{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T09:53:06Z","timestamp":1774691586610,"version":"3.50.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s12010-026-05600-5","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T09:20:05Z","timestamp":1769678405000},"page":"2767-2792","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unveiling the Hydrocarbon-Degrading Potential of Bacillus Cereus BY-16: A Multi-Omics, Proteomics and Biogenic Nanoparticle Profiling-Driven Investigation"],"prefix":"10.1007","volume":"198","author":[{"given":"Parvaze Ahmad","family":"Wani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas Ahmad","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Unzilla","family":"Amin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bashir Ahmad","family":"Ganai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohd Sajjad Ahmad","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rubiya","family":"Dar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaffar","family":"Bashir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saba","family":"Wani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"5600_CR1","doi-asserted-by":"publisher","first-page":"105508","DOI":"10.1016\/j.ibiod.2022.105508","volume":"175","author":"KI Ehiosun","year":"2022","unstructured":"Ehiosun, K. I., Godin, S., Urios, L., Lobinski, R., & Grimaud, R. (2022). Degradation of long-chain alkanes through biofilm formation by bacteria isolated from oil polluted soil. International Biodeterioration & Biodegradation, 175, Article 105508.","journal-title":"International Biodeterioration & Biodegradation"},{"key":"5600_CR2","doi-asserted-by":"publisher","first-page":"120409","DOI":"10.1016\/j.envpol.2022.120409","volume":"315","author":"P Giraldez","year":"2022","unstructured":"Giraldez, P., Aboal, J. R., Fernandez, A., Di Guardo, A., & Terzaghi, E. (2022). Plant-air partition coefficients for thirteen urban conifer tree species: Estimating the best gas and particulate matter associated PAH removers. Environmental Pollution, 315, Article 120409.","journal-title":"Environmental Pollution"},{"key":"5600_CR3","doi-asserted-by":"publisher","DOI":"10.1080\/0972060X.2024.2338154","author":"PA Wani","year":"2024","unstructured":"Wani, P. A., Grace, A. T., Omobolanle, A. W., Ama, B. M., Ishaq, M. A., Jan, T., Wani, U., Jan, N., & Oluwaseun, O. I. (2024). Anti-microbial, anti-diabetic and anti-quorum sensing activity of the essential oil of Dialium guineense Willd. grown in South-West Nigeria. Journal of Essential Oil Bearing Plants. https:\/\/doi.org\/10.1080\/0972060X.2024.2338154","journal-title":"Journal of Essential Oil Bearing Plants"},{"key":"5600_CR4","first-page":"39","volume":"9","author":"M Wang","year":"2021","unstructured":"Wang, M., Garrido-Sanz, D., Sansegundo-Lobato, P., Redondo-Nieto, M., Conlon, R., Martin, M., Mali, R., Liu, X., Dowling, D. N., Rivilla, R., et al. (2021). Soil microbiome structure and function in ecopiles used to remediate petroleum-contaminated soil. Frontiers in Environmental Science, 9, Article 39.","journal-title":"Frontiers in Environmental Science"},{"key":"5600_CR5","first-page":"17250","volume":"29","author":"A Bharti","year":"2022","unstructured":"Bharti, A., Shukla, R., & Chandra, R. (2022). Effect of hydrocarbon stress on growth and antioxidant responses of chickpea (Cicer arietinum) and role of plant growth promoting rhizobacteria. Environmental Science and Pollution Research, 29, 17250\u201317264.","journal-title":"Environmental Science and Pollution Research"},{"key":"5600_CR6","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.jenvman.2019.04.019","volume":"241","author":"CM Quintella","year":"2019","unstructured":"Quintella, C. M., Mata, A. M. T., & Lima, L. C. P. (2019). Overview of bioremediation with technology assessment and emphasis on fungal bioremediation of oil contaminated soils. Journal of Environmental Management, 241, 156\u2013166.","journal-title":"Journal of Environmental Management"},{"issue":"2","key":"5600_CR7","doi-asserted-by":"publisher","first-page":"375","DOI":"10.3390\/w15020375","volume":"15","author":"E Pandolfo","year":"2023","unstructured":"Pandolfo, E., Caracciolo, A. B., & Rolando, L. (2023). Recent advances in bacterial degradation of hydrocarbons. Water, 15(2), Article 375.","journal-title":"Water"},{"key":"5600_CR8","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.ecoenv.2019.02.071","volume":"175","author":"N Bourguignona","year":"2019","unstructured":"Bourguignona, N., Irazustab, V., Isaacd, P., Est\u00e9veze, C., Maizelf, D., & Ferrero, M. A. (2019). Identification of proteins induced by polycyclic aromatic hydrocarbon and proposal of the phenanthrene catabolic pathway in Amycolatopsis tucumanensis DSM 45259. Ecotoxicology and Environmental Safty, 175, 19\u201328.","journal-title":"Ecotoxicology and Environmental Safty"},{"key":"5600_CR9","doi-asserted-by":"publisher","first-page":"1416516","DOI":"10.3389\/fmicb.2024.1416516","volume":"15","author":"L Fassarella Agnez-Lima","year":"2024","unstructured":"Fassarella Agnez-Lima, L., Vainstein, M. H., & Zhang, X. (2024). Microbial hydrocarbon degradation and bioremediation: From genes to pathways. Frontiers Microbiology, 15, Article 1416516.","journal-title":"Frontiers Microbiology"},{"key":"5600_CR10","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.biortech.2016.10.006","volume":"222","author":"SJ Varjani","year":"2016","unstructured":"Varjani, S. J., & Upasani, V. N. (2016). Biodegradation of petroleum hydrocarbons by oleophilic strain of Pseudomonas aeruginosa NCIM 5514. Bioresource Technology, 222, 195\u2013201.","journal-title":"Bioresource Technology"},{"issue":"3","key":"5600_CR11","first-page":"145","volume":"12","author":"S Velamakanni","year":"2024","unstructured":"Velamakanni, S., Yao, Y., & Gutmann, D. A. (2024). Efflux mediated detoxification of xenobiotic compounds in microorganisms. Journal of Microbiological Research, 12(3), 145\u2013160.","journal-title":"Journal of Microbiological Research"},{"key":"5600_CR12","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1007\/s10534-024-00582-5","volume":"37","author":"P Vainberg","year":"2024","unstructured":"Vainberg, P., & Harrison, M. T. (2024). Cadmium transport by mammalian ATP binding cassette transporters. Biometals, 37, 697\u2013719.","journal-title":"Biometals"},{"issue":"6","key":"5600_CR13","first-page":"69","volume":"8","author":"M Veerapagu","year":"2019","unstructured":"Veerapagu, M., Jeya, K. R., Kalaivani, R., Jeyanthi, K. A., & Geethanjali, S. (2019). Screening of hydrocarbon degrading bacteria isolated from oil contaminated soil. Journal of pharmaceutical Innovation, 8(6), 69\u201372.","journal-title":"Journal of pharmaceutical Innovation"},{"key":"5600_CR14","doi-asserted-by":"publisher","first-page":"e00747","DOI":"10.1016\/j.btre.2022.e00747","volume":"35","author":"ZA Disi","year":"2022","unstructured":"Disi, Z. A., Attia, E., Ahmad, M. I., & Zouari, N. (2022). Immobilization of heavy metals by microbially induced carbonate precipitation using hydrocarbon-degrading ureolytic bacteria. Biotechnology Reports, 35, Article e00747.","journal-title":"Biotechnology Reports"},{"key":"5600_CR15","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.micpath.2017.09.019","volume":"111","author":"S Saleem","year":"2017","unstructured":"Saleem, S., Ahmed, B., Khan, M. S., Al-Shaeri, M., & Musarrat, J. (2017). Inhibition of growth and biofilm formation of clinical bacterial isolates by NiO nanoparticles synthesized from Eucalyptus globules plants. Microbial Pathogenicity, 111, 375\u2013387.","journal-title":"Microbial Pathogenicity"},{"key":"5600_CR16","doi-asserted-by":"publisher","DOI":"10.1002\/jobm.202300352","author":"PA Wani","year":"2023","unstructured":"Wani, P. A., Olusebi, Y. K., & Rilwan, B. A. (2023a). Remediation of hydrocarbons and metals by hydrocarbon utilizing Pseudomonas taiwanensis YSA-17 isolated from soil contaminated with petroleum. Journalof Basic Microbiology. https:\/\/doi.org\/10.1002\/jobm.202300352","journal-title":"Journalof Basic Microbiology"},{"key":"5600_CR17","doi-asserted-by":"publisher","first-page":"106525","DOI":"10.1016\/j.fbio.2025.106525","volume":"68","author":"G Wang","year":"2025","unstructured":"Wang, G., Wang, Y., Chen, Y., & Ma, F. (2025). Lipopeptide biosurfactants of Pseudomonas fragi showed intraspecific specificity to their biological traits. Food Bioscience, 68, Article 106525.","journal-title":"Food Bioscience"},{"key":"5600_CR18","doi-asserted-by":"publisher","first-page":"1305731","DOI":"10.3389\/fmicb.2023.1305731","volume":"14","author":"J Xu","year":"2023","unstructured":"Xu, J., Wang, L., Lv, W., Song, X., & Wu, X. (2023). Metabolic profiling of petroleum degrading microbial communities incubated under high pressure conditions. Frontiers in Microbiology, 14, Article 1305731.","journal-title":"Frontiers in Microbiology"},{"issue":"17","key":"5600_CR19","doi-asserted-by":"publisher","first-page":"4132","DOI":"10.3390\/molecules29174132","volume":"29","author":"R Calegri-Santos","year":"2024","unstructured":"Calegri-Santos, R., Diogo, R. A., Fontana, J. D., & Bonfim, T. M. B. (2024). Iconic liquids toward enhanced carotenoid extraction from bacterial cells originally isolated from oil-contaminated soils. Molecules, 29(17), Article 4132.","journal-title":"Molecules"},{"issue":"1","key":"5600_CR20","first-page":"125509","volume":"367","author":"CF Fernandes","year":"2024","unstructured":"Fernandes, C. F., Ludice, T. N. S., Benzerra, N. V., & Pontes, A. N. (2024). Biodegradation of oil derived hydrocarbons by marineactinobacteria: A systematic review. Environmental Pollution, 367(1), Article 125509.","journal-title":"Environmental Pollution"},{"issue":"12","key":"5600_CR21","doi-asserted-by":"publisher","first-page":"3290","DOI":"10.3390\/nano11123290","volume":"11","author":"MS Samuel","year":"2021","unstructured":"Samuel, M. S., Datta, S., Chandrasekar, N., Balaji, R., Selvarajan, E., & Vuppala, S. (2021). Biogenic synthesis of iron oxide nanoparticles using Enterococcus faecalis: Adsorption of hexavalent chromium from aqueous solution and in vitro cytotoxicity analysis. Nanomaterials, 11(12), Article 3290.","journal-title":"Nanomaterials"},{"key":"5600_CR22","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1038\/s41598-024-84974-0","volume":"15","author":"S Ashrafi-Saiedlou","year":"2025","unstructured":"Ashrafi-Saiedlou, S., Rasouli-Sadaghiani, M. H., Fattahi, M., & Ghosta, Y. (2025). Biosynthesis and characterization of iron oxide nanoparticles fabricated using cell free supernatant of Pseudomonas fluorescens for antibacterial, antifungal, antioxidant and photocatalytic applications. Scientific Reports, 15, Article 1018.","journal-title":"Scientific Reports"},{"key":"5600_CR23","first-page":"106390","volume":"219","author":"Y Dong","year":"2022","unstructured":"Dong, Y., Li, Q., Li, Y., et al. (2022). Antibacterial kaolinite based nanocomposites for drug delivery applications. Applied Clay Science, 219, 106390.","journal-title":"Applied Clay Science"},{"issue":"6","key":"5600_CR24","doi-asserted-by":"publisher","first-page":"e00824-20","DOI":"10.1128\/mSystems.00824-20","volume":"5","author":"A Moreno-Ulloa","year":"2020","unstructured":"Moreno-Ulloa, A., Sicairos Diaz, V., Tejeda-Mora, J. A., Macias Contreras, M. I., Castillo, F. D., Guerrero, A., Gonzalez Sanchez, R., Mendoza-Porras, O., Vazquez Duhalt, R., & Licea-Navarro, A. (2020). Chemical profiling provides insights into the metabolic machinery of hydrocarbon degrading deep-sea microbes. mSystems, 5(6), Article e00824-20.","journal-title":"mSystems"},{"issue":"11","key":"5600_CR25","doi-asserted-by":"publisher","first-page":"2544","DOI":"10.3390\/molecules29112544","volume":"29","author":"S Dini","year":"2024","unstructured":"Dini, S., Bekhit, A. E. D. A., Roohinejad, S., Vale, J. M., & Agyei, D. (2024). The physicochemical and functional properties of biosurfactants: A review. Molecules, 29(11), Article 2544.","journal-title":"Molecules"},{"key":"5600_CR26","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1016\/j.biortech.2015.06.043","volume":"192","author":"MV Reddy","year":"2015","unstructured":"Reddy, M. V., Mawatari, Y., Yajima, Y., Seki, C., Hoshino, T., & Chang, Y. (2015). Poly-3-hydroxybutyrate (PHB) production from alkylphenols, mono and poly-aromatic hydrocarbons using Bacillus sp. CYR1: A new strategy for wealth from waste. Bioresource Technology, 192, 711\u2013717.","journal-title":"Bioresource Technology"},{"key":"5600_CR27","doi-asserted-by":"publisher","first-page":"108803","DOI":"10.1016\/j.bej.2022.108803","volume":"191","author":"S Qin","year":"2023","unstructured":"Qin, S., Liu, X., Lv, W., Hu, J., Huang, X., & Zhao, L. (2023). The mechanism of degradation polycyclic aromatic hydrocarbons by magnetic biogenic manganese oxides. Biochemical Engineering Journal, 191, Article 108803.","journal-title":"Biochemical Engineering Journal"},{"key":"5600_CR28","doi-asserted-by":"publisher","first-page":"14060","DOI":"10.1039\/C9RA10371F","volume":"10","author":"A Medic","year":"2020","unstructured":"Medic, A., Marija Ljesevic, M. J., Inui, H., Beskoski, V., Kojic, I., Stojanovic, K., & Karadzi, I. (2020). Efficient biodegradation of petroleum n-alkanes and polycyclic aromatic hydrocarbons by polyextremophilic Pseudomonas aeruginosa san ai with multidegradative capacity. RSC Advances, 10, Article 14060.","journal-title":"RSC Advances"},{"issue":"3","key":"5600_CR29","first-page":"889","volume":"108","author":"Y Wang","year":"2024","unstructured":"Wang, Y., & Li, J. (2024). Bacterial transformation and degradation of polycyclic aromatic hydrocarbons and formation of cyclic intermediates. Applied Microbiology and Biotechnology, 108(3), 889\u2013903.","journal-title":"Applied Microbiology and Biotechnology"},{"issue":"1","key":"5600_CR30","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1080\/10889868.2021.1989371","volume":"27","author":"PA Wani","year":"2023","unstructured":"Wani, P. A., Rafi, N., Wani, U., & Bilikis, H. A. (2023b). Simultaneous bioremediation of heavy metals and biodegradation of hydrocarbons by metal resistant Brevibacillus parabrevis OZF5 improves plant growth promotion. Bioremediation Journal, 27(1), 20\u201331.","journal-title":"Bioremediation Journal"},{"key":"5600_CR31","doi-asserted-by":"crossref","unstructured":"Kebede, A., Tafese, T., Abda, E. M., Kamaraj, M., & Assefa, F. (2021). Factors influencing the bacterial bioremediation of hydrocarbon contaminants in soil: Mechanisms and impacts. Journal of Chemistry, 9823362.","DOI":"10.1155\/2021\/9823362"},{"key":"5600_CR32","doi-asserted-by":"publisher","first-page":"14402","DOI":"10.1016\/j.chemosphere.2024.144020","volume":"370","author":"E Gonzalez-Morales","year":"2025","unstructured":"Gonzalez-Morales, E., Peula-Ruiz, E., Newman-Portela, A. M., L\u00b4opez-Tercero, L., Medina-Castillo, A. L., Lopez-Lopez, M. T., Merroun, M. L., & Ruiz-Fresneda, M. A. (2025). Enhancing Se(IV) bioremediation efficiency via immobilization of filamentous fungi and yeasts in eco-friendly alginate bead hydrogels. Chemosphere, 370, Article 14402.","journal-title":"Chemosphere"},{"key":"5600_CR33","first-page":"194","volume":"51","author":"ZA Al Disi","year":"2017","unstructured":"Al Disi, Z. A., Jaoua, S., Bontognali, T. R. R., Attia, E. S. M., Al-Kuwari, H. A. A. S., & Zouari, N. (2017). Microbial enhanced hydrocarbon degradation and its visualization using TEM in contaminated soil. Journal of Environmental Science, 51, 194\u2013203.","journal-title":"Journal of Environmental Science"},{"issue":"2","key":"5600_CR34","first-page":"477","volume":"194","author":"TA Plekhanova","year":"2024","unstructured":"Plekhanova, T. A., Ivanov, A. V., Morozov, N. S., & Egorova, K. S. (2024). Microbial encapsulation strategies for enhanced biocatalysis of hydrophobic substrates: Advances and perspectives. Applied Biochemistry and Biotechnology, 194(2), 477\u2013491.","journal-title":"Applied Biochemistry and Biotechnology"},{"issue":"1","key":"5600_CR35","doi-asserted-by":"publisher","first-page":"65","DOI":"10.33073\/pjm-2024-012","volume":"73","author":"H Hussain","year":"2024","unstructured":"Hussain, H., Ashraf, M. A., Ali, I., Imran, A., & Iqbal, M. (2024). Molecular and metabolic characterization of petroleum hydrocarbons degrading Bacillus cereus. Polish Journal of Microbiology, 73(1), 65\u201374.","journal-title":"Polish Journal of Microbiology"},{"key":"5600_CR36","first-page":"100138","volume":"9","author":"IS Ogunyemi","year":"2025","unstructured":"Ogunyemi, I. S., Atolani, O., & Olutunji, T. L. (2025). Biodegradation potential of Pseudomonas synxantha rhizo-25 on spent Tandemol lubricant using multi-omics approaches. Cleaner Waste Systems, 9, Article 100138.","journal-title":"Cleaner Waste Systems"},{"issue":"4","key":"5600_CR37","doi-asserted-by":"publisher","first-page":"e01238-16","DOI":"10.1128\/mBio.01238-16","volume":"7","author":"J Van der Heijden","year":"2016","unstructured":"Van der Heijden, J., Reynolds, L., Deng, W., Scholz, R., Imani, K., Foster, L. J., Duong, F., & Finlay, B. B. (2016). Salmonella rapidly regulates membrane permeability to survive oxidative stress. mBio, 7(4), Article e01238-16.","journal-title":"mBio"},{"key":"5600_CR38","doi-asserted-by":"publisher","first-page":"552969","DOI":"10.3389\/fpls.2020.552969","volume":"11","author":"J Dumanovic","year":"2021","unstructured":"Dumanovic, J., Nepovimova, E., Natic, M., Kuca, K., & Jacevic, V. (2021). The significance of reactive oxygen species and antioxidant defense system in plants: A concise overview. Frontiers in Plant Science, 11, Article 552969.","journal-title":"Frontiers in Plant Science"},{"issue":"5","key":"5600_CR39","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1111\/1462-2920.14956","volume":"22","author":"BH Gregson","year":"2020","unstructured":"Gregson, B. H., Metodieva, G., Metodiev, M. V., Golyshin, P., & McKew, B. A. (2020). Protein expression in the obligate hydrocarbon degrading psychrophile Oleispira antarctica RB-8 during alkane degradation and cold tolerance. Environmental Microbiology, 22(5), 1870\u20131883.","journal-title":"Environmental Microbiology"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05600-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12010-026-05600-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05600-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T09:12:45Z","timestamp":1774689165000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12010-026-05600-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,29]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["5600"],"URL":"https:\/\/doi.org\/10.1007\/s12010-026-05600-5","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,29]]},"assertion":[{"value":"14 January 2026","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2026","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"All authors provided informed consent to participate in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Consent for publication of this article was obtained from all the authors.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publish"}},{"value":"Authors declare that there are no conflicts of interest associated with this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Authors alone are responsible for the content of this work.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}