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All subjects were approved by The First Affiliated Hospital of Xinxiang Medical University (Approval No.EC-022-138). All animal experiments were complied with the ARRIVE guidelines and performed in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals. The experiments were approved by the Institutional Animal Care and Use Committee of the First Affiliated Hospital of Xinxiang Medical University (Approval No.EC-024-369).","order":4,"name":"Ethics","label":"Ethics Statement","group":{"name":"EthicsHeading","label":"Declarations"}}]}}