertion":[{"value":"26 May 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"The authors have the consent to participate.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"The authors have the consent to publish.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publish"}},{"value":"The authors declare no competing of interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}