{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T13:11:42Z","timestamp":1774098702602,"version":"3.50.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2017,4,8]],"date-time":"2017-04-08T00:00:00Z","timestamp":1491609600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Iowa Osteopathic Educational Research Foundation","award":["3107"],"award-info":[{"award-number":["3107"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1007\/s12011-017-1019-x","type":"journal-article","created":{"date-parts":[[2017,4,8]],"date-time":"2017-04-08T02:44:39Z","timestamp":1491619479000},"page":"349-354","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Boric Acid Inhibition of Trichophyton rubrum Growth and Conidia Formation"],"prefix":"10.1007","volume":"180","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2654-9598","authenticated-orcid":false,"given":"Martin","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,4,8]]},"reference":[{"key":"1019_CR1","doi-asserted-by":"publisher","first-page":"374","DOI":"10.3109\/1040841X.2013.856853","volume":"41","author":"M Ilkit","year":"2015","unstructured":"Ilkit M, Durdu M (2015) Tinea pedis: the etiology and global epidemiology of a common fungal infection. Crit Rev Microbiol 41:374\u2013388. doi: 10.3109\/1040841X.2013.856853","journal-title":"Crit Rev Microbiol"},{"key":"1019_CR2","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s11046-013-9655-y","volume":"176","author":"A Hryncewicz-Gwozdz","year":"2013","unstructured":"Hryncewicz-Gwozdz A, Kalinowska K, Plomer-Niezgoda E, Bielecki J, Jagielski T (2013) Increase in resistance to fluconazole and itraconazole in Trichophyton rubrum clinical isolates by sequential passages in vitro under drug pressure. Mycopathologia 176:49\u201355. doi: 10.1007\/s11046-013-9655-y","journal-title":"Mycopathologia"},{"key":"1019_CR3","doi-asserted-by":"publisher","first-page":"342345","DOI":"10.1155\/2015\/342345","volume":"2015","author":"TF Fraga-Silva","year":"2015","unstructured":"Fraga-Silva TF, Marchetti CM, Mimura LA, Locachevic GA, Golim MA, Venturini J, Arruda MS (2015) Relationship among short and long term of hypoinsulinemia-hyperglycemia, dermatophytosis, and immunobiology of mononuclear phagocytes. Mediat Inflamm 2015:342345. doi: 10.1155\/2015\/342345","journal-title":"Mediat Inflamm"},{"key":"1019_CR4","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1089\/jwh.2010.2708","volume":"20","author":"C Iavazzo","year":"2011","unstructured":"Iavazzo C, Gkegkes ID, Zarkada IM, Falagas ME (2011) Boric acid for recurrent vulvovaginal candidiasis: the clinical evidence. J Women\u2019s Health (Larchmt) 20:1245\u20131255. doi: 10.1089\/jwh.2010.2708","journal-title":"J Women\u2019s Health (Larchmt)"},{"key":"1019_CR5","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/j.1749-4486.2012.02532.x","volume":"37","author":"JW Loock","year":"2012","unstructured":"Loock JW (2012) A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings. Clin Otolaryngol 37:261\u2013270. doi: 10.1111\/j.1749-4486.2012.02532.x","journal-title":"Clin Otolaryngol"},{"key":"1019_CR6","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1098\/rsnr.2013.0028","volume":"67","author":"M Worboys","year":"2013","unstructured":"Worboys M (2013) Joseph Lister and the performance of antiseptic surgery. Notes Rec R Soc Lond 67:199\u2013209. doi: 10.1098\/rsnr.2013.0028","journal-title":"Notes Rec R Soc Lond"},{"key":"1019_CR7","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1093\/jac\/dkn486","volume":"63","author":"F De Seta","year":"2009","unstructured":"De Seta F, Schmidt M, Vu B, Essmann M, Larsen B (2009) Antifungal mechanisms supporting boric acid therapy of Candida vaginitis. J Antimicrob Chemother 63:325\u2013336. doi: 10.1093\/jac\/dkn486","journal-title":"J Antimicrob Chemother"},{"key":"1019_CR8","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1097\/OLQ.0000000000000203","volume":"41","author":"A Brittingham","year":"2014","unstructured":"Brittingham A, Wilson WA (2014) The antimicrobial effect of boric acid on Trichomonas vaginalis. Sex Transm Dis 41:718\u2013722. doi: 10.1097\/OLQ.0000000000000203","journal-title":"Sex Transm Dis"},{"key":"1019_CR9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091878","volume":"9","author":"SE Ali","year":"2014","unstructured":"Ali SE, Thoen E, Evensen O, Skaar I (2014) Boric acid inhibits germination and colonization of Saprolegnia spores in vitro and in vivo. PLoS One 9:e91878. doi: 10.1371\/journal.pone.0091878","journal-title":"PLoS One"},{"key":"1019_CR10","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1006\/bbrc.1998.8688","volume":"246","author":"M Benderdour","year":"1998","unstructured":"Benderdour M, Hess K, Dzondo-Gadet M, Nabet P, Belleville F, Dousset B (1998) Boron modulates extracellular matrix and TNF alpha synthesis in human fibroblasts. Biochem Biophys Res Commun 246:746\u2013751","journal-title":"Biochem Biophys Res Commun"},{"key":"1019_CR11","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/S0946-672X(00)80006-1","volume":"14","author":"M Benderdour","year":"2000","unstructured":"Benderdour M, Van Bui T, Hess K, Dicko A, Belleville F, Dousset B (2000) Effects of boron derivatives on extracellular matrix formation. J Trace Elem Med Biol 14:168\u2013173. doi: 10.1016\/S0946-672X(00)80006-1","journal-title":"J Trace Elem Med Biol"},{"key":"1019_CR12","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0946-672X(02)80051-7","volume":"16","author":"RM Nzietchueng","year":"2002","unstructured":"Nzietchueng RM, Dousset B, Franck P, Benderdour M, Nabet P, Hess K (2002) Mechanisms implicated in the effects of boron on wound healing. J Trace Elem Med Biol 16:239\u2013244","journal-title":"J Trace Elem Med Biol"},{"key":"1019_CR13","volume-title":"Reference method for broth dilution antifungal susceptibility testing of filamentous fungi","author":"Clinical and Laboratory Standards Institute","year":"2008","unstructured":"Clinical and Laboratory Standards Institute (2008) Reference method for broth dilution antifungal susceptibility testing of filamentous fungi. Clinical Laboratory Standards Institute, Wayne"},{"key":"1019_CR14","doi-asserted-by":"crossref","unstructured":"Romsaithong S, Tomanakan K, Tangsawad W, Thanaviratananich S (2016) Effectiveness of 3 per cent boric acid in 70 per cent alcohol versus 1 per cent clotrimazole solution in otomycosis patients: a randomised, controlled trial. J Laryngol Otol 1\u20135","DOI":"10.1017\/S0022215116008598"},{"key":"1019_CR15","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1097\/IOP.0b013e3181610443","volume":"24","author":"JA Avino-Martinez","year":"2008","unstructured":"Avino-Martinez JA, Espana-Gregori E, Peris-Martinez CP, Blanes M (2008) Successful boric acid treatment of Aspergillus niger infection in an exenterated orbit. Ophthal Plast Reconstr Surg 24:79\u201381. doi: 10.1097\/IOP.0b013e3181610443","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"1019_CR16","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1111\/bjd.12594","volume":"170","author":"M Ghannoum","year":"2014","unstructured":"Ghannoum M, Isham N, Catalano V (2014) A second look at efficacy criteria for onychomycosis: clinical and mycological cure. Br J Dermatol 170:182\u2013187. doi: 10.1111\/bjd.12594","journal-title":"Br J Dermatol"},{"key":"1019_CR17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004105","volume":"10","author":"M Ghannoum","year":"2014","unstructured":"Ghannoum M, Isham N (2014) Fungal nail infections (onychomycosis): a never-ending story? PLoS Pathog 10:e1004105. doi: 10.1371\/journal.ppat.1004105","journal-title":"PLoS Pathog"},{"key":"1019_CR18","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1111\/ijd.13402","volume":"56","author":"Y Oz","year":"2017","unstructured":"Oz Y, Qoraan I, Oz A, Balta I (2017) Prevalence and epidemiology of tinea pedis and toenail onychomycosis and antifungal susceptibility of the causative agents in patients with type 2 diabetes in Turkey. Int J Dermatol 56:68\u201374. doi: 10.1111\/ijd.13402","journal-title":"Int J Dermatol"},{"key":"1019_CR19","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1006\/rtph.1995.0004","volume":"22","author":"FJ Murray","year":"1995","unstructured":"Murray FJ (1995) A human health risk assessment of boron (boric acid and borax) in drinking water. Regul Toxicol Pharmacol 22:221\u2013230","journal-title":"Regul Toxicol Pharmacol"},{"key":"1019_CR20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0890-6238(96)00204-3","volume":"11","author":"JA Moore","year":"1997","unstructured":"Moore JA (1997) An assessment of boric acid and borax using the IEHR evaluative process for assessing human developmental and reproductive toxicity of agents. Expert Scientific Committee. Reprod Toxicol 11:123\u2013160","journal-title":"Reprod Toxicol"},{"key":"1019_CR21","doi-asserted-by":"crossref","unstructured":"Reid RJ, Hayes JE, Post A, Stangoulis JCR, Graham RD (2004) A critical analysis of the causes of boron toxicity in plants 27:1405\u20131414","DOI":"10.1111\/j.1365-3040.2004.01243.x"},{"key":"1019_CR22","doi-asserted-by":"crossref","unstructured":"de Abreu Neto JB, Hurtado-Perez MC, Wimmer MA, Frei M (2016) Genetic factors underlying boron toxicity tolerance in rice: genome-wide association study and transcriptomic analysis. J Exp Bot","DOI":"10.1093\/jxb\/erw423"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12011-017-1019-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-017-1019-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-017-1019-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T16:27:58Z","timestamp":1568996878000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12011-017-1019-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,8]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1019"],"URL":"https:\/\/doi.org\/10.1007\/s12011-017-1019-x","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,8]]}}}