{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T03:50:05Z","timestamp":1782100205061,"version":"3.54.5"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s12010-026-05689-8","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T02:34:22Z","timestamp":1776393262000},"page":"5293-5308","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-\u03baB Pathway"],"prefix":"10.1007","volume":"198","author":[{"given":"Yongsheng","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhonglu","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"issue":"2","key":"5689_CR1","first-page":"165","volume":"106","author":"K Haque","year":"2022","unstructured":"Haque, K., & Bhargava, P. (2022). Abdominal Aortic Aneurysm. Am Fam Physician, 106(2), 165\u2013172.","journal-title":"Am Fam Physician"},{"issue":"4","key":"5689_CR2","doi-asserted-by":"publisher","first-page":"273","DOI":"10.5455\/msm.2019.31.273-276","volume":"31","author":"N Rustempasic","year":"2019","unstructured":"Rustempasic, N., & Semi, S. (2019). Correlation of Atherosclerotic Risk Factors with the Size of Abdominal Aortic Aneurysm (AAA). Mater Sociomed, 31(4), 273\u2013276.","journal-title":"Mater Sociomed"},{"issue":"2","key":"5689_CR3","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.ejvs.2017.11.028","volume":"55","author":"P Regnier","year":"2018","unstructured":"Regnier, P., Lareyre, F., Hassen-Khodja, R., Durand, M., Touma, J., & Raffort, J. (2018). Sexual Dysfunction After Abdominal Aortic Aneurysm Surgical Repair: Current Knowledge and Future Directions. European Journal Of Vascular And Endovascular Surgery, 55(2), 267\u2013280.","journal-title":"European Journal Of Vascular And Endovascular Surgery"},{"issue":"29","key":"5689_CR4","doi-asserted-by":"publisher","first-page":"2682","DOI":"10.1093\/eurheartj\/ehad386","volume":"44","author":"J Golledge","year":"2023","unstructured":"Golledge, J., Thanigaimani, S., Powell, J. T., & Tsao, P. S. (2023). Pathogenesis and management of abdominal aortic aneurysm. European Heart Journal, 44(29), 2682\u20132697.","journal-title":"European Heart Journal"},{"issue":"24","key":"5689_CR5","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1161\/JAHA.121.023601","volume":"10","author":"H Lu","year":"2021","unstructured":"Lu, H., Du, W., Ren, L., Hamblin, M. H., Becker, R. C., Chen, Y. E., & Fan, Y. (2021). Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms. J Am Heart Assoc, 10(24), 19.","journal-title":"J Am Heart Assoc"},{"issue":"10","key":"5689_CR6","doi-asserted-by":"publisher","first-page":"e202","DOI":"10.1161\/CIRCRESAHA.121.319374","volume":"129","author":"D Cai","year":"2021","unstructured":"Cai, D., Sun, C., Zhang, G., Que, X., Fujise, K., Weintraub, N. L., & Chen, S. Y. (2021). A Novel Mechanism Underlying Inflammatory Smooth Muscle Phenotype in Abdominal Aortic Aneurysm. Circ Res, 129(10), e202\u2013e214.","journal-title":"Circ Res"},{"issue":"12","key":"5689_CR7","doi-asserted-by":"publisher","first-page":"2378","DOI":"10.1016\/j.cjca.2024.08.274","volume":"40","author":"J Zhu","year":"2024","unstructured":"Zhu, J., Meganathan, I., MacAruthur, R., & Kassiri, Z. (2024). Inflammation in Abdominal Aortic Aneurysm: Cause or Comorbidity? Canadian Journal Of Cardiology, 40(12), 2378\u20132391.","journal-title":"Canadian Journal Of Cardiology"},{"key":"5689_CR8","doi-asserted-by":"publisher","first-page":"989933","DOI":"10.3389\/fimmu.2022.989933","volume":"13","author":"AC M\u00e1rquez-S\u00e1nchez","year":"2022","unstructured":"M\u00e1rquez-S\u00e1nchez, A. C., & Koltsova, E. K. (2022). Immune and inflammatory mechanisms of abdominal aortic aneurysm. Frontiers In Immunology, 13, 989933.","journal-title":"Frontiers In Immunology"},{"issue":"176307","key":"5689_CR9","first-page":"29","volume":"965","author":"B Wei","year":"2024","unstructured":"Wei, B., Deng, N., Guo, H., Wei, Y., Xu, F., Luo, S., You, W., Chen, J., Li, W., & Si, X. (2024). Trimethylamine N-oxide promotes abdominal aortic aneurysm by inducing vascular inflammation and vascular smooth muscle cell phenotypic switching. European Journal Of Pharmacology, 965(176307), 29.","journal-title":"European Journal Of Pharmacology"},{"key":"5689_CR10","doi-asserted-by":"crossref","unstructured":"Hou, N., Zhou, H., Li, J., Xiong, X., Deng, H., & Xiong, S. (2024). Macrophage polarization and metabolic reprogramming in abdominal aortic aneurysm. Immunity Inflammation and Disease, 12(11), e1268.","DOI":"10.1002\/iid3.1268"},{"issue":"1","key":"5689_CR11","doi-asserted-by":"publisher","first-page":"024","DOI":"10.1038\/s41467-024-46983-5","volume":"15","author":"LDW Luu","year":"2024","unstructured":"Luu, L. D. W., Pandey, A., Paramsothy, S., Ngo, C., Casta\u00f1o-Rodr\u00edguez, N., Liu, C., Kamm, M. A., Borody, T. J., Man, S. M., & Kaakoush, N. O. (2024). Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice. Nature Communications, 15(1), 024\u201346983.","journal-title":"Nature Communications"},{"issue":"109892","key":"5689_CR12","first-page":"5","volume":"259","author":"HW Chiu","year":"2024","unstructured":"Chiu, H. W., Lin, C. H., Lee, H. H., Lu, H. W., Lin, Y. K., Lin, Y. F., & Lee, H. L. (2024). Guanylate binding protein 5 triggers NF-\u03baB activation to foster radioresistance, metastatic progression and PD-L1 expression in oral squamous cell carcinoma. Clin Immunol, 259(109892), 5.","journal-title":"Clin Immunol"},{"issue":"1","key":"5689_CR13","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1080\/01902148.2024.2339269","volume":"50","author":"J Li","year":"2024","unstructured":"Li, J., Liu, K., He, W., Zhang, W., & Li, Y. (2024). Inhibition of GBP5 activates autophagy to alleviate inflammatory response in LPS-induced lung injury in mice. Experimental Lung Research, 50(1), 106\u2013117.","journal-title":"Experimental Lung Research"},{"key":"5689_CR14","doi-asserted-by":"publisher","first-page":"4153","DOI":"10.2147\/JIR.S401430","volume":"16","author":"Q Tong","year":"2023","unstructured":"Tong, Q., Li, D., Yin, Y., Cheng, L., & Ouyang, S. (2023). GBP5 Expression Predicted Prognosis of Immune Checkpoint Inhibitors in Small Cell Lung Cancer and Correlated with Tumor Immune Microenvironment. J Inflamm Res, 16, 4153\u20134164.","journal-title":"J Inflamm Res"},{"key":"5689_CR15","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jot.2023.11.005","volume":"44","author":"H Tang","year":"2023","unstructured":"Tang, H., Gong, X., Dai, J., Gu, J., Dong, Z., Xu, Y., Hu, Z., Zhao, C., Deng, J., & Dong, S. (2023). The IRF1\/GBP5 axis promotes osteoarthritis progression by activating chondrocyte pyroptosis. J Orthop Translat, 44, 47\u201359.","journal-title":"J Orthop Translat"},{"issue":"9","key":"5689_CR16","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1248\/bpb.b21-00042","volume":"44","author":"R Qiu","year":"2021","unstructured":"Qiu, R., Chen, S., Hua, F., Bian, S., Chen, J., Li, G., & Wu, X. (2021). Betanin Prevents Experimental Abdominal Aortic Aneurysm Progression by Modulating the TLR4\/NF-\u03baB and Nrf2\/HO-1 Pathways. Biological &\/And Pharmaceutical Bulletin, 44(9), 1254\u20131262.","journal-title":"Biological &\/And Pharmaceutical Bulletin"},{"issue":"4","key":"5689_CR17","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1080\/15384101.2022.2124489","volume":"22","author":"M Dai","year":"2023","unstructured":"Dai, M., Zhu, X., Zeng, S., Liu, Q., Hu, R., Huang, L., Wang, Y., Deng, J., & Yu, Q. (2023). Dexmedetomidine protects cells from Angiotensin II-induced smooth muscle cell phenotype switch and endothelial cell dysfunction. Cell Cycle, 22(4), 450\u2013463.","journal-title":"Cell Cycle"},{"issue":"4","key":"5689_CR18","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1111\/jdv.18725","volume":"37","author":"L Zhou","year":"2023","unstructured":"Zhou, L., Zhao, H., Meng, X., Zhao, Z., Xie, H., Li, J., Tang, Y., & Zhang, Y. (2023). GBP5 exacerbates rosacea-like skin inflammation by skewing macrophage polarization towards M1 phenotype through the NF-\u03baB signalling pathway. Journal Of The European Academy Of Dermatology And Venereology, 37(4), 796\u2013809.","journal-title":"Journal Of The European Academy Of Dermatology And Venereology"},{"issue":"10","key":"5689_CR19","doi-asserted-by":"publisher","first-page":"4471","DOI":"10.1073\/pnas.89.10.4471","volume":"89","author":"JA Piedrahita","year":"1992","unstructured":"Piedrahita, J. A., Zhang, S. H., Hagaman, J. R., Oliver, P. M., & Maeda, N. (1992). Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci U S A, 89(10), 4471\u20134475. https:\/\/doi.org\/10.1073\/pnas.89.10.4471","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"5689_CR20","doi-asserted-by":"publisher","first-page":"2504","DOI":"10.1038\/s41401-023-01124-4","volume":"44","author":"JM Li","year":"2023","unstructured":"Li, J. M., Deng, H. S., Yao, Y. D., Wang, W. T., Hu, J. Q., Dong, Y., Wang, P. X., Liu, L., Liu, Z. Q., Xie, Y., Lu, L. L., & Zhou, H. (2023). Sinomenine ameliorates collagen-induced arthritis in mice by targeting GBP5 and regulating the P2X7 receptor to suppress NLRP3-related signaling pathways. Acta Pharmacologica Sinica, 44(12), 2504\u20132524.","journal-title":"Acta Pharmacologica Sinica"},{"issue":"2","key":"5689_CR21","doi-asserted-by":"publisher","first-page":"021","DOI":"10.1038\/s41419-021-03492-3","volume":"12","author":"X Yu","year":"2021","unstructured":"Yu, X., Jin, J., Zheng, Y., Zhu, H., Xu, H., Ma, J., Lan, Q., Zhuang, Z., Chen, C. C., & Li, M. (2021). GBP5 drives malignancy of glioblastoma via the Src\/ERK1\/2\/MMP3 pathway. Cell Death And Disease, 12(2), 021\u201303492.","journal-title":"Cell Death And Disease"},{"issue":"111734","key":"5689_CR22","first-page":"28","volume":"130","author":"J Zhang","year":"2024","unstructured":"Zhang, J., Zhang, Y., Chen, Q., Qi, Y., & Zhang, X. (2024). The XPO1 inhibitor selinexor ameliorates bleomycin-induced pulmonary fibrosis in mice via GBP5\/NLRP3 inflammasome signaling. International Immunopharmacology, 130(111734), 28.","journal-title":"International Immunopharmacology"},{"issue":"4","key":"5689_CR23","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1159\/000460294","volume":"9","author":"J Feng","year":"2017","unstructured":"Feng, J., Cao, Z., Wang, L., Wan, Y., Peng, N., Wang, Q., Chen, X., Zhou, Y., & Zhu, Y. (2017). Inducible GBP5 Mediates the Antiviral Response via Interferon-Related Pathways during Influenza A Virus Infection. Journal Of Innate Immunity, 9(4), 419\u2013435.","journal-title":"Journal Of Innate Immunity"},{"issue":"10","key":"5689_CR24","first-page":"023","volume":"7","author":"K Zhong","year":"2023","unstructured":"Zhong, K., Liu, K., Song, Y., Chen, S., Hu, X., Xue, R., Ma, X., Li, S., Yang, J., Deng, Z., Zhu, X., Yuan, M., Huang, Y., Yin, W., Chen, Y., Tang, Y., & Shi, Z. (2023). A Synthetic Steroid 5\u03b1-Androst-3\u03b2, 5, 6\u03b2-triol Alleviates Radiation-Induced Brain Injury in Mice via Inhibiting GBP5\/NF-\u03baB\/NLRP3 Signal Axis. Molecular Neurobiology, 7(10), 023\u201303831.","journal-title":"Molecular Neurobiology"},{"key":"5689_CR25","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.actbio.2019.01.070","volume":"88","author":"JA Niestrawska","year":"2019","unstructured":"Niestrawska, J. A., Regitnig, P., Viertler, C., Cohnert, T. U., Babu, A. R., & Holzapfel, G. A. (2019). The role of tissue remodeling in mechanics and pathogenesis of abdominal aortic aneurysms. Acta Biomaterialia, 88, 149\u2013161.","journal-title":"Acta Biomaterialia"},{"issue":"4","key":"5689_CR26","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1016\/j.ejvs.2008.11.027","volume":"37","author":"L Karlsson","year":"2009","unstructured":"Karlsson, L., Bergqvist, D., Lindb\u00e4ck, J., & P\u00e4rsson, H. (2009). Expansion of small-diameter abdominal aortic aneurysms is not reflected by the release of inflammatory mediators IL-6, MMP-9 and CRP in plasma. European Journal Of Vascular And Endovascular Surgery, 37(4), 420\u2013424.","journal-title":"European Journal Of Vascular And Endovascular Surgery"},{"issue":"8","key":"5689_CR27","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nrcardio.2017.52","volume":"14","author":"J Raffort","year":"2017","unstructured":"Raffort, J., Lareyre, F., Cl\u00e9ment, M., Hassen-Khodja, R., Chinetti, G., & Mallat, Z. (2017). Monocytes and macrophages in abdominal aortic aneurysm. Nature Reviews. Cardiology, 14(8), 457\u2013471.","journal-title":"Nature Reviews. Cardiology"},{"key":"5689_CR28","doi-asserted-by":"publisher","first-page":"1341464","DOI":"10.3389\/fimmu.2024.1341464","volume":"15","author":"FV Marinho","year":"2024","unstructured":"Marinho, F. V., Brito, C., de Araujo, A., & Oliveira, S. C. (2024). Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection. Frontiers In Immunology, 15, 1341464.","journal-title":"Frontiers In Immunology"},{"key":"5689_CR29","doi-asserted-by":"crossref","unstructured":"Guo, H., Ni, M., Xu, J., Chen, F., Yao, Z., Yao, Y., Liu, C., & Du, Q. (2021). Transcriptional enhancement of GBP-5 by BATF aggravates sepsis-associated liver injury via NLRP3 inflammasome activation. The FASEB Journal, 35(6), e21672.","DOI":"10.1096\/fj.202100234R"},{"issue":"1","key":"5689_CR30","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1080\/08820139.2022.2122834","volume":"52","author":"N Liu","year":"2023","unstructured":"Liu, N., Gao, Y., Liu, Y., & Liu, D. (2023). GBP5 Inhibition Ameliorates the Progression of Lupus Nephritis by Suppressing NLRP3 Inflammasome Activation. Immunol Invest, 52(1), 52\u201366.","journal-title":"Immunol Invest"},{"issue":"1","key":"5689_CR31","doi-asserted-by":"publisher","first-page":"e0146565","DOI":"10.1371\/journal.pone.0146565","volume":"11","author":"CH Lai","year":"2016","unstructured":"Lai, C. H., Wang, K. C., Lee, F. T., Tsai, H. W., Ma, C. Y., Cheng, T. L., Chang, B. I., Yang, Y. J., Shi, G. Y., & Wu, H. L. (2016). Toll-like receptor 4 is essential in the development of abdominal aortic aneurysm. PLoS One, 11(1), e0146565.","journal-title":"PLoS One"},{"issue":"2","key":"5689_CR32","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/j.atherosclerosis.2015.08.010","volume":"242","author":"C Huggins","year":"2015","unstructured":"Huggins, C., Pearce, S., Peri, F., Neumann, F., Cockerill, G., & Pirianov, G. (2015). A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development. Atherosclerosis, 242(2), 563\u2013570.","journal-title":"Atherosclerosis"},{"issue":"4","key":"5689_CR33","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1007\/s00011-023-01694-3","volume":"72","author":"S Bian","year":"2023","unstructured":"Bian, S., Yang, L., Zhao, D., Lv, L., Wang, T., & Yuan, H. (2023). HMGB1\/TLR4 signaling pathway enhances abdominal aortic aneurysm progression in mice by upregulating necroptosis. Inflammation Research, 72(4), 703\u2013713.","journal-title":"Inflammation Research"},{"issue":"107841","key":"5689_CR34","first-page":"18","volume":"98","author":"B Ren","year":"2021","unstructured":"Ren, B., Feng, J., Yang, N., Guo, Y., Chen, C., & Qin, Q. (2021). Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1\/NF-\u03baB pathway. International Immunopharmacology, 98(107841), 18.","journal-title":"International Immunopharmacology"},{"issue":"12","key":"5689_CR35","doi-asserted-by":"publisher","first-page":"2650","DOI":"10.1161\/HYPERTENSIONAHA.123.21348","volume":"80","author":"J Zhang","year":"2023","unstructured":"Zhang, J., Yin, Z., Xu, Y., Wei, C., Peng, S., Zhao, M., Liu, J., Xu, S., Pan, W., Zheng, Z., Liu, S., Ye, J., Qin, J. J., Wan, J., & Wang, M. (2023). Resolvin E1\/ChemR23 Protects Against Hypertension and Vascular Remodeling in Angiotensin II-Induced Hypertensive Mice. Hypertension, 80(12), 2650\u20132664.","journal-title":"Hypertension"},{"issue":"3","key":"5689_CR36","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1093\/cvr\/cvt230","volume":"100","author":"SH Tsai","year":"2013","unstructured":"Tsai, S. H., Huang, P. H., Peng, Y. J., Chang, W. C., Tsai, H. Y., Leu, H. B., Chen, J. W., & Lin, S. J. (2013). Zoledronate attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of Rho\/ROCK-dependent JNK and NF-\u03baB pathway. Cardiovasc Res, 100(3), 501\u2013510.","journal-title":"Cardiovasc Res"},{"key":"5689_CR37","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/bs.ircmb.2017.07.007","volume":"335","author":"JP Mitchell","year":"2018","unstructured":"Mitchell, J. P., & Carmody, R. J. (2018). NF-\u03baB and the Transcriptional Control of Inflammation. International review of cell and molecular biology, 335, 41\u201384. https:\/\/doi.org\/10.1016\/bs.ircmb.2017.07.007","journal-title":"International review of cell and molecular biology"},{"key":"5689_CR38","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.avsg.2021.06.003","volume":"77","author":"S Chen","year":"2021","unstructured":"Chen, S., Luo, K., Bian, S., Chen, J., Qiu, R., Wu, X., & Li, G. (2021). Paeonol Ameliorates Abdominal Aortic Aneurysm Progression by the NF-\u03baB Pathway. Annals Of Vascular Surgery, 77, 255\u2013262.","journal-title":"Annals Of Vascular Surgery"},{"issue":"2","key":"5689_CR39","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1002\/ptr.7358","volume":"36","author":"Z Zhai","year":"2022","unstructured":"Zhai, Z., Zhang, X., Ding, Y., Huang, Z., Li, Q., Zheng, M., Cho, K., Dong, Z., Fu, W., Chen, Z., & Jiang, B. (2022). Eugenol restrains abdominal aortic aneurysm progression with down-regulations on NF-\u03baB and COX-2. Phytotherapy Research: Ptr, 36(2), 928\u2013937. https:\/\/doi.org\/10.1002\/ptr.7358","journal-title":"Phytotherapy Research: Ptr"},{"issue":"4","key":"5689_CR40","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1111\/jdv.18725","volume":"37","author":"L Zhou","year":"2023","unstructured":"Zhou, L., Zhao, H., Zhao, H., Meng, X., Zhao, Z., Xie, H., Li, J., Tang, Y., & Zhang, Y. (2023). GBP5 exacerbates rosacea-like skin inflammation by skewing macrophage polarization towards M1 phenotype through the NF-\u03baB signalling pathway. Journal Of The European Academy Of Dermatology And Venereology, 37(4), 796\u2013809. https:\/\/doi.org\/10.1111\/jdv.18725","journal-title":"Journal Of The European Academy Of Dermatology And Venereology"},{"issue":"6","key":"5689_CR41","doi-asserted-by":"publisher","first-page":"117","DOI":"10.15586\/aei.v52i6.1188","volume":"52","author":"F Ren","year":"2024","unstructured":"Ren, F., Li, J., Ni, X., Yuan, H., & Yan, W. (2024). Knockdown of GBP5 alleviates renal damage caused by psoriasis by regulating NF-\u03baB\/STAT3 pathway. Allergologia et immunopathologia, 52(6), 117\u2013127. https:\/\/doi.org\/10.15586\/aei.v52i6.1188","journal-title":"Allergologia et immunopathologia"},{"key":"5689_CR42","doi-asserted-by":"crossref","unstructured":"Qian, G., Adeyanju, O., Olajuyin, A., & Guo, X. (2022). Abdominal aortic aneurysm formation with a focus on vascular smooth muscle cells. Life, 12(2).","DOI":"10.3390\/life12020191"},{"key":"5689_CR43","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.atherosclerosis.2019.08.016","volume":"289","author":"Y Wang","year":"2019","unstructured":"Wang, Y., Jia, L., Xie, Y., Cai, Z., Liu, Z., Shen, J., Lu, Y., Su, S., Ma, Y., & Xiang, M. (2019). Involvement of macrophage-derived exosomes in abdominal aortic aneurysms development. Atherosclerosis, 289, 64\u201372.","journal-title":"Atherosclerosis"},{"issue":"1","key":"5689_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10735-021-10035-9","volume":"53","author":"Z Zhou","year":"2022","unstructured":"Zhou, Z., Zhou, H., Zou, X., & Wang, X. (2022). RUNX3 is up-regulated in abdominal aortic aneurysm and regulates the function of vascular smooth muscle cells by regulating TGF-\u03b21. Journal Of Molecular Histology, 53(1), 1\u201311.","journal-title":"Journal Of Molecular Histology"},{"issue":"116170","key":"5689_CR45","first-page":"26","volume":"223","author":"K Zhang","year":"2024","unstructured":"Zhang, K., Li, R., Matniyaz, Y., Yu, R., Pan, J., Liu, W., & Wang, D. (2024). Liraglutide attenuates angiotensin II-induced aortic dissection and aortic aneurysm via inhibiting M1 macrophage polarization in APOE (-\/-) mice. Biochemical Pharmacology, 223(116170), 26.","journal-title":"Biochemical Pharmacology"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05689-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12010-026-05689-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05689-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T03:28:23Z","timestamp":1782098903000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12010-026-05689-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,17]]},"references-count":45,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["5689"],"URL":"https:\/\/doi.org\/10.1007\/s12010-026-05689-8","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,17]]},"assertion":[{"value":"31 March 2026","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2026","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The experimental protocol of our study was performed in accordance with the Guide for the Care and Use of Laboratory Animals and approved by Shandong Provincial Third Hospital, Shandong University (DWKYLL-2024329).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare that they have no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}