{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T16:29:33Z","timestamp":1781713773379,"version":"3.54.5"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1-3","license":[{"start":{"date-parts":[[2008,3,6]],"date-time":"2008-03-06T00:00:00Z","timestamp":1204761600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1007\/s12011-008-8117-8","type":"journal-article","created":{"date-parts":[[2008,3,5]],"date-time":"2008-03-05T14:54:08Z","timestamp":1204728848000},"page":"1-7","source":"Crossref","is-referenced-by-count":50,"title":["Trace Element Levels in Hashimoto Thyroiditis Patients with Subclinical Hypothyroidism"],"prefix":"10.1007","volume":"123","author":[{"given":"Muhammed","family":"Erdal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Sahin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Hasimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6khan","family":"Uckaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Kutlu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenan","family":"Saglam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,3,6]]},"reference":[{"issue":"2","key":"8117_CR1","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1001\/jama.291.2.239","volume":"291","author":"NF Col","year":"2004","unstructured":"Col NF, Surks MI, Daniels GH (2004) Subclinical thyroid disease: clinical applications. JAMA 291(2):239\u2013243","journal-title":"JAMA"},{"issue":"4","key":"8117_CR2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0025-6196(11)62389-6","volume":"76","author":"V Fatourechi","year":"2001","unstructured":"Fatourechi V (2001) Subclinical thyroid disease. Mayo Clin Proc 76(4):413\u2013416","journal-title":"Mayo Clin Proc"},{"key":"8117_CR3","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1210\/jcem.87.2.8182","volume":"87","author":"JG Hollowell","year":"2002","unstructured":"Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA, Braverman LE , Serum TSH (2002) T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 87:489\u2013499","journal-title":"J Clin Endocrinol Metab"},{"key":"8117_CR4","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1001\/archinte.160.4.526","volume":"160","author":"GJ Canaris","year":"2000","unstructured":"Canaris GJ, Manowitz NR, Mayor G, Ridgway EC (2000) The Colorado thyroid disease prevalence study. Arch Intern Med 160:526\u2013534","journal-title":"Arch Intern Med"},{"key":"8117_CR5","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1365-2265.1977.tb01340.x","volume":"7","author":"WM Tunbridge","year":"1977","unstructured":"Tunbridge WM, Evered DC, Hall R, Appleton D, Brewis M, Clark F, Evans JG, Young E, Bird T, Smith PA (1977) The spectrum of thyroid disease in a community: the Whickham survey. Clin Endocrinol (Oxf) 7:481\u2013493","journal-title":"Clin Endocrinol (Oxf)"},{"key":"8117_CR6","first-page":"1070","volume-title":"Werner & Ingbar\u2019s The Thyroid: a fundamental and clinical text, 8th edn","author":"DS Ross","year":"2005","unstructured":"Ross DS (2005) Subclinical hypothyroidism. In: Braverman LE, Utiger RD (eds) Werner & Ingbar\u2019s The Thyroid: a fundamental and clinical text, 8th edn. Williams & Wilkins, Philadelphia Lippincott, pp 1070\u201310785"},{"key":"8117_CR7","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/j.metabol.2004.05.016","volume":"53","author":"A Perez","year":"2004","unstructured":"Perez A, Cubero JM, Sucunza N, Ortega E, Arcelus R, Rodriguez-Espinosa J, Ordonez-Llanos J, Blanco-Vaca F (2004) Emerging cardiovascular risk factors in subclinical hypothyroidism: lack of change after restoration of euthyroidism. Metabolism 53:1512\u20131515","journal-title":"Metabolism"},{"key":"8117_CR8","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1136\/hrt.46.2.202","volume":"46","author":"M Tieche","year":"1981","unstructured":"Tieche M, Lupi GA, Gutzwiller F, Grob PJ, Studer H, Burgi H (1981) Borderline low thyroid function and thyroid autoimmunity. Risk factors for coronary heart disease? Br Heart J 46:202\u2013206","journal-title":"Br Heart J"},{"key":"8117_CR9","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1136\/bmj.290.6481.1555","volume":"290","author":"JW Dean","year":"1985","unstructured":"Dean JW, Fowler PB (1985) Exaggerated responsiveness to thyrotrophin releasing hormone: a risk factor in women with coronary artery disease. Br Med J 290:1555\u20131561","journal-title":"Br Med J"},{"key":"8117_CR10","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/gerona\/57.10.M658","volume":"57","author":"MM Mya","year":"2002","unstructured":"Mya MM, Aronow WS (2002) Subclinical hypothyroidism is associated with coronary artery disease in older persons. J Gerontol A Biol Sci Med Sci 57:658\u2013659","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"8117_CR11","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1210\/jc.2004-2173","volume":"90","author":"MD Ringel","year":"2005","unstructured":"Ringel MD, Mazzaferri EL (2005) Subclinical thyroid dysfunction\u2013can there be a consensus about the consensus? J Clin Endocrinol Metab 90:588\u2013590","journal-title":"J Clin Endocrinol Metab"},{"key":"8117_CR12","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/j.1365-2265.2004.02031.x","volume":"60","author":"DS Cooper","year":"2004","unstructured":"Cooper DS (2004) Subclinical thyroid disease: consensus or conundrum? Clin Endocrinol (Oxf) 60:410\u2013412","journal-title":"Clin Endocrinol (Oxf)"},{"key":"8117_CR13","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1001\/jama.291.2.228","volume":"291","author":"MI Surks","year":"2004","unstructured":"Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, Franklyn JA, Hershman JM, Burman KD, Denke MA, Gorman C, Cooper RS, Weissman NJ (2004) Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA 291:228\u2013238","journal-title":"JAMA"},{"key":"8117_CR14","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1210\/jc.2004-1231","volume":"90","author":"H Gharib","year":"2005","unstructured":"Gharib H, Tuttle RM, Baskin HJ, Fish LH, Singer PA, McDermott MT (2005) American Association of Clinical Endocrinologists; American Thyroid Association; The Endocrine Society Consensus Statement #1: Subclinical thyroid dysfunction: a joint statement on management from the American Association of Clinical Endocrinologists, the American Thyroid Association, and The Endocrine Society. J Clin Endocrinol Metab 90:581\u2013585","journal-title":"J Clin Endocrinol Metab"},{"key":"8117_CR15","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/1097-0142(19830901)52:5<868::AID-CNCR2820520521>3.0.CO;2-K","volume":"52","author":"EJ Margalioth","year":"1983","unstructured":"Margalioth EJ, Schenker JG, Chevion M (1983) Copper and Zinc levels in normal and malignant tissues. Cancer 52:868\u2013872","journal-title":"Cancer"},{"key":"8117_CR16","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1039\/an9952000817","volume":"120","author":"VY Zaichick","year":"1995","unstructured":"Zaichick VY, Tsyh AF, Vtyurini BM (1995) Trace elements and thyroid cancers. Analyst 120:817\u2013821","journal-title":"Analyst"},{"key":"8117_CR17","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S0025-7125(16)31861-2","volume":"60","author":"RI Henkin","year":"1976","unstructured":"Henkin RI (1976) Trace metals in endocrinology. Med Clin North Am 60:779\u2013797","journal-title":"Med Clin North Am"},{"key":"8117_CR18","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1055\/s-2007-979169","volume":"28","author":"A Kralik","year":"1996","unstructured":"Kralik A, Eder K, Kirchgessner M (1996) Influence of zinc and selenium deficiency on parameters relating to thyroid hormone metabolism. Horm Metab Res 28:223\u2013226","journal-title":"Horm Metab Res"},{"key":"8117_CR19","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/ajcn\/40.1.26","volume":"40","author":"K Aihara","year":"1984","unstructured":"Aihara K, Nishi Y, Hatano S, Kihara M, Yoshimitsu K, Takeichi N, Ho T, Ezaki H, Usui T (1984) Zinc, copper manganese and selenium metabolism in thyroid disease. Am J Clin Nutr 40:26\u201335","journal-title":"Am J Clin Nutr"},{"key":"8117_CR20","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF02924294","volume":"19","author":"G Leblondel","year":"1989","unstructured":"Leblondel G, Allain P (1989) Effects of thyroparathyroidectomy and of thyroxine and calcitonin on tissue distribution of twelve elements in the rat. Biol Trace Element Res 19:171\u2013183","journal-title":"Biol Trace Element Res"},{"key":"8117_CR21","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1210\/jcem.87.4.8421","volume":"87","author":"R Gartner","year":"2002","unstructured":"Gartner R, Gasnier BCH, Dietrich JW, Krebs B, Angstwurm MWA (2002) Selenium supplementation in patients with autoimmune thyroiditis decrease thyroid peroxidase antibodies concentrations. J Clin Endocrinol Metab 87:1687\u20131691","journal-title":"J Clin Endocrinol Metab"},{"key":"8117_CR22","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1530\/eje.0.1480389","volume":"148","author":"LH Duntas","year":"2003","unstructured":"Duntas LH, Mantzou E, Koutras DA (2003) Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis. Eur J Endocrinol 148:389\u2013393","journal-title":"Eur J Endocrinol"},{"key":"8117_CR23","first-page":"151","volume":"190","author":"O Turker","year":"2006","unstructured":"Turker O, Kumanlioglu K, Karapolat I, Dogan I (2006) Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses. J Clin Endocrinol Metab 190:151\u2013156","journal-title":"J Clin Endocrinol Metab"},{"key":"8117_CR24","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0140-6736(82)91028-5","volume":"2","author":"JT Salonen","year":"1982","unstructured":"Salonen JT, Alfthan G, Huttunen JK, Pikkarainen J, Puska P (1982) Association between cardiovascular death and myocardial-infarction and serum selenium in a matched-pair longitudinal study. Lancet 2:175\u2013179","journal-title":"Lancet"},{"key":"8117_CR25","volume-title":"Modern nutrition in health and disease,","author":"GA Clugston","year":"1994","unstructured":"Clugston GA, Hetzel BS (1994) Iodine. In: Shils ME, Olson JA, Shike M (eds) Modern nutrition in health and disease,. 8thth edn. Lea & Febiger, Philadelphia PA","edition":"8th edn"},{"key":"8117_CR26","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1080\/10408399609527748","volume":"36","author":"D Brigham","year":"1996","unstructured":"Brigham D, Beard J (1996) Iron and thermoregulation: a review. Crit Rev Food Sci Nutr 36:747\u2013763","journal-title":"Crit Rev Food Sci Nutr"},{"key":"8117_CR27","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1007\/BF01625694","volume":"35","author":"A Kralik","year":"1996","unstructured":"Kralik A, Kirchgessner M, Eder K (1996) Concentrations of thyroid hormones in serum and activity of hepatic 5- monodeiodinase in copper deficient rats. Z Ernaehrswiss 35:288\u2013291","journal-title":"Z Ernaehrswiss"},{"key":"8117_CR28","doi-asserted-by":"crossref","first-page":"128","DOI":"10.7326\/0003-4819-140-2-200401200-00015","volume":"140","author":"M Helfand","year":"2004","unstructured":"Helfand M (2004) Screening for subclinical thyroid dysfunction in non-pregnant adults: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 140:128\u2013141","journal-title":"Ann Intern Med"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-008-8117-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12011-008-8117-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-008-8117-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T01:27:29Z","timestamp":1559438849000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12011-008-8117-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,6]]},"references-count":28,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["8117"],"URL":"https:\/\/doi.org\/10.1007\/s12011-008-8117-8","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,6]]}}}