{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T04:06:41Z","timestamp":1788926801939,"version":"build-2803163510"},"reference-count":135,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"DOI":"10.1007\/s12010-026-05894-5","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:35:10Z","timestamp":1788924910000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effective Abatement of Multidrug-resistant Pathogens Employing Natural Polyphenols and Polyphenol-based Formulations: A Systematic Review and Integrated Network Pharmacology Approach"],"prefix":"10.1007","author":[{"given":"Qi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2092-0694","authenticated-orcid":false,"given":"Annadurai","family":"Vinothkanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4747-1374","authenticated-orcid":false,"given":"Ragothaman","family":"Prathiviraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Durairaj","family":"Karthick Rajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuntong","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junyan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenbo","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"key":"5894_CR1","unstructured":"World Health Organization (WHO) (2025). Regional Roadmap to accelerate actions on antimicrobial resistance in the human health sector in the South-East Asia Region (2025\u20132030). WHO, South-East Asia Region, (1), 01\u201345. Retrieved from https:\/\/iris.who.int\/server\/api\/core\/bitstreams\/eb974779-82b5-445e-8b0b-255e4e66379c\/content"},{"key":"5894_CR2","doi-asserted-by":"publisher","unstructured":"Coque T, Graham DW, Pruden A, So A, Topp E (2023). Bracing for Superbugs: Strengthening environmental action in the One Health response to antimicrobial resistance. United Nations Environment Programme, Geneva. https:\/\/doi.org\/10.57711\/hdq2-xr65","DOI":"10.57711\/hdq2-xr65"},{"issue":"1","key":"5894_CR3","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s12992-024-01046-8","volume":"20","author":"B Aslam","year":"2024","unstructured":"Aslam, B., Asghar, R., Muzammil, S., Shafique, M., Siddique, A. B., Khurshid, M., & Baloch, Z. (2024). AMR and Sustainable Development Goals: At a crossroads. Globalization and Health,20(1), 73. https:\/\/doi.org\/10.1186\/s12992-024-01046-8","journal-title":"Globalization and Health"},{"key":"5894_CR4","doi-asserted-by":"publisher","first-page":"1415400","DOI":"10.3389\/fmicb.2024.1415400","volume":"15","author":"D Mazzantini","year":"2024","unstructured":"Mazzantini, D., Massimino, M., Calvigioni, M., Rossi, V., Celandroni, F., Lupetti, A., & Ghelardi, E. (2024). Anti-staphylococcal activity of a polyphenol-rich citrus extract: Synergy with \u03b2-lactams and low proficiency to induce resistance. Frontiers in Microbiology,15, 1415400. https:\/\/doi.org\/10.3389\/fmicb.2024.1415400","journal-title":"Frontiers in Microbiology"},{"key":"5894_CR5","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2023-0175","author":"MEM Elkhalifa","year":"2024","unstructured":"Elkhalifa, M. E. M., Ashraf, M., Ahmed, A., Usman, A., Hamdoon, A. A. E., Elawad, M. A., Elkhalifa, M. E. M., Hamdoon, A. A. E., Almalki, M. G., Mosa, O. F., Niyazov, L. N., & Ayaz, M. (2024). Polyphenols and their nanoformulations as potential antibiofilm agents against multidrug-resistant pathogens. Future Microbiology. https:\/\/doi.org\/10.2217\/fmb-2023-0175","journal-title":"Future Microbiology"},{"key":"5894_CR6","doi-asserted-by":"publisher","unstructured":"Galanakis, C. M. (2018). Polyphenols: Properties, recovery, and applications. Polyphenols: Properties, Recovery, and Applications. https:\/\/doi.org\/10.1016\/C2016-0-05057-X","DOI":"10.1016\/C2016-0-05057-X"},{"key":"5894_CR7","doi-asserted-by":"publisher","DOI":"10.1080\/10942912.2017.1354017","author":"H Rasouli","year":"2017","unstructured":"Rasouli, H., Farzaei, M. H., & Khodarahmi, R. (2017). Polyphenols and their benefits: A review. International Journal of Food Properties. https:\/\/doi.org\/10.1080\/10942912.2017.1354017","journal-title":"International Journal of Food Properties"},{"key":"5894_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/nu8080515","author":"Y Zhou","year":"2016","unstructured":"Zhou, Y., Zheng, J., Li, Y., Xu, D. P., Li, S., Chen, Y. M., & Li, H. B. (2016). Natural polyphenols for prevention and treatment of cancer. Nutrients. https:\/\/doi.org\/10.3390\/nu8080515","journal-title":"Nutrients"},{"key":"5894_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6419","author":"A Durazzo","year":"2019","unstructured":"Durazzo, A., Lucarini, M., Souto, E. B., Cicala, C., Caiazzo, E., Izzo, A. A., Novellino, E., & Santini, A. (2019). Polyphenols: A concise overview on the chemistry, occurrence, and human health. Phytotherapy Research. https:\/\/doi.org\/10.1002\/ptr.6419","journal-title":"Phytotherapy Research"},{"key":"5894_CR10","doi-asserted-by":"publisher","DOI":"10.5740\/jaoacint.19-0133","author":"RK Singla","year":"2019","unstructured":"Singla, R. K., Dubey, A. K., Garg, A., Sharma, R. K., Fiorino, M., Ameen, S. M., Haddad, M. A., & Al-Hiary, M. (2019). Natural polyphenols: Chemical classification, definition of classes, subcategories, and structures. Journal of AOAC International. https:\/\/doi.org\/10.5740\/jaoacint.19-0133","journal-title":"Journal of AOAC International"},{"key":"5894_CR11","doi-asserted-by":"publisher","DOI":"10.3390\/nu6126020","author":"AN Li","year":"2014","unstructured":"Li, A. N., Li, S., Zhang, Y. J., Xu, X. R., Chen, Y. M., & Li, H. B. (2014). Resources and biological activities of natural polyphenols. Nutrients. https:\/\/doi.org\/10.3390\/nu6126020","journal-title":"Nutrients"},{"key":"5894_CR12","doi-asserted-by":"publisher","DOI":"10.3390\/foods10112595","author":"A Bertelli","year":"2021","unstructured":"Bertelli, A., Biagi, M., Corsini, M., Baini, G., Cappellucci, G., & Miraldi, E. (2021). Polyphenols: From theory to practice. Foods. https:\/\/doi.org\/10.3390\/foods10112595","journal-title":"Foods"},{"key":"5894_CR13","doi-asserted-by":"publisher","DOI":"10.1111\/nbu.12278","author":"G Williamson","year":"2017","unstructured":"Williamson, G. (2017). The role of polyphenols in modern nutrition. Nutrition Bulletin. https:\/\/doi.org\/10.1111\/nbu.12278","journal-title":"Nutrition Bulletin"},{"issue":"17","key":"5894_CR14","doi-asserted-by":"publisher","first-page":"1943","DOI":"10.2174\/1568026616666160204122449","volume":"16","author":"C Spagnuolo","year":"2016","unstructured":"Spagnuolo, C., Napolitano, M., Tedesco, I., Moccia, S., Milito, A., & Luigi Russo, G. (2016). Neuroprotective Role of Natural Polyphenols. Current Topics in Medicinal Chemistry,16(17), 1943\u201350. https:\/\/doi.org\/10.2174\/1568026616666160204122449","journal-title":"Current Topics in Medicinal Chemistry"},{"issue":"11","key":"5894_CR15","doi-asserted-by":"publisher","first-page":"7045","DOI":"10.1021\/acs.nanolett.8b03015","volume":"18","author":"C Wang","year":"2018","unstructured":"Wang, C., Sang, H., Wang, Y., Zhu, F., Hu, X., Wang, X., & Cheng, Y. (2018). Foe to Friend: Supramolecular Nanomedicines Consisting of Natural Polyphenols and Bortezomib. Nano Letters,18(11), 7045\u201351. https:\/\/doi.org\/10.1021\/acs.nanolett.8b03015","journal-title":"Nano Letters"},{"key":"5894_CR16","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.abb.2014.04.013","volume":"559","author":"PCH Hollman","year":"2014","unstructured":"Hollman, P. C. H. (2014). Unravelling of the health effects of polyphenols is a complex puzzle complicated by metabolism. Archives of Biochemistry and Biophysics,559, 100\u20135. https:\/\/doi.org\/10.1016\/j.abb.2014.04.013","journal-title":"Archives of Biochemistry and Biophysics"},{"issue":"1","key":"5894_CR17","doi-asserted-by":"publisher","first-page":"4163","DOI":"10.1038\/s41598-018-22388-5","volume":"8","author":"M Rahnasto-Rilla","year":"2018","unstructured":"Rahnasto-Rilla, M., Tyni, J., Huovinen, M., Jarho, E., Kulikowicz, T., Ravichandran, S., & Moaddel, R. (2018). Natural polyphenols as sirtuin 6 modulators. Scientific Reports,8(1), 4163. https:\/\/doi.org\/10.1038\/s41598-018-22388-5","journal-title":"Scientific Reports"},{"key":"5894_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2025.02.026","author":"J Tao","year":"2025","unstructured":"Tao, J., Sun, Y., Wang, G., Sun, J., Dong, S., & Ding, J. (2025). Advanced biomaterials for targeting mature biofilms in periodontitis therapy. Bioactive Materials. https:\/\/doi.org\/10.1016\/j.bioactmat.2025.02.026","journal-title":"Bioactive Materials"},{"key":"5894_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1548117","author":"M Kashi","year":"2025","unstructured":"Kashi, M., Varseh, M., Hariri, Y., Chegini, Z., & Shariati, A. (2025). Natural compounds: New therapeutic approach for inhibition of Streptococcus mutans and dental caries. Frontiers in Pharmacology. https:\/\/doi.org\/10.3389\/fphar.2025.1548117","journal-title":"Frontiers in Pharmacology"},{"key":"5894_CR20","doi-asserted-by":"publisher","unstructured":"Rudrapal, M., Sarkar, B., Deb, P. K., Bendale, A. R., & Nagar, A. (2024). Addressing antimicrobial resistance by repurposing polyphenolic phytochemicals with novel antibacterial potential. Polyphenols: Food, Nutraceutical, and Nanotherapeutic Applications. https:\/\/doi.org\/10.1002\/9781394188864.ch13","DOI":"10.1002\/9781394188864.ch13"},{"key":"5894_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)02081-6","author":"N Macesic","year":"2025","unstructured":"Macesic, N., Uhlemann, A. C., & Peleg, A. Y. (2025). Multidrug-resistant Gram-negative bacterial infections. Lancet. https:\/\/doi.org\/10.1016\/S0140-6736(24)02081-6","journal-title":"Lancet"},{"key":"5894_CR22","doi-asserted-by":"publisher","first-page":"100006","DOI":"10.1016\/j.bioflm.2019.100006","volume":"1","author":"KN Kragh","year":"2019","unstructured":"Kragh, K. N., Alhede, M., Kvich, L., & Bjarnsholt, T. (2019). Into the well\u2014A close look at the complex structures of a microtiter biofilm and the crystal violet assay. Biofilm,1, 100006. https:\/\/doi.org\/10.1016\/j.bioflm.2019.100006","journal-title":"Biofilm"},{"key":"5894_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioflm.2022.100080","author":"M Kolpen","year":"2022","unstructured":"Kolpen, M., Jensen, P. \u00d8., Faurholt-Jepsen, D., & Bjarnsholt, T. (2022). Prevalence of biofilms in acute infections challenges a longstanding paradigm. Biofilm. https:\/\/doi.org\/10.1016\/j.bioflm.2022.100080","journal-title":"Biofilm"},{"key":"5894_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioflm.2019.100010","author":"J Allkja","year":"2020","unstructured":"Allkja, J., Bjarnsholt, T., Coenye, T., Cos, P., Fallarero, A., Harrison, J. J., Lopes, S. P., Oliver, A., Pereira, M. O., Ramage, G., Shirtliff, M. E., Stoodley, P., Webb, J. S., Zaat, S. A. J., Goeres, D. M., & Azevedo, N. F. (2020). Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates. Biofilm. https:\/\/doi.org\/10.1016\/j.bioflm.2019.100010","journal-title":"Biofilm"},{"key":"5894_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioflm.2022.100075","author":"V Gu\u00e9neau","year":"2022","unstructured":"Gu\u00e9neau, V., Plateau-Gonthier, J., Arnaud, L., Piard, J. C., Castex, M., & Briandet, R. (2022). Positive biofilms to guide surface microbial ecology in livestock buildings. Biofilm. https:\/\/doi.org\/10.1016\/j.bioflm.2022.100075","journal-title":"Biofilm"},{"key":"5894_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioflm.2019.100017","author":"ES Gloag","year":"2020","unstructured":"Gloag, E. S., Fabbri, S., Wozniak, D. J., & Stoodley, P. (2020). Biofilm mechanics: Implications in infection and survival. Biofilm. https:\/\/doi.org\/10.1016\/j.bioflm.2019.100017","journal-title":"Biofilm"},{"key":"5894_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioflm.2025.100320","author":"S Chen","year":"2025","unstructured":"Chen, S., Dong, W., Li, S., Zhong, T., Qian, X., Cai, Y., Ye, Y., Liu, J., Xu, Z., & Yuan, W. (2025). Formation of CO2-dependent small-colony variants (SCVs) in methicillin-resistant Staphylococcus aureus mediated by a single point mutation in mpsB. Biofilm. https:\/\/doi.org\/10.1016\/j.bioflm.2025.100320","journal-title":"Biofilm"},{"key":"5894_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2023.04.009","author":"J Liu","year":"2023","unstructured":"Liu, J., Yang, L., Kjellerup, B. V., & Xu, Z. (2023). Viable but nonculturable (VBNC) state, an underestimated and controversial microbial survival strategy. Trends in Microbiology. https:\/\/doi.org\/10.1016\/j.tim.2023.04.009","journal-title":"Trends in Microbiology"},{"key":"5894_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cofs.2019.03.006","author":"Z Xu","year":"2019","unstructured":"Xu, Z., Xie, J., Soteyome, T., Peters, B. M., Shirtliff, M. E., Liu, J., & Harro, J. M. (2019). Polymicrobial interaction and biofilms between Staphylococcus aureus and Pseudomonas aeruginosa: An underestimated concern in food safety. Current Opinion in Food Science. https:\/\/doi.org\/10.1016\/j.cofs.2019.03.006","journal-title":"Current Opinion in Food Science"},{"key":"5894_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioflm.2025.100324","author":"Y Li","year":"2025","unstructured":"Li, Y., Zhou, X., Xue, H., Hong, J., Gu, N., Li, Q., Yu, G., Yin, X., Yuan, L., Premarathna, M., Lin, X., Mao, Y., Liu, J., & Xu, Z. (2025). A comprehensive study on the dual species biofilm formation of clinical Staphylococcus aureus and Candida albicans strains from the same origins. Biofilm. https:\/\/doi.org\/10.1016\/j.bioflm.2025.100324","journal-title":"Biofilm"},{"key":"5894_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2025.116386","author":"Z Xu","year":"2025","unstructured":"Xu, Z., Li, Y., Xue, L., Xu, A., Yu, G., Soteyome, T., Yuan, L., Li, X., & Liu, J. (2025). Genomic-transcriptomic analysis of Staphylococcus aureus biofilm formation under sub-MIC antibiotic exposure. Food Research International. https:\/\/doi.org\/10.1016\/j.foodres.2025.116386","journal-title":"Food Research International"},{"key":"5894_CR32","doi-asserted-by":"publisher","first-page":"100156","DOI":"10.1016\/j.bioflm.2023.100156","volume":"6","author":"J Liu","year":"2023","unstructured":"Liu, J., Huang, T., Xu, Z., Mao, Y., Soteyome, T., Liu, G., & Seneviratne, G. (2023). Sub-MIC streptomycin and tetracycline enhanced Staphylococcus aureus Guangzhou-SAU749 biofilm formation, an in-depth study on transcriptomics. Biofilm,6, 100156. https:\/\/doi.org\/10.1016\/j.bioflm.2023.100156","journal-title":"Biofilm"},{"issue":"1","key":"5894_CR33","doi-asserted-by":"publisher","first-page":"2477","DOI":"10.1038\/s41467-022-29877-2","volume":"13","author":"M Maree","year":"2022","unstructured":"Maree, M., Thi Nguyen, L. T., Ohniwa, R. L., Higashide, M., Msadek, T., & Morikawa, K. (2022). Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms. Nature Communications,13(1), 2477. https:\/\/doi.org\/10.1038\/s41467-022-29877-2","journal-title":"Nature Communications"},{"issue":"6","key":"5894_CR34","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1089\/mdr.2018.0319","volume":"25","author":"R Vivas","year":"2019","unstructured":"Vivas, R., Barbosa, A. A. T., Dolabela, S. S., & Jain, S. (2019). Multidrug-Resistant Bacteria and Alternative Methods to Control Them: An Overview. Microbial Drug Resistance,25(6), 890\u2013908. https:\/\/doi.org\/10.1089\/mdr.2018.0319","journal-title":"Microbial Drug Resistance"},{"key":"5894_CR35","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27030616","author":"A Catalano","year":"2022","unstructured":"Catalano, A., Iacopetta, D., Ceramella, J., Scumaci, D., Giuzio, F., Saturnino, C., Aquaro, S., Rosano, C., & Sinicropi, M. S. (2022). Multidrug resistance (MDR): A widespread phenomenon in pharmacological therapies. Molecules. https:\/\/doi.org\/10.3390\/molecules27030616","journal-title":"Molecules"},{"key":"5894_CR36","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9040196","author":"S Morris","year":"2020","unstructured":"Morris, S., & Cerceo, E. (2020). Trends, epidemiology, and management of multi-drug resistant gram-negative bacterial infections in the hospitalized setting. Antibiotics. https:\/\/doi.org\/10.3390\/antibiotics9040196","journal-title":"Antibiotics"},{"key":"5894_CR37","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2014.914172","author":"I Karaiskos","year":"2014","unstructured":"Karaiskos, I., & Giamarellou, H. (2014). Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: Current and emerging therapeutic approaches. Expert Opinion on Pharmacotherapy. https:\/\/doi.org\/10.1517\/14656566.2014.914172","journal-title":"Expert Opinion on Pharmacotherapy"},{"key":"5894_CR38","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000596","author":"C Cill\u00f3niz","year":"2019","unstructured":"Cill\u00f3niz, C., Domined\u00f2, C., & Torres, A. (2019). An overview of guidelines for the management of hospital-acquired and ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria. Current Opinion in Infectious Diseases. https:\/\/doi.org\/10.1097\/QCO.0000000000000596","journal-title":"Current Opinion in Infectious Diseases"},{"key":"5894_CR39","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.129080.1","author":"D Hammoudi Halat","year":"2023","unstructured":"Hammoudi Halat, D., & Ayoub Moubareck, C. (2023). Bacterial pneumonia associated with multidrug-resistant Gram-negative pathogens: Understanding epidemiology, resistance patterns, and implications with COVID-19. F1000Research. https:\/\/doi.org\/10.12688\/f1000research.129080.1","journal-title":"F1000Research"},{"key":"5894_CR40","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2019.00074","author":"M Bassetti","year":"2019","unstructured":"Bassetti, M., Peghin, M., Vena, A., & Giacobbe, D. R. (2019). Treatment of infections due to MDR Gram-negative bacteria. Frontiers in Medicine. https:\/\/doi.org\/10.3389\/fmed.2019.00074","journal-title":"Frontiers in Medicine"},{"key":"5894_CR41","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-022-03061-7","author":"A Parmanik","year":"2022","unstructured":"Parmanik, A., Das, S., Kar, B., Bose, A., Dwivedi, G. R., & Pandey, M. M. (2022). Current treatment strategies against multidrug-resistant bacteria: A review. Current Microbiology. https:\/\/doi.org\/10.1007\/s00284-022-03061-7","journal-title":"Current Microbiology"},{"key":"5894_CR42","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2017.14553","author":"B Anne-Sophie","year":"2017","unstructured":"Anne-Sophie, B., & Benoit, G. (2017). Multidrug resistant (or antimicrobial-resistant) pathogens - Alternatives to new antibiotics? Swiss Medical Weekly. https:\/\/doi.org\/10.4414\/smw.2017.14553","journal-title":"Swiss Medical Weekly"},{"key":"5894_CR43","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4682-7","author":"MH Kollef","year":"2017","unstructured":"Kollef, M. H., Bassetti, M., Francois, B., Burnham, J., Dimopoulos, G., Garnacho-Montero, J., Lipman, J., Luyt, C.-E., Nicolau, D. P., Postma, M. J., Torres, A., Welte, T., & Wunderink, R. G. (2017). The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship. Intensive Care Medicine. https:\/\/doi.org\/10.1007\/s00134-017-4682-7","journal-title":"Intensive Care Medicine"},{"key":"5894_CR44","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2019.00151","author":"I Karaiskos","year":"2019","unstructured":"Karaiskos, I., Lagou, S., Pontikis, K., Rapti, V., & Poulakou, G. (2019). The \u201cold\u201d and the \u201cnew\u201d antibiotics for MDR Gram-negative pathogens: For whom, when, and how. Frontiers in Public Health. https:\/\/doi.org\/10.3389\/fpubh.2019.00151","journal-title":"Frontiers in Public Health"},{"key":"5894_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.giant.2020.100022","author":"H Wang","year":"2020","unstructured":"Wang, H., Wang, C., Zou, Y., Hu, J., Li, Y., & Cheng, Y. (2020). Natural polyphenols in drug delivery systems: Current status and future challenges. Giant. https:\/\/doi.org\/10.1016\/j.giant.2020.100022","journal-title":"Giant"},{"key":"5894_CR46","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","author":"MJ Page","year":"2021","unstructured":"Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hr\u00f3bjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., \u2026 Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ. https:\/\/doi.org\/10.1136\/bmj.n71","journal-title":"BMJ"},{"key":"5894_CR47","doi-asserted-by":"publisher","DOI":"10.3390\/ph6121451","author":"F Nazzaro","year":"2013","unstructured":"Nazzaro, F., Fratianni, F., De Martino, L., Coppola, R., & De Feo, V. (2013). Effect of essential oils on pathogenic bacteria. Pharmaceuticals. https:\/\/doi.org\/10.3390\/ph6121451","journal-title":"Pharmaceuticals"},{"key":"5894_CR48","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2016.05.109","author":"Q Hu","year":"2016","unstructured":"Hu, Q., & Luo, Y. (2016). Polyphenol-chitosan conjugates: Synthesis, characterization, and applications. Carbohydrate Polymers. https:\/\/doi.org\/10.1016\/j.carbpol.2016.05.109","journal-title":"Carbohydrate Polymers"},{"key":"5894_CR49","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9105261","author":"WC Reygaert","year":"2018","unstructured":"Reygaert, W. C. (2018). Green tea catechins: Their use in treating and preventing infectious diseases. BioMed Research International. https:\/\/doi.org\/10.1155\/2018\/9105261","journal-title":"BioMed Research International"},{"key":"5894_CR50","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21070877","author":"A Borges","year":"2016","unstructured":"Borges, A., Abreu, A. C., Dias, C., Saavedra, M. J., Borges, F., & Sim\u00f5es, M. (2016). New perspectives on the use of phytochemicals as an emergent strategy to control bacterial infections including biofilms. Molecules. https:\/\/doi.org\/10.3390\/molecules21070877","journal-title":"Molecules"},{"key":"5894_CR51","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20225790","author":"YW Chang","year":"2019","unstructured":"Chang, Y. W., Huang, W. C., Lin, C. Y., Wang, W. H., Hung, L. C., & Chen, Y. H. (2019). Tellimagrandin II, a type of plant polyphenol extracted from Trapa bispinosa inhibits antibiotic resistance of drug-resistant Staphylococcus aureus. International Journal of Molecular Sciences. https:\/\/doi.org\/10.3390\/ijms20225790","journal-title":"International Journal of Molecular Sciences"},{"key":"5894_CR52","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00239-15","author":"VB Maisuria","year":"2015","unstructured":"Maisuria, V. B., Hosseinidoust, Z., & Tufenkji, N. (2015). Polyphenolic extract from maple syrup potentiates antibiotic susceptibility and reduces biofilm formation of pathogenic bacteria. Applied and Environmental Microbiology. https:\/\/doi.org\/10.1128\/AEM.00239-15","journal-title":"Applied and Environmental Microbiology"},{"key":"5894_CR53","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2024.102456","author":"T Du","year":"2024","unstructured":"Du, T., Liu, L., Wang, S., Feng, J., Luo, L., Zhang, L., Lan, X., Shen, Y., Shi, S., Wang, J., & Zhang, W. (2024). Molecular-level regulating intersystem crossing of polyphenols: Engineering high-efficiency phytochemical photosensitizer for MRSA elimination. Nano Today. https:\/\/doi.org\/10.1016\/j.nantod.2024.102456","journal-title":"Nano Today"},{"key":"5894_CR54","doi-asserted-by":"publisher","DOI":"10.1039\/c9na00441f","author":"S Alfei","year":"2019","unstructured":"Alfei, S., Signorello, M. G., Schito, A., Catena, S., & Turrini, F. (2019). Reshaped as polyester-based nanoparticles, gallic acid inhibits platelet aggregation, reactive oxygen species production and multi-resistant Gram-positive bacteria with an efficiency never obtained. Nanoscale Advances. https:\/\/doi.org\/10.1039\/c9na00441f","journal-title":"Nanoscale Advances"},{"key":"5894_CR55","doi-asserted-by":"publisher","first-page":"124214","DOI":"10.1016\/j.jssc.2023.124214","volume":"326","author":"P Rananaware","year":"2023","unstructured":"Rananaware, P., Brahmkhatria, V. P., Dasgupta, D., & Patel, A. (2023). Functionalized mesoporous silica for drug delivery of poorly soluble polyphenols: Synthesis, characterization, and antimicrobial action. Journal of Solid State Chemistry,326, 124214. https:\/\/doi.org\/10.1016\/j.jssc.2023.124214","journal-title":"Journal of Solid State Chemistry"},{"key":"5894_CR56","doi-asserted-by":"publisher","DOI":"10.1155\/bmri\/5595575","author":"SRA Urme","year":"2024","unstructured":"Urme, S. R. A., Ahmed, S. F., Imran, M. A. S., Akhand, M. R. N., & Khan, M. M. H. (2024). Antimicrobial activity of tea and agarwood leaf extracts against multidrug-resistant microbes. BioMed Research International. https:\/\/doi.org\/10.1155\/bmri\/5595575","journal-title":"BioMed Research International"},{"issue":"1","key":"5894_CR57","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1186\/s12866-024-03538-4","volume":"24","author":"DS ElFeky","year":"2024","unstructured":"ElFeky, D. S., Kassem, A. A., Moustafa, M. A., Assiri, H., & El-Mahdy, A. M. (2024). Suppression of virulence factors of uropathogenic Escherichia coli by Trans-resveratrol and design of nanoemulgel. BMC Microbiology,24(1), 412. https:\/\/doi.org\/10.1186\/s12866-024-03538-4","journal-title":"BMC Microbiology"},{"issue":"11","key":"5894_CR58","doi-asserted-by":"publisher","first-page":"7779","DOI":"10.1039\/d3ra07835c","volume":"14","author":"M Sahoo","year":"2024","unstructured":"Sahoo, M., Behera, D. U., Sahoo, R. K., Sahoo, S., Dey, S., & Subudhi, E. (2024). Synergistic action of 6-gingerol as an adjuvant to colistin for susceptibility enhancement in multidrug-resistant Klebsiella pneumoniae isolates. RSC Advances,14(11), 7779\u201385. https:\/\/doi.org\/10.1039\/d3ra07835c","journal-title":"RSC Advances"},{"key":"5894_CR59","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.cimid.2018.03.001","volume":"57","author":"JFS dos Santos","year":"2018","unstructured":"dos Santos, J. F. S., Tintino, S. R., de Freitas, T. S., Campina, F. F., Irwin, I. R., Siqueira-J\u00fanior, J. P., & Cunha, F. A. B. (2018). In vitro e in silico evaluation of the inhibition of Staphylococcus aureus efflux pumps by caffeic and gallic acid. Comparative Immunology, Microbiology and Infectious Disease,57, 22\u20138. https:\/\/doi.org\/10.1016\/j.cimid.2018.03.001","journal-title":"Comparative Immunology, Microbiology and Infectious Disease"},{"key":"5894_CR60","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241511906","author":"A Dmitrieva","year":"2023","unstructured":"Dmitrieva, A., Kozlova, O., Atuchin, V., Milentieva, I., Vesnina, A., Ivanova, S., Asyakina, L., & Prosekov, A. (2023). Study of the effect of Baicalin from Scutellaria baicalensis on the gastrointestinal tract normoflora and Helicobacter pylori. International Journal of Molecular Sciences. https:\/\/doi.org\/10.3390\/ijms241511906","journal-title":"International Journal of Molecular Sciences"},{"key":"5894_CR61","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c06565","author":"Z Hu","year":"2024","unstructured":"Hu, Z., Shan, J., Jin, X., Sun, W., Cheng, L., Chen, X. L., & Wang, X. (2024). Nanoarchitectonics of in situ antibiotic-releasing acicular nanozymes for targeting and inducing cuproptosis-like death to eliminate drug-resistant bacteria. ACS Nano. https:\/\/doi.org\/10.1021\/acsnano.4c06565","journal-title":"ACS Nano"},{"issue":"10","key":"5894_CR62","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1099\/JMM.0.001060","volume":"68","author":"JW Betts","year":"2019","unstructured":"Betts, J. W., Hornsey, M., Higgins, P. G., Lucassen, K., Wille, J., Salguero, F. J., & la Ragione, R. M. (2019). Restoring the activity of the antibiotic aztreonam using the polyphenol epigallocatechin gallate (EGCG) against multidrug-resistant clinical isolates of Pseudomonas aeruginosa. Journal of Medical Microbiology,68(10), 1552\u20139. https:\/\/doi.org\/10.1099\/JMM.0.001060","journal-title":"Journal of Medical Microbiology"},{"key":"5894_CR63","doi-asserted-by":"publisher","DOI":"10.1111\/jam.15253","author":"D Buchmann","year":"2022","unstructured":"Buchmann, D., Schultze, N., Borchardt, J., B\u00f6ttcher, I., Schaufler, K., & Guenther, S. (2022). Synergistic antimicrobial activities of epigallocatechin gallate, myricetin, daidzein, gallic acid, epicatechin, 3-hydroxy-6-methoxyflavone and genistein combined with antibiotics against ESKAPE pathogens. Journal of Applied Microbiology. https:\/\/doi.org\/10.1111\/jam.15253","journal-title":"Journal of Applied Microbiology"},{"key":"5894_CR64","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11040518","author":"A Siriphap","year":"2022","unstructured":"Siriphap, A., Kiddee, A., Duangjai, A., Yosboonruang, A., Pook-In, G., Saokaew, S., Sutheinkul, O., & Rawangkan, A. (2022). Antimicrobial activity of the green tea polyphenol (\u2212)-epigallocatechin-3-gallate (EGCG) against clinical isolates of multidrug-resistant Vibrio cholerae. Antibiotics. https:\/\/doi.org\/10.3390\/antibiotics11040518","journal-title":"Antibiotics"},{"key":"5894_CR65","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1232039","author":"D Buchmann","year":"2023","unstructured":"Buchmann, D., Schwabe, M., Weiss, R., Kuss, A. W., Schaufler, K., Schl\u00fcter, R., R\u00f6diger, S., Guenther, S., & Schultze, N. (2023). Natural phenolic compounds as biofilm inhibitors of multidrug-resistant Escherichia coli \u2013 the role of similar biological processes despite structural diversity. Frontiers in Microbiology. https:\/\/doi.org\/10.3389\/fmicb.2023.1232039","journal-title":"Frontiers in Microbiology"},{"issue":"4","key":"5894_CR66","first-page":"345","volume":"11","author":"MS Aslam","year":"2017","unstructured":"Aslam, M. S., Ahmad, M. S., Ahmad, M. A., & Akhlaq, M. (2017). An updated review on phytochemical and pharmacological propeties of piper sarmentosum. Current Trends in Biotechnology and Pharmacy,11(4), 345\u201356.","journal-title":"Current Trends in Biotechnology and Pharmacy"},{"key":"5894_CR67","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.00911","author":"L Othman","year":"2019","unstructured":"Othman, L., Sleiman, A., & Abdel-Massih, R. M. (2019). Antimicrobial activity of polyphenols and alkaloids in Middle Eastern plants. Frontiers in Microbiology. https:\/\/doi.org\/10.3389\/fmicb.2019.00911","journal-title":"Frontiers in Microbiology"},{"key":"5894_CR68","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21101374","author":"D Lin","year":"2016","unstructured":"Lin, D., Xiao, M., Zhao, J., Li, Z., Xing, B., Li, X., Kong, M., Li, L., Zhang, Q., Liu, Y., Chen, H., Qin, W., Wu, H., & Chen, S. (2016). An overview of plant phenolic compounds and their importance in human nutrition and management of type 2 diabetes. Molecules. https:\/\/doi.org\/10.3390\/molecules21101374","journal-title":"Molecules"},{"key":"5894_CR69","doi-asserted-by":"publisher","unstructured":"Ali, A., Parisi, A., & Normanno, G. (2022). Polyphenols as Emerging Antimicrobial Agents. In Emerging Modalities in Mitigation of Antimicrobial Resistance. https:\/\/doi.org\/10.1007\/978-3-030-84126-3_10","DOI":"10.1007\/978-3-030-84126-3_10"},{"issue":"6","key":"5894_CR70","doi-asserted-by":"publisher","first-page":"576","DOI":"10.2174\/0115734064277579240328142639","volume":"20","author":"A Sharma","year":"2024","unstructured":"Sharma, A., Anurag, Kaur J., Kesharwani, A., & Parihar, V. K. (2024). Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance. Medicinal Chemistry,20(6), 576\u201396. https:\/\/doi.org\/10.2174\/0115734064277579240328142639","journal-title":"Medicinal Chemistry"},{"key":"5894_CR71","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24043277","author":"M Maisto","year":"2023","unstructured":"Maisto, M., Iannuzzo, F., Novellino, E., Schiano, E., Piccolo, V., & Tenore, G. C. (2023). Natural polyphenols for prevention and treatment of urinary tract infections. International Journal of Molecular Sciences. https:\/\/doi.org\/10.3390\/ijms24043277","journal-title":"International Journal of Molecular Sciences"},{"key":"5894_CR72","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.9b00694","author":"CS Chambers","year":"2020","unstructured":"Chambers, C. S., Viktorov\u00e1, J., \u0158eho\u0159ov\u00e1, K., Biedermann, D., Turkov\u00e1, L., MacEk, T., K\u0159en, V., & Valentov\u00e1, K. (2020). Defying multidrug resistance! Modulation of related transporters by flavonoids and flavonolignans. Journal of Agricultural and Food Chemistry. https:\/\/doi.org\/10.1021\/acs.jafc.9b00694","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"5894_CR73","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15102321","author":"M Miklasi\u0144ska-Majdanik","year":"2018","unstructured":"Miklasi\u0144ska-Majdanik, M., K\u0119pa, M., Wojtyczka, R. D., Idzik, D., & W\u0105sik, T. J. (2018). Phenolic compounds diminish antibiotic resistance of Staphylococcus aureus clinical strains. International Journal of Environmental Research and Public Health. https:\/\/doi.org\/10.3390\/ijerph15102321","journal-title":"International Journal of Environmental Research and Public Health"},{"key":"5894_CR74","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.883839","author":"T Suganya","year":"2022","unstructured":"Suganya, T., Packiavathy, I. A. S. V., Aseervatham, G. S. B., Carmona, A., Rashmi, V., Mariappan, S., Devi, N. R., & Ananth, D. A. (2022). Tackling multiple-drug-resistant bacteria with conventional and complex phytochemicals. Frontiers in Cellular and Infection Microbiology. https:\/\/doi.org\/10.3389\/fcimb.2022.883839","journal-title":"Frontiers in Cellular and Infection Microbiology"},{"key":"5894_CR75","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02482-19","author":"Y Adewunmi","year":"2020","unstructured":"Adewunmi, Y., Namjilsuren, S., Walker, W. D., Amato, D. N., Amato, D. V., Mavrodi, O. V., Patton, D. L., & Mavrodi, D. V. (2020). Antimicrobial activity of, and cellular pathways targeted by, p-anisaldehyde and epigallocatechin gallate in the opportunistic human pathogen Pseudomonas aeruginosa. Applied and Environmental Microbiology. https:\/\/doi.org\/10.1128\/AEM.02482-19","journal-title":"Applied and Environmental Microbiology"},{"issue":"2","key":"5894_CR76","doi-asserted-by":"publisher","first-page":"188","DOI":"10.3390\/antiox10020188","volume":"10","author":"M Makarewicz","year":"2021","unstructured":"Makarewicz, M., Dro\u017cd\u017c, I., Tarko, T., & Duda-Chodak, A. (2021). The interactions between polyphenols and microorganisms, especially gut microbiota. Antioxidants,10(2), 188. https:\/\/doi.org\/10.3390\/antiox10020188","journal-title":"Antioxidants"},{"key":"5894_CR77","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1016\/j.ijbiomac.2017.05.071","volume":"103","author":"M Bilal","year":"2017","unstructured":"Bilal, M., Rasheed, T., Iqbal, H. M., Hu, H., Wang, W., & Zhang, X. (2017). Macromolecular agents with antimicrobial potentialities: A drive to combat antimicrobial resistance. International Journal of Biological Macromolecules,103, 554\u201374.","journal-title":"International Journal of Biological Macromolecules"},{"issue":"2","key":"5894_CR78","doi-asserted-by":"publisher","first-page":"160","DOI":"10.3390\/antibiotics11020160","volume":"11","author":"A Ramata-Stunda","year":"2022","unstructured":"Ramata-Stunda, A., Petrina, Z., Valkovska, V., Borodu\u0161kis, M., Gibnere, L., Gurkovska, E., & Nikolajeva, V. (2022). Synergistic Effect of Polyphenol-Rich Complex of Plant and Green Propolis Extracts with Antibiotics against Respiratory Infections Causing Bacteria. Antibiotics,11(2), 160. https:\/\/doi.org\/10.3390\/antibiotics11020160","journal-title":"Antibiotics"},{"key":"5894_CR79","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-019-0559-6","author":"B Khameneh","year":"2019","unstructured":"Khameneh, B., Iranshahy, M., Soheili, V., & Fazly Bazzaz, B. S. (2019). Review on plant antimicrobials: A mechanistic viewpoint. Antimicrobial Resistance and Infection Control. https:\/\/doi.org\/10.1186\/s13756-019-0559-6","journal-title":"Antimicrobial Resistance and Infection Control"},{"key":"5894_CR80","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1678979","author":"NT Hashim","year":"2025","unstructured":"Hashim, N. T., Babiker, R., Padmanabhan, V., Islam, M. S., Mohammed, R., Priya, S. P., Chaitanya, N. C. S. K., Parveen Dasnadi, S., Ahmed, A., Gobara Gismalla, B., & Rahman, M. M. (2025). Polyphenolic compounds in combating MDR periodontal pathogens: Current research and future directions. Frontiers in Pharmacology. https:\/\/doi.org\/10.3389\/fphar.2025.1678979","journal-title":"Frontiers in Pharmacology"},{"key":"5894_CR81","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-019-0268-7","author":"M Ghosh","year":"2020","unstructured":"Ghosh, M., Miller, P. A., & Miller, M. J. (2020). Antibiotic repurposing: Bis-catechol- and mixed ligand (bis-catechol-mono-hydroxamate)-teicoplanin conjugates are active against multidrug resistant Acinetobacter baumannii. Journal of Antibiotics. https:\/\/doi.org\/10.1038\/s41429-019-0268-7","journal-title":"Journal of Antibiotics"},{"key":"5894_CR82","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/3663315","author":"N Jubair","year":"2021","unstructured":"Jubair, N., Rajagopal, M., Chinnappan, S., Abdullah, N. B., & Fatima, A. (2021). Review on the antibacterial mechanism of plant-derived compounds against multidrug-resistant bacteria (MDR). Evidence-Based Complementary and Alternative Medicine. https:\/\/doi.org\/10.1155\/2021\/3663315","journal-title":"Evidence-Based Complementary and Alternative Medicine"},{"key":"5894_CR83","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2012.752342","author":"G Cirillo","year":"2016","unstructured":"Cirillo, G., Curcio, M., Vittorio, O., Iemma, F., Restuccia, D., Spizzirri, U. G., Puoci, F., & Picci, N. (2016). Polyphenol conjugates and human health: A perspective review. Critical Reviews in Food Science and Nutrition. https:\/\/doi.org\/10.1080\/10408398.2012.752342","journal-title":"Critical Reviews in Food Science and Nutrition"},{"key":"5894_CR84","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202007356","author":"Y Guo","year":"2021","unstructured":"Guo, Y., Sun, Q., Wu, F. G., Dai, Y., & Chen, X. (2021). Polyphenol-containing nanoparticles: Synthesis, properties, and therapeutic delivery. Advanced Materials. https:\/\/doi.org\/10.1002\/adma.202007356","journal-title":"Advanced Materials"},{"key":"5894_CR85","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2023.109221","author":"S Sahraeian","year":"2024","unstructured":"Sahraeian, S., Rashidinejad, A., & Golmakani, M. T. (2024). Recent advances in the conjugation approaches for enhancing the bioavailability of polyphenols. Food Hydrocolloids. https:\/\/doi.org\/10.1016\/j.foodhyd.2023.109221","journal-title":"Food Hydrocolloids"},{"key":"5894_CR86","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2022.2067830","author":"SS Nassarawa","year":"2023","unstructured":"Nassarawa, S. S., Nayik, G. A., Gupta, S. D., Areche, F. O., Jagdale, Y. D., Ansari, M. J., Hemeg, H. A., AL-Farga, A., & Alotaibi, S. S. (2023). Chemical aspects of polyphenol-protein interactions and their antibacterial activity. Critical Reviews in Food Science and Nutrition. https:\/\/doi.org\/10.1080\/10408398.2022.2067830","journal-title":"Critical Reviews in Food Science and Nutrition"},{"key":"5894_CR87","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c07579","author":"F Khan","year":"2021","unstructured":"Khan, F., Bamunuarachchi, N. I., Tabassum, N., & Kim, Y. M. (2021). Caffeic acid and its derivatives: Antimicrobial drugs toward microbial pathogens. Journal of Agricultural and Food Chemistry. https:\/\/doi.org\/10.1021\/acs.jafc.0c07579","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"5894_CR88","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2019.111871","author":"BO Oyedemi","year":"2019","unstructured":"Oyedemi, B. O., Kotsia, E. M., Stapleton, P. D., & Gibbons, S. (2019). Capsaicin and gingerol analogues inhibit the growth of efflux-multidrug resistant bacteria and R-plasmids conjugal transfer. Journal of Ethnopharmacology. https:\/\/doi.org\/10.1016\/j.jep.2019.111871","journal-title":"Journal of Ethnopharmacology"},{"key":"5894_CR89","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2023.100729","author":"C Liu","year":"2023","unstructured":"Liu, C., Dong, S., Wang, X., Xu, H., Yang, X., Wu, S., Jiang, X., Kan, M., & Xu, C. (2023). Research progress of polyphenols in nanoformulations for antibacterial application. Materials Today Bio. https:\/\/doi.org\/10.1016\/j.mtbio.2023.100729","journal-title":"Materials Today Bio"},{"key":"5894_CR90","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2020.112081","author":"EF de Oliveira","year":"2021","unstructured":"de Oliveira, E. F., Yang, X., Basnayake, N., Huu, C. N., Wang, L., Tikekar, R., & Nitin, N. (2021). Screening of antimicrobial synergism between phenolic acids derivatives and UV-A light radiation. Journal of Photochemistry and Photobiology B: Biology. https:\/\/doi.org\/10.1016\/j.jphotobiol.2020.112081","journal-title":"Journal of Photochemistry and Photobiology B: Biology"},{"issue":"8","key":"5894_CR91","doi-asserted-by":"publisher","first-page":"2157","DOI":"10.3390\/ijms19082157","volume":"19","author":"C Dasagrandhi","year":"2018","unstructured":"Dasagrandhi, C., Park, S., Jung, W. K., & Kim, Y. M. (2018). Antibacterial and biofilm modulating potential of ferulic acid-grafted chitosan against human pathogenic bacteria. International Journal of Molecular Sciences,19(8), 2157. https:\/\/doi.org\/10.3390\/ijms19082157","journal-title":"International Journal of Molecular Sciences"},{"key":"5894_CR92","doi-asserted-by":"publisher","first-page":"112609","DOI":"10.1016\/j.ejmech.2020.112609","volume":"204","author":"NA Zahrani","year":"2020","unstructured":"Zahrani, N. A., El-Shishtawy, R. M., & Asiri, A. M. (2020). Recent developments of gallic acid derivatives and their hybrids in medicinal chemistry: A review. European Journal of Medicinal Chemistry,204, 112609. https:\/\/doi.org\/10.1016\/j.ejmech.2020.112609","journal-title":"European Journal of Medicinal Chemistry"},{"issue":"3","key":"5894_CR93","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/j.jhazmat.2007.07.008","volume":"148","author":"DGJ Larsson","year":"2007","unstructured":"Larsson, D. G. J., de Pedro, C., & Paxeus, N. (2007). Effluent from drug manufactures contains extremely high levels of pharmaceuticals. Journal of Hazardous Materials,148(3), 751. https:\/\/doi.org\/10.1016\/j.jhazmat.2007.07.008","journal-title":"Journal of Hazardous Materials"},{"key":"5894_CR94","doi-asserted-by":"publisher","first-page":"115008","DOI":"10.1016\/j.ecoenv.2023.115008","volume":"259","author":"J Pan","year":"2023","unstructured":"Pan, J., Zheng, N., An, Q., Li, Y., Sun, S., Zhang, W., & Song, X. (2023). Effects of cadmium and copper mixtures on antibiotic resistance genes in rhizosphere soil. Ecotoxicology and Environmental Safety,259, 115008. https:\/\/doi.org\/10.1016\/j.ecoenv.2023.115008","journal-title":"Ecotoxicology and Environmental Safety"},{"key":"5894_CR95","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26094030","author":"A Duda-Madej","year":"2025","unstructured":"Duda-Madej, A., Viscardi, S., Niezg\u00f3dka, P., Szewczyk, W., & Wi\u0144ska, K. (2025). The impact of plant-derived polyphenols on combating efflux-mediated antibiotic resistance. International Journal of Molecular Sciences. https:\/\/doi.org\/10.3390\/ijms26094030","journal-title":"International Journal of Molecular Sciences"},{"issue":"10","key":"5894_CR96","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.3390\/life15101598","volume":"15","author":"H Al-Khalaifah","year":"2025","unstructured":"Al-Khalaifah, H., Rahman, M. H., Al-Surrayai, T., Al-Dhumair, A., & Al-Hasan, M. (2025). A One-Health Perspective of Antimicrobial Resistance (AMR): Human. Animals and Environmental Health. Life,15(10), 1598. https:\/\/doi.org\/10.3390\/life15101598","journal-title":"Animals and Environmental Health. Life"},{"key":"5894_CR97","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.117074","author":"B Chen","year":"2021","unstructured":"Chen, B., Han, J., Dai, H., & Jia, P. (2021). Biocide-tolerance and antibiotic-resistance in community environments and risk of direct transfers to humans: Unintended consequences of community-wide surface disinfecting during COVID-19? Environmental Pollution. https:\/\/doi.org\/10.1016\/j.envpol.2021.117074","journal-title":"Environmental Pollution"},{"key":"5894_CR98","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.158057","author":"D Qiu","year":"2022","unstructured":"Qiu, D., Ke, M., Zhang, Q., Zhang, F., Lu, T., Sun, L., & Qian, H. (2022). Response of microbial antibiotic resistance to pesticides: An emerging health threat. Science of the Total Environment. https:\/\/doi.org\/10.1016\/j.scitotenv.2022.158057","journal-title":"Science of the Total Environment"},{"key":"5894_CR99","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.116896","author":"MB Sathicq","year":"2021","unstructured":"Sathicq, M. B., Sabatino, R., Corno, G., & Di Cesare, A. (2021). Are microplastic particles a hotspot for the spread and the persistence of antibiotic resistance in aquatic systems? Environmental Pollution. https:\/\/doi.org\/10.1016\/j.envpol.2021.116896","journal-title":"Environmental Pollution"},{"key":"5894_CR100","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.6b00184","author":"LN Silva","year":"2016","unstructured":"Silva, L. N., Zimmer, K. R., Macedo, A. J., & Trentin, D. S. (2016). Plant natural products targeting bacterial virulence factors. Chemical Reviews. https:\/\/doi.org\/10.1021\/acs.chemrev.6b00184","journal-title":"Chemical Reviews"},{"key":"5894_CR101","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv1277","author":"D Szklarczyk","year":"2016","unstructured":"Szklarczyk, D., Santos, A., Von Mering, C., Jensen, L. J., Bork, P., & Kuhn, M. (2016). STITCH 5: Augmenting protein-chemical interaction networks with tissue and affinity data. Nucleic Acids Research. https:\/\/doi.org\/10.1093\/nar\/gkv1277","journal-title":"Nucleic Acids Research"},{"key":"5894_CR102","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv1070","author":"M Kanehisa","year":"2016","unstructured":"Kanehisa, M., Sato, Y., Kawashima, M., Furumichi, M., & Tanabe, M. (2016). KEGG as a reference resource for gene and protein annotation. Nucleic Acids Research. https:\/\/doi.org\/10.1093\/nar\/gkv1070","journal-title":"Nucleic Acids Research"},{"key":"5894_CR103","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1000","author":"D Szklarczyk","year":"2023","unstructured":"Szklarczyk, D., Kirsch, R., Koutrouli, M., Nastou, K., Mehryary, F., Hachilif, R., Gable, A. L., Fang, T., Doncheva, N., Pyysalo, S., Bork, P., Jensen, L., & Von Mering, C. (2023). The STRING database in 2023: Protein-protein association networks and functional enrichment analyses for any sequenced genome of interest. Nucleic Acids Research. https:\/\/doi.org\/10.1093\/nar\/gkac1000","journal-title":"Nucleic Acids Research"},{"key":"5894_CR104","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1239303","author":"P Shannon","year":"2003","unstructured":"Shannon, P., Markiel, A., Ozier, O., Baliga, N. S., Wang, J. T., Ramage, D., Amin, N., Schwikowski, B., & Ideker, T. (2003). Cytoscape: A software environment for integrated models of biomolecular interaction networks. Genome Research. https:\/\/doi.org\/10.1101\/gr.1239303","journal-title":"Genome Research"},{"key":"5894_CR105","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172273","author":"L Sanhueza","year":"2017","unstructured":"Sanhueza, L., Melo, R., Montero, R., Maisey, K., Mendoza, L., & Wilkens, M. (2017). Synergistic interactions between phenolic compounds identified in grape pomace extract with antibiotics of different classes against Staphylococcus aureus and Escherichia coli. PLoS ONE. https:\/\/doi.org\/10.1371\/journal.pone.0172273","journal-title":"PLoS ONE"},{"key":"5894_CR106","doi-asserted-by":"publisher","DOI":"10.1007\/s44371-025-00373-y","author":"OO Babalola","year":"2025","unstructured":"Babalola, O. O., Bridget, K., Oyubu, G., Waheed, S. A., Ajiboye, S. A., Fakayode, A. E., Edema, A. A., Chukwuma, U. G., Tiamiyu, R. T., Fakayode, A. J., Adebimpe, H. O., Onyeagba, K. D., Fakunle, C. O., Ottu, P. O., & Gabriel, S. (2025). Integrating phytochemicals and in silico methods for modern drug discovery: A comprehensive review. Discover Chemistry. https:\/\/doi.org\/10.1007\/s44371-025-00373-y","journal-title":"Discover Chemistry"},{"issue":"1","key":"5894_CR107","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1186\/s13104-017-2665-y","volume":"10","author":"IK Voukeng","year":"2017","unstructured":"Voukeng, I. K., Beng, V. P., & Kuete, V. (2017). Multidrug resistant bacteria are sensitive to Euphorbia prostrata and six others Cameroonian medicinal plants extracts. BMC Research Notes,10(1), 321. https:\/\/doi.org\/10.1186\/s13104-017-2665-y","journal-title":"BMC Research Notes"},{"key":"5894_CR108","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9100998","author":"A Borges","year":"2020","unstructured":"Borges, A., de Freitas, V., Mateus, N., Fernandes, I., & Oliveira, J. (2020). Solid lipid nanoparticles as carriers of natural phenolic compounds. Antioxidants. https:\/\/doi.org\/10.3390\/antiox9100998","journal-title":"Antioxidants"},{"key":"5894_CR109","doi-asserted-by":"publisher","DOI":"10.3390\/nu14010137","author":"D Plamada","year":"2022","unstructured":"Plamada, D., & Vodnar, D. C. (2022). Polyphenols\u2014gut microbiota interrelationship: A transition to a new generation of prebiotics. Nutrients. https:\/\/doi.org\/10.3390\/nu14010137","journal-title":"Nutrients"},{"key":"5894_CR110","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2023.1293633","author":"V Kumar","year":"2023","unstructured":"Kumar, V., Yasmeen, N., Pandey, A., Ahmad Chaudhary, A., Alawam, A. S., Ahmad Rudayni, H., Islam, A., Lakhawat, S. S., Sharma, P. K., & Shahid, M. (2023). Antibiotic adjuvants: Synergistic tool to combat multi-drug resistant pathogens. Frontiers in Cellular and Infection Microbiology. https:\/\/doi.org\/10.3389\/fcimb.2023.1293633","journal-title":"Frontiers in Cellular and Infection Microbiology"},{"key":"5894_CR111","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25204613","author":"B Yang","year":"2020","unstructured":"Yang, B., Dong, Y., Wang, F., & Zhang, Y. (2020). Nanoformulations to enhance the bioavailability and physiological functions of polyphenols. Molecules. https:\/\/doi.org\/10.3390\/molecules25204613","journal-title":"Molecules"},{"key":"5894_CR112","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-024-04376-7","author":"S Kiran","year":"2024","unstructured":"Kiran, S., Tariq, A., Iqbal, S., Naseem, Z., Siddique, W., Jabeen, S., Bashir, R., Hussain, A., Rahman, M., Habib, F.-e, Rauf, W., Ali, A., Sarwar, Y., Jander, G., & Iqbal, M. (2024). Punicalagin, a pomegranate polyphenol sensitizes the activity of antibiotics against three MDR pathogens of the Enterobacteriaceae. BMC Complementary Medicine and Therapies. https:\/\/doi.org\/10.1186\/s12906-024-04376-7","journal-title":"BMC Complementary Medicine and Therapies"},{"key":"5894_CR113","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6208","author":"F Farhadi","year":"2019","unstructured":"Farhadi, F., Khameneh, B., Iranshahi, M., & Iranshahy, M. (2019). Antibacterial activity of flavonoids and their structure\u2013activity relationship: An update review. Phytotherapy Research. https:\/\/doi.org\/10.1002\/ptr.6208","journal-title":"Phytotherapy Research"},{"key":"5894_CR114","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.02536","author":"S Qu","year":"2019","unstructured":"Qu, S., Dai, C., Shen, Z., Tang, Q., Wang, H., Zhai, B., Zhao, L., & Hao, Z. (2019). Mechanism of synergy between tetracycline and quercetin against antibiotic resistant Escherichia coli. Frontiers in Microbiology. https:\/\/doi.org\/10.3389\/fmicb.2019.02536","journal-title":"Frontiers in Microbiology"},{"key":"5894_CR115","doi-asserted-by":"publisher","first-page":"e0241304","DOI":"10.1371\/journal.pone.0241304","volume":"15","author":"C Vipin","year":"2020","unstructured":"Vipin, C., Saptami, K., Fida, F., Mujeeburahiman, M., Rao, S. S., Athmika, Arun AB., & Rekha, P. D. (2020). Potential synergistic activity of quercetin with antibiotics against multidrug-resistant clinical strains of Pseudomonas aeruginosa. PLoS ONE,15, e0241304. https:\/\/doi.org\/10.1371\/journal.pone.0241304","journal-title":"PLoS ONE"},{"issue":"6","key":"5894_CR116","doi-asserted-by":"publisher","first-page":"984","DOI":"10.3109\/13880209.2015.1091483","volume":"54","author":"J Shao","year":"2016","unstructured":"Shao, J., Zhang, M., Wang, T., Li, Y., & Wang, C. (2016). The roles of CDR1, CDR2, and MDR1 in kaempferol-induced suppression with fluconazole-resistant Candida albicans. Pharmaceutical Biology,54(6), 984\u201392. https:\/\/doi.org\/10.3109\/13880209.2015.1091483","journal-title":"Pharmaceutical Biology"},{"key":"5894_CR117","doi-asserted-by":"publisher","DOI":"10.3126\/ijasbt.v8i1.27313","author":"K Giri","year":"2020","unstructured":"Giri, K., Shrestha, B. K., Shakya, J., Sah, S. N., & Khanal, H. (2020). Antibacterial effect of green tea extract against multi drug resistant Escherichia coli isolated from urine sample of patients visiting tertiary care hospital of Eastern Nepal. International Journal of Applied Sciences and Biotechnology. https:\/\/doi.org\/10.3126\/ijasbt.v8i1.27313","journal-title":"International Journal of Applied Sciences and Biotechnology"},{"key":"5894_CR118","doi-asserted-by":"publisher","first-page":"19710","DOI":"10.1038\/srep19710","volume":"6","author":"J Gopal","year":"2016","unstructured":"Gopal, J., Muthu, M., Paul, D., Kim, D. H., & Chun, S. (2016). Bactericidal activity of green tea extracts: The importance of catechin containing nano particles. Scientific Reports,6, 19710. https:\/\/doi.org\/10.1038\/srep19710","journal-title":"Scientific Reports"},{"issue":"10","key":"5894_CR119","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.2174\/0929867323666160304150522","volume":"23","author":"HY Mahmood","year":"2016","unstructured":"Mahmood, H. Y., Jamshidi, S., Mark Sutton, J., & Rahman, K. M. (2016). Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux Pumps. Current Medicinal Chemistry,23(10), 1062\u201381. https:\/\/doi.org\/10.2174\/0929867323666160304150522","journal-title":"Current Medicinal Chemistry"},{"key":"5894_CR120","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2014.995627","author":"MJ Matos","year":"2015","unstructured":"Matos, M. J., Vazquez-Rodriguez, S., Uriarte, E., & Santana, L. (2015). Potential pharmacological uses of chalcones: A patent review (from June 2011-2014). Expert Opinion on Therapeutic Patents. https:\/\/doi.org\/10.1517\/13543776.2014.995627","journal-title":"Expert Opinion on Therapeutic Patents"},{"key":"5894_CR121","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1453173","author":"H Koudokpon","year":"2018","unstructured":"Koudokpon, H., Armstrong, N., Dougnon, T. V., Fah, L., Hounsa, E., Bankol\u00e9, H. S., Loko, F., Chabri\u00e8re, E., & Rolain, J. M. (2018). Antibacterial activity of chalcone and dihydrochalcone compounds from Uvaria chamae roots against multidrug-resistant bacteria. BioMed Research International. https:\/\/doi.org\/10.1155\/2018\/1453173","journal-title":"BioMed Research International"},{"issue":"8","key":"5894_CR122","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1515\/chempap-2015-0113","volume":"69","author":"MS Alam","year":"2015","unstructured":"Alam, M. S., Rahman, S. M. M., & Lee, D. U. (2015). Synthesis, biological evaluation, quantitative-SAR and docking studies of novel chalcone derivatives as antibacterial and antioxidant agents. Chemical Papers,69(8), 1118\u201329. https:\/\/doi.org\/10.1515\/chempap-2015-0113","journal-title":"Chemical Papers"},{"issue":"3","key":"5894_CR123","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1111\/jam.13048","volume":"120","author":"C Babii","year":"2016","unstructured":"Babii, C., Bahrin, L. G., Neagu, A. N., Gostin, I., Mihasan, M., Birsa, L. M., & Stefan, M. (2016). Antibacterial activity and proposed action mechanism of a new class of synthetic tricyclic flavonoids. Journal of Applied Microbiology,120(3), 630\u20137. https:\/\/doi.org\/10.1111\/jam.13048","journal-title":"Journal of Applied Microbiology"},{"key":"5894_CR124","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2019.02.015","author":"M Vestergaard","year":"2019","unstructured":"Vestergaard, M., & Ingmer, H. (2019). Antibacterial and antifungal properties of resveratrol. International Journal of Antimicrobial Agents. https:\/\/doi.org\/10.1016\/j.ijantimicag.2019.02.015","journal-title":"International Journal of Antimicrobial Agents"},{"issue":"1","key":"5894_CR125","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1111\/jam.13315","volume":"122","author":"A Klan\u010dnik","year":"2017","unstructured":"Klan\u010dnik, A., \u0160iki\u0107 Poga\u010dar, M., Tro\u0161t, K., Tu\u0161ek \u017dnidari\u010d, M., Mozeti\u010d Vodopivec, B., & Smole Mo\u017eina, S. (2017). Anti-Campylobacter activity of resveratrol and an extract from waste Pinot noir grape skins and seeds, and resistance of Camp. jejuni planktonic and biofilm cells, mediated via the CmeABC efflux pump. Journal of Applied Microbiology,122(1), 65\u201377. https:\/\/doi.org\/10.1111\/jam.13315","journal-title":"Journal of Applied Microbiology"},{"key":"5894_CR126","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.compbiolchem.2015.09.006","volume":"59","author":"K Patel","year":"2015","unstructured":"Patel, K., Tyagi, C., Goyal, S., Jamal, S., Wahi, D., Jain, R., & Grover, A. (2015). Identification of chebulinic acid as potent natural inhibitor of M. tuberculosis DNA gyrase and molecular insights into its binding mode of action. Computational Biology and Chemistry,59, 37\u201347. https:\/\/doi.org\/10.1016\/j.compbiolchem.2015.09.006","journal-title":"Computational Biology and Chemistry"},{"issue":"15","key":"5894_CR127","doi-asserted-by":"publisher","first-page":"2100749","DOI":"10.1002\/advs.202100749","volume":"8","author":"M Song","year":"2021","unstructured":"Song, M., Liu, Y., Li, T., Liu, X., Hao, Z., Ding, S., & Shen, J. (2021). Plant Natural Flavonoids Against Multidrug Resistant Pathogens. Advanced Science,8(15), 2100749. https:\/\/doi.org\/10.1002\/advs.202100749","journal-title":"Advanced Science"},{"issue":"1","key":"5894_CR128","doi-asserted-by":"publisher","first-page":"7413504","DOI":"10.1155\/2018\/7413504","volume":"2018","author":"M K\u0229pa","year":"2018","unstructured":"K\u0229pa, M., Miklasi\u0144ska-Majdanik, M., Wojtyczka, R. D., Idzik, D., Korzeniowski, K., Smole\u0144-Dzirba, J., & Wasik, T. J. (2018). Antimicrobial potential of caffeic acid against staphylococcus aureus clinical strains. BioMed Research International,2018(1), 7413504. https:\/\/doi.org\/10.1155\/2018\/7413504","journal-title":"BioMed Research International"},{"key":"5894_CR129","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2016.08.004","author":"VN Lima","year":"2016","unstructured":"Lima, V. N., Oliveira-Tintino, C. D. M., Santos, E. S., Morais, L. P., Tintino, S. R., Freitas, T. S., Geraldo, Y. S., Pereira, R. L. S., Cruz, R. P., Menezes, I. R. A., & Coutinho, H. D. M. (2016). Antimicrobial and enhancement of the antibiotic activity by phenolic compounds: Gallic acid, caffeic acid and pyrogallol. Microbial Pathogenesis. https:\/\/doi.org\/10.1016\/j.micpath.2016.08.004","journal-title":"Microbial Pathogenesis"},{"issue":"6","key":"5894_CR130","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1002\/jobm.202100061","volume":"61","author":"MT Shaaban","year":"2021","unstructured":"Shaaban, M. T., Ghaly, M. F., & Fahmi, S. M. (2021). Antibacterial activities of hexadecanoic acid methyl ester and green-synthesized silver nanoparticles against multidrug-resistant bacteria. Journal of Basic Microbiology,61(6), 557\u201368. https:\/\/doi.org\/10.1002\/jobm.202100061","journal-title":"Journal of Basic Microbiology"},{"issue":"2","key":"5894_CR131","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1021\/jm501285x","volume":"58","author":"JJ Koh","year":"2015","unstructured":"Koh, J. J., Lin, S., Aung, T. T., Lim, F., Zou, H., Bai, Y., & Beuerman, R. W. (2015). Amino acid modified xanthone derivatives: Novel, highly promising membrane-active antimicrobials for multidrug-resistant gram-positive bacterial infections. Journal of Medicinal Chemistry,58(2), 739\u201352. https:\/\/doi.org\/10.1021\/jm501285x","journal-title":"Journal of Medicinal Chemistry"},{"key":"5894_CR132","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S213200","author":"A Shariati","year":"2019","unstructured":"Shariati, A., Asadian, E., Fallah, F., Azimi, T., Hashemi, A., Sharahi, J. Y., & Moghadam, M. T. (2019). Evaluation of nano-curcumin effects on expression levels of virulence genes and biofilm production of multidrug-resistant Pseudomonas aeruginosa isolated from burn wound infection in Tehran, Iran. Infection and Drug Resistance. https:\/\/doi.org\/10.2147\/IDR.S213200","journal-title":"Infection and Drug Resistance"},{"key":"5894_CR133","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c12151","author":"Y Chen","year":"2023","unstructured":"Chen, Y., Gao, Y., Huang, Y., Jin, Q., & Ji, J. (2023). Inhibiting quorum sensing by active targeted pH-sensitive nanoparticles for enhanced antibiotic therapy of biofilm-associated bacterial infections. ACS Nano. https:\/\/doi.org\/10.1021\/acsnano.2c12151","journal-title":"ACS Nano"},{"key":"5894_CR134","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1007\/s10876-022-02274-x","volume":"34","author":"H Zahmatkesh","year":"2023","unstructured":"Zahmatkesh, H., Mirpour, M., Zamani, H., & Rasti, B. (2023). Effect of Samarium Oxide Nanoparticles Fabricated by Curcumin on Efflux Pump and Virulence Genes Expression in MDR Pseudomonas aeruginosa and Staphylococcus aureus. Journal of Cluster Science,34, 1227\u201335. https:\/\/doi.org\/10.1007\/s10876-022-02274-x","journal-title":"Journal of Cluster Science"},{"issue":"4","key":"5894_CR135","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.3390\/molecules26041004","volume":"26","author":"O Srichaiyapol","year":"2021","unstructured":"Srichaiyapol, O., Thammawithan, S., Siritongsuk, P., Nasompag, S., Daduang, S., Klaynongsruang, S., & Patramanon, R. (2021). Tannic acid-stabilized silver nanoparticles used in biomedical application as an effective antimelioidosis and prolonged efflux pump inhibitor against melioidosis causative pathogen. Molecules,26(4), 1004. https:\/\/doi.org\/10.3390\/molecules26041004","journal-title":"Molecules"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05894-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12010-026-05894-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12010-026-05894-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:35:13Z","timestamp":1788924913000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12010-026-05894-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,9]]},"references-count":135,"alternative-id":["5894"],"URL":"https:\/\/doi.org\/10.1007\/s12010-026-05894-5","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,9]]},"assertion":[{"value":"20 August 2026","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2026","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Consent to Publish","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Clinical Trial Number","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":5,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no known conflicts of interest to declare for this publication.","order":6,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}