{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T06:58:32Z","timestamp":1779173912923,"version":"3.51.4"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1-3","license":[{"start":{"date-parts":[[2013,4,13]],"date-time":"2013-04-13T00:00:00Z","timestamp":1365811200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1007\/s12011-013-9654-3","type":"journal-article","created":{"date-parts":[[2013,4,12]],"date-time":"2013-04-12T02:26:38Z","timestamp":1365733598000},"page":"243-250","source":"Crossref","is-referenced-by-count":12,"title":["Effects of Dietary Factors on the Pharmacokinetics of 58Fe-labeled Hemin After Oral Administration in Normal Rats and the Iron-deficient Rats"],"prefix":"10.1007","volume":"153","author":[{"given":"Yongjie","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Di","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunxiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingwang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhua","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xijing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,4,13]]},"reference":[{"key":"9654_CR1","first-page":"671","volume":"75","author":"S Killip","year":"2007","unstructured":"Killip S, Bennett JM, Chambers MD (2007) Iron deficiency anemia. Am Fam Physician 75:671\u2013678","journal-title":"Am Fam Physician"},{"key":"9654_CR2","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/ajcn\/75.3.535","volume":"75","author":"L Davidsson","year":"2002","unstructured":"Davidsson L, Dimitriou T, Boy E, Walczyk T, Hurrell RF (2002) Iron bioavailability from iron-fortified Guatemalan meals based on corn tortillas and black bean paste. Am J Clin Nutr 75:535\u2013539","journal-title":"Am J Clin Nutr"},{"key":"9654_CR3","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/ajcn\/73.2.283","volume":"73","author":"L Davidsson","year":"2001","unstructured":"Davidsson L, Walczyk T, Zavaleta N, Hurrell RF (2001) Improving iron absorption from a Peruvian school breakfast meal by adding ascorbic acid or Na2EDTA. Am J Clin Nutr 73:283\u2013287","journal-title":"Am J Clin Nutr"},{"key":"9654_CR4","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1093\/ajcn\/84.4.830","volume":"84","author":"F Pizarro","year":"2006","unstructured":"Pizarro F, Olivares M, Hertrampf E, Nu\u00f1ez S, Tapia M, Cori H, de Romana DL (2006) Ascorbyl palmitate enhances iron bioavailability in iron-fortified bread. Am J Clin Nutr 84:830\u2013834","journal-title":"Am J Clin Nutr"},{"key":"9654_CR5","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1093\/ajcn\/71.4.937","volume":"74","author":"MB Reddy","year":"2000","unstructured":"Reddy MB, Hurrell RF, Cook JD (2000) Estimation of nonheme-iron bioavailability from meal composition. Am J Clin Nutr 74:937\u2013943","journal-title":"Am J Clin Nutr"},{"key":"9654_CR6","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1093\/jn\/138.9.1647","volume":"138","author":"EY Kim","year":"2008","unstructured":"Kim EY, Ham SK, Shigenaga MK, Han O (2008) Bioactive dietary polyphenolic compounds reduce nonheme iron transport across human intestinal cell monolayers. J Nutr 138:1647\u20131651","journal-title":"J Nutr"},{"key":"9654_CR7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/ajcn\/73.1.93","volume":"73","author":"JD Cook","year":"2001","unstructured":"Cook JD, Reddy MB (2001) Effects of ascorbic acid intake on nonheme-iron absorption from a complete diet. Am J Clin Nutr 73:93\u201398","journal-title":"Am J Clin Nutr"},{"key":"9654_CR8","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1021\/jf903177q","volume":"58","author":"S Miret","year":"2010","unstructured":"Miret S, Tascioglu S, Van Der Burg M, Frenken L, Klaffke W (2010) In vitro bioavailability of iron from the heme analogue sodium iron chlorophyllin. J Agric Food Chem 58:1327\u20131332","journal-title":"J Agric Food Chem"},{"key":"9654_CR9","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1111\/j.2042-7158.1987.tb05119.x","volume":"39","author":"R Tenhunen","year":"1987","unstructured":"Tenhunen R, Tokola O, Linden IB (1987) Haem arginate: a new stable haem compound. J Pharm Pharmacol 39:780\u2013786","journal-title":"J Pharm Pharmacol"},{"key":"9654_CR10","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1007\/s12325-008-0094-y","volume":"25","author":"SW Siegert","year":"2008","unstructured":"Siegert SW, Holt RJ (2008) Physicochemical properties, pharmacokinetics, and pharmacodynamics of intravenous hematin: a literature review. Adv Ther 25:842\u2013857","journal-title":"Adv Ther"},{"key":"9654_CR11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1742-7843.2004.pto940402.x","volume":"94","author":"AH Laftah","year":"2004","unstructured":"Laftah AH, Raja KB, Beaumont N, Simpson RJ, Deacon A, Solanky N, Srai SK, Peters TJ (2004) The effects of inhibition of haem biosynthesis by griseofulvin on intestinal iron absorption. Basic Clin Pharmacol Toxicol 94:161\u2013168","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"9654_CR12","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1017\/S0007114510005507","volume":"105","author":"P Masaratana","year":"2011","unstructured":"Masaratana P, Laftah AH, Latunde-Dada GO, Vaulont S, Simpson RJ, McKie AT (2011) Iron absorption in hepcidin1 knockout mice. Br J Nutr 105:1583\u20131591","journal-title":"Br J Nutr"},{"key":"9654_CR13","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jnutbio.2007.02.001","volume":"19","author":"S Kalgaonkar","year":"2008","unstructured":"Kalgaonkar S, L\u00f6nnerdal B (2008) Effects of dietary factors on iron uptake from ferritin in Caco-2 cells. J Nutr Biochem 19:33\u201339","journal-title":"J Nutr Biochem"},{"key":"9654_CR14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/ajcn\/79.1.99","volume":"79","author":"MC Fidler","year":"2004","unstructured":"Fidler MC, Davidsson L, Zeder C, Hurrell RF (2004) Erythorbic acid is a potent enhancer of nonheme-iron absorption. Am J Clin Nutr 79:99\u2013102","journal-title":"Am J Clin Nutr"},{"key":"9654_CR15","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s00394-011-0256-6","volume":"51","author":"V Fiorito","year":"2011","unstructured":"Fiorito V, Crich SG, Silengo L, Altruda F, Aime S, Tolosano E (2011) Assessment of iron absorption in mice by ICP-MS measurements of 57Fe levels. Eur J Nutr 51:783\u2013789","journal-title":"Eur J Nutr"},{"key":"9654_CR16","first-page":"03","volume":"148","author":"D Zhao","year":"2012","unstructured":"Zhao D, Zhang Y, Xu C, Dong C, Lin H, Zhang L, Li C, Ren S, Wang X, Yang S, Han D, Chen X (2012) Pharmacokinetics, tissue distribution, and plasma protein binding study of platinum originating from dicycloplatin, a novel antitumor supramolecule, in rats and dogs by ICP-MS. Biol Trace Elem Res 148:03\u2013208","journal-title":"Biol Trace Elem Res"},{"key":"9654_CR17","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1172\/JCI107881","volume":"54","author":"SB Raffin","year":"1974","unstructured":"Raffin SB, Woo CH, Roost KT, Price DC, Schmid R (1974) Intestinal absorption of hemoglobin iron-heme cleavage by mucosal heme oxygenase. J Clin Invest 54:1344\u20131352","journal-title":"J Clin Invest"},{"key":"9654_CR18","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S0140-6736(83)91337-5","volume":"1","author":"E Bjorn-Rasmussen","year":"1983","unstructured":"Bjorn-Rasmussen E (1983) Iron absorption: present knowledge and controversies. Lancet 1:914\u2013916","journal-title":"Lancet"},{"key":"9654_CR19","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1021\/jf052268l","volume":"54","author":"AK Proulx","year":"2006","unstructured":"Proulx AK, Reddy MB (2006) Iron bioavailability of hemoglobin from soy root nodules using a Caco-2 cell culture model. J Agric Food Chem 54:518\u20131522","journal-title":"J Agric Food Chem"},{"key":"9654_CR20","doi-asserted-by":"crossref","first-page":"838S","DOI":"10.1093\/jn\/127.5.838S","volume":"127","author":"PG Reeves","year":"1997","unstructured":"Reeves PG (1997) Components of the AIN-93 diets as improvements in the AIN-76A diet. J Nutr 127:838S\u2013841S","journal-title":"J Nutr"},{"key":"9654_CR21","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1248\/bpb.27.871","volume":"27","author":"T Akase","year":"2004","unstructured":"Akase T, Onodera S, Matsushita R, Akase T, Tashiro S (2004) A comparative study of laboratory parameters and symptoms effected by Toki-shakuyaku-san and an iron preparation in rats with iron-deficiency anemia. Biol Pharm Bull 27:871\u2013878","journal-title":"Biol Pharm Bull"},{"key":"9654_CR22","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s12011-012-9447-0","volume":"149","author":"J Fu","year":"2011","unstructured":"Fu J, Yang A, Ma Y, Liu M, Zhang L, Wang Y, Liu L (2011) The effect of fetal and early postnatal iron deficiency on iron metabolism in adult rats. Biol Trace Elem Res 149:412\u2013418","journal-title":"Biol Trace Elem Res"},{"key":"9654_CR23","doi-asserted-by":"crossref","first-page":"L1280","DOI":"10.1152\/ajplung.00004.2012","volume":"302","author":"VM Kumara","year":"2012","unstructured":"Kumara VM, Wessling-Resnick M (2012) Olfactory ferric and ferrous iron absorption in iron-deficient rats. Am J Physiol Lung Cell Mol Physiol 302:L1280\u2013L1286","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"9654_CR24","doi-asserted-by":"crossref","first-page":"G712","DOI":"10.1152\/ajpcell.1993.265.3.C712","volume":"265","author":"SK Roberts","year":"1993","unstructured":"Roberts SK, Henderson RW, Young GP (1993) Modulation of uptake of heme by rat small intestinal mucosa in iron deficiency. Am J Physiol 265:G712\u2013G718","journal-title":"Am J Physiol"},{"key":"9654_CR25","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.3748\/wjg.14.4101","volume":"14","author":"AR West","year":"2008","unstructured":"West AR, Oates PS (2008) Mechanisms of heme iron absorption: Current questions and controversies. World J Gastroenterol 14:4101\u20134110","journal-title":"World J Gastroenterol"},{"key":"9654_CR26","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1016\/S0024-3205(02)01556-4","volume":"70","author":"S Sakakibara","year":"2002","unstructured":"Sakakibara S, Aoyama Y (2002) Dietary iron-deficiency up-regulates hephaestin mRNA level in small intestine of rats. Life Sci 70:3123\u20133129","journal-title":"Life Sci"},{"key":"9654_CR27","doi-asserted-by":"crossref","first-page":"1461S","DOI":"10.3945\/ajcn.2010.28674F","volume":"91","author":"R Hurrell","year":"2010","unstructured":"Hurrell R, Egli I (2010) Iron bioavailability and dietary reference values. Am J Clin Nutr 91:1461S\u20131467S","journal-title":"Am J Clin Nutr"},{"key":"9654_CR28","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1079\/BJN19930053","volume":"69","author":"L Hallberg","year":"1993","unstructured":"Hallberg L, Rossander-Hulthen L, Brune M, Gleerup A (1993) Inhibition of haem-iron absorption in man by calcium. Br J Nutr 69:533\u2013540","journal-title":"Br J Nutr"},{"key":"9654_CR29","doi-asserted-by":"crossref","first-page":"H143","DOI":"10.1111\/j.1750-3841.2011.02184.x","volume":"76","author":"Q Ma","year":"2011","unstructured":"Ma Q, Kim EY, Lindsay EA, Han O (2011) Bioactive dietary polyphenols inhibit heme iron absorption in a dose-dependent manner in human intestinal caco-2 cells. J Food Sci 76:H143\u2013H150","journal-title":"J Food Sci"},{"key":"9654_CR30","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00394-011-0173-8","volume":"50","author":"P Villarroel","year":"2011","unstructured":"Villarroel P, Flores S, Pizarro F, de Roma\u00f1a DL, Arredondo M (2011) Effect of dietary protein on heme iron uptake by Caco-2 cells. Eur J Nutr 50:637\u2013643","journal-title":"Eur J Nutr"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-013-9654-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12011-013-9654-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-013-9654-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T09:05:39Z","timestamp":1562922339000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12011-013-9654-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,13]]},"references-count":30,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["9654"],"URL":"https:\/\/doi.org\/10.1007\/s12011-013-9654-3","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,13]]}}}