{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T15:09:12Z","timestamp":1773673752581,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2008,9,30]],"date-time":"2008-09-30T00:00:00Z","timestamp":1222732800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1007\/s12011-008-8235-3","type":"journal-article","created":{"date-parts":[[2008,9,29]],"date-time":"2008-09-29T07:20:56Z","timestamp":1222672856000},"page":"95-101","source":"Crossref","is-referenced-by-count":3,"title":["Early Effects on T lymphocyte Response to Iron Deficiency in Mice. Short Communication"],"prefix":"10.1007","volume":"127","author":[{"given":"Felipe","family":"Saldanha-Araujo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana M.","family":"Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,9,30]]},"reference":[{"key":"8235_CR1","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.jaci.2005.04.036","volume":"115","author":"S Cunningham-Rundles","year":"2005","unstructured":"Cunningham-Rundles S, McNeeley DF, Moon A (2005) Mechanisms of nutrient modulation of the immune response. J Allergy Clin Immunol 115:1119\u20131128","journal-title":"J Allergy Clin Immunol"},{"key":"8235_CR2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0092-8674(04)00343-5","volume":"117","author":"MW Hentze","year":"2004","unstructured":"Hentze MW, Muckenthaler MU, Andrews NC (2004) Balancing acts: molecular control of mammalian iron metabolism. Cell 117:285\u2013297","journal-title":"Cell"},{"key":"8235_CR3","doi-asserted-by":"crossref","first-page":"23637","DOI":"10.1074\/jbc.273.37.23637","volume":"273","author":"Y Ke","year":"1998","unstructured":"Ke Y, Wu J, Leibold EA, Walden WE, Theil EC (1998) Loops and bulge\/loops in iron-responsive element isoforms influence iron regulatory protein binding. Fine-tuning of mRNA regulation? J Biol Chem 273:23637\u201323640","journal-title":"J Biol Chem"},{"key":"8235_CR4","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1152\/physrev.1987.67.2.520","volume":"67","author":"HA Huebers","year":"1987","unstructured":"Huebers HA, Finch CA (1987) The physiology of transferrin and transferrin receptors. Physiol Rev 67:520\u2013582","journal-title":"Physiol Rev"},{"key":"8235_CR5","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/00000441-198702000-00007","volume":"293","author":"S Irie","year":"1987","unstructured":"Irie S, Tavassoli M (1987) Transferrin-mediated cellular iron uptake. Am J Med Sci 293:103\u2013111","journal-title":"Am J Med Sci"},{"key":"8235_CR6","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.bbr.2005.06.019","volume":"164","author":"R Eseh","year":"2005","unstructured":"Eseh R, Zimmerberg B (2005) Age-dependent effects of gestational and lactational iron deficiency on anxiety behavior in rats. Behav Brain Res 164:214\u2013221","journal-title":"Behav Brain Res"},{"key":"8235_CR7","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S1521-6926(02)90003-4","volume":"15","author":"SK Srai","year":"2002","unstructured":"Srai SK, Bomford A, McArdle HJ (2002) Iron transport across cell membranes: molecular understanding of duodenal and placental iron uptake. Best Pract Res Clin Haematol 15:243\u2013259","journal-title":"Best Pract Res Clin Haematol"},{"key":"8235_CR8","doi-asserted-by":"crossref","first-page":"616S","DOI":"10.1093\/jn\/131.2.616S","volume":"131","author":"SJ Oppenheimer","year":"2001","unstructured":"Oppenheimer SJ (2001) Iron and its relation to immunity and infectious disease. J Nutr 131:616S\u2013633S","journal-title":"J Nutr"},{"key":"8235_CR9","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ejphar.2004.11.060","volume":"509","author":"Y Zhao","year":"2005","unstructured":"Zhao Y, Li H, Gao Z, Xu H (2005) Effects of dietary baicalin supplementation on iron overload-induced mouse liver oxidative injury. Eur J Pharmacol 509:195\u2013200","journal-title":"Eur J Pharmacol"},{"key":"8235_CR10","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1002\/jcb.10206","volume":"86","author":"SR Kuvibidila","year":"2002","unstructured":"Kuvibidila SR, Porretta C (2002) Differential effects of iron deficiency on the expression of CD80 and CD86 costimulatory receptors in mitogen-treated and untreated murine spleen cells. J Cell Biochem 86:571\u2013582","journal-title":"J Cell Biochem"},{"issue":"9","key":"8235_CR11","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0196-0644(05)82571-5","volume":"19","author":"GM Gaddis","year":"1990","unstructured":"Gaddis GM, Gaddis ML (1990) Introduction to biostatistics: part 5, statistical inference techniques for hypothesis testing with nonparametric data. Ann Emerg Med 19(9):1054\u20131059","journal-title":"Ann Emerg Med"},{"key":"8235_CR12","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1568-9972(02)00143-X","volume":"2","author":"CL Bowlus","year":"2003","unstructured":"Bowlus CL (2003) The role of iron in T cell development and autoimmunity. Autoimmun Rev 2:73\u201378","journal-title":"Autoimmun Rev"},{"key":"8235_CR13","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1079\/BJN19940094","volume":"72","author":"FO Omara","year":"1994","unstructured":"Omara FO, Blakley BR (1994) The effects of iron deficiency and iron overload on cell-mediated immunity in the mouse. Br J Nutr 72:899\u2013909","journal-title":"Br J Nutr"},{"key":"8235_CR14","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF02790075","volume":"46","author":"FO Omara","year":"1994","unstructured":"Omara FO, Blakley BR (1994) The IgM and IgG antibody responses in iron-deficient and iron-loaded mice. Biol Trace Elem Res 46:155\u2013161","journal-title":"Biol Trace Elem Res"},{"key":"8235_CR15","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1093\/ajcn\/51.2.228","volume":"51","author":"S Kuvibidila","year":"1990","unstructured":"Kuvibidila S, Dardenne M, Savino W, Lepault F (1990) Influence of iron-deficiency anemia on selected thymus functions in mice: thymulin biological activity, T-cell subsets, and thymocyte proliferation. Am J Clin Nutr 51:228\u2013232","journal-title":"Am J Clin Nutr"},{"key":"8235_CR16","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1093\/jn\/131.7.2028","volume":"131","author":"SR Kuvibidila","year":"2001","unstructured":"Kuvibidila SR, Porretta C, Baliga BS (2001) Iron deficiency alters the progression of mitogen-treated murine splenic lymphocytes through the cell cycle. J Nutr 131:2028\u20132033","journal-title":"J Nutr"},{"key":"8235_CR17","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/jcb.10627","volume":"90","author":"S Kuvibidila","year":"2003","unstructured":"Kuvibidila S, Yu L, Ode D, Velez M, Gardner R, Warrier RP (2003) Effects of iron deficiency on the secretion of interleukin-10 by mitogen-activated and non-activated murine spleen cells. J Cell Biochem 90:278\u2013286","journal-title":"J Cell Biochem"},{"key":"8235_CR18","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/sj.thj.6200574","volume":"5","author":"C Ekiz","year":"2005","unstructured":"Ekiz C, Agaoglu L, Karakas Z, Gurel N, Yalcin L (2005) The effect of iron deficiency anemia on the function of the immune system. Hematol J 5:579\u2013583","journal-title":"Hematol J"},{"key":"8235_CR19","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1159\/000233199","volume":"69","author":"A Soyano","year":"1982","unstructured":"Soyano A, Candellet D, Layrisse M (1982) Effect of iron deficiency on the mitogen-induced proliferative response of rat lymphocytes. Int Arch Allergy Appl Immunol 69:353\u2013357","journal-title":"Int Arch Allergy Appl Immunol"},{"issue":"Suppl 3","key":"8235_CR20","doi-asserted-by":"crossref","first-page":"S46","DOI":"10.1038\/sj.ejcn.1601485","volume":"56","author":"W Savino","year":"2002","unstructured":"Savino W (2002) The thymus gland is a target in malnutrition. Eur J Clin Nutr 56(Suppl 3):S46\u2013S49","journal-title":"Eur J Clin Nutr"},{"key":"8235_CR21","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1046\/j.1365-2141.1999.01226.x","volume":"104","author":"ST Kinik","year":"1999","unstructured":"Kinik ST, Tuncer AM, Altay \u00c7 (1999) Transferrin receptor on peripheral blood lymphocytes in iron deficiency anemia. Br J Haematol 104:494\u2013498","journal-title":"Br J Haematol"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-008-8235-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12011-008-8235-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-008-8235-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T01:30:43Z","timestamp":1559439043000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12011-008-8235-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,30]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["8235"],"URL":"https:\/\/doi.org\/10.1007\/s12011-008-8235-3","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,30]]}}}