{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:13:47Z","timestamp":1777950827811,"version":"3.51.4"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Scientific Research Foundation of Changzhou University","award":["ZMF22020021"],"award-info":[{"award-number":["ZMF22020021"]}]},{"name":"State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology","award":["CRE-24-C004"],"award-info":[{"award-number":["CRE-24-C004"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1007\/s12010-026-05638-5","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T11:22:29Z","timestamp":1773141749000},"page":"4013-4033","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Simultaneous Production of Bioethanol and Monascus Pigments: a Strategy of Trace Element Supplementation for Monascus purpureus Fermentation"],"prefix":"10.1007","volume":"198","author":[{"given":"Jianqi","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinji","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxiao","family":"Gan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8602-717X","authenticated-orcid":false,"given":"Jie","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"issue":"1","key":"5638_CR1","doi-asserted-by":"publisher","DOI":"10.1186\/s40643-023-00717-5","volume":"11","author":"C Wang","year":"2024","unstructured":"Wang, C., Chang, D., Zhang, Q., & Yu, Z. (2024). Enhanced bioethanol production by evolved Escherichia coli LGE2-H in a microbial electrolysis cell system. Bioresources and Bioprocessing, 11(1), Article 4. https:\/\/doi.org\/10.1186\/s40643-023-00717-5","journal-title":"Bioresources and Bioprocessing"},{"key":"5638_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2024.130420","volume":"396","author":"L Liu","year":"2024","unstructured":"Liu, L., Zhou, Z., Gong, G., Wu, B., Todhanakasem, T., Li, J., Zhuang, Y., & He, M. (2024). Economic co-production of cellulosic ethanol and microalgal biomass through efficient fixation of fermentation carbon dioxide. Bioresource Technology, 396, Article 130420. https:\/\/doi.org\/10.1016\/j.biortech.2024.130420","journal-title":"Bioresource Technology"},{"issue":"5","key":"5638_CR3","doi-asserted-by":"publisher","first-page":"3286","DOI":"10.1016\/j.jbiotec.2023.11.002","volume":"16","author":"A Amore","year":"2012","unstructured":"Amore, A., & Faraco, V. (2012). Potential of fungi as category I consolidated bioprocessing organisms for cellulosic ethanol production. Renewable and Sustainable Energy Reviews, 16(5), 3286\u20133301. https:\/\/doi.org\/10.1016\/j.jbiotec.2023.11.002","journal-title":"Renewable and Sustainable Energy Reviews"},{"issue":"26","key":"5638_CR4","doi-asserted-by":"publisher","first-page":"7139","DOI":"10.1080\/10408398.2021.1935443","volume":"62","author":"J He","year":"2022","unstructured":"He, J., Jia, M., Li, W., Deng, J., Ren, J., Luo, F., Bai, J., & Liu, J. (2022). Toward improvements for enhancement the productivity and color value of Monascus pigments: A critical review with recent updates. Critical Reviews in Food Science and Nutrition, 62(26), 7139\u20137153. https:\/\/doi.org\/10.1080\/10408398.2021.1935443","journal-title":"Critical Reviews in Food Science and Nutrition"},{"key":"5638_CR5","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.biortech.2016.09.074","volume":"221","author":"RB Nair","year":"2016","unstructured":"Nair, R. B., & Taherzadeh, M. J. (2016). Valorization of sugar-to-ethanol process waste vinasse: A novel biorefinery approach using edible ascomycetes filamentous fungi. Bioresource Technology, 221, 469\u2013476. https:\/\/doi.org\/10.1016\/j.biortech.2016.09.074","journal-title":"Bioresource Technology"},{"key":"5638_CR6","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.biortech.2016.03.018","volume":"215","author":"JA Ferreira","year":"2016","unstructured":"Ferreira, J. A., Mahboubi, A., Lennartsson, P. R., & Taherzadeh, M. J. (2016). Waste biorefineries using filamentous ascomycetes fungi: Present status and future prospects. Bioresource Technology, 215, 334\u2013345. https:\/\/doi.org\/10.1016\/j.biortech.2016.03.018","journal-title":"Bioresource Technology"},{"key":"5638_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jbiotec.2023.11.002","volume":"379","author":"M Jawad","year":"2024","unstructured":"Jawad, M., Wang, H., Wu, Y., Rehman, O., Song, Y., Xu, R., Zhang, Q., Gao, H., & Xue, C. (2024). Lignocellulosic ethanol and butanol production by Saccharomyces cerevisiae and Clostridium beijerinckii co-culture using non-detoxified corn stover hydrolysate. Journal of Biotechnology, 379, 1\u20135. https:\/\/doi.org\/10.1016\/j.jbiotec.2023.11.002","journal-title":"Journal of Biotechnology"},{"issue":"1","key":"5638_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/fermentation5010021","volume":"5","author":"S Horisawa","year":"2019","unstructured":"Horisawa, S., Inoue, A., & Yamanaka, Y. (2019). Direct ethanol production from lignocellulosic materials by mixed culture of wood rot fungi Schizophyllum commune, Bjerkandera adusta, and Fomitopsis palustris. Fermentation, 5(1), Article 29. https:\/\/doi.org\/10.3390\/fermentation5010021","journal-title":"Fermentation"},{"issue":"1","key":"5638_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.134524","volume":"278","author":"P Liu","year":"2024","unstructured":"Liu, P., Wang, Y., Kang, H., Wang, Y., Yu, H., Peng, H., He, B., Xu, C., Jia, K. Z., Liu, S., Xia, T., & Peng, L. (2024). Upgraded cellulose and xylan digestions for synergistic enhancements of biomass enzymatic saccharification and bioethanol conversion using engineered Trichoderma reesei strains overproducing mushroom LeGH7 enzyme. International Journal of Biological Macromolecules, 278(1), Article 134524. https:\/\/doi.org\/10.1016\/j.ijbiomac.2024.134524","journal-title":"International Journal of Biological Macromolecules"},{"key":"5638_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2024.131002","volume":"406","author":"S Chang","year":"2024","unstructured":"Chang, S., Yun, C., Yang, B., Duan, J., Chen, T., Liu, L., Li, B., Guo, S., & Zhang, S. (2024). Comprehensive reutilization of Glycyrrhiza uralensis residue by extrusion-biological pretreatment for coproduction of flavonoids, cellulase, and ethanol. Bioresource Technology, 406, Article 131002. https:\/\/doi.org\/10.1016\/j.biortech.2024.131002","journal-title":"Bioresource Technology"},{"issue":"1","key":"5638_CR11","doi-asserted-by":"publisher","DOI":"10.1186\/s13068-024-02511-7","volume":"17","author":"X Yi","year":"2024","unstructured":"Yi, X., Han, J., Xu, X., Wang, Y., Zhang, M., Zhu, J., & He, Y. (2024). Taurine-mediated gene transcription and cell membrane permeability reinforced co-production of bioethanol and Monascus azaphilone pigments for a newly isolated Monascus purpureus. Biotechnology for Biofuels and Bioproducts, 17(1), Article 59. https:\/\/doi.org\/10.1186\/s13068-024-02511-7","journal-title":"Biotechnology for Biofuels and Bioproducts"},{"issue":"35","key":"5638_CR12","doi-asserted-by":"publisher","first-page":"21947","DOI":"10.1021\/acs.jafc.5c05969","volume":"73","author":"LQ Xiong","year":"2025","unstructured":"Xiong, L. Q., Li, Y. Z., Liang, S. P., Zhang, C., Hu, W. L., Yang, Q. Q., Moln\u00e1r, I., & Zhang, B. B. (2025). Efficient production of natural yellow azaphilone pigments from Monascus purpureus regulated by microparticle-triggered stress. Journal of Agricultural and Food Chemistry, 73(35), 21947\u201321958. https:\/\/doi.org\/10.1021\/acs.jafc.5c05969","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"5638_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2020.128025","volume":"338","author":"Y Xu","year":"2021","unstructured":"Xu, Y., Wang, X., Liu, X., Li, X., Zhang, C., Li, W., Sun, X., Wang, W., & Sun, B. (2021). Discovery and development of a novel short-chain fatty acid ester synthetic biocatalyst under aqueous phase from Monascus purpureus isolated from Baijiu. Food Chemistry, 338, Article 128025. https:\/\/doi.org\/10.1016\/j.foodchem.2020.128025","journal-title":"Food Chemistry"},{"key":"5638_CR14","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.862080","volume":"13","author":"HEF Abdel-Raheam","year":"2022","unstructured":"Abdel-Raheam, H. E. F., Alrumman, S. A., Gadow, S. I., El-Sayed, M. H., Hikal, D. M., Hesham, A. E., & Ali, M. M. A. (2022). Optimization of Monascus purpureus for natural food pigments production on potato wastes and their application in ice lolly. Frontiers in Microbiology, 13, Article 862080. https:\/\/doi.org\/10.3389\/fmicb.2022.862080","journal-title":"Frontiers in Microbiology"},{"key":"5638_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.921540","volume":"13","author":"S Yin","year":"2022","unstructured":"Yin, S., Yang, D., Zhu, Y., & Huang, B. (2022). Methionine and S-adenosylmethionine regulate Monascus pigments biosynthesis in Monascus purpureus. Frontiers in Microbiology, 13, Article 921540. https:\/\/doi.org\/10.3389\/fmicb.2022.921540","journal-title":"Frontiers in Microbiology"},{"key":"5638_CR16","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.951266","volume":"13","author":"S Yin","year":"2022","unstructured":"Yin, S., Zhu, Y., Zhang, B., Huang, B., & Jia, R. (2022). Diverse effects of amino acids on Monascus pigments biosynthesis in Monascus purpureus. Frontiers in Microbiology, 13, Article 951266. https:\/\/doi.org\/10.3389\/fmicb.2022.951266","journal-title":"Frontiers in Microbiology"},{"issue":"5","key":"5638_CR17","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1007\/s00253-021-11162-9","volume":"105","author":"HQ Liu","year":"2021","unstructured":"Liu, H. Q., Huang, Z. F., Yang, S. Z., Tian, X. F., & Wu, Z. Q. (2021). Inducing red pigment and inhibiting citrinin production by adding lanthanum (III) ion in Monascus purpureus fermentation. Applied Microbiology and Biotechnology, 105(5), 1905\u20131912. https:\/\/doi.org\/10.1007\/s00253-021-11162-9","journal-title":"Applied Microbiology and Biotechnology"},{"issue":"2","key":"5638_CR18","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1002\/jib.316","volume":"122","author":"R Takeshita","year":"2016","unstructured":"Takeshita, R., Saigusa, N., & Teramoto, Y. (2016). Production and antioxidant activity of alcoholic beverages made from various cereal grains using Monascus purpureus NBRC 5965. Journal of the Institute of Brewing, 122(2), 350\u2013354. https:\/\/doi.org\/10.1002\/jib.316","journal-title":"Journal of the Institute of Brewing"},{"issue":"S2","key":"5638_CR19","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.15159\/AR.18.028","volume":"16","author":"P Adadi","year":"2018","unstructured":"Adadi, P., Kovaleva, E. G., Glukhareva, T. V., & Barakova, N. V. (2018). Production and investigations of antioxidant rich beverage: Utilizing Monascus purpureus IHEM LY2014-0696 and various malts. Agronomy Research, 16(S2), 1312\u20131321. https:\/\/doi.org\/10.15159\/AR.18.028","journal-title":"Agronomy Research"},{"key":"5638_CR20","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.fm.2017.07.019","volume":"69","author":"Z Liu","year":"2018","unstructured":"Liu, Z., Wang, Z., Lv, X., Zhu, X., Chen, L., & Ni, L. (2018). Comparison study of the volatile profiles and microbial communities of Wuyi Qu and Gutian Qu, two major types of traditional fermentation starters of Hong Qu glutinous rice wine. Food Microbiology, 69, 105\u2013115. https:\/\/doi.org\/10.1016\/j.fm.2017.07.019","journal-title":"Food Microbiology"},{"issue":"5","key":"5638_CR21","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1021\/acs.jafc.1c07588","volume":"70","author":"Y Duan","year":"2022","unstructured":"Duan, Y., Du, Y., Yi, Z., Wang, Z., Pei, X., Wei, X., & Li, M. (2022). Systematic metabolic engineering for the production of azaphilones in Monascus purpureus HJ11. Journal of Agricultural and Food Chemistry, 70(5), 1589\u20131600. https:\/\/doi.org\/10.1021\/acs.jafc.1c07588","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"5638_CR22","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1016\/0141-0229(94)90123-6","volume":"16","author":"MH Chen","year":"1994","unstructured":"Chen, M. H., & Johns, M. R. (1994). Effect of carbon source on ethanol and pigment production by Monascus purpureus. Enzyme and Microbial Technology, 16, 584\u2013590. https:\/\/doi.org\/10.1016\/0141-0229(94)90123-6","journal-title":"Enzyme and Microbial Technology"},{"issue":"8","key":"5638_CR23","doi-asserted-by":"publisher","first-page":"2229","DOI":"10.13057\/biodiv\/d200817","volume":"20","author":"D Yudianto","year":"2019","unstructured":"Yudianto, D., Nainggolan, E. A., Millati, R., Hidayat, C., Lennartsson, P., Taherzadeh, M. J., & Niklasson, C. (2019). Bioconversion of pretreated wheat straw to ethanol by Monascus purpureus CBS 109.07 and Fusarium venenatum ATCC 20334 using simultaneous saccharification and fermentation. Biodiversitas, 20(8), 2229\u20132235. https:\/\/doi.org\/10.13057\/biodiv\/d200817","journal-title":"Biodiversitas"},{"key":"5638_CR24","doi-asserted-by":"publisher","unstructured":"Fourest, E., Canal, C., & Roux, J. C. (1994). Improvement of heavy metal biosorption by mycelial dead biomasses (Rhizopus arrhizus, Mucor miehei and Penicillium chrysogenum): pH control and cationic activation. FEMS microbiology reviews, 14(4), 325\u2009\u2013\u200932. https:\/\/doi.org\/10.1111\/j.1574-6976.1994.tb00106.x","DOI":"10.1111\/j.1574-6976.1994.tb00106.x"},{"key":"5638_CR25","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/j.foodchem.2017.08.033","volume":"240","author":"E Xu","year":"2018","unstructured":"Xu, E., Wu, Z., Jiao, A., & Jin, Z. (2018). Effect of exogenous metal ions and mechanical stress on rice processed in thermal-solid enzymatic reaction system related to further alcoholic fermentation efficiency. Food Chemistry, 240, 965\u2013973. https:\/\/doi.org\/10.1016\/j.foodchem.2017.08.033","journal-title":"Food Chemistry"},{"issue":"12","key":"5638_CR26","doi-asserted-by":"publisher","DOI":"10.3390\/biom10121599","volume":"10","author":"A Ciosek","year":"2020","unstructured":"Ciosek, A., Fulara, K., Hrabia, O., Satora, P., & Poreda, A. (2020). Chemical composition of sour beer resulting from supplementation the fermentation medium with magnesium and zinc ions. Biomolecules, 10(12), Article 1599. https:\/\/doi.org\/10.3390\/biom10121599","journal-title":"Biomolecules"},{"issue":"10","key":"5638_CR27","doi-asserted-by":"publisher","first-page":"89","DOI":"10.13386\/j.issn1002-0306.2020080154","volume":"42","author":"SN Huang","year":"2021","unstructured":"Huang, S. N., Gao, M. X., & Liu, Y. B. (2021). Regulatory effect of 5 metal ions on the spectrum of major secondary metabolites of Monascus purpureus. Science and Technology of Food Industry, 42(10), 89\u201399. https:\/\/doi.org\/10.13386\/j.issn1002-0306.2020080154","journal-title":"Science and Technology of Food Industry"},{"key":"5638_CR28","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.ijbiomac.2020.07.131","volume":"164","author":"G Zhang","year":"2020","unstructured":"Zhang, G., Wang, G., Zhu, C., Wang, C., Wang, D., & Wei, G. (2020). Metabolic flux and transcriptome analyses provide insights into the mechanism underlying zinc sulfate improved \u03b2-1,3-D-glucan production by Aureobasidium pullulans. International Journal of Biological Macromolecules, 164, 140\u2013148. https:\/\/doi.org\/10.1016\/j.ijbiomac.2020.07.131","journal-title":"International Journal of Biological Macromolecules"},{"issue":"4","key":"5638_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2013-14-4-r36","volume":"14","author":"D Kim","year":"2013","unstructured":"Kim, D., Pertea, G., Trapnell, C., Pimentel, H., Kelley, R., & Salzberg, S. L. (2013). TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biology, 14(4), Article R36. https:\/\/doi.org\/10.1186\/gb-2013-14-4-r36","journal-title":"Genome Biology"},{"issue":"5","key":"5638_CR30","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1038\/nbt.1621","volume":"28","author":"C Trapnell","year":"2010","unstructured":"Trapnell, C., Williams, B. A., Pertea, G., Mortazavi, A., Kwan, G., van Baren, M. J., Salzberg, S. L., Wold, B. J., & Pachter, L. (2010). Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nature Biotechnology, 28(5), 511\u20135. https:\/\/doi.org\/10.1038\/nbt.1621","journal-title":"Nature Biotechnology"},{"issue":"10","key":"5638_CR31","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2010-11-10-r106","volume":"11","author":"S Anders","year":"2010","unstructured":"Anders, S., & Huber, W. (2010). Differential expression analysis for sequence count data. Genome Biology, 11(10), Article R106. https:\/\/doi.org\/10.1186\/gb-2010-11-10-r106","journal-title":"Genome Biology"},{"issue":"5","key":"5638_CR32","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1080\/00275514.1970.12019044","volume":"62","author":"F McHan","year":"1970","unstructured":"McHan, F., & Johnson, G. T. (1970). Zinc and amino acids: Important components of a medium promoting growth of Monascus Purpureus. Mycologia, 62(5), 1018\u20131031. https:\/\/doi.org\/10.1080\/00275514.1970.12019044","journal-title":"Mycologia"},{"key":"5638_CR33","doi-asserted-by":"publisher","unstructured":"Xue, X., & Gao, L. (2013). Expression of Aminolevulinate Dehydratase During Mycelium Development in Monascus purpureus. Advanced Materials Research, 641\u2013642, 760\u2013764. https:\/\/doi.org\/10.4028\/www.scientific.net\/AMR.641-642","DOI":"10.4028\/www.scientific.net\/AMR.641-642"},{"issue":"2","key":"5638_CR34","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1111\/j.1365-2958.2007.05807.x","volume":"65","author":"MA Pagani","year":"2007","unstructured":"Pagani, M. A., Casamayor, A., Serrano, R., Atrian, S., & Ari\u00f1o, J. (2007). Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: A genome-wide study. Molecular Microbiology, 65(2), 521\u201337. https:\/\/doi.org\/10.1111\/j.1365-2958.2007.05807.x","journal-title":"Molecular Microbiology"},{"issue":"4","key":"5638_CR35","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.jbiotec.2004.09.011","volume":"115","author":"G Panagiotou","year":"2005","unstructured":"Panagiotou, G., Villas-B\u00f4as, S. G., Christakopoulos, P., Nielsen, J., & Olsson, L. (2005). Intracellular metabolite profiling of Fusarium oxysporum converting glucose to ethanol. Journal of Biotechnology, 115(4), 425\u201334. https:\/\/doi.org\/10.1016\/j.jbiotec.2004.09.011","journal-title":"Journal of Biotechnology"},{"key":"5638_CR36","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.ymben.2023.06.009","volume":"78","author":"Y Zhang","year":"2023","unstructured":"Zhang, Y., Sun, T., Wu, T., Li, J., Hu, D., Liu, D., Li, J., & Tian, C. (2023). Consolidated bioprocessing for bioethanol production by metabolically engineered cellulolytic fungus Myceliophthora thermophila. Metabolic Engineering, 78, 192\u2013199. https:\/\/doi.org\/10.1016\/j.ymben.2023.06.009","journal-title":"Metabolic Engineering"},{"issue":"18","key":"5638_CR37","doi-asserted-by":"publisher","DOI":"10.3390\/cells12182239","volume":"12","author":"JF Guti\u00e9rrez-Corona","year":"2023","unstructured":"Guti\u00e9rrez-Corona, J. F., Gonz\u00e1lez-Hern\u00e1ndez, G. A., Padilla-Guerrero, I. E., Olmedo-Monfil, V., Mart\u00ednez-Rocha, A. L., Pati\u00f1o-Medina, J. A., Meza-Carmen, V., & Torres-Guzm\u00e1n, J. C. (2023). Fungal alcohol dehydrogenases: Physiological function, molecular properties, regulation of their production, and biotechnological potential. Cells, 12(18), Article 2239. https:\/\/doi.org\/10.3390\/cells12182239","journal-title":"Cells"},{"issue":"9","key":"5638_CR38","doi-asserted-by":"publisher","first-page":"2563","DOI":"10.1021\/acs.jafc.8b05524","volume":"67","author":"C Zhang","year":"2019","unstructured":"Zhang, C., Liang, J., Zhang, A., Hao, S., Zhang, H., Zhu, Q., Sun, B., & Wang, C. (2019). Overexpression of monacolin K biosynthesis genes in the Monascus purpureus azaphilone polyketide pathway. Journal of Agricultural and Food Chemistry, 67(9), 2563\u20132569. https:\/\/doi.org\/10.1021\/acs.jafc.8b05524","journal-title":"Journal of Agricultural and Food Chemistry"},{"issue":"1","key":"5638_CR39","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1111\/j.1399-3054.1979.tb03187.x","volume":"46","author":"YS Bau","year":"1979","unstructured":"Bau, Y. S., & Wong, H. C. (1979). Zinc effects on growth, pigmentation and antibacterial activity of Monascus purpureus. Physiologia Plantarum, 46(1), 63\u201367. https:\/\/doi.org\/10.1111\/j.1399-3054.1979.tb03187.x","journal-title":"Physiologia Plantarum"},{"issue":"3","key":"5638_CR40","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1023\/A:1023609427750","volume":"19","author":"RM Dom\u00ednguez-Espinosa","year":"2003","unstructured":"Dom\u00ednguez-Espinosa, R. M., & Webb, C. (2003). Submerged fermentation in wheat substrates for production of Monascus pigments. World Journal of Microbiology and Biotechnology, 19(3), 329\u2013336. https:\/\/doi.org\/10.1023\/A:1023609427750","journal-title":"World Journal of Microbiology and Biotechnology"},{"issue":"4","key":"5638_CR41","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.03210-24","volume":"13","author":"K Aoki","year":"2025","unstructured":"Aoki, K., Ohkuma, M., Sugita, T., Kobayashi, Y., Tanaka, N., & Takashima, M. (2025). Analyses of hyphal diversity in Trichosporonales yeasts based on fluorescent microscopic observations. Microbiology Spectrum, 13(4), Article e0321024. https:\/\/doi.org\/10.1128\/spectrum.03210-24","journal-title":"Microbiology Spectrum"},{"issue":"5","key":"5638_CR42","doi-asserted-by":"publisher","DOI":"10.3390\/md19050248","volume":"19","author":"M Venkatachalam","year":"2021","unstructured":"Venkatachalam, M., Shum-Ch\u00e9ong-Sing, A., Caro, Y., Dufoss\u00e9, L., & Fouillaud, M. (2021). OVAT analysis and response surface methodology based on nutrient sources for optimization of pigment production in the marine-derived fungus Talaromyces albobiverticillius 30548 submerged fermentation. Marine Drugs, 19(5), Article 248. https:\/\/doi.org\/10.3390\/md19050248","journal-title":"Marine Drugs"},{"issue":"1","key":"5638_CR43","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1007\/s12010-014-1258-7","volume":"175","author":"RB de Souza","year":"2015","unstructured":"de Souza, R. B., de Menezes, J. A., de Souza Rde, F., Dutra, E. D., & de Morais, M. A. Jr. (2015). Mineral composition of the sugarcane juice and its influence on the ethanol fermentation. Applied biochemistry and biotechnology, 175(1), 209\u2013222. https:\/\/doi.org\/10.1007\/s12010-014-1258-7","journal-title":"Applied biochemistry and biotechnology"},{"issue":"1","key":"5638_CR44","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.nbt.2015.09.001","volume":"33","author":"RN Comelli","year":"2016","unstructured":"Comelli, R. N., Seluy, L. G., & Isla, M. A. (2016). Optimization of a low-cost defined medium for alcoholic fermentation\u2013a case study for potential application in bioethanol production from industrial wastewaters. New Biotechnology, 33(1), 107\u201315. https:\/\/doi.org\/10.1016\/j.nbt.2015.09.001","journal-title":"New Biotechnology"},{"issue":"1","key":"5638_CR45","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1093\/pcp\/pcu157","volume":"56","author":"E Remy","year":"2015","unstructured":"Remy, E., Cabrito, T. R., Batista, R. A., Teixeira, M. C., S\u00e1-Correia, I., & Duque, P. (2015). The major facilitator superfamily transporter ZIFL2 modulates cesium and potassium homeostasis in Arabidopsis. Plant and Cell Physiology, 56(1), 148\u201362. https:\/\/doi.org\/10.1093\/pcp\/pcu157","journal-title":"Plant and Cell Physiology"},{"issue":"1","key":"5638_CR46","doi-asserted-by":"publisher","DOI":"10.3390\/plants11010102","volume":"11","author":"V Meena","year":"2021","unstructured":"Meena, V., Sharma, S., Kaur, G., Singh, B., & Pandey, A. K. (2021). Diverse functions of plant zinc-induced facilitator-like transporter for their emerging roles in crop trait enhancement. Plants, 11(1), Article 102. https:\/\/doi.org\/10.3390\/plants11010102","journal-title":"Plants"},{"issue":"2","key":"5638_CR47","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s10534-020-00282-w","volume":"34","author":"S Hans","year":"2021","unstructured":"Hans, S., Fatima, Z., & Hameed, S. (2021). Insights into the modulatory effect of magnesium on efflux mechanisms of Candida albicans reveal inhibition of ATP binding cassette multidrug transporters and dysfunctional mitochondria. BioMetals, 34(2), 329\u2013339. https:\/\/doi.org\/10.1007\/s10534-020-00282-w","journal-title":"BioMetals"},{"issue":"38","key":"5638_CR48","doi-asserted-by":"publisher","first-page":"15371","DOI":"10.1073\/pnas.1300853110","volume":"110","author":"ME Corkins","year":"2013","unstructured":"Corkins, M. E., May, M., Ehrensberger, K. M., Hu, Y. M., Liu, Y. H., Bloor, S. D., Jenkins, B., Runge, K. W., & Bird, A. J. (2013). Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast. Proceedings of the National Academy of Sciences of the United States of America, 110(38), 15371\u20136. https:\/\/doi.org\/10.1073\/pnas.1300853110","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"4","key":"5638_CR49","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1039\/c8np00060c","volume":"36","author":"W Chen","year":"2019","unstructured":"Chen, W., Feng, Y., Moln\u00e1r, I., & Chen, F. (2019). Nature and nurture: Confluence of pathway determinism with metabolic and chemical serendipity diversifies Monascus azaphilone pigments. Natural Product Reports, 36(4), 561\u2013572. https:\/\/doi.org\/10.1039\/c8np00060c","journal-title":"Natural Product Reports"},{"issue":"7","key":"5638_CR50","doi-asserted-by":"publisher","first-page":"4917","DOI":"10.1039\/c7sc00475c","volume":"8","author":"W Chen","year":"2017","unstructured":"Chen, W., Chen, R., Liu, Q., He, Y., He, K., Ding, X., Kang, L., Guo, X., Xie, N., Zhou, Y., Lu, Y., Cox, R. J., Moln\u00e1r, I., Li, M., Shao, Y., & Chen, F. (2017). Orange, red, yellow: Biosynthesis of azaphilone pigments in Monascus fungi. Chemical Science, 8(7), 4917\u20134925. https:\/\/doi.org\/10.1039\/c7sc00475c","journal-title":"Chemical Science"},{"key":"5638_CR51","doi-asserted-by":"publisher","DOI":"10.1016\/j.fm.2024.104698","volume":"127","author":"X Zhang","year":"2025","unstructured":"Zhang, X., Chen, W., & Wang, C. (2025). Regulation of citrinin biosynthesis in Monascus purpureus: Impacts on growth, morphology, and pigments production. Food Microbiology, 127, Article 104698. https:\/\/doi.org\/10.1016\/j.fm.2024.104698","journal-title":"Food Microbiology"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05638-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12010-026-05638-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05638-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:17:54Z","timestamp":1777882674000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12010-026-05638-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,10]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["5638"],"URL":"https:\/\/doi.org\/10.1007\/s12010-026-05638-5","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,10]]},"assertion":[{"value":"3 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"All authors are aware of the content and agree with the submission.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare that they have no conflict of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}